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Showing 1 to 12 of 122 entries
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The Coags Uncomplicated App: Fulfilling Educational Gaps Around Diagnosis and Laboratory Testing of Coagulation Disorders.

JMIR medical education

Kessler C, Peerschke EI, Chitlur MB, Kulkarni R, Holot N, Cooper DL.
PMID: 28420603
JMIR Med Educ. 2017 Apr 18;3(1):e6. doi: 10.2196/mededu.6858.

BACKGROUND: Patients with coagulation disorders may present to a variety of physician specialties; however, accurate and efficient diagnosis can be challenging for physicians not specialized in hematology, due to identified gaps in knowledge around appropriate laboratory assays and interpretation...

Evaluation of 'Just4Mums' - A community based healthy eating and physical activity course for obese pregnant women.

Pregnancy hypertension

Olander EK, Atkinson L, French DP.
PMID: 26104626
Pregnancy Hypertens. 2014 Jul;4(3):236-7. doi: 10.1016/j.preghy.2014.03.023. Epub 2014 Jul 09.

UNLABELLED: Current NICE guidelines state that women in England need to be supported regarding eating healthily and being physically active during pregnancy. In response to these guidelines, the Just4Mums service was developed - a free six week community-based course...

CO.

Nature communications

Jones SW, Fast AG, Carlson ED, Wiedel CA, Au J, Antoniewicz MR, Papoutsakis ET, Tracy BP.
PMID: 27687501
Nat Commun. 2016 Sep 30;7:12800. doi: 10.1038/ncomms12800.

Maximizing the conversion of biogenic carbon feedstocks into chemicals and fuels is essential for fermentation processes as feedstock costs and processing is commonly the greatest operating expense. Unfortunately, for most fermentations, over one-third of sugar carbon is lost to...

Developmental influences on adult ovarian hormonal function.

American journal of human biology : the official journal of the Human Biology Council

Ellison PT.
PMID: 28561465
Am J Hum Biol. 1996;8(6):725-734. doi: 10.1002/(SICI)1520-6300(1996)8:6<725::AID-AJHB4>3.0.CO;2-S.

The hypothesis is advanced that levels of ovarian hormonal function in adult women are associated with the tempo of growth and maturation in childhood and adolescence. Empirical data are presented documenting a correlation between menarcheal age and adult ovarian...

Human male pair bonding and testosterone.

Human nature (Hawthorne, N.Y.)

Gray PB, Chapman JF, Burnham TC, McIntyre MH, Lipson SF, Ellison PT.
PMID: 26190409
Hum Nat. 2004 Jun;15(2):119-31. doi: 10.1007/s12110-004-1016-6.

Previous research in North America has supported the view that male involvement in committed, romantic relationships is associated with lower testosterone (T) levels. Here, we test the prediction that undergraduate men involved in committed, romantic relationships (paired) will have...

A Novel Transgenic Mouse Model of Cardiac Hypertrophy and Atrial Fibrillation.

Journal of atrial fibrillation

Rosenberg MA, Das S, Quintero Pinzon P, Knight AC, Sosnovik DE, Ellinor PT, Rosenzweig A.
PMID: 28496713
J Atr Fibrillation. 2012 Feb 02;4(5):415. doi: 10.4022/jafib.415. eCollection 2012.

Cardiac hypertrophy is a major risk factor for the development of atrial fibrillation (AF). However, there are few animal models of AF associated with cardiac hypertrophy. In this study, we describe the in vivo electrophysiological characteristics and histopathology of...

Illness in breastfeeding infants relates to concentration of lactoferrin and secretory Immunoglobulin A in mother's milk.

Evolution, medicine, and public health

Breakey AA, Hinde K, Valeggia CR, Sinofsky A, Ellison PT.
PMID: 25608691
Evol Med Public Health. 2015 Jan 20;2015(1):21-31. doi: 10.1093/emph/eov002.

BACKGROUND AND OBJECTIVES: This study aims to better understand the relationship between immune compounds in human milk and infant health. We hypothesized that the concentration of immune compounds in milk would relate to infant illness symptoms according to two...

Finding Web-Based Anxiety Interventions on the World Wide Web: A Scoping Review.

JMIR mental health

Ashford MT, Olander EK, Ayers S.
PMID: 27251763
JMIR Ment Health. 2016 Jun 01;3(2):e14. doi: 10.2196/mental.5349.

BACKGROUND: One relatively new and increasingly popular approach of increasing access to treatment is Web-based intervention programs. The advantage of Web-based approaches is the accessibility, affordability, and anonymity of potentially evidence-based treatment. Despite much research evidence on the effectiveness...

The genomics of heart failure: design and rationale of the HERMES consortium.

ESC heart failure

Lumbers RT, Shah S, Lin H, Czuba T, Henry A, Swerdlow DI, Mälarstig A, Andersson C, Verweij N, Holmes MV, Ärnlöv J, Svensson P, Hemingway H, Sallah N, Almgren P, Aragam KG, Asselin G, Backman JD, Biggs ML, Bloom HL, Boersma E, Brandimarto J, Brown MR, Brunner-La Rocca HP, Carey DJ, Chaffin MD, Chasman DI, Chazara O, Chen X, Chen X, Chung JH, Chutkow W, Cleland JGF, Cook JP, de Denus S, Dehghan A, Delgado GE, Denaxas S, Doney AS, Dörr M, Dudley SC, Engström G, Esko T, Fatemifar G, Felix SB, Finan C, Ford I, Fougerousse F, Fouodjio R, Ghanbari M, Ghasemi S, Giedraitis V, Giulianini F, Gottdiener JS, Gross S, Guðbjartsson DF, Gui H, Gutmann R, Haggerty CM, van der Harst P, Hedman ÅK, Helgadottir A, Hillege H, Hyde CL, Jacob J, Jukema JW, Kamanu F, Kardys I, Kavousi M, Khaw KT, Kleber ME, Køber L, Koekemoer A, Kraus B, Kuchenbaecker K, Langenberg C, Lind L, Lindgren CM, London B, Lotta LA, Lovering RC, Luan J, Magnusson P, Mahajan A, Mann D, Margulies KB, Marston NA, März W, McMurray JJV, Melander O, Melloni G, Mordi IR, Morley MP, Morris AD, Morris AP, Morrison AC, Nagle MW, Nelson CP, Newton-Cheh C, Niessner A, Niiranen T, Nowak C, O'Donoghue ML, Owens AT, Palmer CNA, Paré G, Perola M, Perreault LL, Portilla-Fernandez E, Psaty BM, Rice KM, Ridker PM, Romaine SPR, Roselli C, Rotter JI, Ruff CT, Sabatine MS, Salo P, Salomaa V, van Setten J, Shalaby AA, Smelser DT, Smith NL, Stefansson K, Stender S, Stott DJ, Sveinbjörnsson G, Tammesoo ML, Tardif JC, Taylor KD, Teder-Laving M, Teumer A, Thorgeirsson G, Thorsteinsdottir U, Torp-Pedersen C, Trompet S, Tuckwell D, Tyl B, Uitterlinden AG, Vaura F, Veluchamy A, Visscher PM, Völker U, Voors AA, Wang X, Wareham NJ, Weeke PE, Weiss R, White HD, Wiggins KL, Xing H, Yang J, Yang Y, Yerges-Armstrong LM, Yu B, Zannad F, Zhao F, Wilk JB, Holm H, Sattar N, Lubitz SA, Lanfear DE, Shah S, Dunn ME, Wells QS, Asselbergs FW, Hingorani AD, Dubé MP, Samani NJ, Lang CC, Cappola TP, Ellinor PT, Vasan RS, Smith JG.
PMID: 34480422
ESC Heart Fail. 2021 Sep 03; doi: 10.1002/ehf2.13517. Epub 2021 Sep 03.

AIMS: The HERMES (HEart failure Molecular Epidemiology for Therapeutic targetS) consortium aims to identify the genomic and molecular basis of heart failure.METHODS AND RESULTS: The consortium currently includes 51 studies from 11 countries, including 68 157 heart failure cases...

Early-Onset Atrial Fibrillation and the Prevalence of Rare Variants in Cardiomyopathy and Arrhythmia Genes.

JAMA cardiology

Yoneda ZT, Anderson KC, Quintana JA, O'Neill MJ, Sims RA, Glazer AM, Shaffer CM, Crawford DM, Stricker T, Ye F, Wells Q, Stevenson LW, Michaud GF, Darbar D, Lubitz SA, Ellinor PT, Roden DM, Shoemaker MB.
PMID: 34495297
JAMA Cardiol. 2021 Dec 01;6(12):1371-1379. doi: 10.1001/jamacardio.2021.3370.

IMPORTANCE: Early-onset atrial fibrillation (AF) can be the initial manifestation of a more serious underlying inherited cardiomyopathy or arrhythmia syndrome.OBJECTIVE: To examine the results of genetic testing for early-onset AF.DESIGN, SETTING, AND PARTICIPANTS: This prospective, observational cohort study enrolled...

Re-CHARGE-AF: Recalibration of the CHARGE-AF Model for Atrial Fibrillation Risk Prediction in Patients With Acute Stroke.

Journal of the American Heart Association

Ashburner JM, Wang X, Li X, Khurshid S, Ko D, Trisini Lipsanopoulos A, Lee PR, Carmichael T, Turner AC, Jackson C, Ellinor PT, Benjamin EJ, Atlas SJ, Singer DE, Trinquart L, Lubitz SA, Anderson CD.
PMID: 34666503
J Am Heart Assoc. 2021 Nov 02;10(21):e022363. doi: 10.1161/JAHA.121.022363. Epub 2021 Oct 20.

Background Performance of existing atrial fibrillation (AF) risk prediction models in poststroke populations is unclear. We evaluated predictive utility of an AF risk model in patients with acute stroke and assessed performance of a fully refitted model. Methods and...

Deep learning enables genetic analysis of the human thoracic aorta.

Nature genetics

Pirruccello JP, Chaffin MD, Chou EL, Fleming SJ, Lin H, Nekoui M, Khurshid S, Friedman SF, Bick AG, Arduini A, Weng LC, Choi SH, Akkad AD, Batra P, Tucker NR, Hall AW, Roselli C, Benjamin EJ, Vellarikkal SK, Gupta RM, Stegmann CM, Juric D, Stone JR, Vasan RS, Ho JE, Hoffmann U, Lubitz SA, Philippakis AA, Lindsay ME, Ellinor PT.
PMID: 34837083
Nat Genet. 2022 Jan;54(1):40-51. doi: 10.1038/s41588-021-00962-4. Epub 2021 Nov 26.

Enlargement or aneurysm of the aorta predisposes to dissection, an important cause of sudden death. We trained a deep learning model to evaluate the dimensions of the ascending and descending thoracic aorta in 4.6 million cardiac magnetic resonance images...

Showing 1 to 12 of 122 entries