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Comparative study of curcumin and curcumin formulated in a solid dispersion: Evaluation of their antigenotoxic effects.

Genetics and molecular biology

Mendonça LM, Machado Cda S, Teixeira CC, Freitas LA, Bianchi ML, Antunes LM.
PMID: 26537603
Genet Mol Biol. 2015 Dec;38(4):490-8. doi: 10.1590/S1415-475738420150046. Epub 2015 Nov 03.

Curcumin (CMN) is the principal active component derived from the rhizome of Curcuma longa (Curcuma longa L.). It is a liposoluble polyphenolic compound that possesses great therapeutic potential. Its clinical application is, however, limited by the low concentrations detected...

Femtosecond and temperature-dependent picosecond dynamics of ultrafast excited-state proton transfer in water-dioxane mixtures.

The journal of physical chemistry. A

Freitas AA, Quina FH, Maçanita AA.
PMID: 24925753
J Phys Chem A. 2014 Nov 13;118(45):10448-55. doi: 10.1021/jp504189m. Epub 2014 Jun 13.

Synthetic flavylium salts like the 7-hydroxy-4-methylflavylium (HMF) cation have been used as prototypes to study the chemistry and photochemistry of anthocyanins, the major group of water-soluble pigments in the plant kingdom. In this work, a combination of fluorescence upconversion...

GPCRTree: online hierarchical classification of GPCR function.

BMC research notes

Davies MN, Secker A, Halling-Brown M, Moss DS, Freitas AA, Timmis J, Clark E, Flower DR.
PMID: 18717986
BMC Res Notes. 2008 Aug 21;1:67. doi: 10.1186/1756-0500-1-67.

BACKGROUND: G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary...

Ditylenchus drepanocercus Rediscovered in the Neotropics Causing Angular Leaf Spots on Miconia calvescens.

Journal of nematology

Seixas CD, Barreto RW, Freitas LG, Monteiro FT, Oliveira RD.
PMID: 19262828
J Nematol. 2004 Dec;36(4):481-6.

During searches for pathogens to be used as classical biocontrol agents for Miconia calvescens (velvet tree), a devastating plant invader of Hawaii and French Polynesia, damaging angular leaf spots were found repeatedly. The etiological agent of this disease was...

Variability of Meloidogyne exigua on Coffee in the Zona da Mata of Minas Gerais State, Brazil.

Journal of nematology

Oliveira DS, Oliveira RD, Freitas LG, Silva RV.
PMID: 19262880
J Nematol. 2005 Sep;37(3):323-7.

Minas Gerais is the major coffee-producing state of Brazil, with 28% of its production coming from the region of Zona da Mata. Four major species of root-knot nematode attacking coffee (Meloidogyne incognita, M. paranaensis, M. coffeicola, and M. exigua)...

Bovine papillomavirus E2 and E5 gene expression in sperm cells of healthy bulls.

Virusdisease

Silva MA, Silva EC, Gurgel AP, Nascimento KC, Freitas AC.
PMID: 24426320
Virusdisease. 2014 Jan;25(1):125-8. doi: 10.1007/s13337-013-0185-5. Epub 2013 Nov 30.

Papillomaviruses are found in epithelial lesions and are linked to different carcinogenic processes in humans and other animals. Although BPV has been characterized as epitheliotropic, the presence of viral DNA has been detected in other tissues and fluids, such...

Antibacterial effect of root canal preparation and calcium hydroxide paste (Calen) intracanal dressing in primary teeth with apical periodontitis.

Journal of applied oral science : revista FOB

Faria G, Nelson-Filho P, Freitas AC, Assed S, Ito IY.
PMID: 20865218
J Appl Oral Sci. 2005 Dec;13(4):351-5. doi: 10.1590/s1678-77572005000400007.

The aim of this study was to evaluate the antibacterial action of root canal mechanical preparation using 2.5% sodium hypochlorite as the irrigating solution and a calcium hydroxide paste as the antibacterial intracanal dressing in human primary teeth root...

Mortality associated with influenza in tropics, state of são paulo, Brazil, from 2002 to 2011: the pre-pandemic, pandemic, and post-pandemic periods.

Influenza research and treatment

Freitas AR, Francisco PM, Donalisio MR.
PMID: 23844285
Influenza Res Treat. 2013;2013:696274. doi: 10.1155/2013/696274. Epub 2013 Jun 12.

The impact of the seasonal influenza and 2009 AH1N1 pandemic influenza on mortality is not yet completely understood, particularly in tropical and subtropical countries. The trends of influenza related mortality rate in different age groups and different outcomes on...

Biological Activities of Libidibia (Caesalpinia) ferrea var. parvifolia (Mart. ex Tul.) L. P. Queiroz Pod Preparations.

Evidence-based complementary and alternative medicine : eCAM

Freitas AC, Ximenes NC, Aguiar JS, Nascimento SC, Lins TU, Magalhães LR, Coelho LC, Carneiro-da-Cunha MG, Gonçalves-Silva T, Correia MT.
PMID: 22675382
Evid Based Complement Alternat Med. 2012;2012:514134. doi: 10.1155/2012/514134. Epub 2012 May 23.

Libidibia ferrea has been used in folk medicine throughout Brazil, and this study evaluated the biological activities of crude extract (CE) as well as a partially purified fraction (F80) obtained from its pods. Results from the MTT assay revealed...

Aging and End Stage Renal Disease Cause A Decrease in Absolute Circulating Lymphocyte Counts with A Shift to A Memory Profile and Diverge in Treg Population.

Aging and disease

Freitas GRR, da Luz Fernandes M, Agena F, Jaluul O, Silva SC, Lemos FBC, Coelho V, Elias DN, Galante NZ.
PMID: 30705767
Aging Dis. 2019 Feb 01;10(1):49-61. doi: 10.14336/AD.2018.0318. eCollection 2019 Feb.

There is a growing number of elderly kidney transplant (Ktx) recipients. Elderly recipients present lower acute rejection rates but higher incidence of infection and malignancies. Aging

Study on the regioselectivity of the N-ethylation reaction of .

Beilstein journal of organic chemistry

Batalha PN, Forezi LDSM, Freitas MCR, Tolentino NMC, Orestes E, Carneiro JWM, Boechat FDCS, de Souza MCBV.
PMID: 30873225
Beilstein J Org Chem. 2019 Feb 12;15:388-400. doi: 10.3762/bjoc.15.35. eCollection 2019.

4-Oxoquinolines are a class of organic substances of great importance in medicinal chemistry, due to their biological and synthetic versatility.

Pure Mandibular Incisor Intrusion: A Finite Element Study to Evaluate the Segmented Arch Technique.

Materials (Basel, Switzerland)

de Brito GM, Brito HHA, Marra GGM, Freitas LRP, Hargreaves BO, Magalhães PAA, Oliveira DD.
PMID: 31470584
Materials (Basel). 2019 Aug 29;12(17). doi: 10.3390/ma12172784.

Leveling the curve of Spee is a commonly-used strategy to correct deep bites. Although several techniques have been proposed to intrude mandibular incisors (MI), flaring of these teeth is often observed and in many instances undesired. A three-dimensional (3D)...

Showing 1 to 12 of 129 entries