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Showing 1 to 12 of 197 entries
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Corrigendum: Arctic megaslide at presumed rest.

Scientific reports

Geissler WH, Gebhardt AC, Gross F, Wollenburg J, Jensen L, Schmidt-Aursch MC, Krastel S, Elger J, Osti G.
PMID: 28513599
Sci Rep. 2017 May 17;7:46821. doi: 10.1038/srep46821.

No abstract available.

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Geissler WH, Gebhardt AC, Gross F, et al. Corrigendum: Arctic megaslide at presumed rest. Sci Rep. 2017;7:46821doi: 10.1038/srep46821.
Geissler, W. H., Gebhardt, A. C., Gross, F., Wollenburg, J., Jensen, L., Schmidt-Aursch, M. C., Krastel, S., Elger, J., & Osti, G. (2017). Corrigendum: Arctic megaslide at presumed rest. Scientific reports, 746821. https://doi.org/10.1038/srep46821
Geissler, Wolfram H, et al. "Corrigendum: Arctic megaslide at presumed rest." Scientific reports vol. 7 (2017): 46821. doi: https://doi.org/10.1038/srep46821
Geissler WH, Gebhardt AC, Gross F, Wollenburg J, Jensen L, Schmidt-Aursch MC, Krastel S, Elger J, Osti G. Corrigendum: Arctic megaslide at presumed rest. Sci Rep. 2017 May 17;7:46821. doi: 10.1038/srep46821. PMID: 28513599; PMCID: PMC5434450.
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Biobanking from the patient perspective.

Research involvement and engagement

Mitchell D, Geissler J, Parry-Jones A, Keulen H, Schmitt DC, Vavassori R, Matharoo-Ball B.
PMID: 29062493
Res Involv Engagem. 2015 Jun 25;1:4. doi: 10.1186/s40900-015-0001-z. eCollection 2015.

PLAIN ENGLISH SUMMARY: Biobanks are collections of donations of biological material (DNA, cells, tissue etc.) and related data which are very valuable for research into human diseases. A variety of biobanks exist for example within hospitals, research institutes, pharmaceutical...

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Mitchell D, Geissler J, Parry-Jones A, et al. Biobanking from the patient perspective. Res Involv Engagem. 2015;1:4doi: 10.1186/s40900-015-0001-z.
Mitchell, D., Geissler, J., Parry-Jones, A., Keulen, H., Schmitt, D. C., Vavassori, R., & Matharoo-Ball, B. (2015). Biobanking from the patient perspective. Research involvement and engagement, 14. https://doi.org/10.1186/s40900-015-0001-z
Mitchell, Derick, et al. "Biobanking from the patient perspective." Research involvement and engagement vol. 1 (2015): 4. doi: https://doi.org/10.1186/s40900-015-0001-z
Mitchell D, Geissler J, Parry-Jones A, Keulen H, Schmitt DC, Vavassori R, Matharoo-Ball B. Biobanking from the patient perspective. Res Involv Engagem. 2015 Jun 25;1:4. doi: 10.1186/s40900-015-0001-z. eCollection 2015. PMID: 29062493; PMCID: PMC5598087.
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Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma.

Frontiers in immunology

van Beek AE, Pouw RB, Brouwer MC, van Mierlo G, Geissler J, Ooijevaar-de Heer P, de Boer M, van Leeuwen K, Rispens T, Wouters D, Kuijpers TW.
PMID: 29093712
Front Immunol. 2017 Oct 18;8:1328. doi: 10.3389/fimmu.2017.01328. eCollection 2017.

The complement factor H-related (FHR) proteins are hypothesized to fine-tune the regulatory role of complement factor H (FH) in the alternative pathway of the complement system. Moreover, FHR-1, FHR-2, and FHR-5 have been proposed to be dimers, which further...

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van Beek AE, Pouw RB, Brouwer MC, et al. Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma. Front Immunol. 2017;8:1328doi: 10.3389/fimmu.2017.01328.
van Beek, A. E., Pouw, R. B., Brouwer, M. C., van Mierlo, G., Geissler, J., Ooijevaar-de Heer, P., de Boer, M., van Leeuwen, K., Rispens, T., Wouters, D., & Kuijpers, T. W. (2017). Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma. Frontiers in immunology, 81328. https://doi.org/10.3389/fimmu.2017.01328
van Beek, Anna E, et al. "Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma." Frontiers in immunology vol. 8 (2017): 1328. doi: https://doi.org/10.3389/fimmu.2017.01328
van Beek AE, Pouw RB, Brouwer MC, van Mierlo G, Geissler J, Ooijevaar-de Heer P, de Boer M, van Leeuwen K, Rispens T, Wouters D, Kuijpers TW. Factor H-Related (FHR)-1 and FHR-2 Form Homo- and Heterodimers, while FHR-5 Circulates Only As Homodimer in Human Plasma. Front Immunol. 2017 Oct 18;8:1328. doi: 10.3389/fimmu.2017.01328. eCollection 2017. PMID: 29093712; PMCID: PMC5651247.
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In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies.

Molecular therapy. Methods & clinical development

Broichhausen C, Riquelme P, Ahrens N, Wege AK, Koehl GE, Schlitt HJ, Banas B, Fändrich F, Geissler EK, Hutchinson JA.
PMID: 26015968
Mol Ther Methods Clin Dev. 2014 Jul 16;1:14026. doi: 10.1038/mtm.2014.26. eCollection 2014.

A new cell-based medicinal product containing human regulatory macrophages, known as Mreg_UKR, has been developed and conforms to expectations of a therapeutic drug. Here, Mreg_UKR was subjected to pharmacokinetic, safety pharmacology, and toxicological testing, which identified no adverse reactions....

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Broichhausen C, Riquelme P, Ahrens N, et al. In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies. Mol Ther Methods Clin Dev. 2014;1:14026doi: 10.1038/mtm.2014.26.
Broichhausen, C., Riquelme, P., Ahrens, N., Wege, A. K., Koehl, G. E., Schlitt, H. J., Banas, B., Fändrich, F., Geissler, E. K., & Hutchinson, J. A. (2014). In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies. Molecular therapy. Methods & clinical development, 114026. https://doi.org/10.1038/mtm.2014.26
Broichhausen, Christiane, et al. "In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies." Molecular therapy. Methods & clinical development vol. 1 (2014): 14026. doi: https://doi.org/10.1038/mtm.2014.26
Broichhausen C, Riquelme P, Ahrens N, Wege AK, Koehl GE, Schlitt HJ, Banas B, Fändrich F, Geissler EK, Hutchinson JA. In question: the scientific value of preclinical safety pharmacology and toxicology studies with cell-based therapies. Mol Ther Methods Clin Dev. 2014 Jul 16;1:14026. doi: 10.1038/mtm.2014.26. eCollection 2014. PMID: 26015968; PMCID: PMC4362366.
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Cold crystalloid cardioplegia.

Multimedia manual of cardiothoracic surgery : MMCTS

Geissler HJ, Mehlhorn U.
PMID: 24415397
Multimed Man Cardiothorac Surg. 2006 Jan 01;2006(109):mmcts.2004.001040. doi: 10.1510/mmcts.2004.001040.

Cold crystalloid cardioplegia is clinically used since the mid-1960s. It is currently applied in adult and pediatric cardiac surgery patients and remains the preferred method of myocardial protection for many cardiac surgeons. This chapter gives a brief overview about...

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Geissler HJ, Mehlhorn U. Cold crystalloid cardioplegia. Multimed Man Cardiothorac Surg. 2006;2006(109):mmcts.2004.001040doi: 10.1510/mmcts.2004.001040.
Geissler, H. J., & Mehlhorn, U. (2006). Cold crystalloid cardioplegia. Multimedia manual of cardiothoracic surgery : MMCTS, 2006(109), mmcts.2004.001040. https://doi.org/10.1510/mmcts.2004.001040
Geissler, Hans J, and Mehlhorn, Uwe. "Cold crystalloid cardioplegia." Multimedia manual of cardiothoracic surgery : MMCTS vol. 2006,109 (2006): mmcts.2004.001040. doi: https://doi.org/10.1510/mmcts.2004.001040
Geissler HJ, Mehlhorn U. Cold crystalloid cardioplegia. Multimed Man Cardiothorac Surg. 2006 Jan 01;2006(109):mmcts.2004.001040. doi: 10.1510/mmcts.2004.001040. PMID: 24415397.
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Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative.

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie

Geissler RG, Kösters C, Franz D, Buddendick H, Borowski M, Juhra C, Lange M, Bunzemeier H, Roeder N, Sibrowski W, Raschke MJ, Schlenke P.
PMID: 26019703
Transfus Med Hemother. 2015 Mar;42(2):83-9. doi: 10.1159/000377735. Epub 2015 Mar 12.

BACKGROUND: The aim of our single-centre retrospective study presented here is to further analyse the utilisation of allogeneic blood components within a 5-year observation period (2009-2013) in trauma surgery (15,457 patients) under the measures of an educational patient blood...

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Geissler RG, Kösters C, Franz D, et al. Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative. Transfus Med Hemother. 2015;42(2):83-9doi: 10.1159/000377735.
Geissler, R. G., Kösters, C., Franz, D., Buddendick, H., Borowski, M., Juhra, C., Lange, M., Bunzemeier, H., Roeder, N., Sibrowski, W., Raschke, M. J., & Schlenke, P. (2015). Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative. Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 42(2), 83-9. https://doi.org/10.1159/000377735
Geissler, Raoul Georg, et al. "Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative." Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie vol. 42,2 (2015): 83-9. doi: https://doi.org/10.1159/000377735
Geissler RG, Kösters C, Franz D, Buddendick H, Borowski M, Juhra C, Lange M, Bunzemeier H, Roeder N, Sibrowski W, Raschke MJ, Schlenke P. Utilisation of Blood Components in Trauma Surgery: A Single-Centre, Retrospective Analysis before and after the Implementation of an Educative PBM Initiative. Transfus Med Hemother. 2015 Mar;42(2):83-9. doi: 10.1159/000377735. Epub 2015 Mar 12. PMID: 26019703; PMCID: PMC4439836.
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Novel drugs that target the metabolic reprogramming in renal cell cancer.

Cancer & metabolism

van der Mijn JC, Panka DJ, Geissler AK, Verheul HM, Mier JW.
PMID: 27418963
Cancer Metab. 2016 Jul 13;4:14. doi: 10.1186/s40170-016-0154-8. eCollection 2016.

Molecular profiling studies of tumor tissue from patients with clear cell renal cell cancer (ccRCC) have revealed extensive metabolic reprogramming in this disease. Associations were found between metabolic reprogramming, histopathologic Fuhrman grade, and overall survival of patients. Large-scale genomics,...

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van der Mijn JC, Panka DJ, Geissler AK, et al. Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer Metab. 2016;4:14doi: 10.1186/s40170-016-0154-8.
van der Mijn, J. C., Panka, D. J., Geissler, A. K., Verheul, H. M., & Mier, J. W. (2016). Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer & metabolism, 414. https://doi.org/10.1186/s40170-016-0154-8
van der Mijn, Johannes C, et al. "Novel drugs that target the metabolic reprogramming in renal cell cancer." Cancer & metabolism vol. 4 (2016): 14. doi: https://doi.org/10.1186/s40170-016-0154-8
van der Mijn JC, Panka DJ, Geissler AK, Verheul HM, Mier JW. Novel drugs that target the metabolic reprogramming in renal cell cancer. Cancer Metab. 2016 Jul 13;4:14. doi: 10.1186/s40170-016-0154-8. eCollection 2016. PMID: 27418963; PMCID: PMC4944519.
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Response to Courtney et al.

Bone

Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC.
PMID: 25813582
Bone. 2016 Aug;89:77-79. doi: 10.1016/j.bone.2015.03.007. Epub 2015 Mar 24.

No abstract available.

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Bajaj D, Geissler JR, Allen MR, et al. Response to Courtney et al. Bone. 2015;89:77-79doi: 10.1016/j.bone.2015.03.007.
Bajaj, D., Geissler, J. R., Allen, M. R., Burr, D. B., & Fritton, J. C. (2016). Response to Courtney et al. Bone, 8977-79. https://doi.org/10.1016/j.bone.2015.03.007
Bajaj, Devendra, et al. "Response to Courtney et al." Bone vol. 89 (2016): 77-79. doi: https://doi.org/10.1016/j.bone.2015.03.007
Bajaj D, Geissler JR, Allen MR, Burr DB, Fritton JC. Response to Courtney et al. Bone. 2016 Aug;89:77-79. doi: 10.1016/j.bone.2015.03.007. Epub 2015 Mar 24. PMID: 25813582.
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Ligand-Mediated Interactions between Nanoscale Surfaces Depend Sensitively and Nonlinearly on Temperature, Facet Dimensions, and Ligand Coverage.

ACS nano

Widmer-Cooper A, Geissler PL.
PMID: 26756464
ACS Nano. 2016 Feb 23;10(2):1877-87. doi: 10.1021/acsnano.5b05569. Epub 2016 Jan 20.

Nanoparticles are often covered in ligand monolayers, which can undergo a temperature-dependent order-disorder transition that switches the particle-particle interaction from repulsive to attractive in solution. In this work, we examine how changes in the ligand surface coverage and facet...

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Widmer-Cooper A, Geissler PL. Ligand-Mediated Interactions between Nanoscale Surfaces Depend Sensitively and Nonlinearly on Temperature, Facet Dimensions, and Ligand Coverage. ACS Nano. 2016;10(2):1877-87doi: 10.1021/acsnano.5b05569.
Widmer-Cooper, A., & Geissler, P. L. (2016). Ligand-Mediated Interactions between Nanoscale Surfaces Depend Sensitively and Nonlinearly on Temperature, Facet Dimensions, and Ligand Coverage. ACS nano, 10(2), 1877-87. https://doi.org/10.1021/acsnano.5b05569
Widmer-Cooper, Asaph, and Geissler, Phillip L. "Ligand-Mediated Interactions between Nanoscale Surfaces Depend Sensitively and Nonlinearly on Temperature, Facet Dimensions, and Ligand Coverage." ACS nano vol. 10,2 (2016): 1877-87. doi: https://doi.org/10.1021/acsnano.5b05569
Widmer-Cooper A, Geissler PL. Ligand-Mediated Interactions between Nanoscale Surfaces Depend Sensitively and Nonlinearly on Temperature, Facet Dimensions, and Ligand Coverage. ACS Nano. 2016 Feb 23;10(2):1877-87. doi: 10.1021/acsnano.5b05569. Epub 2016 Jan 20. PMID: 26756464.
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Autoionization in liquid water.

Science (New York, N.Y.)

Geissler PL, Dellago C, Chandler D, Hutter J, Parrinello M.
PMID: 11251111
Science. 2001 Mar 16;291(5511):2121-4. doi: 10.1126/science.1056991.

The dissociation of a water molecule in liquid water is the fundamental event in acid-base chemistry, determining the pH of water. Because of the short time scales and microscopic length scales involved, the dynamics of this autoionization have not...

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Geissler PL, Dellago C, Chandler D, et al. Autoionization in liquid water. Science. 2001;291(5511):2121-4doi: 10.1126/science.1056991.
Geissler, P. L., Dellago, C., Chandler, D., Hutter, J., & Parrinello, M. (2001). Autoionization in liquid water. Science (New York, N.Y.), 291(5511), 2121-4. https://doi.org/10.1126/science.1056991
Geissler, P L, et al. "Autoionization in liquid water." Science (New York, N.Y.) vol. 291,5511 (2001): 2121-4. doi: https://doi.org/10.1126/science.1056991
Geissler PL, Dellago C, Chandler D, Hutter J, Parrinello M. Autoionization in liquid water. Science. 2001 Mar 16;291(5511):2121-4. doi: 10.1126/science.1056991. PMID: 11251111.
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Phytotropins: III. NAPHTHYLPHTHALAMIC ACID BINDING SITES ON MAIZE COLEOPTILE MEMBRANES AS POSSIBLE RECEPTOR SITES FOR PHYTOTROPIN ACTION.

Plant physiology

Katekar GF, Navé JF, Geissler AE.
PMID: 16662126
Plant Physiol. 1981 Dec;68(6):1460-4. doi: 10.1104/pp.68.6.1460.

Certain members of the phytotropin class of auxin transport inhibitors are shown to bind with high affinity to the known naphthylphthalamic acid binding sites in maize (Zea mays) coleoptiles. The binding site is, thus, a phytotropin binding site. In...

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Katekar GF, Navé JF, Geissler AE. Phytotropins: III. NAPHTHYLPHTHALAMIC ACID BINDING SITES ON MAIZE COLEOPTILE MEMBRANES AS POSSIBLE RECEPTOR SITES FOR PHYTOTROPIN ACTION. Plant Physiol. 1981;68(6):1460-4doi: 10.1104/pp.68.6.1460.
Katekar, G. F., Navé, J. F., & Geissler, A. E. (1981). Phytotropins: III. NAPHTHYLPHTHALAMIC ACID BINDING SITES ON MAIZE COLEOPTILE MEMBRANES AS POSSIBLE RECEPTOR SITES FOR PHYTOTROPIN ACTION. Plant physiology, 68(6), 1460-4. https://doi.org/10.1104/pp.68.6.1460
Katekar, G F, et al. "Phytotropins: III. NAPHTHYLPHTHALAMIC ACID BINDING SITES ON MAIZE COLEOPTILE MEMBRANES AS POSSIBLE RECEPTOR SITES FOR PHYTOTROPIN ACTION." Plant physiology vol. 68,6 (1981): 1460-4. doi: https://doi.org/10.1104/pp.68.6.1460
Katekar GF, Navé JF, Geissler AE. Phytotropins: III. NAPHTHYLPHTHALAMIC ACID BINDING SITES ON MAIZE COLEOPTILE MEMBRANES AS POSSIBLE RECEPTOR SITES FOR PHYTOTROPIN ACTION. Plant Physiol. 1981 Dec;68(6):1460-4. doi: 10.1104/pp.68.6.1460. PMID: 16662126; PMCID: PMC426121.
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Auxin Transport Inhibitors: IV. EVIDENCE OF A COMMON MODE OF ACTION FOR A PROPOSED CLASS OF AUXIN TRANSPORT INHIBITORS: THE PHYTOTROPINS.

Plant physiology

Katekar GF, Geissler AE.
PMID: 16661601
Plant Physiol. 1980 Dec;66(6):1190-5. doi: 10.1104/pp.66.6.1190.

The more active members of a proposed class of auxin transport inhibitors have been shown to have the ability to inhibit the active movement of auxin at concentrations where they have little effect on auxin action and no significant...

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Katekar GF, Geissler AE. Auxin Transport Inhibitors: IV. EVIDENCE OF A COMMON MODE OF ACTION FOR A PROPOSED CLASS OF AUXIN TRANSPORT INHIBITORS: THE PHYTOTROPINS. Plant Physiol. 1980;66(6):1190-5doi: 10.1104/pp.66.6.1190.
Katekar, G. F., & Geissler, A. E. (1980). Auxin Transport Inhibitors: IV. EVIDENCE OF A COMMON MODE OF ACTION FOR A PROPOSED CLASS OF AUXIN TRANSPORT INHIBITORS: THE PHYTOTROPINS. Plant physiology, 66(6), 1190-5. https://doi.org/10.1104/pp.66.6.1190
Katekar, G F, and Geissler, A E. "Auxin Transport Inhibitors: IV. EVIDENCE OF A COMMON MODE OF ACTION FOR A PROPOSED CLASS OF AUXIN TRANSPORT INHIBITORS: THE PHYTOTROPINS." Plant physiology vol. 66,6 (1980): 1190-5. doi: https://doi.org/10.1104/pp.66.6.1190
Katekar GF, Geissler AE. Auxin Transport Inhibitors: IV. EVIDENCE OF A COMMON MODE OF ACTION FOR A PROPOSED CLASS OF AUXIN TRANSPORT INHIBITORS: THE PHYTOTROPINS. Plant Physiol. 1980 Dec;66(6):1190-5. doi: 10.1104/pp.66.6.1190. PMID: 16661601; PMCID: PMC440814.
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Showing 1 to 12 of 197 entries