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Showing 1 to 12 of 388 entries
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Current role of surgery in the treatment of digestive fistulas.

Annali italiani di chirurgia

Cozzaglio L, Farinella E, Coladonato M, Sciannameo F, Gennari L, Doci R.
PMID: 21319701
Ann Ital Chir. 2010 Jul-Aug;81(4):285-94.

UNLABELLED: Surgery is the main treatment of digestive fistulas (DF) but its role has changed over the last 40 years. The aim of this review is to analyze the surgical management of DF paying attention to timing and type...

Riding the Wave of Monodentate Ligand Revival: From the A/B Concept to Noncovalent Interactions.

Chemical record (New York, N.Y.)

Pignataro L, Gennari C.
PMID: 27424817
Chem Rec. 2016 Dec;16(6):2544-2560. doi: 10.1002/tcr.201600087. Epub 2016 Jul 18.

The rediscovery of chiral monodentate ligands made in the period 1999-2003 had important consequences in enantioselective transition-metal catalysis, such as the introduction of the A/B concept (i.e., use of monodentate ligand mixtures) and, later, a renewed interest in supramolecular...

The Role of Polyphenoloxidase, Peroxidase, and β-Glucosidase in Phenolics Accumulation in .

Frontiers in plant science

Cirilli M, Caruso G, Gennai C, Urbani S, Frioni E, Ruzzi M, Servili M, Gucci R, Poerio E, Muleo R.
PMID: 28536589
Front Plant Sci. 2017 May 09;8:717. doi: 10.3389/fpls.2017.00717. eCollection 2017.

Olive fruits and oils contain an array of compounds that contribute to their sensory and nutritional properties. Phenolic compounds in virgin oil and olive-derived products have been proven to be highly beneficial for human health, eliciting increasing attention from...

Adherence to Oral Anticancer Medications: Evolving Interprofessional Roles and Pharmacist Workforce Considerations.

Pharmacy (Basel, Switzerland)

Paolella GA, Boyd AD, Wirth SM, Cuellar S, Venepalli NK, Crawford SY.
PMID: 29518017
Pharmacy (Basel). 2018 Mar 08;6(1). doi: 10.3390/pharmacy6010023.

Interprofessional care is exhibited in outpatient oncology practices where practitioners from a myriad of specialties (e.g., oncology, nursing, pharmacy, health informatics and others) work collectively with patients to enhance therapeutic outcomes and minimize adverse effects. Historically, most ambulatory-based anticancer...

Synthesis and biological evaluation of RGD and isoDGR peptidomimetic-α-amanitin conjugates for tumor-targeting.

Beilstein journal of organic chemistry

Bodero L, López Rivas P, Korsak B, Hechler T, Pahl A, Müller C, Arosio D, Pignataro L, Gennari C, Piarulli U.
PMID: 29520305
Beilstein J Org Chem. 2018 Feb 14;14:407-415. doi: 10.3762/bjoc.14.29. eCollection 2018.

RGD-α-amanitin and isoDGR-α-amanitin conjugates were synthesized by joining integrin ligands to α-amanitin via various linkers and spacers. The conjugates were evaluated for their ability to inhibit biotinylated vitronectin binding to the purified α

An Experimental and Theoretical Investigation on Pentacoordinated Cobalt(III) Complexes with an Intermediate S=1 Spin State: How Halide Ligands Affect their Magnetic Anisotropy.

Chemistry (Weinheim an der Bergstrasse, Germany)

Brazzolotto D, Gennari M, Yu S, Pécaut J, Rouzières M, Clérac R, Orio M, Duboc C.
PMID: 26607991
Chemistry. 2016 Jan 18;22(3):925-33. doi: 10.1002/chem.201502997. Epub 2015 Nov 26.

Understanding the factors that control the magnitude and symmetry of magnetic anisotropy should facilitate the rational design of mononuclear metal complexes in the quest for single-molecule magnets (SMMs), based on a single metal ion, with high blocking temperatures and...

Ontogenetic changes of the soluble and membrane-bound D2 glycoprotein in rat forebrain.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience

Gennarini G, Corsi P, Pavia R, Vitiello F, Di Benedetta C.
PMID: 24873953
Int J Dev Neurosci. 1984;2(2):103-11. doi: 10.1016/0736-5748(84)90001-7.

A soluble form of the D2 glycoprotein, detected in the rat brain hypotonic extract, is described. Its specific relative concentration did not differ significantly in the three examined cerebral regions (forebrain, brainstem and cerebellum), while in the cerebellum the...

Dioxygen Activation and Catalytic Reduction to Hydrogen Peroxide by a Thiolate-Bridged Dimanganese(II) Complex with a Pendant Thiol.

Journal of the American Chemical Society

Gennari M, Brazzolotto D, Pécaut J, Cherrier MV, Pollock CJ, DeBeer S, Retegan M, Pantazis DA, Neese F, Rouzières M, Clérac R, Duboc C.
PMID: 26076066
J Am Chem Soc. 2015 Jul 08;137(26):8644-53. doi: 10.1021/jacs.5b04917. Epub 2015 Jun 29.

Herein, we describe an uncommon example of a manganese-thiolate complex, which is capable of activating dioxygen and catalyzing its two-electron reduction to generate H2O2. The structurally characterized dimercapto-bridged Mn(II) dimer [Mn(II)2(LS)(LSH)]ClO4 (Mn(II)2SH) is formed by reaction of the LS...

Asymmetric Hydrogenation of 3-Substituted Pyridinium Salts.

Chemistry (Weinheim an der Bergstrasse, Germany)

Renom-Carrasco M, Gajewski P, Pignataro L, de Vries JG, Piarulli U, Gennari C, Lefort L.
PMID: 27140832
Chemistry. 2016 Jul 04;22(28):9528-32. doi: 10.1002/chem.201601501. Epub 2016 Jun 03.

The use of an equivalent amount of an organic base leads to high enantiomeric excess in the asymmetric hydrogenation of N-benzylated 3-substituted pyridinium salts into the corresponding piperidines. Indeed, in the presence of Et3 N, a Rh-JosiPhos catalyst reduced...

Investigating the Interaction of Cyclic RGD Peptidomimetics with α.

Cancers

Civera M, Arosio D, Bonato F, Manzoni L, Pignataro L, Zanella S, Gennari C, Piarulli U, Belvisi L.
PMID: 28934103
Cancers (Basel). 2017 Sep 21;9(10). doi: 10.3390/cancers9100128.

The interaction of a small library of cyclic RGD (Arg-Gly-Asp) peptidomimetics with α

Endocrine actions of osteocalcin.

International journal of endocrinology

Patti A, Gennari L, Merlotti D, Dotta F, Nuti R.
PMID: 23737779
Int J Endocrinol. 2013;2013:846480. doi: 10.1155/2013/846480. Epub 2013 Apr 30.

Osteocalcin is the most abundant noncollagenous protein of bone matrix. Once transcribed, this protein undergoes posttranslational modifications within osteoblastic cells before its secretion, including the carboxylation of three glutamic residues in glutamic acid, which is essential for hydroxyapatite binding...

Viruses, stemness, embryogenesis, and cancer: a miracle leap toward molecular definition of novel oncotargets for therapy-resistant malignant tumors?.

Oncoscience

Glinsky GV.
PMID: 26501080
Oncoscience. 2015 Sep 12;2(9):751-4. doi: 10.18632/oncoscience.237. eCollection 2015.

Recent breakthrough studies documented consistent activation of specific endogenous retroviruses in human embryonic stem cells and preimplantation human embryos and demonstrated the essential role of the sustained retroviral activities for maintenance of pluripotency and embryonic stem cell identity. Present...

Showing 1 to 12 of 388 entries