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Showing 1 to 12 of 21 entries
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Erratum to: Differential regulation of protein phosphatase 1 (PP1) isoforms in human heart failure and atrial fibrillation.

Basic research in cardiology

Meyer-Roxlau S, Lämmle S, Opitz A, Künzel S, Joos JP, Neef S, Sekeres K, Sossalla S, Schöndube F, Alexiou K, Maier LS, Dobrev D, Guan K, Weber S, El-Armouche A.
PMID: 28688054
Basic Res Cardiol. 2017 Sep;112(5):51. doi: 10.1007/s00395-017-0638-x.

No abstract available.

Loss of CASK Accelerates Heart Failure Development.

Circulation research

Mustroph J, Sag CM, Bähr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MMT, Lücht C, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, Möllmann J, Lehrke M, Marx N, Mohler PJ, Bers DM, Unsöld B, He T, Dewenter M, Backs J, Maier LS, Wagner S.
PMID: 33593074
Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17.

[Figure: see text].

LATITUDE-TIMI: is there still hope for anti-inflammatory therapy in acute myocardial infaction?.

Journal of thoracic disease

Dewenter M, Wagner M, El-Armouche A.
PMID: 27747059
J Thorac Dis. 2016 Sep;8(9):E1047-E1049. doi: 10.21037/jtd.2016.08.66.

No abstract available.

Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.

Circulation research

Künzel SR, Hoffmann M, Weber S, Künzel K, Kämmerer S, Günscht M, Klapproth E, Rausch JSE, Sadek MS, Kolanowski T, Meyer-Roxlau S, Piorkowski C, Tugtekin SM, Rose-John S, Yin X, Mayr M, Kuhlmann JD, Wimberger P, Grützmann K, Herzog N, Küpper JH, O'Reilly M, Kabir SN, Sommerfeld LC, Guan K, Wielockx B, Fabritz L, Nattel S, Ravens U, Dobrev D, Wagner M, El-Armouche A.
PMID: 34433292
Circ Res. 2021 Oct;129(8):804-820. doi: 10.1161/CIRCRESAHA.121.319425. Epub 2021 Aug 26.

[Figure: see text].

Electrophysiological Properties of Adult Zebrafish Oligodendrocyte Progenitor Cells.

Frontiers in cellular neuroscience

Tsata V, Kroehne V, Reinhardt S, El-Armouche A, Brand M, Wagner M, Reimer MM.
PMID: 31031593
Front Cell Neurosci. 2019 Apr 12;13:102. doi: 10.3389/fncel.2019.00102. eCollection 2019.

Low remyelination efficiency after spinal cord injury (SCI) is a major restraint to successful axonal and functional regeneration in mammals. In contrast, adult zebrafish can: (i) regenerate oligodendrocytes and myelin sheaths within 2 weeks post lesion; (ii) re-grow axonal...

Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control.

Cardiovascular research

Rathjens FS, Blenkle A, Iyer LM, Renger A, Syeda F, Noack C, Jungmann A, Dewenter M, Toischer K, El-Armouche A, Müller OJ, Fabritz L, Zimmermann WH, Zelarayan LC, Zafeiriou MP.
PMID: 32777030
Cardiovasc Res. 2021 Jul 07;117(8):1908-1922. doi: 10.1093/cvr/cvaa239.

AIMS: Arrhythmias and sudden cardiac death (SCD) occur commonly in patients with heart failure. We found T-box 5 (TBX5) dysregulated in ventricular myocardium from heart failure patients and thus we hypothesized that TBX5 reduction contributes to arrhythmia development in...

Function and regulation of phosphatase 1 in healthy and diseased heart.

Cellular signalling

Klapproth E, Kämmerer S, El-Armouche A.
PMID: 34822978
Cell Signal. 2021 Nov 22;90:110203. doi: 10.1016/j.cellsig.2021.110203. Epub 2021 Nov 22.

Reversible phosphorylation of ion channels and calcium-handling proteins provides precise post-translational regulation of cardiac excitation and contractility. Serine/threonine phosphatases govern dephosphorylation of the majority of cardiac proteins. Accordingly, dysfunction of this regulation contributes to the development and progression of...

Function and regulation of phosphatase 1 in healthy and diseased heart.

Cellular signalling

Klapproth E, Kämmerer S, El-Armouche A.
PMID: 34822978
Cell Signal. 2022 Feb;90:110203. doi: 10.1016/j.cellsig.2021.110203. Epub 2021 Nov 22.

Reversible phosphorylation of ion channels and calcium-handling proteins provides precise post-translational regulation of cardiac excitation and contractility. Serine/threonine phosphatases govern dephosphorylation of the majority of cardiac proteins. Accordingly, dysfunction of this regulation contributes to the development and progression of...

The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme

Bornstein SR, Guan K, Brunßen C, Mueller G, Kamvissi-Lorenz V, Lechler R, Trembath R, Mayr M, Poston L, Sancho R, Ahmed S, Alfar E, Aljani B, Alves TC, Amiel S, Andoniadou CL, Bandral M, Belavgeni A, Berger I, Birkenfeld A, Bonifacio E, Chavakis T, Chawla P, Choudhary P, Cujba AM, Delgadillo Silva LF, Demcollari T, Drotar DM, Duin S, El-Agroudy NN, El-Armouche A, Eugster A, Gado M, Gavalas A, Gelinsky M, Guirgus M, Hansen S, Hanton E, Hasse M, Henneicke H, Heller C, Hempel H, Hogstrand C, Hopkins D, Jarc L, Jones PM, Kamel M, Kämmerer S, King AJF, Kurzbach A, Lambert C, Latunde-Dada Y, Lieberam I, Liers J, Li JW, Linkermann A, Locke S, Ludwig B, Manea T, Maremonti F, Marinicova Z, McGowan BM, Mickunas M, Mingrone G, Mohanraj K, Morawietz H, Ninov N, Peakman M, Persaud SJ, Pietzsch J, Cachorro E, Pullen TJ, Pyrina I, Rubino F, Santambrogio A, Schepp F, Schlinkert P, Scriba LD, Siow R, Solimena M, Spagnoli FM, Speier S, Stavridou A, Steenblock C, Strano A, Taylor P, Tiepner A, Tonnus W, Tree T, Watt F, Werdermann M, Wilson M, Yusuf N, Ziegler CG.
PMID: 33652492
Horm Metab Res. 2021 Mar;53(3):204-206. doi: 10.1055/a-1377-6583. Epub 2021 Mar 02.

Currently, we are experiencing a true pandemic of a communicable disease by the virus SARS-CoV-2 holding the whole world firmly in its grasp. Amazingly and unfortunately, this virus uses a metabolic and endocrine pathway via ACE2 to enter our...

Loss of CASK Accelerates Heart Failure Development.

Circulation research

Mustroph J, Sag CM, Bähr F, Schmidtmann AL, Gupta SN, Dietz A, Islam MMT, Lücht C, Beuthner BE, Pabel S, Baier MJ, El-Armouche A, Sossalla S, Anderson ME, Möllmann J, Lehrke M, Marx N, Mohler PJ, Bers DM, Unsöld B, He T, Dewenter M, Backs J, Maier LS, Wagner S.
PMID: 33593074
Circ Res. 2021 Apr 16;128(8):1139-1155. doi: 10.1161/CIRCRESAHA.120.318170. Epub 2021 Feb 17.

[Figure: see text].

Function and regulation of phosphatase 1 in healthy and diseased heart.

Cellular signalling

Klapproth E, Kämmerer S, El-Armouche A.
PMID: 34822978
Cell Signal. 2021 Nov 22;90:110203. doi: 10.1016/j.cellsig.2021.110203. Epub 2021 Nov 22.

Reversible phosphorylation of ion channels and calcium-handling proteins provides precise post-translational regulation of cardiac excitation and contractility. Serine/threonine phosphatases govern dephosphorylation of the majority of cardiac proteins. Accordingly, dysfunction of this regulation contributes to the development and progression of...

Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein Phosphatases.

Frontiers in pharmacology

Weber S, Meyer-Roxlau S, Wagner M, Dobrev D, El-Armouche A.
PMID: 26617522
Front Pharmacol. 2015 Nov 13;6:270. doi: 10.3389/fphar.2015.00270. eCollection 2015.

Decades of cardiovascular research have shown that variable and flexible levels of protein phosphorylation are necessary to maintain cardiac function. A delicate balance between phosphorylated and dephosphorylated states of proteins is guaranteed by a complex interplay of protein kinases...

Showing 1 to 12 of 21 entries