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Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification.

In silico pharmacology

Krauss M, Burghaus R, Lippert J, Niemi M, Neuvonen P, Schuppert A, Willmann S, Kuepfer L, Görlitz L.
PMID: 25505651
In Silico Pharmacol. 2013 Apr 11;1:6. doi: 10.1186/2193-9616-1-6. eCollection 2013.

PURPOSE: Inter-individual variability in clinical endpoints and occurrence of potentially severe adverse effects represent an enormous challenge in drug development at all phases of (pre-)clinical research. To ensure patient safety it is important to identify adverse events or critical...

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Krauss M, Burghaus R, Lippert J, et al. Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification. In Silico Pharmacol. 2013;1:6doi: 10.1186/2193-9616-1-6.
Krauss, M., Burghaus, R., Lippert, J., Niemi, M., Neuvonen, P., Schuppert, A., Willmann, S., Kuepfer, L., & Görlitz, L. (2013). Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification. In silico pharmacology, 16. https://doi.org/10.1186/2193-9616-1-6
Krauss, Markus, et al. "Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification." In silico pharmacology vol. 1 (2013): 6. doi: https://doi.org/10.1186/2193-9616-1-6
Krauss M, Burghaus R, Lippert J, Niemi M, Neuvonen P, Schuppert A, Willmann S, Kuepfer L, Görlitz L. Using Bayesian-PBPK modeling for assessment of inter-individual variability and subgroup stratification. In Silico Pharmacol. 2013 Apr 11;1:6. doi: 10.1186/2193-9616-1-6. eCollection 2013. PMID: 25505651; PMCID: PMC4230716.
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Synthesis and magnetic characterization of MnAs nanoparticles via nanoparticle conversion.

Nanotechnology

Wolff MF, Görlitz D, Nielsch K, Messing ME, Deppert K.
PMID: 21178252
Nanotechnology. 2011 Feb 04;22(5):055602. doi: 10.1088/0957-4484/22/5/055602. Epub 2010 Dec 23.

We report on the synthesis of ferromagnetic manganese arsenide (MnAs) nanoparticles via the conversion of primary Mn particles which are generated in an aerosol process in a spark discharge generator. After sintering and size selection in an aerosol setup,...

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Wolff MF, Görlitz D, Nielsch K, et al. Synthesis and magnetic characterization of MnAs nanoparticles via nanoparticle conversion. Nanotechnology. 2010;22(5):055602doi: 10.1088/0957-4484/22/5/055602.
Wolff, M. F., Görlitz, D., Nielsch, K., Messing, M. E., & Deppert, K. (2011). Synthesis and magnetic characterization of MnAs nanoparticles via nanoparticle conversion. Nanotechnology, 22(5), 055602. https://doi.org/10.1088/0957-4484/22/5/055602
Wolff, M F H, et al. "Synthesis and magnetic characterization of MnAs nanoparticles via nanoparticle conversion." Nanotechnology vol. 22,5 (2011): 055602. doi: https://doi.org/10.1088/0957-4484/22/5/055602
Wolff MF, Görlitz D, Nielsch K, Messing ME, Deppert K. Synthesis and magnetic characterization of MnAs nanoparticles via nanoparticle conversion. Nanotechnology. 2011 Feb 04;22(5):055602. doi: 10.1088/0957-4484/22/5/055602. Epub 2010 Dec 23. PMID: 21178252.
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Electronic coupling through intramolecular π-π interactions in biscobaltocenes: a structural, spectroscopic, and magnetic study.

Chemistry (Weinheim an der Bergstrasse, Germany)

Pagels N, Albrecht O, Görlitz D, Rogachev AY, Prosenc MH, Heck J.
PMID: 21381141
Chemistry. 2011 Apr 04;17(15):4166-76. doi: 10.1002/chem.201003462. Epub 2011 Mar 04.

The paramagnetic dinuclear complexes 1,8-bis(cobaltocenyl)naphthalene (2) and 1,8-bis[(pentamethyl-η(5)-cyclopentadienyl)(η(5)-cyclopentadiendiyl)cobalt(II)]naphthalene (4) were synthesized. The molecular structures were characterized by X-ray structure analysis and consisted of two cobaltocenes linked through a distorted naphthalene clamp. Electronic interactions between the two cobalt atoms were...

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Pagels N, Albrecht O, Görlitz D, et al. Electronic coupling through intramolecular π-π interactions in biscobaltocenes: a structural, spectroscopic, and magnetic study. Chemistry. 2011;17(15):4166-76doi: 10.1002/chem.201003462.
Pagels, N., Albrecht, O., Görlitz, D., Rogachev, A. Y., Prosenc, M. H., & Heck, J. (2011). Electronic coupling through intramolecular π-π interactions in biscobaltocenes: a structural, spectroscopic, and magnetic study. Chemistry (Weinheim an der Bergstrasse, Germany), 17(15), 4166-76. https://doi.org/10.1002/chem.201003462
Pagels, Nils, et al. "Electronic coupling through intramolecular π-π interactions in biscobaltocenes: a structural, spectroscopic, and magnetic study." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 17,15 (2011): 4166-76. doi: https://doi.org/10.1002/chem.201003462
Pagels N, Albrecht O, Görlitz D, Rogachev AY, Prosenc MH, Heck J. Electronic coupling through intramolecular π-π interactions in biscobaltocenes: a structural, spectroscopic, and magnetic study. Chemistry. 2011 Apr 04;17(15):4166-76. doi: 10.1002/chem.201003462. Epub 2011 Mar 04. PMID: 21381141.
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Stacked nickelocenes: synthesis, structural characterization, and magnetic properties.

Inorganic chemistry

Trtica S, Prosenc MH, Schmidt M, Heck J, Albrecht O, Görlitz D, Reuter F, Rentschler E.
PMID: 20085267
Inorg Chem. 2010 Feb 15;49(4):1667-73. doi: 10.1021/ic902058n.

The disubstitution of 1,8-diiodonaphthalene (1) with cyclopentadienyl nucleophiles reveals 1,8-(dicyclopentadienyl)-naphthalene, which rapidly undergoes Diels-Alder reaction forming 1,8-(3a',4',7',7a'-tetrahydro-4',7'-methanoindene-7a',8'-diyl)-naphthalene (2). A subsequent retro-Diels-Alder reaction in the presence of sodium hydride yields the disodium salt of 1,8-(dicyclopentadiendiyl)-naphthalene 3. The disodium salt 3...

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Trtica S, Prosenc MH, Schmidt M, et al. Stacked nickelocenes: synthesis, structural characterization, and magnetic properties. Inorg Chem. 2010;49(4):1667-73doi: 10.1021/ic902058n.
Trtica, S., Prosenc, M. H., Schmidt, M., Heck, J., Albrecht, O., Görlitz, D., Reuter, F., & Rentschler, E. (2010). Stacked nickelocenes: synthesis, structural characterization, and magnetic properties. Inorganic chemistry, 49(4), 1667-73. https://doi.org/10.1021/ic902058n
Trtica, Sabrina, et al. "Stacked nickelocenes: synthesis, structural characterization, and magnetic properties." Inorganic chemistry vol. 49,4 (2010): 1667-73. doi: https://doi.org/10.1021/ic902058n
Trtica S, Prosenc MH, Schmidt M, Heck J, Albrecht O, Görlitz D, Reuter F, Rentschler E. Stacked nickelocenes: synthesis, structural characterization, and magnetic properties. Inorg Chem. 2010 Feb 15;49(4):1667-73. doi: 10.1021/ic902058n. PMID: 20085267.
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Monte Carlo simulations of a single polymer chain under extension above and below the Theta temperature.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics

Göritz D, Kreitmeier S, Wittkop M.
PMID: 9964319
Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1996 Jan;53(1):838-845. doi: 10.1103/physreve.53.838.

No abstract available.

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Göritz D, Kreitmeier S, Wittkop M. Monte Carlo simulations of a single polymer chain under extension above and below the Theta temperature. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1996;53(1):838-845doi: 10.1103/physreve.53.838.
Göritz, D., Kreitmeier, S., & Wittkop, M. (1996). Monte Carlo simulations of a single polymer chain under extension above and below the Theta temperature. Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics, 53(1), 838-845. https://doi.org/10.1103/physreve.53.838
Göritz, et al. "Monte Carlo simulations of a single polymer chain under extension above and below the Theta temperature." Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics vol. 53,1 (1996): 838-845. doi: https://doi.org/10.1103/physreve.53.838
Göritz D, Kreitmeier S, Wittkop M. Monte Carlo simulations of a single polymer chain under extension above and below the Theta temperature. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 1996 Jan;53(1):838-845. doi: 10.1103/physreve.53.838. PMID: 9964319.
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The ferredoxin-encoding fdxN gene of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 is not essential for nitrogen fixation.

The New phytologist

Masepohl B, Görlitz K, Monnerjahn U, Moslerand B, Böhme H.
PMID: 33863005
New Phytol. 1997 Jul;136(3):419-423. doi: 10.1046/j.1469-8137.1997.00771.x.

In contrast to that of Anabaena sp. PCC7120, the fdxN gene in Anabaena variabilis ATCC 29413 is not interrupted by a 55-kb DNA element, making this strain more suitable for genetic analysis of fdxN independent of the developmentally regulated...

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Masepohl B, Görlitz K, Monnerjahn U, et al. The ferredoxin-encoding fdxN gene of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 is not essential for nitrogen fixation. New Phytol. 1997;136(3):419-423doi: 10.1046/j.1469-8137.1997.00771.x.
Masepohl, B., Görlitz, K., Monnerjahn, U., Moslerand, B., & Böhme, H. (1997). The ferredoxin-encoding fdxN gene of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 is not essential for nitrogen fixation. The New phytologist, 136(3), 419-423. https://doi.org/10.1046/j.1469-8137.1997.00771.x
Masepohl, Bernd, et al. "The ferredoxin-encoding fdxN gene of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 is not essential for nitrogen fixation." The New phytologist vol. 136,3 (1997): 419-423. doi: https://doi.org/10.1046/j.1469-8137.1997.00771.x
Masepohl B, Görlitz K, Monnerjahn U, Moslerand B, Böhme H. The ferredoxin-encoding fdxN gene of the filamentous cyanobacterium Anabaena variabilis ATCC 29413 is not essential for nitrogen fixation. New Phytol. 1997 Jul;136(3):419-423. doi: 10.1046/j.1469-8137.1997.00771.x. PMID: 33863005.
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Loss of superconducting phase coherence in YBa(2)Cu(3)O(7) films: vortex-loop unbinding and Kosterlitz-Thouless phenomena.

Physical review letters

Kötzler J, Görlitz D, Skwirblies S, Wriedt A.
PMID: 11580544
Phys Rev Lett. 2001 Sep 17;87(12):127005. doi: 10.1103/PhysRevLett.87.127005. Epub 2001 Aug 31.

The linear conductance G' + iG(") parallel to the CuO(2) planes of flat d = 50-600 nm thin films is measured between 30 mHz and 800 kHz. The decay of the phase-coherent superfluid density signals the proliferation of 3D...

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Kötzler J, Görlitz D, Skwirblies S, et al. Loss of superconducting phase coherence in YBa(2)Cu(3)O(7) films: vortex-loop unbinding and Kosterlitz-Thouless phenomena. Phys Rev Lett. 2001;87(12):127005doi: 10.1103/PhysRevLett.87.127005.
Kötzler, J., Görlitz, D., Skwirblies, S., & Wriedt, A. (2001). Loss of superconducting phase coherence in YBa(2)Cu(3)O(7) films: vortex-loop unbinding and Kosterlitz-Thouless phenomena. Physical review letters, 87(12), 127005. https://doi.org/10.1103/PhysRevLett.87.127005
Kötzler, J, et al. "Loss of superconducting phase coherence in YBa(2)Cu(3)O(7) films: vortex-loop unbinding and Kosterlitz-Thouless phenomena." Physical review letters vol. 87,12 (2001): 127005. doi: https://doi.org/10.1103/PhysRevLett.87.127005
Kötzler J, Görlitz D, Skwirblies S, Wriedt A. Loss of superconducting phase coherence in YBa(2)Cu(3)O(7) films: vortex-loop unbinding and Kosterlitz-Thouless phenomena. Phys Rev Lett. 2001 Sep 17;87(12):127005. doi: 10.1103/PhysRevLett.87.127005. Epub 2001 Aug 31. PMID: 11580544.
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Observation of vortex phase singularities in Bose-Einstein condensates.

Physical review letters

Inouye S, Gupta S, Rosenband T, Chikkatur AP, Görlitz A, Gustavson TL, Leanhardt AE, Pritchard DE, Ketterle W.
PMID: 11497929
Phys Rev Lett. 2001 Aug 20;87(8):080402. doi: 10.1103/PhysRevLett.87.080402. Epub 2001 Aug 02.

We have observed phase singularities due to vortex excitation in Bose-Einstein condensates. Vortices were created by moving a laser beam through a condensate. They were observed as dislocations in the interference fringes formed by the stirred condensate and a...

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Inouye S, Gupta S, Rosenband T, et al. Observation of vortex phase singularities in Bose-Einstein condensates. Phys Rev Lett. 2001;87(8):080402doi: 10.1103/PhysRevLett.87.080402.
Inouye, S., Gupta, S., Rosenband, T., Chikkatur, A. P., Görlitz, A., Gustavson, T. L., Leanhardt, A. E., Pritchard, D. E., & Ketterle, W. (2001). Observation of vortex phase singularities in Bose-Einstein condensates. Physical review letters, 87(8), 080402. https://doi.org/10.1103/PhysRevLett.87.080402
Inouye, S, et al. "Observation of vortex phase singularities in Bose-Einstein condensates." Physical review letters vol. 87,8 (2001): 080402. doi: https://doi.org/10.1103/PhysRevLett.87.080402
Inouye S, Gupta S, Rosenband T, Chikkatur AP, Görlitz A, Gustavson TL, Leanhardt AE, Pritchard DE, Ketterle W. Observation of vortex phase singularities in Bose-Einstein condensates. Phys Rev Lett. 2001 Aug 20;87(8):080402. doi: 10.1103/PhysRevLett.87.080402. Epub 2001 Aug 02. PMID: 11497929.
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Simulations on the number of entanglements of a polymer network using knot theory.

Physical review. E, Statistical, nonlinear, and soft matter physics

Michalke W, Lang M, Kreitmeier S, Göritz D.
PMID: 11461310
Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jul;64(1):012801. doi: 10.1103/PhysRevE.64.012801. Epub 2001 Jun 13.

Polymer networks, created on the computer using the Bond-Fluctuation-Algorithm, offer the possibility to count the number of entanglements. We generated networks consisting of 5000 chains that were cross linked at their end groups via tetra-functional cross linkers. The analysis...

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Michalke W, Lang M, Kreitmeier S, et al. Simulations on the number of entanglements of a polymer network using knot theory. Phys Rev E Stat Nonlin Soft Matter Phys. 2001;64(1):012801doi: 10.1103/PhysRevE.64.012801.
Michalke, W., Lang, M., Kreitmeier, S., & Göritz, D. (2001). Simulations on the number of entanglements of a polymer network using knot theory. Physical review. E, Statistical, nonlinear, and soft matter physics, 64(1), 012801. https://doi.org/10.1103/PhysRevE.64.012801
Michalke, W, et al. "Simulations on the number of entanglements of a polymer network using knot theory." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 64,1 (2001): 012801. doi: https://doi.org/10.1103/PhysRevE.64.012801
Michalke W, Lang M, Kreitmeier S, Göritz D. Simulations on the number of entanglements of a polymer network using knot theory. Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jul;64(1):012801. doi: 10.1103/PhysRevE.64.012801. Epub 2001 Jun 13. PMID: 11461310.
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Controlled-pore silica glass modified with N-propylsalicylaldimine for the separation and preconcentration of trace Al(III), Ag(I) and Hg(II) in water samples.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

Mostafa GA, Hassanien MM, Abou-El-Sherbini KS, Görlitz V.
PMID: 12945668
Anal Sci. 2003 Aug;19(8):1151-6. doi: 10.2116/analsci.19.1151.

Controlled-pore silica glass modified with N-propylsalicylaldimine (SCPSG) has been investigated as a surface-active matrix for the separation of some metal ions. The porous silica glass base was confirmed to have better stability towards hydrolysis in aqueous solution buffered at...

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Mostafa GA, Hassanien MM, Abou-El-Sherbini KS, et al. Controlled-pore silica glass modified with N-propylsalicylaldimine for the separation and preconcentration of trace Al(III), Ag(I) and Hg(II) in water samples. Anal Sci. 2003;19(8):1151-6doi: 10.2116/analsci.19.1151.
Mostafa, G. A., Hassanien, M. M., Abou-El-Sherbini, K. S., & Görlitz, V. (2003). Controlled-pore silica glass modified with N-propylsalicylaldimine for the separation and preconcentration of trace Al(III), Ag(I) and Hg(II) in water samples. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(8), 1151-6. https://doi.org/10.2116/analsci.19.1151
Mostafa, Gamal A E, et al. "Controlled-pore silica glass modified with N-propylsalicylaldimine for the separation and preconcentration of trace Al(III), Ag(I) and Hg(II) in water samples." Analytical sciences : the international journal of the Japan Society for Analytical Chemistry vol. 19,8 (2003): 1151-6. doi: https://doi.org/10.2116/analsci.19.1151
Mostafa GA, Hassanien MM, Abou-El-Sherbini KS, Görlitz V. Controlled-pore silica glass modified with N-propylsalicylaldimine for the separation and preconcentration of trace Al(III), Ag(I) and Hg(II) in water samples. Anal Sci. 2003 Aug;19(8):1151-6. doi: 10.2116/analsci.19.1151. PMID: 12945668.
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Sodium Bose-Einstein condensates in the F = 2 state in a large-volume optical trap.

Physical review letters

Görlitz A, Gustavson TL, Leanhardt AE, Löw R, Chikkatur AP, Gupta S, Inouye S, Pritchard DE, Ketterle W.
PMID: 12689206
Phys Rev Lett. 2003 Mar 07;90(9):090401. doi: 10.1103/PhysRevLett.90.090401. Epub 2003 Mar 04.

We have investigated the properties of Bose-Einstein condensates of sodium atoms in the upper hyperfine ground state. Condensates in the high-field seeking [F=2, m(F)=-2> state were created in a large volume optical trap from initially prepared [F=1, m(F)=-1> condensates...

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Görlitz A, Gustavson TL, Leanhardt AE, et al. Sodium Bose-Einstein condensates in the F = 2 state in a large-volume optical trap. Phys Rev Lett. 2003;90(9):090401doi: 10.1103/PhysRevLett.90.090401.
Görlitz, A., Gustavson, T. L., Leanhardt, A. E., Löw, R., Chikkatur, A. P., Gupta, S., Inouye, S., Pritchard, D. E., & Ketterle, W. (2003). Sodium Bose-Einstein condensates in the F = 2 state in a large-volume optical trap. Physical review letters, 90(9), 090401. https://doi.org/10.1103/PhysRevLett.90.090401
Görlitz, A, et al. "Sodium Bose-Einstein condensates in the F = 2 state in a large-volume optical trap." Physical review letters vol. 90,9 (2003): 090401. doi: https://doi.org/10.1103/PhysRevLett.90.090401
Görlitz A, Gustavson TL, Leanhardt AE, Löw R, Chikkatur AP, Gupta S, Inouye S, Pritchard DE, Ketterle W. Sodium Bose-Einstein condensates in the F = 2 state in a large-volume optical trap. Phys Rev Lett. 2003 Mar 07;90(9):090401. doi: 10.1103/PhysRevLett.90.090401. Epub 2003 Mar 04. PMID: 12689206.
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STED nanoscopy with fluorescent quantum dots.

Nature communications

Hanne J, Falk HJ, Görlitz F, Hoyer P, Engelhardt J, Sahl SJ, Hell SW.
PMID: 25980788
Nat Commun. 2015 May 18;6:7127. doi: 10.1038/ncomms8127.

The widely popular class of quantum-dot molecular labels could so far not be utilized as standard fluorescent probes in STED (stimulated emission depletion) nanoscopy. This is because broad quantum-dot excitation spectra extend deeply into the spectral bands used for...

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Hanne J, Falk HJ, Görlitz F, et al. STED nanoscopy with fluorescent quantum dots. Nat Commun. 2015;6:7127doi: 10.1038/ncomms8127.
Hanne, J., Falk, H. J., Görlitz, F., Hoyer, P., Engelhardt, J., Sahl, S. J., & Hell, S. W. (2015). STED nanoscopy with fluorescent quantum dots. Nature communications, 67127. https://doi.org/10.1038/ncomms8127
Hanne, Janina, et al. "STED nanoscopy with fluorescent quantum dots." Nature communications vol. 6 (2015): 7127. doi: https://doi.org/10.1038/ncomms8127
Hanne J, Falk HJ, Görlitz F, Hoyer P, Engelhardt J, Sahl SJ, Hell SW. STED nanoscopy with fluorescent quantum dots. Nat Commun. 2015 May 18;6:7127. doi: 10.1038/ncomms8127. PMID: 25980788; PMCID: PMC4479004.
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Showing 1 to 12 of 54 entries