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Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors.

Frontiers in immunology

Olmo IG, Carvalho TG, Costa VV, Alves-Silva J, Ferrari CZ, Izidoro-Toledo TC, da Silva JF, Teixeira AL, Souza DG, Marques JT, Teixeira MM, Vieira LB, Ribeiro FM.
PMID: 28878777
Front Immunol. 2017 Aug 23;8:1016. doi: 10.3389/fimmu.2017.01016. eCollection 2017.

Zika virus (ZIKV) has recently caused a worldwide outbreak of infections associated with severe neurological complications, including microcephaly in infants born from infected mothers. ZIKV exhibits high neurotropism and promotes neuroinflammation and neuronal cell death. We have recently demonstrated...

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Olmo IG, Carvalho TG, Costa VV, et al. Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors. Front Immunol. 2017;8:1016doi: 10.3389/fimmu.2017.01016.
Olmo, I. G., Carvalho, T. G., Costa, V. V., Alves-Silva, J., Ferrari, C. Z., Izidoro-Toledo, T. C., da Silva, J. F., Teixeira, A. L., Souza, D. G., Marques, J. T., Teixeira, M. M., Vieira, L. B., & Ribeiro, F. M. (2017). Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors. Frontiers in immunology, 81016. https://doi.org/10.3389/fimmu.2017.01016
Olmo, Isabella G, et al. "Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors." Frontiers in immunology vol. 8 (2017): 1016. doi: https://doi.org/10.3389/fimmu.2017.01016
Olmo IG, Carvalho TG, Costa VV, Alves-Silva J, Ferrari CZ, Izidoro-Toledo TC, da Silva JF, Teixeira AL, Souza DG, Marques JT, Teixeira MM, Vieira LB, Ribeiro FM. Zika Virus Promotes Neuronal Cell Death in a Non-Cell Autonomous Manner by Triggering the Release of Neurotoxic Factors. Front Immunol. 2017 Aug 23;8:1016. doi: 10.3389/fimmu.2017.01016. eCollection 2017. PMID: 28878777; PMCID: PMC5572413.
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Erratum to: Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase.

Journal of experimental & clinical cancer research : CR

Di Filippo F, Di Filippo S, Ferrari AM, Antonetti R, Battaglia A, Becherini F, Bernet L, Boldorini R, Bouteille C, Buglioni S, Burelli P, Cano R, Canzonieri V, Chiodera P, Cirilli A, Coppola L, Drago S, Di Tommaso L, Fenaroli P, Franchini R, Gianatti A, Giannarelli D, Giardina C, Godey F, Grassi MM, Grassi GB, Laws S, Massarut S, Naccarato G, Natalicchio MI, Orefice S, Palmieri F, Perin T, Roncella M, Roncalli MG, Rulli A, Sidoni A, Tinterri C, Truglia MC, Sperduti I.
PMID: 28511715
J Exp Clin Cancer Res. 2017 May 16;36(1):69. doi: 10.1186/s13046-017-0540-2.

No abstract available.

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Di Filippo F, Di Filippo S, Ferrari AM, et al. Erratum to: Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase. J Exp Clin Cancer Res. 2017;36(1):69doi: 10.1186/s13046-017-0540-2.
Di Filippo, F., Di Filippo, S., Ferrari, A. M., Antonetti, R., Battaglia, A., Becherini, F., Bernet, L., Boldorini, R., Bouteille, C., Buglioni, S., Burelli, P., Cano, R., Canzonieri, V., Chiodera, P., Cirilli, A., Coppola, L., Drago, S., Di Tommaso, L., Fenaroli, P., Franchini, R., Gianatti, A., Giannarelli, D., Giardina, C., Godey, F., Grassi, M. M., Grassi, G. B., Laws, S., Massarut, S., Naccarato, G., Natalicchio, M. I., Orefice, S., Palmieri, F., Perin, T., Roncella, M., Roncalli, M. G., Rulli, A., Sidoni, A., Tinterri, C., Truglia, M. C., & Sperduti, I. (2017). Erratum to: Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase. Journal of experimental & clinical cancer research : CR, 36(1), 69. https://doi.org/10.1186/s13046-017-0540-2
Di Filippo, Franco, et al. "Erratum to: Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase." Journal of experimental & clinical cancer research : CR vol. 36,1 (2017): 69. doi: https://doi.org/10.1186/s13046-017-0540-2
Di Filippo F, Di Filippo S, Ferrari AM, Antonetti R, Battaglia A, Becherini F, Bernet L, Boldorini R, Bouteille C, Buglioni S, Burelli P, Cano R, Canzonieri V, Chiodera P, Cirilli A, Coppola L, Drago S, Di Tommaso L, Fenaroli P, Franchini R, Gianatti A, Giannarelli D, Giardina C, Godey F, Grassi MM, Grassi GB, Laws S, Massarut S, Naccarato G, Natalicchio MI, Orefice S, Palmieri F, Perin T, Roncella M, Roncalli MG, Rulli A, Sidoni A, Tinterri C, Truglia MC, Sperduti I. Erratum to: Elaboration of a nomogram to predict nonsentinel node status in breast cancer patients with positive sentinel node, intraoperatively assessed with one step nucleic amplification: Retrospective and validation phase. J Exp Clin Cancer Res. 2017 May 16;36(1):69. doi: 10.1186/s13046-017-0540-2. PMID: 28511715; PMCID: PMC5434518.
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Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Morales C, de Luis D, de Arellano AR, Ferrario MG, Lizán L.
PMID: 26589521
Diabetes Ther. 2015 Dec;6(4):593-610. doi: 10.1007/s13300-015-0143-x. Epub 2015 Nov 20.

INTRODUCTION: An ExcelMETHODS: Clinical benefits included the non-severe hypoglycemia rate for T1DM and T2DM, and weight change for T2DM. Three scenarios were included with different hypoglycemia rates estimated on the basis of clinical trials and observational studies. Costs, estimated...

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Morales C, de Luis D, de Arellano AR, et al. Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain. Diabetes Ther. 2015;6(4):593-610doi: 10.1007/s13300-015-0143-x.
Morales, C., de Luis, D., de Arellano, A. R., Ferrario, M. G., & Lizán, L. (2015). Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain. Diabetes therapy : research, treatment and education of diabetes and related disorders, 6(4), 593-610. https://doi.org/10.1007/s13300-015-0143-x
Morales, Cristóbal, et al. "Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain." Diabetes therapy : research, treatment and education of diabetes and related disorders vol. 6,4 (2015): 593-610. doi: https://doi.org/10.1007/s13300-015-0143-x
Morales C, de Luis D, de Arellano AR, Ferrario MG, Lizán L. Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain. Diabetes Ther. 2015 Dec;6(4):593-610. doi: 10.1007/s13300-015-0143-x. Epub 2015 Nov 20. PMID: 26589521; PMCID: PMC4674462.
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Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats.

Cardiovascular endocrinology

Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI.
PMID: 23795309
Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159.

OBJECTIVES: Long-term systemic blockade of the renin-angiotensin system (RAS) with either an angiotensin (Ang) II type 1 receptor antagonist or an angiotensin-converting enzyme inhibitor attenuates age-related cardiac remodeling and oxidative damage, and improves myocardial relaxation. However, the role of...

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Groban L, Wang H, Machado FS, et al. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012;1(3):49-58doi: 10.1097/XCE.0b013e32835a2159.
Groban, L., Wang, H., Machado, F. S., Trask, A. J., Kritchevsky, S. B., Ferrario, C. M., & Diz, D. I. (2012). Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovascular endocrinology, 1(3), 49-58. https://doi.org/10.1097/XCE.0b013e32835a2159
Groban, Leanne, et al. "Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats." Cardiovascular endocrinology vol. 1,3 (2012): 49-58. doi: https://doi.org/10.1097/XCE.0b013e32835a2159
Groban L, Wang H, Machado FS, Trask AJ, Kritchevsky SB, Ferrario CM, Diz DI. Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats. Cardiovasc Endocrinol. 2012 Sep 01;1(3):49-58. doi: 10.1097/XCE.0b013e32835a2159. PMID: 23795309; PMCID: PMC3685869.
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Ocean acidification and responses to predators: can sensory redundancy reduce the apparent impacts of elevated CO2 on fish?.

Ecology and evolution

Lönnstedt OM, Munday PL, McCormick MI, Ferrari MC, Chivers DP.
PMID: 24223291
Ecol Evol. 2013 Sep;3(10):3565-75. doi: 10.1002/ece3.684. Epub 2013 Sep 02.

Carbon dioxide (CO2) levels in the atmosphere and surface ocean are rising at an unprecedented rate due to sustained and accelerating anthropogenic CO2 emissions. Previous studies have documented that exposure to elevated CO2 causes impaired antipredator behavior by coral...

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Lönnstedt OM, Munday PL, McCormick MI, et al. Ocean acidification and responses to predators: can sensory redundancy reduce the apparent impacts of elevated CO2 on fish?. Ecol Evol. 2013;3(10):3565-75doi: 10.1002/ece3.684.
Lönnstedt, O. M., Munday, P. L., McCormick, M. I., Ferrari, M. C., & Chivers, D. P. (2013). Ocean acidification and responses to predators: can sensory redundancy reduce the apparent impacts of elevated CO2 on fish?. Ecology and evolution, 3(10), 3565-75. https://doi.org/10.1002/ece3.684
Lönnstedt, Oona M, et al. "Ocean acidification and responses to predators: can sensory redundancy reduce the apparent impacts of elevated CO2 on fish?." Ecology and evolution vol. 3,10 (2013): 3565-75. doi: https://doi.org/10.1002/ece3.684
Lönnstedt OM, Munday PL, McCormick MI, Ferrari MC, Chivers DP. Ocean acidification and responses to predators: can sensory redundancy reduce the apparent impacts of elevated CO2 on fish?. Ecol Evol. 2013 Sep;3(10):3565-75. doi: 10.1002/ece3.684. Epub 2013 Sep 02. PMID: 24223291; PMCID: PMC3797500.
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Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions.

Scientific reports

Pompili R, Anania MP, Bisesto F, Botton M, Castellano M, Chiadroni E, Cianchi A, Curcio A, Ferrario M, Galletti M, Henis Z, Petrarca M, Schleifer E, Zigler A.
PMID: 27713541
Sci Rep. 2016 Oct 07;6:35000. doi: 10.1038/srep35000.

Highly energetic electrons are generated at the early phases of the interaction of short-pulse high-intensity lasers with solid targets. These escaping particles are identified as the essential core of picosecond-scale phenomena such as laser-based acceleration, surface manipulation, generation of...

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Pompili R, Anania MP, Bisesto F, et al. Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions. Sci Rep. 2016;6:35000doi: 10.1038/srep35000.
Pompili, R., Anania, M. P., Bisesto, F., Botton, M., Castellano, M., Chiadroni, E., Cianchi, A., Curcio, A., Ferrario, M., Galletti, M., Henis, Z., Petrarca, M., Schleifer, E., & Zigler, A. (2016). Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions. Scientific reports, 635000. https://doi.org/10.1038/srep35000
Pompili, R, et al. "Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions." Scientific reports vol. 6 (2016): 35000. doi: https://doi.org/10.1038/srep35000
Pompili R, Anania MP, Bisesto F, Botton M, Castellano M, Chiadroni E, Cianchi A, Curcio A, Ferrario M, Galletti M, Henis Z, Petrarca M, Schleifer E, Zigler A. Femtosecond dynamics of energetic electrons in high intensity laser-matter interactions. Sci Rep. 2016 Oct 07;6:35000. doi: 10.1038/srep35000. PMID: 27713541; PMCID: PMC5054520.
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Measurement of Workability of Fresh Concrete Using a Mixing Truck.

Journal of research of the National Institute of Standards and Technology

Amziane S, Ferraris CF, Koehler EP.
PMID: 27308103
J Res Natl Inst Stand Technol. 2005 Feb 01;110(1):55-66. doi: 10.6028/jres.110.006. Print 2005.

The main objective of this study is to evaluate the workability of fresh portland cement concrete while it is still in the mixing truck by determining fundamental rheological parameters (plastic viscosity and yield stress). Nine concrete mixtures with different...

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Amziane S, Ferraris CF, Koehler EP. Measurement of Workability of Fresh Concrete Using a Mixing Truck. J Res Natl Inst Stand Technol. 2005;110(1):55-66doi: 10.6028/jres.110.006.
Amziane, S., Ferraris, C. F., & Koehler, E. P. (2005). Measurement of Workability of Fresh Concrete Using a Mixing Truck. Journal of research of the National Institute of Standards and Technology, 110(1), 55-66. https://doi.org/10.6028/jres.110.006
Amziane, Sofiane, et al. "Measurement of Workability of Fresh Concrete Using a Mixing Truck." Journal of research of the National Institute of Standards and Technology vol. 110,1 (2005): 55-66. doi: https://doi.org/10.6028/jres.110.006
Amziane S, Ferraris CF, Koehler EP. Measurement of Workability of Fresh Concrete Using a Mixing Truck. J Res Natl Inst Stand Technol. 2005 Feb 01;110(1):55-66. doi: 10.6028/jres.110.006. Print 2005. PMID: 27308103; PMCID: PMC4849560.
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Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan.

Integrated blood pressure control

Varagic J, Punzi H, Ferrario CM.
PMID: 25473311
Integr Blood Press Control. 2014 Nov 26;7:61-70. doi: 10.2147/IBPC.S50954. eCollection 2014.

Despite significant advances in pharmacologic approaches to treat hypertension during the last decades, hypertension- and hypertension-related organ damage are still a high health and economic burden because a large proportion of patients with hypertension do not achieve optimal blood...

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Varagic J, Punzi H, Ferrario CM. Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan. Integr Blood Press Control. 2014;7:61-70doi: 10.2147/IBPC.S50954.
Varagic, J., Punzi, H., & Ferrario, C. M. (2014). Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan. Integrated blood pressure control, 761-70. https://doi.org/10.2147/IBPC.S50954
Varagic, Jasmina, et al. "Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan." Integrated blood pressure control vol. 7 (2014): 61-70. doi: https://doi.org/10.2147/IBPC.S50954
Varagic J, Punzi H, Ferrario CM. Clinical utility of fixed-dose combinations in hypertension: evidence for the potential of nebivolol/valsartan. Integr Blood Press Control. 2014 Nov 26;7:61-70. doi: 10.2147/IBPC.S50954. eCollection 2014. PMID: 25473311; PMCID: PMC4251532.
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Probabilistic Derivation of Spatiotemporal Correlation Functions in the Hydrodynamic Limit.

The journal of physical chemistry. B

Ciccotti G, Bonella S, Ferrario M, Pierleoni C.
PMID: 26720838
J Phys Chem B. 2016 Mar 03;120(8):1996-2000. doi: 10.1021/acs.jpcb.5b10066. Epub 2016 Jan 19.

In this paper, we use probability theory to prove in suitable conditions the equivalence of equilibrium time correlation functions of microscopic density fields with the time correlation functions of local macroscopic density fields evolved by hydrodynamics in (approximate) phenomenological...

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Ciccotti G, Bonella S, Ferrario M, et al. Probabilistic Derivation of Spatiotemporal Correlation Functions in the Hydrodynamic Limit. J Phys Chem B. 2016;120(8):1996-2000doi: 10.1021/acs.jpcb.5b10066.
Ciccotti, G., Bonella, S., Ferrario, M., & Pierleoni, C. (2016). Probabilistic Derivation of Spatiotemporal Correlation Functions in the Hydrodynamic Limit. The journal of physical chemistry. B, 120(8), 1996-2000. https://doi.org/10.1021/acs.jpcb.5b10066
Ciccotti, Giovanni, et al. "Probabilistic Derivation of Spatiotemporal Correlation Functions in the Hydrodynamic Limit." The journal of physical chemistry. B vol. 120,8 (2016): 1996-2000. doi: https://doi.org/10.1021/acs.jpcb.5b10066
Ciccotti G, Bonella S, Ferrario M, Pierleoni C. Probabilistic Derivation of Spatiotemporal Correlation Functions in the Hydrodynamic Limit. J Phys Chem B. 2016 Mar 03;120(8):1996-2000. doi: 10.1021/acs.jpcb.5b10066. Epub 2016 Jan 19. PMID: 26720838.
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Short-term variations in the occurrence of heavy metals in Antarctic snow from Coats Land since the 1920s.

The Science of the total environment

Planchon FA, Boutron CE, Barbante C, Cozzi G, Gaspari V, Wolff EW, Ferrari CP, Cescon P.
PMID: 12685477
Sci Total Environ. 2002 Dec 02;300(1):129-42. doi: 10.1016/s0048-9697(02)00277-2.

Short-term variations in heavy metals concentrations in Antarctic snow have been investigated by analysing 13 metals (Al, V, Cr, Mn, Co, Cu, Zn, Ag, Cd, Ba, Pb, Bi and U) in a series of ultraclean samples collected from two...

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Planchon FA, Boutron CE, Barbante C, et al. Short-term variations in the occurrence of heavy metals in Antarctic snow from Coats Land since the 1920s. Sci Total Environ. 2002;300(1):129-42doi: 10.1016/s0048-9697(02)00277-2.
Planchon, F. A., Boutron, C. E., Barbante, C., Cozzi, G., Gaspari, V., Wolff, E. W., Ferrari, C. P., & Cescon, P. (2002). Short-term variations in the occurrence of heavy metals in Antarctic snow from Coats Land since the 1920s. The Science of the total environment, 300(1), 129-42. https://doi.org/10.1016/s0048-9697(02)00277-2
Planchon, Frédéric A M, et al. "Short-term variations in the occurrence of heavy metals in Antarctic snow from Coats Land since the 1920s." The Science of the total environment vol. 300,1 (2002): 129-42. doi: https://doi.org/10.1016/s0048-9697(02)00277-2
Planchon FA, Boutron CE, Barbante C, Cozzi G, Gaspari V, Wolff EW, Ferrari CP, Cescon P. Short-term variations in the occurrence of heavy metals in Antarctic snow from Coats Land since the 1920s. Sci Total Environ. 2002 Dec 02;300(1):129-42. doi: 10.1016/s0048-9697(02)00277-2. PMID: 12685477.
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Identification of defect sites on MgO(100) thin films by decoration with Pd atoms and studying CO adsorption properties.

Journal of the American Chemical Society

Abbet S, Riedo E, Brune H, Heiz U, Ferrari AM, Giordano L, Pacchioni G.
PMID: 11414852
J Am Chem Soc. 2001 Jun 27;123(25):6172-8. doi: 10.1021/ja0157651.

CO adsorption on Pd atoms deposited on MgO(100) thin films has been studied by means of thermal desorption (TDS) and Fourier transform infrared (FTIR) spectroscopies. CO desorbs from the adsorbed Pd atoms at a temperature of about 250 K,...

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Abbet S, Riedo E, Brune H, et al. Identification of defect sites on MgO(100) thin films by decoration with Pd atoms and studying CO adsorption properties. J Am Chem Soc. 2001;123(25):6172-8doi: 10.1021/ja0157651.
Abbet, S., Riedo, E., Brune, H., Heiz, U., Ferrari, A. M., Giordano, L., & Pacchioni, G. (2001). Identification of defect sites on MgO(100) thin films by decoration with Pd atoms and studying CO adsorption properties. Journal of the American Chemical Society, 123(25), 6172-8. https://doi.org/10.1021/ja0157651
Abbet, S, et al. "Identification of defect sites on MgO(100) thin films by decoration with Pd atoms and studying CO adsorption properties." Journal of the American Chemical Society vol. 123,25 (2001): 6172-8. doi: https://doi.org/10.1021/ja0157651
Abbet S, Riedo E, Brune H, Heiz U, Ferrari AM, Giordano L, Pacchioni G. Identification of defect sites on MgO(100) thin films by decoration with Pd atoms and studying CO adsorption properties. J Am Chem Soc. 2001 Jun 27;123(25):6172-8. doi: 10.1021/ja0157651. PMID: 11414852.
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First investigation of an original device dedicated to the determination of gaseous mercury in interstitial air in snow.

Analytical and bioanalytical chemistry

Dommergue A, Ferrari CP, Boutron CF.
PMID: 12520445
Anal Bioanal Chem. 2003 Jan;375(1):106-11. doi: 10.1007/s00216-002-1643-x. Epub 2002 Nov 14.

The GAMAS (gaseous mercury in interstitial air in snow) instrument developed in our laboratory is a new device devoted to sampling and determination of gaseous mercury concentration in interstitial air in snow. Sampling probes inserted in the snowpack, coupled...

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Dommergue A, Ferrari CP, Boutron CF. First investigation of an original device dedicated to the determination of gaseous mercury in interstitial air in snow. Anal Bioanal Chem. 2002;375(1):106-11doi: 10.1007/s00216-002-1643-x.
Dommergue, A., Ferrari, C. P., & Boutron, C. F. (2003). First investigation of an original device dedicated to the determination of gaseous mercury in interstitial air in snow. Analytical and bioanalytical chemistry, 375(1), 106-11. https://doi.org/10.1007/s00216-002-1643-x
Dommergue, Aurélien, et al. "First investigation of an original device dedicated to the determination of gaseous mercury in interstitial air in snow." Analytical and bioanalytical chemistry vol. 375,1 (2003): 106-11. doi: https://doi.org/10.1007/s00216-002-1643-x
Dommergue A, Ferrari CP, Boutron CF. First investigation of an original device dedicated to the determination of gaseous mercury in interstitial air in snow. Anal Bioanal Chem. 2003 Jan;375(1):106-11. doi: 10.1007/s00216-002-1643-x. Epub 2002 Nov 14. PMID: 12520445.
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