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Showing 1 to 12 of 18 entries
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Emerging and Novel Functions of Complement Protein C1q.

Frontiers in immunology

Kouser L, Madhukaran SP, Shastri A, Saraon A, Ferluga J, Al-Mozaini M, Kishore U.
PMID: 26175731
Front Immunol. 2015 Jun 29;6:317. doi: 10.3389/fimmu.2015.00317. eCollection 2015.

Complement protein C1q, the recognition molecule of the classical pathway, performs a diverse range of complement and non-complement functions. It can bind various ligands derived from self, non-self, and altered self and modulate the functions of immune and non-immune...

Electronically and sterically tuned trans labilization controls the substitution behaviour of cobaloximes.

Dalton transactions (Cambridge, England : 2003)

Hamza MS, Felluga A, Randaccio L, Tauzher G, van Eldik R.
PMID: 15356725
Dalton Trans. 2004 Jan 21;(2):287-91. doi: 10.1039/b311263m. Epub 2003 Dec 03.

The kinetics of axial water substitution by cysteine in six different cobaloximes, viz.trans-RCo(Hdmg)(2)H(2)O, where Hdmg = dimethylglyoximate, R = cyclo-C(5)H(9) (c-P), CH(3)CH(2) (Et), CH(3) (Me), C(6)H(5)CH(2) (Bz), C(6)H(5) (Ph) and CF(3)CH(2), were studied as a function of cysteine concentration,...

Constitutive activation of the EGFR-STAT1 axis increases proliferation of meningioma tumor cells.

Neuro-oncology advances

Ferluga S, Baiz D, Hilton DA, Adams CL, Ercolano E, Dunn J, Bassiri K, Kurian KM, Hanemann CO.
PMID: 32642677
Neurooncol Adv. 2020 Jan 21;2(1):vdaa008. doi: 10.1093/noajnl/vdaa008. eCollection 2020.

BACKGROUND: Meningiomas are the most frequent primary brain tumors of the central nervous system. The standard of treatment is surgery and radiotherapy, but effective pharmacological options are not available yet. The well-characterized genetic background stratifies these tumors in several...

A new organocobalt complex containing a CO-N-C three membered ring.

Inorganic chemistry

Dreos R, Felluga A, Nardin G, Randaccio L, Siega P, Tauzher G.
PMID: 11599952
Inorg Chem. 2001 Oct 22;40(22):5541-6. doi: 10.1021/ic010418d.

Treatment of R = -CH(2)X (X = halogen) derivatives of the type [RCo(III)(LNH-py)(HLNH-py)](+), where HLNH-py = 2-(2-pyridyl-ethyl)amino-3-butanone oxime and LNH-py its conjugated base with diluted NaOH, afforded a new complex containing a three-membered ring by a pathway involving the...

High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy.

Critical care research and practice

Lucangelo U, Vassallo FG, Marras E, Ferluga M, Beziza E, Comuzzi L, Berlot G, Zin WA.
PMID: 22666567
Crit Care Res Pract. 2012;2012:506382. doi: 10.1155/2012/506382. Epub 2012 May 20.

During bronchoscopy hypoxemia is commonly found and oxygen supply can be delivered by interfaces fed with high gas flows. Recently, the high-flow nasal cannula (HFNC) has been introduced for oxygen therapy in adults, but they have not been used...

One-Pot Synthesis of Imidazole-4-Carboxylates by Microwave-Assisted 1,5-Electrocyclization of Azavinyl Azomethine Ylides.

European journal of organic chemistry

Preti L, Attanasi OA, Caselli E, Favi G, Ori C, Davoli P, Felluga F, Prati F.
PMID: 24273445
European J Org Chem. 2010 Aug;2010(22). doi: 10.1002/ejoc.201000434.

Diversely functionalized imidazole-4-carboxylates were synthesized by microwave-assisted 1,5-eletrocyclization of 1,2-diaza-1,3-diene-derived azavinyl azomethine ylides. 1,2-Diaza-1,3-dienes were treated with primary aliphatic or aromatic amines and subjected to microwave irradiation in the presence of aldehydes. 3-Alkyl- and 3-arylimidazole-4-carboxylates were prepared in good...

Dead space in acute respiratory distress syndrome.

Annals of translational medicine

Ferluga M, Lucangelo U, Blanch L.
PMID: 30460262
Ann Transl Med. 2018 Oct;6(19):388. doi: 10.21037/atm.2018.09.46.

Dead space is the portion of each tidal volume that does not take part in gas exchange and represents a good global index of the efficiency of the lung function. Dead space is not routinely measured in critical care...

Comprehensive Modelling of the Hysteresis Loops and Strain-Energy Density for Low-Cycle Fatigue-Life Predictions of the AZ31 Magnesium Alloy.

Materials (Basel, Switzerland)

Klemenc J, Šeruga D, Nagode A, Nagode M.
PMID: 31717407
Materials (Basel). 2019 Nov 08;12(22). doi: 10.3390/ma12223692.

Magnesium is one of the lightest metals for structural components. It has been used for producing various lightweight cast components, but the application of magnesium sheet plates is less widespread. There are two reasons for this: (i) its poor...

Optically active α-phenylethylamine as efficient organocatalyst in the solvent-free reactions between 2,3-butanedione and conjugated nitroolefins.

Chirality

Felluga F, Forzato C, Nitti P, Pitacco G, Prati F, Valentin E, Zangrando E.
PMID: 22836830
Chirality. 2012 Dec;24(12):1005-12. doi: 10.1002/chir.22088. Epub 2012 Jul 27.

(R)-(+) and (S)-(-)-1-phenylethylamine have been shown to promote highly diastereoselective and complementary enantioselective formal [3 + 2]carbocyclization reactions between 2,3-butanedione and conjugated nitroalkenes with formation of enantiomerically rich 2-hydroxy-3-nitrocyclopentanone derivatives. The reactions were carried out both in solvent and...

New alkyl-cobalt(III) complexes containing chiral centers in the chelating system.

Inorganic chemistry

Dreos R, Felluga A, Nardin G, Randaccio L, Sandri M, Tauzher G.
PMID: 12184773
Inorg Chem. 2002 Aug 26;41(17):4548-54. doi: 10.1021/ic025534a.

The complex mer-[Co(III)(L(1)Npy)(2)](+) (1') where the L(1)Npy(-) is the tridentate 3-[(2-pyridyl)methylimino]butan-2-one oximate ligand, gives alkyl-cobalt derivatives after reduction with NaBH(4)/Pd(2+) to the Co(I) and alkylation. The formation of the cobalt-carbon bond is accompanied by the reduction to the amino...

Human albumin eye drops as a therapeutic option for the management of keratoconjunctivitis sicca secondary to chronic graft-versus-host disease after stem-cell allografting.

Current oncology (Toronto, Ont.)

Seki JT, Sakurai N, Moldenhauer S, Dam J, Atenafu EG, Yip PM, Mazzulli T, Henderson T, Pendergrast J, Cserti C, Velazquez JP, Simpson R, Felluga G, Messner HA, Lipton JH.
PMID: 26628876
Curr Oncol. 2015 Oct;22(5):e357-63. doi: 10.3747/co.22.2620.

BACKGROUND: Keratoconjunctivitis sicca from chronic graft-versus-host disease (cgvhd) after allogeneic stem cell transplantation is common, leading to severe corneal damage and blindness if not treated. We retrospectively examined the efficacy and safety of pooled human albumin eye drops (haeds)...

Uncommon Occurrences of Air Embolism: Description of Cases and Review of the Literature.

Case reports in critical care

Berlot G, Rinaldi A, Moscheni M, Ferluga M, Rossini P.
PMID: 30073096
Case Rep Crit Care. 2018 Jul 08;2018:5808390. doi: 10.1155/2018/5808390. eCollection 2018.

Many different risk factors have been associated with the occurrence of gas embolism making this potentially lethal complication easily avoidable. However, this condition can occur in circumstances not commonly reported. Three different and extremely uncommon cases of gas embolism...

Showing 1 to 12 of 18 entries