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Showing 1 to 12 of 343 entries
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Deep evolutionary diversification of semicircular canals in archosaurs

STEM and diversification

Benson RBJ, Bronzati M, Evers SW.
GSID: _nXxSM1HJFEJ
M Bronzati, RBJ Benson, SW Evers, MD Ezcurra… - Current Biology, 2021 - Elsevier

… sampling of early fossils on key stem lineages. In particular, the … of both shape and size among stem-archosaurs and a deep … labyrinth occurring early on the bird stem-lineage (Figure 4). …

A new hypothesis of turtle relationships provides insights into the evolution of marine adaptation, and turtle diversification

STEM and diversification

Evers SW.
GSID: UjiTzosBZPMJ
SW Evers - geoscience-meeting.ch

Evolutionary transitions to marine habitats occurred frequently among Mesozoic reptiles, but chelonioid sea turtles are the only clade that survives to the present. Thus, chelonioids provide the chance to investigate macroevolutionary questions, such as the mode and tempo of...

Health economics and integrated care: a growing and challenging relationship.

International journal of integrated care

Evers SM, Paulus AT.
PMID: 26150762
Int J Integr Care. 2015 Jun 17;15:e024. doi: 10.5334/ijic.2201. eCollection 2015.

No abstract available.

Mental health assessments in refugees and asylum seekers: evaluation of a tablet-assisted screening software.

Conflict and health

Morina N, Ewers SM, Passardi S, Schnyder U, Knaevelsrud C, Müller J, Bryant RA, Nickerson A, Schick M.
PMID: 29026438
Confl Health. 2017 Oct 02;11:18. doi: 10.1186/s13031-017-0120-2. eCollection 2017.

BACKGROUND: Mental health problems resulting from persecution and forced migration are very common among refugees and asylum seekers and evolve into a major public health challenge in hosting societies. Language barriers often prevent timely access to appropriate health care,...

Applications of azo-based probes for imaging retinal hypoxia.

ACS medicinal chemistry letters

Uddin MI, Evans SM, Craft JR, Marnett LJ, Uddin MJ, Jayagopal A.
PMID: 25893047
ACS Med Chem Lett. 2015 Feb 12;6(4):445-9. doi: 10.1021/ml5005206. eCollection 2015 Apr 09.

We report the design and synthesis of an activatable molecular imaging probe to detect hypoxia in mouse models of retinal vascular diseases. Hypoxia of the retina has been associated with the initiation and progression of blinding retinal vascular diseases...

Mechanisms of blood flow and hypoxia production in rat 9L-epigastric tumors.

Tumor microenvironment and therapy

Koch CJ, Jenkins WT, Jenkins KW, Yang XY, Shuman AL, Pickup S, Riehl CR, Paudyal R, Poptani H, Evans SM.
PMID: 25436211
Tumor Microenviron Ther. 2013 Jan;1:1-13. doi: 10.2478/tumor-2012-0001.

Classical descriptions of tumor physiology suggest two origins for tumor hypoxia; steady-state (diffusion-limited) hypoxia and cycling (perfusion-modulated) hypoxia. Both origins, primarily studied and characterized in murine models, predict relatively small, isolated foci or thin shells of hypoxic tissue interspersed...

Tropical wetlands: A missing link in the global carbon cycle?.

Global biogeochemical cycles

Sjögersten S, Black CR, Evers S, Hoyos-Santillan J, Wright EL, Turner BL.
PMID: 26074666
Global Biogeochem Cycles. 2014 Dec;28(12):1371-1386. doi: 10.1002/2014GB004844. Epub 2014 Dec 04.

Tropical wetlands are not included in Earth system models, despite being an important source of methane (CH

Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines.

Oncoimmunology

Klein C, Waldhauer I, Nicolini VG, Freimoser-Grundschober A, Nayak T, Vugts DJ, Dunn C, Bolijn M, Benz J, Stihle M, Lang S, Roemmele M, Hofer T, van Puijenbroek E, Wittig D, Moser S, Ast O, Brünker P, Gorr IH, Neumann S, de Vera Mudry MC, Hinton H, Crameri F, Saro J, Evers S, Gerdes C, Bacac M, van Dongen G, Moessner E, Umaña P.
PMID: 28405498
Oncoimmunology. 2017 Jan 11;6(3):e1277306. doi: 10.1080/2162402X.2016.1277306. eCollection 2017.

We developed cergutuzumab amunaleukin (CEA-IL2v, RG7813), a novel monomeric CEA-targeted immunocytokine, that comprises a single IL-2 variant (IL2v) moiety with abolished CD25 binding, fused to the C-terminus of a high affinity, bivalent carcinoembryonic antigen (CEA)-specific antibody devoid of Fc-mediated...

Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure.

Frontiers in microbiology

Dever SM, Rodriguez M, Lapierre J, Costin BN, El-Hage N.
PMID: 26217309
Front Microbiol. 2015 Jul 06;6:653. doi: 10.3389/fmicb.2015.00653. eCollection 2015.

We investigated the role of autophagy in HIV-infected subjects with neurocognitive impairment (NCI) ± HIV encephalitis (HIVE), many of which had a history of polysubstance abuse/dependence, using post-mortem brain tissues to determine whether differences in autophagy related factors may...

Dissociation of yeast ribosomes; The effects of hydrostatic pressure and KCl.

Molecular biology reports

Amesz WJ, Bevers EM, Bloemers HP.
PMID: 24197428
Mol Biol Rep. 1973 Jun;1(1):33-9. doi: 10.1007/BF00357403.

The dissociation of free ribosomes at elevated concentrations of KCl is dependent on hydrostatic pressure. The pressure necessary for the dissociation is determined for KCl concentrations ranging from 0.1-0.4 M. It varies between 425 kg cm(-2) at 0.1 M...

Increased levels of urinary phenylacetylglycine associated with mitochondrial toxicity in a model of drug-induced phospholipidosis.

Therapeutic advances in drug safety

Doessegger L, Schmitt G, Lenz B, Fischer H, Schlotterbeck G, Atzpodien EA, Senn H, Suter L, Csato M, Evers S, Singer T.
PMID: 25083254
Ther Adv Drug Saf. 2013 Jun;4(3):101-14. doi: 10.1177/2042098613479393.

BACKGROUND: Phospholipidosis (PLD) is a lysosomal storage disorder induced by a class of cationic amphiphilic drugs. However, drug-induced PLD is reversible. Evidence of PLD from animal studies with some compounds has led to discontinuation of development. Regulatory authorities are...

Independent ion migration in suspensions of strongly interacting charged colloidal spheres.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Hessinger D, Evers M, Palberg T.
PMID: 11031602
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000 May;61(5):5493-506. doi: 10.1103/physreve.61.5493.

We report on systematic measurements of the low-frequency conductivity sigma in aqueous suspensions of highly charged colloidal spheres. Sample preparation in a closed tubing system results in precisely controlled number densities of 10(16) m-3 < or = n <...

Showing 1 to 12 of 343 entries