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Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy.

Scientific reports

Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D'Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M.
PMID: 27677466
Sci Rep. 2016 Sep 28;6:34325. doi: 10.1038/srep34325.

Dysfunction of the inwardly-rectifying potassium channels Kir4.1 (KCNJ10) represents a pathogenic mechanism contributing to Autism-Epilepsy comorbidity. To define the role of Kir4.1 variants in the disorder, we sequenced KCNJ10 in a sample of affected individuals, and performed genotype-phenotype correlations....

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Sicca F, Ambrosini E, Marchese M, et al. Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. Sci Rep. 2016;6:34325doi: 10.1038/srep34325.
Sicca, F., Ambrosini, E., Marchese, M., Sforna, L., Servettini, I., Valvo, G., Brignone, M. S., Lanciotti, A., Moro, F., Grottesi, A., Catacuzzeno, L., Baldini, S., Hasan, S., D'Adamo, M. C., Franciolini, F., Molinari, P., Santorelli, F. M., & Pessia, M. (2016). Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. Scientific reports, 634325. https://doi.org/10.1038/srep34325
Sicca, Federico, et al. "Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy." Scientific reports vol. 6 (2016): 34325. doi: https://doi.org/10.1038/srep34325
Sicca F, Ambrosini E, Marchese M, Sforna L, Servettini I, Valvo G, Brignone MS, Lanciotti A, Moro F, Grottesi A, Catacuzzeno L, Baldini S, Hasan S, D'Adamo MC, Franciolini F, Molinari P, Santorelli FM, Pessia M. Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. Sci Rep. 2016 Sep 28;6:34325. doi: 10.1038/srep34325. PMID: 27677466; PMCID: PMC5039625.
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Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration.

Frontiers in cellular neuroscience

Catacuzzeno L, Caramia M, Sforna L, Belia S, Guglielmi L, D'Adamo MC, Pessia M, Franciolini F.
PMID: 25941475
Front Cell Neurosci. 2015 Apr 20;9:152. doi: 10.3389/fncel.2015.00152. eCollection 2015.

Glioblastoma (GBM) is the most common and aggressive primary brain tumor, and is notable for spreading so effectively through the brain parenchyma to make complete surgical resection virtually impossible, and prospect of life dismal. Several ion channels have been...

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Catacuzzeno L, Caramia M, Sforna L, et al. Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration. Front Cell Neurosci. 2015;9:152doi: 10.3389/fncel.2015.00152.
Catacuzzeno, L., Caramia, M., Sforna, L., Belia, S., Guglielmi, L., D'Adamo, M. C., Pessia, M., & Franciolini, F. (2015). Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration. Frontiers in cellular neuroscience, 9152. https://doi.org/10.3389/fncel.2015.00152
Catacuzzeno, Luigi, et al. "Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration." Frontiers in cellular neuroscience vol. 9 (2015): 152. doi: https://doi.org/10.3389/fncel.2015.00152
Catacuzzeno L, Caramia M, Sforna L, Belia S, Guglielmi L, D'Adamo MC, Pessia M, Franciolini F. Reconciling the discrepancies on the involvement of large-conductance Ca(2+)-activated K channels in glioblastoma cell migration. Front Cell Neurosci. 2015 Apr 20;9:152. doi: 10.3389/fncel.2015.00152. eCollection 2015. PMID: 25941475; PMCID: PMC4403502.
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A Pulmonary Rehabilitation Decisional Score to Define Priority Access for COPD Patients.

Rehabilitation research and practice

Vitacca M, Comini L, Barbisoni M, Francolini G, Paneroni M, Ramponi JP.
PMID: 28239495
Rehabil Res Pract. 2017;2017:5710676. doi: 10.1155/2017/5710676. Epub 2017 Jan 23.

This retrospective study aimed to evaluate, through an ad hoc 17-item tool, the Pulmonary Rehabilitation Decisional Score (PRDS), the priority access to PR prescription by respiratory specialists. The PRDS, scoring functional, clinical, disability, frailty, and participation parameters from 0...

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Vitacca M, Comini L, Barbisoni M, et al. A Pulmonary Rehabilitation Decisional Score to Define Priority Access for COPD Patients. Rehabil Res Pract. 2017;2017:5710676doi: 10.1155/2017/5710676.
Vitacca, M., Comini, L., Barbisoni, M., Francolini, G., Paneroni, M., & Ramponi, J. P. (2017). A Pulmonary Rehabilitation Decisional Score to Define Priority Access for COPD Patients. Rehabilitation research and practice, 20175710676. https://doi.org/10.1155/2017/5710676
Vitacca, Michele, et al. "A Pulmonary Rehabilitation Decisional Score to Define Priority Access for COPD Patients." Rehabilitation research and practice vol. 2017 (2017): 5710676. doi: https://doi.org/10.1155/2017/5710676
Vitacca M, Comini L, Barbisoni M, Francolini G, Paneroni M, Ramponi JP. A Pulmonary Rehabilitation Decisional Score to Define Priority Access for COPD Patients. Rehabil Res Pract. 2017;2017:5710676. doi: 10.1155/2017/5710676. Epub 2017 Jan 23. PMID: 28239495; PMCID: PMC5292400.
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Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder.

Frontiers in cellular neuroscience

Guglielmi L, Servettini I, Caramia M, Catacuzzeno L, Franciolini F, D'Adamo MC, Pessia M.
PMID: 25784856
Front Cell Neurosci. 2015 Mar 02;9:34. doi: 10.3389/fncel.2015.00034. eCollection 2015.

Autism spectrum disorders (ASDs) are characterized by impaired ability to properly implement environmental stimuli that are essential to achieve a state of social and cultural exchange. Indeed, the main features of ASD are impairments of interpersonal relationships, verbal and...

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Guglielmi L, Servettini I, Caramia M, et al. Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder. Front Cell Neurosci. 2015;9:34doi: 10.3389/fncel.2015.00034.
Guglielmi, L., Servettini, I., Caramia, M., Catacuzzeno, L., Franciolini, F., D'Adamo, M. C., & Pessia, M. (2015). Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder. Frontiers in cellular neuroscience, 934. https://doi.org/10.3389/fncel.2015.00034
Guglielmi, Luca, et al. "Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder." Frontiers in cellular neuroscience vol. 9 (2015): 34. doi: https://doi.org/10.3389/fncel.2015.00034
Guglielmi L, Servettini I, Caramia M, Catacuzzeno L, Franciolini F, D'Adamo MC, Pessia M. Update on the implication of potassium channels in autism: K(+) channelautism spectrum disorder. Front Cell Neurosci. 2015 Mar 02;9:34. doi: 10.3389/fncel.2015.00034. eCollection 2015. PMID: 25784856; PMCID: PMC4345917.
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Effect of paradoxical sleep deprivation on dna synthesis in fetal rat brain.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

Grassi-Zucconi G, Belia S, Franciolini F, Menichini E, Giuditta A.
PMID: 24874399
Int J Dev Neurosci. 1984;2(6):585-90. doi: 10.1016/0736-5748(84)90036-4.

We have investigated the effect of PS-D induced in gestating rats by treatment with clomipramine or with the platform technique on the process of DNA synthesis taking place in fetal organs. This parameter was taken as a biochemical index...

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Grassi-Zucconi G, Belia S, Franciolini F, et al. Effect of paradoxical sleep deprivation on dna synthesis in fetal rat brain. Int J Dev Neurosci. 1984;2(6):585-90doi: 10.1016/0736-5748(84)90036-4.
Grassi-Zucconi, G., Belia, S., Franciolini, F., Menichini, E., & Giuditta, A. (1984). Effect of paradoxical sleep deprivation on dna synthesis in fetal rat brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2(6), 585-90. https://doi.org/10.1016/0736-5748(84)90036-4
Grassi-Zucconi, G, et al. "Effect of paradoxical sleep deprivation on dna synthesis in fetal rat brain." International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience vol. 2,6 (1984): 585-90. doi: https://doi.org/10.1016/0736-5748(84)90036-4
Grassi-Zucconi G, Belia S, Franciolini F, Menichini E, Giuditta A. Effect of paradoxical sleep deprivation on dna synthesis in fetal rat brain. Int J Dev Neurosci. 1984;2(6):585-90. doi: 10.1016/0736-5748(84)90036-4. PMID: 24874399.
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Indole Alkaloids from Quassia amara.

Planta medica

Barbetti P, Grandolini G, Fardella G, Chiappini I.
PMID: 17269024
Planta Med. 1987 Jun;53(3):289-90. doi: 10.1055/s-2006-962709.

Three beta-carboline alkaloids have been isolated for the first time from the wood of QUASSIA AMARA L. (Simarubaceae) and their structures were determined to be 1-vinyl-4,8-dimethoxy-beta-carboline ( 1), 1-methoxycarbonyl-beta-carboline ( 2), and 3-methylcantin-2,6-dione ( 3) by spectral and chemical...

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Barbetti P, Grandolini G, Fardella G, et al. Indole Alkaloids from Quassia amara. Planta Med. 1987;53(3):289-90doi: 10.1055/s-2006-962709.
Barbetti, P., Grandolini, G., Fardella, G., & Chiappini, I. (1987). Indole Alkaloids from Quassia amara. Planta medica, 53(3), 289-90. https://doi.org/10.1055/s-2006-962709
Barbetti, P, et al. "Indole Alkaloids from Quassia amara." Planta medica vol. 53,3 (1987): 289-90. doi: https://doi.org/10.1055/s-2006-962709
Barbetti P, Grandolini G, Fardella G, Chiappini I. Indole Alkaloids from Quassia amara. Planta Med. 1987 Jun;53(3):289-90. doi: 10.1055/s-2006-962709. PMID: 17269024.
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Lithium intercalation of phenyl-capped aniline dimers: a study by photoelectron spectroscopy and quantum chemical calculations.

The journal of physical chemistry. B

Kuritka I, Negri F, Brancolini G, Suess C, Salaneck WR, Friedlein R.
PMID: 16986899
J Phys Chem B. 2006 Sep 28;110(38):19023-30. doi: 10.1021/jp0575815.

Structural and electronic properties of pristine and lithium-intercalated, phenyl-capped aniline dimers as a model for the lithium-polyaniline system have been studied by photoelectron spectroscopy and quantum chemical calculations. It was found that the electronic structure of reduced and oxidized...

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Kuritka I, Negri F, Brancolini G, et al. Lithium intercalation of phenyl-capped aniline dimers: a study by photoelectron spectroscopy and quantum chemical calculations. J Phys Chem B. 2006;110(38):19023-30doi: 10.1021/jp0575815.
Kuritka, I., Negri, F., Brancolini, G., Suess, C., Salaneck, W. R., & Friedlein, R. (2006). Lithium intercalation of phenyl-capped aniline dimers: a study by photoelectron spectroscopy and quantum chemical calculations. The journal of physical chemistry. B, 110(38), 19023-30. https://doi.org/10.1021/jp0575815
Kuritka, Ivo, et al. "Lithium intercalation of phenyl-capped aniline dimers: a study by photoelectron spectroscopy and quantum chemical calculations." The journal of physical chemistry. B vol. 110,38 (2006): 19023-30. doi: https://doi.org/10.1021/jp0575815
Kuritka I, Negri F, Brancolini G, Suess C, Salaneck WR, Friedlein R. Lithium intercalation of phenyl-capped aniline dimers: a study by photoelectron spectroscopy and quantum chemical calculations. J Phys Chem B. 2006 Sep 28;110(38):19023-30. doi: 10.1021/jp0575815. PMID: 16986899.
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A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy.

Evidence-based complementary and alternative medicine : eCAM

Franconi G, Manni L, Schröder S, Marchetti P, Robinson N.
PMID: 23983788
Evid Based Complement Alternat Med. 2013;2013:516916. doi: 10.1155/2013/516916. Epub 2013 Jul 24.

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect that can be very disabling and can limit or delay the dose of chemotherapy that can be administered. Acupuncture may be effective for treating peripheral neuropathy. The aim of this...

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Franconi G, Manni L, Schröder S, et al. A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evid Based Complement Alternat Med. 2013;2013:516916doi: 10.1155/2013/516916.
Franconi, G., Manni, L., Schröder, S., Marchetti, P., & Robinson, N. (2013). A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evidence-based complementary and alternative medicine : eCAM, 2013516916. https://doi.org/10.1155/2013/516916
Franconi, Giovanna, et al. "A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy." Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 516916. doi: https://doi.org/10.1155/2013/516916
Franconi G, Manni L, Schröder S, Marchetti P, Robinson N. A systematic review of experimental and clinical acupuncture in chemotherapy-induced peripheral neuropathy. Evid Based Complement Alternat Med. 2013;2013:516916. doi: 10.1155/2013/516916. Epub 2013 Jul 24. PMID: 23983788; PMCID: PMC3741953.
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Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?.

Evidence-based complementary and alternative medicine : eCAM

Schröder S, Beckmann K, Franconi G, Meyer-Hamme G, Friedemann T, Greten HJ, Rostock M, Efferth T.
PMID: 23983777
Evid Based Complement Alternat Med. 2013;2013:423713. doi: 10.1155/2013/423713. Epub 2013 Jul 31.

Chemotherapy-induced neuropathy (CIPN) has a relevant impact on the quality of life of cancer patients. There are no curative conventional treatments, so further options have to be investigated. We conducted a systematic review in English and Chinese language databases...

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Schröder S, Beckmann K, Franconi G, et al. Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?. Evid Based Complement Alternat Med. 2013;2013:423713doi: 10.1155/2013/423713.
Schröder, S., Beckmann, K., Franconi, G., Meyer-Hamme, G., Friedemann, T., Greten, H. J., Rostock, M., & Efferth, T. (2013). Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?. Evidence-based complementary and alternative medicine : eCAM, 2013423713. https://doi.org/10.1155/2013/423713
Schröder, Sven, et al. "Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?." Evidence-based complementary and alternative medicine : eCAM vol. 2013 (2013): 423713. doi: https://doi.org/10.1155/2013/423713
Schröder S, Beckmann K, Franconi G, Meyer-Hamme G, Friedemann T, Greten HJ, Rostock M, Efferth T. Can medical herbs stimulate regeneration or neuroprotection and treat neuropathic pain in chemotherapy-induced peripheral neuropathy?. Evid Based Complement Alternat Med. 2013;2013:423713. doi: 10.1155/2013/423713. Epub 2013 Jul 31. PMID: 23983777; PMCID: PMC3747437.
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Corrigendum to "Role of Magnetic Resonance Imaging in the Preoperative Staging and Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive Ductolobular Carcinoma".

BioMed research international

Selvi V, Nori J, Meattini I, Francolini G, Morelli N, De Benedetto D, Bicchierai G, Di Naro F, Gill MK, Orzalesi L, Sanchez L, Susini T, Bianchi S, Livi L, Miele V.
PMID: 30258852
Biomed Res Int. 2018 Sep 06;2018:9056239. doi: 10.1155/2018/9056239. eCollection 2018.

[This corrects the article DOI: 10.1155/2018/1569060.].

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Selvi V, Nori J, Meattini I, et al. Corrigendum to "Role of Magnetic Resonance Imaging in the Preoperative Staging and Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive Ductolobular Carcinoma". Biomed Res Int. 2018;2018:9056239doi: 10.1155/2018/9056239.
Selvi, V., Nori, J., Meattini, I., Francolini, G., Morelli, N., De Benedetto, D., Bicchierai, G., Di Naro, F., Gill, M. K., Orzalesi, L., Sanchez, L., Susini, T., Bianchi, S., Livi, L., & Miele, V. (2018). Corrigendum to "Role of Magnetic Resonance Imaging in the Preoperative Staging and Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive Ductolobular Carcinoma". BioMed research international, 20189056239. https://doi.org/10.1155/2018/9056239
Selvi, Valeria, et al. "Corrigendum to "Role of Magnetic Resonance Imaging in the Preoperative Staging and Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive Ductolobular Carcinoma"." BioMed research international vol. 2018 (2018): 9056239. doi: https://doi.org/10.1155/2018/9056239
Selvi V, Nori J, Meattini I, Francolini G, Morelli N, De Benedetto D, Bicchierai G, Di Naro F, Gill MK, Orzalesi L, Sanchez L, Susini T, Bianchi S, Livi L, Miele V. Corrigendum to "Role of Magnetic Resonance Imaging in the Preoperative Staging and Work-Up of Patients Affected by Invasive Lobular Carcinoma or Invasive Ductolobular Carcinoma". Biomed Res Int. 2018 Sep 06;2018:9056239. doi: 10.1155/2018/9056239. eCollection 2018. PMID: 30258852; PMCID: PMC6146621.
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Understanding Chinese Medicine Patterns of Rheumatoid Arthritis and Related Biomarkers.

Medicines (Basel, Switzerland)

Seca S, Franconi G.
PMID: 29401671
Medicines (Basel). 2018 Feb 03;5(1). doi: 10.3390/medicines5010017.

No abstract available.

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Seca S, Franconi G. Understanding Chinese Medicine Patterns of Rheumatoid Arthritis and Related Biomarkers. Medicines (Basel). 2018;5(1)doi: 10.3390/medicines5010017.
Seca, S., & Franconi, G. (2018). Understanding Chinese Medicine Patterns of Rheumatoid Arthritis and Related Biomarkers. Medicines (Basel, Switzerland), 5(1), . https://doi.org/10.3390/medicines5010017
Seca, Susana, and Franconi, Giovanna. "Understanding Chinese Medicine Patterns of Rheumatoid Arthritis and Related Biomarkers." Medicines (Basel, Switzerland) vol. 5,1 (2018). doi: https://doi.org/10.3390/medicines5010017
Seca S, Franconi G. Understanding Chinese Medicine Patterns of Rheumatoid Arthritis and Related Biomarkers. Medicines (Basel). 2018 Feb 03;5(1). doi: 10.3390/medicines5010017. PMID: 29401671; PMCID: PMC5874582.
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Proteotoxic Stress and Cell Death in Cancer Cells.

Cancers

Brancolini C, Iuliano L.
PMID: 32842524
Cancers (Basel). 2020 Aug 23;12(9). doi: 10.3390/cancers12092385.

To maintain proteostasis, cells must integrate information and activities that supervise protein synthesis, protein folding, conformational stability, and also protein degradation. Extrinsic and intrinsic conditions can both impact normal proteostasis, causing the appearance of proteotoxic stress. Initially, proteotoxic stress...

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Brancolini C, Iuliano L. Proteotoxic Stress and Cell Death in Cancer Cells. Cancers (Basel). 2020;12(9)doi: 10.3390/cancers12092385.
Brancolini, C., & Iuliano, L. (2020). Proteotoxic Stress and Cell Death in Cancer Cells. Cancers, 12(9), . https://doi.org/10.3390/cancers12092385
Brancolini, Claudio, and Iuliano, Luca. "Proteotoxic Stress and Cell Death in Cancer Cells." Cancers vol. 12,9 (2020). doi: https://doi.org/10.3390/cancers12092385
Brancolini C, Iuliano L. Proteotoxic Stress and Cell Death in Cancer Cells. Cancers (Basel). 2020 Aug 23;12(9). doi: 10.3390/cancers12092385. PMID: 32842524; PMCID: PMC7563887.
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