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Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery.

Frontiers in pharmacology

Imbrici P, Liantonio A, Camerino GM, De Bellis M, Camerino C, Mele A, Giustino A, Pierno S, De Luca A, Tricarico D, Desaphy JF, Conte D.
PMID: 27242528
Front Pharmacol. 2016 May 10;7:121. doi: 10.3389/fphar.2016.00121. eCollection 2016.

In the human genome more than 400 genes encode ion channels, which are transmembrane proteins mediating ion fluxes across membranes. Being expressed in all cell types, they are involved in almost all physiological processes, including sense perception, neurotransmission, muscle...

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Imbrici P, Liantonio A, Camerino GM, et al. Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery. Front Pharmacol. 2016;7:121doi: 10.3389/fphar.2016.00121.
Imbrici, P., Liantonio, A., Camerino, G. M., De Bellis, M., Camerino, C., Mele, A., Giustino, A., Pierno, S., De Luca, A., Tricarico, D., Desaphy, J. F., & Conte, D. (2016). Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery. Frontiers in pharmacology, 7121. https://doi.org/10.3389/fphar.2016.00121
Imbrici, Paola, et al. "Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery." Frontiers in pharmacology vol. 7 (2016): 121. doi: https://doi.org/10.3389/fphar.2016.00121
Imbrici P, Liantonio A, Camerino GM, De Bellis M, Camerino C, Mele A, Giustino A, Pierno S, De Luca A, Tricarico D, Desaphy JF, Conte D. Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery. Front Pharmacol. 2016 May 10;7:121. doi: 10.3389/fphar.2016.00121. eCollection 2016. PMID: 27242528; PMCID: PMC4861771.
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Tramadol Extended-Release for the Management of Pain due to Osteoarthritis.

ISRN Pain

Angeletti C, Guetti C, Paladini A, Varrassi G.
PMID: 27335872
ISRN Pain. 2013 Sep 04;2013:245346. doi: 10.1155/2013/245346. eCollection 2013.

Current knowledge on pathogenesis of osteoarticular pain, as well as the consequent several, especially on the gastrointestinal, renal, and cardiovascular systems, side effects of NSAIDs, makes it difficult to perform an optimal management of this mixed typology of pain....

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Angeletti C, Guetti C, Paladini A, et al. Tramadol Extended-Release for the Management of Pain due to Osteoarthritis. ISRN Pain. 2013;2013:245346doi: 10.1155/2013/245346.
Angeletti, C., Guetti, C., Paladini, A., & Varrassi, G. (2013). Tramadol Extended-Release for the Management of Pain due to Osteoarthritis. ISRN Pain, 2013245346. https://doi.org/10.1155/2013/245346
Angeletti, Chiara, et al. "Tramadol Extended-Release for the Management of Pain due to Osteoarthritis." ISRN Pain vol. 2013 (2013): 245346. doi: https://doi.org/10.1155/2013/245346
Angeletti C, Guetti C, Paladini A, Varrassi G. Tramadol Extended-Release for the Management of Pain due to Osteoarthritis. ISRN Pain. 2013 Sep 04;2013:245346. doi: 10.1155/2013/245346. eCollection 2013. PMID: 27335872; PMCID: PMC4893407.
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Erratum to: Is cognitive stability in Parkinson's disease a predictable phenomenon? A 5-year follow-up study.

Journal of neural transmission (Vienna, Austria : 1996)

Di Battista ME, Rubino A, Valente M, Giustini P, Vanacore N, Meco G.
PMID: 26546036
J Neural Transm (Vienna). 2015 Dec;122(12):1707. doi: 10.1007/s00702-015-1474-5.

No abstract available.

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Di Battista ME, Rubino A, Valente M, et al. Erratum to: Is cognitive stability in Parkinson's disease a predictable phenomenon? A 5-year follow-up study. J Neural Transm (Vienna). 2015;122(12):1707doi: 10.1007/s00702-015-1474-5.
Di Battista, M. E., Rubino, A., Valente, M., Giustini, P., Vanacore, N., & Meco, G. (2015). Erratum to: Is cognitive stability in Parkinson's disease a predictable phenomenon? A 5-year follow-up study. Journal of neural transmission (Vienna, Austria : 1996), 122(12), 1707. https://doi.org/10.1007/s00702-015-1474-5
Di Battista, Maria Elena, et al. "Erratum to: Is cognitive stability in Parkinson's disease a predictable phenomenon? A 5-year follow-up study." Journal of neural transmission (Vienna, Austria : 1996) vol. 122,12 (2015): 1707. doi: https://doi.org/10.1007/s00702-015-1474-5
Di Battista ME, Rubino A, Valente M, Giustini P, Vanacore N, Meco G. Erratum to: Is cognitive stability in Parkinson's disease a predictable phenomenon? A 5-year follow-up study. J Neural Transm (Vienna). 2015 Dec;122(12):1707. doi: 10.1007/s00702-015-1474-5. PMID: 26546036.
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Stochastic Approach to Phonon-Assisted Optical Absorption.

Physical review letters

Zacharias M, Patrick CE, Giustino F.
PMID: 26551142
Phys Rev Lett. 2015 Oct 23;115(17):177401. doi: 10.1103/PhysRevLett.115.177401. Epub 2015 Oct 19.

We develop a first-principles theory of phonon-assisted optical absorption in semiconductors and insulators which incorporates the temperature dependence of the electronic structure. We show that the Hall-Bardeen-Blatt theory of indirect optical absorption and the Allen-Heine theory of temperature-dependent band...

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Zacharias M, Patrick CE, Giustino F. Stochastic Approach to Phonon-Assisted Optical Absorption. Phys Rev Lett. 2015;115(17):177401doi: 10.1103/PhysRevLett.115.177401.
Zacharias, M., Patrick, C. E., & Giustino, F. (2015). Stochastic Approach to Phonon-Assisted Optical Absorption. Physical review letters, 115(17), 177401. https://doi.org/10.1103/PhysRevLett.115.177401
Zacharias, Marios, et al. "Stochastic Approach to Phonon-Assisted Optical Absorption." Physical review letters vol. 115,17 (2015): 177401. doi: https://doi.org/10.1103/PhysRevLett.115.177401
Zacharias M, Patrick CE, Giustino F. Stochastic Approach to Phonon-Assisted Optical Absorption. Phys Rev Lett. 2015 Oct 23;115(17):177401. doi: 10.1103/PhysRevLett.115.177401. Epub 2015 Oct 19. PMID: 26551142.
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Modulation of Tryptophan/Serotonin Pathway by Probiotic Supplementation in Human Immunodeficiency Virus-Positive Patients: Preliminary Results of a New Study Approach.

International journal of tryptophan research : IJTR

Scheri GC, Fard SN, Schietroma I, Mastrangelo A, Pinacchio C, Giustini N, Serafino S, De Girolamo G, Cavallari EN, Statzu M, Laghi L, Vullo A, Ceccarelli G, Vullo V, d'Ettorre G.
PMID: 28607543
Int J Tryptophan Res. 2017 May 30;10:1178646917710668. doi: 10.1177/1178646917710668. eCollection 2017.

BACKGROUND: To date, no data are available regarding the effects of probiotics on the pathway of tryptophan/serotonin metabolism among human immunodeficiency virus (HIV) 1-infected individuals. Because a condition of dysbiosis might be responsible for the altered use of tryptophan...

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Scheri GC, Fard SN, Schietroma I, et al. Modulation of Tryptophan/Serotonin Pathway by Probiotic Supplementation in Human Immunodeficiency Virus-Positive Patients: Preliminary Results of a New Study Approach. Int J Tryptophan Res. 2017;10:1178646917710668doi: 10.1177/1178646917710668.
Scheri, G. C., Fard, S. N., Schietroma, I., Mastrangelo, A., Pinacchio, C., Giustini, N., Serafino, S., De Girolamo, G., Cavallari, E. N., Statzu, M., Laghi, L., Vullo, A., Ceccarelli, G., Vullo, V., & d'Ettorre, G. (2017). Modulation of Tryptophan/Serotonin Pathway by Probiotic Supplementation in Human Immunodeficiency Virus-Positive Patients: Preliminary Results of a New Study Approach. International journal of tryptophan research : IJTR, 101178646917710668. https://doi.org/10.1177/1178646917710668
Scheri, Giuseppe Corano, et al. "Modulation of Tryptophan/Serotonin Pathway by Probiotic Supplementation in Human Immunodeficiency Virus-Positive Patients: Preliminary Results of a New Study Approach." International journal of tryptophan research : IJTR vol. 10 (2017): 1178646917710668. doi: https://doi.org/10.1177/1178646917710668
Scheri GC, Fard SN, Schietroma I, Mastrangelo A, Pinacchio C, Giustini N, Serafino S, De Girolamo G, Cavallari EN, Statzu M, Laghi L, Vullo A, Ceccarelli G, Vullo V, d'Ettorre G. Modulation of Tryptophan/Serotonin Pathway by Probiotic Supplementation in Human Immunodeficiency Virus-Positive Patients: Preliminary Results of a New Study Approach. Int J Tryptophan Res. 2017 May 30;10:1178646917710668. doi: 10.1177/1178646917710668. eCollection 2017. PMID: 28607543; PMCID: PMC5457170.
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Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis.

Pain and therapy

Zis P, Paladini A, Piroli A, McHugh PC, Varrassi G, Hadjivassiliou M.
PMID: 28669085
Pain Ther. 2017 Dec;6(2):143-151. doi: 10.1007/s40122-017-0076-3. Epub 2017 Jul 01.

INTRODUCTION: Paraneoplastic neurological syndromes (PNS) consist of a heterogeneous group of neurological disorders triggered by cancer. The aim of this systematic review is to estimate the reported prevalence of pain in patients with paraneoplastic peripheral neuropathy (PPN).METHODS: A systematic...

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Zis P, Paladini A, Piroli A, et al. Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis. Pain Ther. 2017;6(2):143-151doi: 10.1007/s40122-017-0076-3.
Zis, P., Paladini, A., Piroli, A., McHugh, P. C., Varrassi, G., & Hadjivassiliou, M. (2017). Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis. Pain and therapy, 6(2), 143-151. https://doi.org/10.1007/s40122-017-0076-3
Zis, Panagiotis, et al. "Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis." Pain and therapy vol. 6,2 (2017): 143-151. doi: https://doi.org/10.1007/s40122-017-0076-3
Zis P, Paladini A, Piroli A, McHugh PC, Varrassi G, Hadjivassiliou M. Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis. Pain Ther. 2017 Dec;6(2):143-151. doi: 10.1007/s40122-017-0076-3. Epub 2017 Jul 01. PMID: 28669085; PMCID: PMC5693807.
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Optimal medical treatment: is it the worst option in multivessel coronary disease? Response.

Revista espanola de cardiologia (English ed.)

Buchanan GL, Giustino G, Chieffo A.
PMID: 25457089
Rev Esp Cardiol (Engl Ed). 2014 Dec;67(12):1075. doi: 10.1016/j.rec.2014.08.008. Epub 2014 Nov 07.

No abstract available.

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Buchanan GL, Giustino G, Chieffo A. Optimal medical treatment: is it the worst option in multivessel coronary disease? Response. Rev Esp Cardiol (Engl Ed). 2014;67(12):1075doi: 10.1016/j.rec.2014.08.008.
Buchanan, G. L., Giustino, G., & Chieffo, A. (2014). Optimal medical treatment: is it the worst option in multivessel coronary disease? Response. Revista espanola de cardiologia (English ed.), 67(12), 1075. https://doi.org/10.1016/j.rec.2014.08.008
Buchanan, Gill Louise, et al. "Optimal medical treatment: is it the worst option in multivessel coronary disease? Response." Revista espanola de cardiologia (English ed.) vol. 67,12 (2014): 1075. doi: https://doi.org/10.1016/j.rec.2014.08.008
Buchanan GL, Giustino G, Chieffo A. Optimal medical treatment: is it the worst option in multivessel coronary disease? Response. Rev Esp Cardiol (Engl Ed). 2014 Dec;67(12):1075. doi: 10.1016/j.rec.2014.08.008. Epub 2014 Nov 07. PMID: 25457089.
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Risk stratification of patients undergoing medical therapy after coronary angiography.

European heart journal

Bettinger N, Palmerini T, Caixeta A, Dressler O, Litherland C, Francese DP, Giustino G, Mehran R, Leon MB, Stone GW, Généreux P.
PMID: 26685136
Eur Heart J. 2016 Oct 21;37(40):3103-3110. doi: 10.1093/eurheartj/ehv674. Epub 2015 Dec 18.

AIM: We sought to investigate the prognostic impact of the SYNTAX (Synergy between PCI with TAXUS and Cardiac Surgery) score (SS) on 1-year clinical outcomes in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS) undergoing medical therapy only.METHODS...

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Bettinger N, Palmerini T, Caixeta A, et al. Risk stratification of patients undergoing medical therapy after coronary angiography. Eur Heart J. 2015;37(40):3103-3110doi: 10.1093/eurheartj/ehv674.
Bettinger, N., Palmerini, T., Caixeta, A., Dressler, O., Litherland, C., Francese, D. P., Giustino, G., Mehran, R., Leon, M. B., Stone, G. W., & Généreux, P. (2016). Risk stratification of patients undergoing medical therapy after coronary angiography. European heart journal, 37(40), 3103-3110. https://doi.org/10.1093/eurheartj/ehv674
Bettinger, Nicolas, et al. "Risk stratification of patients undergoing medical therapy after coronary angiography." European heart journal vol. 37,40 (2016): 3103-3110. doi: https://doi.org/10.1093/eurheartj/ehv674
Bettinger N, Palmerini T, Caixeta A, Dressler O, Litherland C, Francese DP, Giustino G, Mehran R, Leon MB, Stone GW, Généreux P. Risk stratification of patients undergoing medical therapy after coronary angiography. Eur Heart J. 2016 Oct 21;37(40):3103-3110. doi: 10.1093/eurheartj/ehv674. Epub 2015 Dec 18. PMID: 26685136.
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Parathyroid hormone pulsatility: physiological and clinical aspects.

Bone research

Chiavistelli S, Giustina A, Mazziotti G.
PMID: 26273533
Bone Res. 2015 Jan 27;3:14049. doi: 10.1038/boneres.2014.49. eCollection 2015.

Parathyroid hormone (PTH) secretion is characterized by an ultradian rhythm with tonic and pulsatile components. In healthy subjects, the majority of PTH is secreted in tonic fashion, whereas approximately 30% is secreted in low-amplitude and high-frequency bursts occurring every...

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Chiavistelli S, Giustina A, Mazziotti G. Parathyroid hormone pulsatility: physiological and clinical aspects. Bone Res. 2015;3:14049doi: 10.1038/boneres.2014.49.
Chiavistelli, S., Giustina, A., & Mazziotti, G. (2015). Parathyroid hormone pulsatility: physiological and clinical aspects. Bone research, 314049. https://doi.org/10.1038/boneres.2014.49
Chiavistelli, Silvia, et al. "Parathyroid hormone pulsatility: physiological and clinical aspects." Bone research vol. 3 (2015): 14049. doi: https://doi.org/10.1038/boneres.2014.49
Chiavistelli S, Giustina A, Mazziotti G. Parathyroid hormone pulsatility: physiological and clinical aspects. Bone Res. 2015 Jan 27;3:14049. doi: 10.1038/boneres.2014.49. eCollection 2015. PMID: 26273533; PMCID: PMC4472146.
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Decision making between percutaneous coronary intervention or bypass surgery in multi-vessel coronary disease.

Revista espanola de cardiologia (English ed.)

Buchanan GL, Giustino G, Chieffo A.
PMID: 24863589
Rev Esp Cardiol (Engl Ed). 2014 Jun;67(6):428-31. doi: 10.1016/j.rec.2013.08.017. Epub 2013 Dec 21.

No abstract available.

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Buchanan GL, Giustino G, Chieffo A. Decision making between percutaneous coronary intervention or bypass surgery in multi-vessel coronary disease. Rev Esp Cardiol (Engl Ed). 2013;67(6):428-31doi: 10.1016/j.rec.2013.08.017.
Buchanan, G. L., Giustino, G., & Chieffo, A. (2014). Decision making between percutaneous coronary intervention or bypass surgery in multi-vessel coronary disease. Revista espanola de cardiologia (English ed.), 67(6), 428-31. https://doi.org/10.1016/j.rec.2013.08.017
Buchanan, Gill Louise, et al. "Decision making between percutaneous coronary intervention or bypass surgery in multi-vessel coronary disease." Revista espanola de cardiologia (English ed.) vol. 67,6 (2014): 428-31. doi: https://doi.org/10.1016/j.rec.2013.08.017
Buchanan GL, Giustino G, Chieffo A. Decision making between percutaneous coronary intervention or bypass surgery in multi-vessel coronary disease. Rev Esp Cardiol (Engl Ed). 2014 Jun;67(6):428-31. doi: 10.1016/j.rec.2013.08.017. Epub 2013 Dec 21. PMID: 24863589.
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XVI(th) QTLMAS: simulated dataset and comparative analysis of submitted results for QTL mapping and genomic evaluation.

BMC proceedings

Usai MG, Gaspa G, Macciotta NP, Carta A, Casu S.
PMID: 25519515
BMC Proc. 2014 Oct 07;8:S1. doi: 10.1186/1753-6561-8-S5-S1. eCollection 2014.

BACKGROUND: A common dataset was simulated and made available to participants of the XVI(th) QTL-MAS workshop. Tasks for the participants were to detect QTLs affecting three traits, to assess their possible pleiotropic effects, and to evaluate the breeding values...

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Usai MG, Gaspa G, Macciotta NP, et al. XVI(th) QTLMAS: simulated dataset and comparative analysis of submitted results for QTL mapping and genomic evaluation. BMC Proc. 2014;8:S1doi: 10.1186/1753-6561-8-S5-S1.
Usai, M. G., Gaspa, G., Macciotta, N. P., Carta, A., & Casu, S. (2014). XVI(th) QTLMAS: simulated dataset and comparative analysis of submitted results for QTL mapping and genomic evaluation. BMC proceedings, 8S1. https://doi.org/10.1186/1753-6561-8-S5-S1
Usai, M Graziano, et al. "XVI(th) QTLMAS: simulated dataset and comparative analysis of submitted results for QTL mapping and genomic evaluation." BMC proceedings vol. 8 (2014): S1. doi: https://doi.org/10.1186/1753-6561-8-S5-S1
Usai MG, Gaspa G, Macciotta NP, Carta A, Casu S. XVI(th) QTLMAS: simulated dataset and comparative analysis of submitted results for QTL mapping and genomic evaluation. BMC Proc. 2014 Oct 07;8:S1. doi: 10.1186/1753-6561-8-S5-S1. eCollection 2014. PMID: 25519515; PMCID: PMC4195410.
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Infrared spectra at surfaces and interfaces from first principles: evolution of the spectra across the Si(100)-SiO2 interface.

Physical review letters

Giustino F, Pasquarello A.
PMID: 16383945
Phys Rev Lett. 2005 Oct 28;95(18):187402. doi: 10.1103/PhysRevLett.95.187402. Epub 2005 Oct 25.

We introduce a general scheme for calculating from first principles both the transverse-optical and longitudinal-optical infrared absorption spectra at surfaces or interfaces. A spatial decomposition of the spectra gives the evolution of the infrared activity across the considered system....

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Giustino F, Pasquarello A. Infrared spectra at surfaces and interfaces from first principles: evolution of the spectra across the Si(100)-SiO2 interface. Phys Rev Lett. 2005;95(18):187402doi: 10.1103/PhysRevLett.95.187402.
Giustino, F., & Pasquarello, A. (2005). Infrared spectra at surfaces and interfaces from first principles: evolution of the spectra across the Si(100)-SiO2 interface. Physical review letters, 95(18), 187402. https://doi.org/10.1103/PhysRevLett.95.187402
Giustino, Feliciano, and Pasquarello, Alfredo. "Infrared spectra at surfaces and interfaces from first principles: evolution of the spectra across the Si(100)-SiO2 interface." Physical review letters vol. 95,18 (2005): 187402. doi: https://doi.org/10.1103/PhysRevLett.95.187402
Giustino F, Pasquarello A. Infrared spectra at surfaces and interfaces from first principles: evolution of the spectra across the Si(100)-SiO2 interface. Phys Rev Lett. 2005 Oct 28;95(18):187402. doi: 10.1103/PhysRevLett.95.187402. Epub 2005 Oct 25. PMID: 16383945.
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Showing 1 to 12 of 517 entries