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Showing 1 to 10 of 10 entries
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Sorafenib plus tegafur-uracil (UFT) versus sorafenib as first line systemic treatment for patients with advanced stage HCC: a Phase II trial (ESLC01 study).

Journal of hepatocellular carcinoma

Azim HA, Omar A, Atef H, Zawahry H, Shaker MK, Abdelmaksoud AK, EzzElarab M, Abdel-Rahman O, Ismail M, Kassem L, Waked I.
PMID: 30510922
J Hepatocell Carcinoma. 2018 Nov 19;5:109-119. doi: 10.2147/JHC.S169285. eCollection 2018.

BACKGROUND: Phase II trials found that tegafur-uracil (UFT) is an effective drug in hepatocellular carcinoma (HCC), while preclinical data suggested that its combination with sorafenib may have a promising activity. Our Phase II randomized trial aimed to evaluate efficacy...

Care Bundle Approach to Reduce Surgical Site Infections in Acute Surgical Intensive Care Unit, Cairo, Egypt.

Infection and drug resistance

Wassef M, Mukhtar A, Nabil A, Ezzelarab M, Ghaith D.
PMID: 32095080
Infect Drug Resist. 2020 Jan 28;13:229-236. doi: 10.2147/IDR.S236814. eCollection 2020.

INTRODUCTION: Surgical site infections (SSIs) are one of the most frequently reported hospital acquired infections associated with significant spread of antibiotic resistance.PURPOSE: We aimed to evaluate a bundle-based approach in reducing SSI at acute surgical intensive care unit of...

Evaluation of TSEB turbulent fluxes using different methods for the retrieval of soil and canopy component temperatures from UAV thermal and multispectral imagery.

Irrigation science

Nieto H, Kustas WP, Torres-Rúa A, Alfieri JG, Gao F, Anderson MC, White WA, Song L, Del Mar Alsina M, Prueger JH, McKee M, Elarab M, McKee LG.
PMID: 32355404
Irrig Sci. 2019;37(3):389-406. doi: 10.1007/s00271-018-0585-9.

The thermal-based Two-Source Energy Balance (TSEB) model partitions the evapotranspiration (ET) and energy fluxes from vegetation and soil components providing the capability for estimating soil evaporation (E) and canopy transpiration (T). However, it is crucial for ET partitioning to...

Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.

Data in brief

Yamamoto T, Li Q, Hara H, Wang L, Zhou H, Li J, Eckhoff DE, Tector AJ, Klein EC, Lovingood R, Ezzelarab M, Ayares D, Wang Y, Cooper DKC, Iwase H.
PMID: 30294651
Data Brief. 2018 Sep 13;20:1965-1974. doi: 10.1016/j.dib.2018.08.213. eCollection 2018 Oct.

This report is related to the research article entitled "B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy" (Yamamoto et al., in press). Herein we provide the data regarding pig artery patch xenotransplantation into...

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.

Xenotransplantation

Foote JB, Jagdale A, Yamamoto T, Hara H, Bikhet MH, Schuurman HJ, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Fatima H, Eckhoff DE, Cooper DKC, Iwase H.
PMID: 34644438
Xenotransplantation. 2021 Oct 13; doi: 10.1111/xen.12715. Epub 2021 Oct 13.

INTRODUCTION: Pigs deficient in three glycosyltransferase enzymes (triple-knockout [TKO] pigs, that is, not expressing the three known carbohydrate xenoantigens) and expressing 'protective' human transgenes are considered a likely source of organs for transplantation into human recipients. Some human sera...

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons.

Xenotransplantation

Foote JB, Jagdale A, Yamamoto T, Hara H, Bikhet MH, Schuurman HJ, Nguyen HQ, Ezzelarab M, Ayares D, Anderson DJ, Fatima H, Eckhoff DE, Cooper DKC, Iwase H.
PMID: 34644438
Xenotransplantation. 2021 Nov;28(6):e12715. doi: 10.1111/xen.12715. Epub 2021 Oct 13.

INTRODUCTION: Pigs deficient in three glycosyltransferase enzymes (triple-knockout [TKO] pigs, that is, not expressing the three known carbohydrate xenoantigens) and expressing 'protective' human transgenes are considered a likely source of organs for transplantation into human recipients. Some human sera...

Attempted depletion of passenger leukocytes by irradiation in pigs.

Journal of transplantation

Tai HC, Zhu X, Lin YJ, Hara H, Ezzelarab M, Epperley M, Quader MA, Cooper DK.
PMID: 22220268
J Transplant. 2011;2011:928759. doi: 10.1155/2011/928759. Epub 2011 Dec 18.

Allograft/xenograft rejection is associated with "passenger leukocyte" migration from the organ into recipient lymph nodes. In Study 1, we attempted to deplete leukocytes from potential kidney "donor" pigs, using two regimens of total body irradiation. A dose of 700...

Inter-comparison of thermal measurements using ground-based sensors, UAV thermal cameras, and eddy covariance radiometers.

Proceedings of SPIE--the International Society for Optical Engineering

Torres-Rua A, Nieto H, Parry C, Elarab M, Collatz W, Coopmans C, McKee L, McKee M, Kustas W.
PMID: 31024191
Proc SPIE Int Soc Opt Eng. 2018 Jul 30;10664. doi: 10.1117/12.2305832. Epub 2018 Jul 16.

With the increasing availability of thermal proximity sensors, UAV-borne cameras, and eddy covariance radiometers there may be an assumption that information produced by these sensors is interchangeable or compatible. This assumption is often held for estimation of agricultural parameters...

The effect of local estrogen therapy on the urinary microbiome composition of postmenopausal women with and without recurrent urinary tract infections.

International urogynecology journal

Anglim B, Phillips C, Shynlova O, Alarab M.
PMID: 34003309
Int Urogynecol J. 2021 May 18; doi: 10.1007/s00192-021-04832-9. Epub 2021 May 18.

INTRODUCTION AND HYPOTHESIS: Recurrent urinary tract infections (rUTIs) occur in 2-10% of postmenopausal women. Local estrogen therapy (LET) has been shown to reduce UTIs. This study aimed to compare the urinary microbiome between patients with and without a history...

The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantation.

Journal of biomedical research

Cooper DK, Hara H, Ezzelarab M, Bottino R, Trucco M, Phelps C, Ayares D, Dai Y.
PMID: 23885264
J Biomed Res. 2013 Jul;27(4):249-53. doi: 10.7555/JBR.27.20130063. Epub 2013 Jun 12.

There is a critical shortage of organs, cells, and corneas from deceased human donors worldwide. There are also shortages of human blood for transfusion. A potential solution to all of these problems is the transplantation of organs, cells, and...

Showing 1 to 10 of 10 entries