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Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with wiskott-Aldrich syndrome.

Frontiers in immunology

O'Connell AE, Volpi S, Dobbs K, Fiorini C, Tsitsikov E, de Boer H, Barlan IB, Despotovic JM, Espinosa-Rosales FJ, Hanson IC, Kanariou MG, Martínez-Beckerat R, Mayorga-Sirera A, Mejia-Carvajal C, Radwan N, Weiss AR, Pai SY, Lee YN, Notarangelo LD.
PMID: 25101082
Front Immunol. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340. eCollection 2014.

The Wiskott-Aldrich syndrome (WAS) is due to mutations of the WAS gene encoding for the cytoskeletal WAS protein, leading to abnormal downstream signaling from the T cell and B cell antigen receptors (TCR and BCR). We hypothesized that the...

Electronic and vibrational circular dichroism spectroscopies for the understanding of chiral organization in porphyrin aggregates.

Chemical communications (Cambridge, England)

Nieto-Ortega B, Ramírez FJ, Amabilino DB, Linares M, Beljonne D, López Navarrete JT, Casado J.
PMID: 22872159
Chem Commun (Camb). 2012 Sep 21;48(73):9147-9. doi: 10.1039/c2cc34374f. Epub 2012 Aug 08.

Dichroic optical spectroscopies and theoretical modelling have been used to describe the structure of aggregates of porphyrins in their gels in terms of: (i) the formation of helicoidal structures, (ii) the sign of the handedness, (iii) their extent and...

Trends in adult asthma hospitalization: gender-age effect.

Multidisciplinary respiratory medicine

Gonzalez-Barcala FJ, Aboal J, Valdes L, Carreira JM, Alvarez-Dobaño JM, Puga A, Garcia-Sanz MT, Takkouche B.
PMID: 22958944
Multidiscip Respir Med. 2011 Apr 30;6(2):82-6. doi: 10.1186/2049-6958-6-2-82.

BACKGROUND: Hospital admissions due to asthma are a reliable source of information on the morbidity of the disease which, after the increase observed in the last quarter of the last century, shows a declining trend in the last few...

Development and characterization of 10 microsatellite loci in the giant cardon cactus, Pachycereus pringlei (Cactaceae).

Applications in plant sciences

Gutiérrez Flores C, Lozano Garza OA, León de la Luz JL, García de León FJ.
PMID: 25202601
Appl Plant Sci. 2014 Jan 29;2(2). doi: 10.3732/apps.1300066. eCollection 2014 Feb.

PREMISE OF THE STUDY: Microsatellite primers were developed for the cardon, a giant columnar cactus (Pachycereus pringlei) of the Sonoran Desert, to investigate intraspecific genetic patterns of diversity and population structure. •METHODS AND RESULTS: Using 454 GS-FLX technology and...

Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the Gram-Positive Bacterial Pathogen .

Frontiers in microbiology

Querol-García J, Fernández FJ, Marin AV, Gómez S, Fullà D, Melchor-Tafur C, Franco-Hidalgo V, Albertí S, Juanhuix J, Rodríguez de Córdoba S, Regueiro JR, Vega MC.
PMID: 28443070
Front Microbiol. 2017 Apr 10;8:541. doi: 10.3389/fmicb.2017.00541. eCollection 2017.

The Gram-positive anaerobic human pathogenic bacterium

Role of Ivabradine in the Treatment of Heart Failure: Comments on the ESC 2016 Guidelines.

Revista espanola de cardiologia (English ed.)

Hidalgo FJ, Anguita M.
PMID: 28456506
Rev Esp Cardiol (Engl Ed). 2017 Jul;70(7):612-613. doi: 10.1016/j.rec.2016.12.045. Epub 2017 Apr 26.

No abstract available.

Forearm Flexor Muscles in Children with Cerebral Palsy Are Weak, Thin and Stiff.

Frontiers in computational neuroscience

von Walden F, Jalaleddini K, Evertsson B, Friberg J, Valero-Cuevas FJ, Pontén E.
PMID: 28487645
Front Comput Neurosci. 2017 Apr 25;11:30. doi: 10.3389/fncom.2017.00030. eCollection 2017.

Children with cerebral palsy (CP) often develop reduced passive range of motion with age. The determining factor underlying this process is believed to be progressive development of contracture in skeletal muscle that likely changes the biomechanics of the joints....

GRASSP: a spectrograph for the study of transient luminous events.

Applied optics

Passas M, Sánchez J, Sánchez-Blanco E, Luque A, Gordillo-Vázquez FJ.
PMID: 27534491
Appl Opt. 2016 Aug 10;55(23):6436-42. doi: 10.1364/AO.55.006436.

We present the main parameters, design features, and optical characterization of the Granada Sprite Spectrograph and Polarimeter (GRASSP), a ground-based spectrographic system intended for the analysis of the spectroscopic signature of transient luminous events (TLEs) occurring in the mesosphere...

α-Tocopheryl succinate-based amphiphilic block copolymers obtained by RAFT and their nanoparticles for the treatment of cancer.

Polymer chemistry

Palao-Suay R, Aguilar MR, Parra-Ruiz FJ, Maji S, Hoogenboom R, Rohner NA, Thomas SN, Román JS.
PMID: 27004068
Polym Chem. 2016 Jan 28;7(4):838-850. doi: 10.1039/C5PY01811K. Epub 2015 Nov 27.

α-Tocopheryl succinate (α-TOS) is a well-known mitochondrially targeted anticancer compound. However, the major factor limiting the use of α-TOS is its low solubility in physiological media. To overcome this problem, the aim of this work is the preparation of...

Beta Band Corticomuscular Drive Reflects Muscle Coordination Strategies.

Frontiers in computational neuroscience

Reyes A, Laine CM, Kutch JJ, Valero-Cuevas FJ.
PMID: 28420975
Front Comput Neurosci. 2017 Apr 04;11:17. doi: 10.3389/fncom.2017.00017. eCollection 2017.

During force production, hand muscle activity is known to be coherent with activity in primary motor cortex, specifically in the beta-band (15-30 Hz) frequency range. It is not clear, however, if this coherence reflects the control strategy selected by...

Effects of sewage effluents and seasonal changes on the metabolism of three Atlantic rivers.

The Science of the total environment

Rodríguez-Castillo T, Barquín J, Álvarez-Cabria M, Peñas FJ, Álvarez C.
PMID: 28511356
Sci Total Environ. 2017 Dec 01;599:1108-1118. doi: 10.1016/j.scitotenv.2017.05.067. Epub 2017 May 12.

Sewage inputs on fluvial ecosystems affect benthic communities and alter trophic networks resulting in changes on river functioning. Functional indicators (e.g. river metabolism) have been proposed as a valuable tool to evaluate ecosystem impairment. In the present study we...

Antihyperalgesic Effect of Hesperidin Improves with Diosmin in Experimental Neuropathic Pain.

BioMed research international

Carballo-Villalobos AI, González-Trujano ME, Pellicer F, López-Muñoz FJ.
PMID: 27672659
Biomed Res Int. 2016;2016:8263463. doi: 10.1155/2016/8263463. Epub 2016 Sep 08.

Neuropathic pain is caused by a primary lesion, dysfunction, or transitory perturbation in the peripheral or central nervous system. In this study, we investigated the hesperidin antihyperalgesic effects alone or combined with diosmin in a model of neuropathic pain...

Showing 1 to 12 of 2880 entries