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Showing 1 to 12 of 90 entries
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Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

Caimmi D, Baiz N, Tanno LK, Demoly P, Arnavielhe S, Murray R, Bedbrook A, Bergmann KC, De Vries G, Fokkens WJ, Fonseca J, Haahtela T, Keil T, Kuna P, Mullol J, Papadopoulos N, Passalacqua G, Samolinski B, Tomazic PV, Valiulis A, van Eerd M, Wickman M, Annesi-Maesano I, Bousquet J.
PMID: 28886234
Clin Exp Allergy. 2017 Dec;47(12):1526-1533. doi: 10.1111/cea.13025. Epub 2017 Oct 11.

BACKGROUND: Visual Analogue Scale (VAS) is a validated tool to assess control in allergic rhinitis patients.OBJECTIVE: The aim of this study was to validate the use of VAS in the MASK-rhinitis (MACVIA-ARIA Sentinel NetworK for allergic rhinitis) app (Allergy...

Characterisation of interleukin-10 expression on different vascular structures in allergic nasal mucosa.

Clinical and translational allergy

Muller B, van Egmond D, de Groot EJ, Fokkens WJ, van Drunen CM.
PMID: 24405811
Clin Transl Allergy. 2014 Jan 10;4(1):2. doi: 10.1186/2045-7022-4-2.

BACKGROUND: Interleukin-10 (IL-10) is a negative regulator of immune responses and was previously shown to be expressed by human nasal endothelial cells, while the adhesion molecule MECA-79 plays a role in trans-endothelial migration of immune competent cells. In this...

A common language to assess allergic rhinitis control: results from a survey conducted during EAACI 2013 Congress.

Clinical and translational allergy

Hellings PW, Muraro A, Fokkens W, Mullol J, Bachert C, Canonica GW, Price D, Papadopoulos N, Scadding G, Rasp G, Demoly P, Murray R, Bousquet J.
PMID: 26509001
Clin Transl Allergy. 2015 Oct 27;5:36. doi: 10.1186/s13601-015-0080-9. eCollection 2015.

BACKGROUND: The concept of control is gaining importance in the field of allergic rhinitis (AR), with a visual analogue scale (VAS) score being a validated, easy and attractive tool to evaluate AR symptom control. The doctors' perception of a...

The role of distonic ions in the formation of CH3NH 3 (+) and (CH 3) 2NH 2 (+) from the molecular ions of octopamine and synephrine.

Journal of the American Society for Mass Spectrometry

Cardoso AM, Ferrer-Correia AJ, Fokkens RH, Nibbering NM.
PMID: 24248617
J Am Soc Mass Spectrom. 1990 Feb;1(1):104-6. doi: 10.1016/1044-0305(90)80012-C.

It is shown by mass-analyzed ion kinetic energy spectrometry that the metastably decomposing molecular ions of octopamine (p-HOC6H4CH(OH)CH2NH2) and synephrine (p-HOC6H4CH(OH)CH2NHCH3) yield only protonated methylamine and dimethylamine, respectively, as product ions. From deuterium labeling and variation of the internal...

Nanostructures via noncovalent synthesis: 144 hydrogen bonds bring together 27 components.

The Journal of organic chemistry

Paraschiv V, Crego-Calamas M, Fokkens RH, Padberg CJ, Timmerman P, Reinhoudt DN.
PMID: 11735506
J Org Chem. 2001 Dec 14;66(25):8297-301. doi: 10.1021/jo0105742.

This paper describes the spontaneous and reversible assembly of approximately 20 kDa synthetic hydrogen-bonded assemblies via the formation of 144 cooperative hydrogen bonds. These nanostructures ( approximately 3.0 x 5.5 nm), consisting of 27 different components, have been carefully...

Diesel engine exhaust initiates a sequence of pulmonary and cardiovascular effects in rats.

Journal of toxicology

Kooter IM, Gerlofs-Nijland ME, Boere AJ, Leseman DL, Fokkens PH, Spronk HM, Frederix K, Ten Cate H, Knaapen AM, Vreman HJ, Cassee FR.
PMID: 21052503
J Toxicol. 2010;2010:206057. doi: 10.1155/2010/206057. Epub 2010 Oct 31.

This study was designed to determine the sequence of events leading to cardiopulmonary effects following acute inhalation of diesel engine exhaust in rats. Rats were exposed for 2 h to diesel engine exhaust (1.9 mg/m(3)), and biological parameters related...

The skin prick test - European standards.

Clinical and translational allergy

Heinzerling L, Mari A, Bergmann KC, Bresciani M, Burbach G, Darsow U, Durham S, Fokkens W, Gjomarkaj M, Haahtela T, Bom AT, Wöhrl S, Maibach H, Lockey R.
PMID: 23369181
Clin Transl Allergy. 2013 Feb 01;3(1):3. doi: 10.1186/2045-7022-3-3.

Skin prick testing is an essential test procedure to confirm sensitization in IgE-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. This manuscript reviews the available evidence including Medline and Embase...

Diagnostic tools in Rhinology EAACI position paper.

Clinical and translational allergy

Scadding G, Hellings P, Alobid I, Bachert C, Fokkens W, van Wijk RG, Gevaert P, Guilemany J, Kalogjera L, Lund V, Mullol J, Passalacqua G, Toskala E, van Drunen C.
PMID: 22410181
Clin Transl Allergy. 2011 Jun 10;1(1):2. doi: 10.1186/2045-7022-1-2.

This EAACI Task Force document aims at providing the readers with a comprehensive and complete overview of the currently available tools for diagnosis of nasal and sino-nasal disease. We have tried to logically order the different important issues related...

Ethical considerations for health professions education research matter.

Journal of professional nursing : official journal of the American Association of Colleges of Nursing

Schutte T, Fokkens J, Bertens R, Scherpbier A.
PMID: 34887044
J Prof Nurs. 2021 Nov-Dec;37(6):1205-1206. doi: 10.1016/j.profnurs.2021.08.005. Epub 2021 Aug 06.

No abstract available.

News from Rhinology Journal.

Rhinology

Fokkens WJ.
PMID: 34331531
Rhinology. 2021 Aug 01;59(4):329. doi: 10.4193/Rhin21.804.

No abstract available.

Systematic analysis of PINK1 variants of unknown significance shows intact mitophagy function for most variants.

NPJ Parkinson's disease

Ma KY, Fokkens MR, van Laar T, Verbeek DS.
PMID: 34893635
NPJ Parkinsons Dis. 2021 Dec 10;7(1):113. doi: 10.1038/s41531-021-00258-8.

Pathogenic variants in PINK1 cause early-onset Parkinson's disease. Although many PINK1 variants have been reported, the clinical significance is uncertain for the majority of them. To gain insights into the consequences of PINK1 missense variants in a systematic manner,...

Systematic analysis of PINK1 variants of unknown significance shows intact mitophagy function for most variants.

NPJ Parkinson's disease

Ma KY, Fokkens MR, van Laar T, Verbeek DS.
PMID: 34893635
NPJ Parkinsons Dis. 2021 Dec 10;7(1):113. doi: 10.1038/s41531-021-00258-8.

Pathogenic variants in PINK1 cause early-onset Parkinson's disease. Although many PINK1 variants have been reported, the clinical significance is uncertain for the majority of them. To gain insights into the consequences of PINK1 missense variants in a systematic manner,...

Showing 1 to 12 of 90 entries