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Showing 1 to 12 of 37 entries
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Mammaglobin-A is a target for breast cancer vaccination.

Oncoimmunology

Kim SW, Goedegebuure P, Gillanders WE.
PMID: 27057470
Oncoimmunology. 2016 Feb 26;5(2):e1069940. doi: 10.1080/2162402X.2015.1069940. eCollection 2016 Feb.

We recently completed a phase 1 clinical trial demonstrating the safety of a mammaglobin-A DNA vaccine in patients with metastatic breast cancer. We are currently enrolling patients with early stage breast cancer in a phase 1b clinical trial. The...

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Kim SW, Goedegebuure P, Gillanders WE. Mammaglobin-A is a target for breast cancer vaccination. Oncoimmunology. 2016;5(2):e1069940doi: 10.1080/2162402X.2015.1069940.
Kim, S. W., Goedegebuure, P., & Gillanders, W. E. (2016). Mammaglobin-A is a target for breast cancer vaccination. Oncoimmunology, 5(2), e1069940. https://doi.org/10.1080/2162402X.2015.1069940
Kim, Samuel W, et al. "Mammaglobin-A is a target for breast cancer vaccination." Oncoimmunology vol. 5,2 (2016): e1069940. doi: https://doi.org/10.1080/2162402X.2015.1069940
Kim SW, Goedegebuure P, Gillanders WE. Mammaglobin-A is a target for breast cancer vaccination. Oncoimmunology. 2016 Feb 26;5(2):e1069940. doi: 10.1080/2162402X.2015.1069940. eCollection 2016 Feb. PMID: 27057470; PMCID: PMC4801441.
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Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene.

Nature communications

van Ingen G, Li J, Goedegebure A, Pandey R, Li YR, March ME, Jaddoe VW, Bakay M, Mentch FD, Thomas K, Wei Z, Chang X, Hain HS, Uitterlinden AG, Moll HA, van Duijn CM, Rivadeneira F, Raat H, Baatenburg de Jong RJ, Sleiman PM, van der Schroeff MP, Hakonarson H.
PMID: 27677580
Nat Commun. 2016 Sep 28;7:12792. doi: 10.1038/ncomms12792.

Acute otitis media (AOM) is among the most common pediatric diseases, and the most frequent reason for antibiotic treatment in children. Risk of AOM is dependent on environmental and host factors, as well as a significant genetic component. We...

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van Ingen G, Li J, Goedegebure A, et al. Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene. Nat Commun. 2016;7:12792doi: 10.1038/ncomms12792.
van Ingen, G., Li, J., Goedegebure, A., Pandey, R., Li, Y. R., March, M. E., Jaddoe, V. W., Bakay, M., Mentch, F. D., Thomas, K., Wei, Z., Chang, X., Hain, H. S., Uitterlinden, A. G., Moll, H. A., van Duijn, C. M., Rivadeneira, F., Raat, H., Baatenburg de Jong, R. J., Sleiman, P. M., van der Schroeff, M. P., & Hakonarson, H. (2016). Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene. Nature communications, 712792. https://doi.org/10.1038/ncomms12792
van Ingen, Gijs, et al. "Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene." Nature communications vol. 7 (2016): 12792. doi: https://doi.org/10.1038/ncomms12792
van Ingen G, Li J, Goedegebure A, Pandey R, Li YR, March ME, Jaddoe VW, Bakay M, Mentch FD, Thomas K, Wei Z, Chang X, Hain HS, Uitterlinden AG, Moll HA, van Duijn CM, Rivadeneira F, Raat H, Baatenburg de Jong RJ, Sleiman PM, van der Schroeff MP, Hakonarson H. Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene. Nat Commun. 2016 Sep 28;7:12792. doi: 10.1038/ncomms12792. PMID: 27677580; PMCID: PMC5052699.
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Type of Speech Material Affects Acceptable Noise Level Test Outcome.

Frontiers in psychology

Koch X, Dingemanse G, Goedegebure A, Janse E.
PMID: 26952145
Front Psychol. 2016 Feb 26;7:186. doi: 10.3389/fpsyg.2016.00186. eCollection 2016.

The acceptable noise level (ANL) test, in which individuals indicate what level of noise they are willing to put up with while following speech, has been used to guide hearing aid fitting decisions and has been found to relate...

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Koch X, Dingemanse G, Goedegebure A, et al. Type of Speech Material Affects Acceptable Noise Level Test Outcome. Front Psychol. 2016;7:186doi: 10.3389/fpsyg.2016.00186.
Koch, X., Dingemanse, G., Goedegebure, A., & Janse, E. (2016). Type of Speech Material Affects Acceptable Noise Level Test Outcome. Frontiers in psychology, 7186. https://doi.org/10.3389/fpsyg.2016.00186
Koch, Xaver, et al. "Type of Speech Material Affects Acceptable Noise Level Test Outcome." Frontiers in psychology vol. 7 (2016): 186. doi: https://doi.org/10.3389/fpsyg.2016.00186
Koch X, Dingemanse G, Goedegebure A, Janse E. Type of Speech Material Affects Acceptable Noise Level Test Outcome. Front Psychol. 2016 Feb 26;7:186. doi: 10.3389/fpsyg.2016.00186. eCollection 2016. PMID: 26952145; PMCID: PMC4767928.
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Vaccine Trials for the Clinician: Prospects for Viral and Non-Viral Vectors.

The oncologist

Goedegebuure PS, Eberlein TJ.
PMID: 10388062
Oncologist. 1997;2(5):300-310.

Recent progress in tumor genetics, tumor biology, and tumor immunology has renewed interest in the development of tumor vaccines. Unlike the previous generation of vaccines that consisted of the patient's own tumor cells in some form, the new vaccines...

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Goedegebuure PS, Eberlein TJ. Vaccine Trials for the Clinician: Prospects for Viral and Non-Viral Vectors. Oncologist. 1997;2(5):300-310
Goedegebuure, P. S., & Eberlein, T. J. (1997). Vaccine Trials for the Clinician: Prospects for Viral and Non-Viral Vectors. The oncologist, 2(5), 300-310.
Goedegebuure, and Eberlein. "Vaccine Trials for the Clinician: Prospects for Viral and Non-Viral Vectors." The oncologist vol. 2,5 (1997): 300-310.
Goedegebuure PS, Eberlein TJ. Vaccine Trials for the Clinician: Prospects for Viral and Non-Viral Vectors. Oncologist. 1997;2(5):300-310. PMID: 10388062.
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The clonal evolution of metastatic colorectal cancer.

Science advances

Dang HX, Krasnick BA, White BS, Grossman JG, Strand MS, Zhang J, Cabanski CR, Miller CA, Fulton RS, Goedegebuure SP, Fronick CC, Griffith M, Larson DE, Goetz BD, Walker JR, Hawkins WG, Strasberg SM, Linehan DC, Lim KH, Lockhart AC, Mardis ER, Wilson RK, Ley TJ, Maher CA, Fields RC.
PMID: 32577507
Sci Adv. 2020 Jun 10;6(24):eaay9691. doi: 10.1126/sciadv.aay9691. eCollection 2020 Jun.

Tumor heterogeneity and evolution drive treatment resistance in metastatic colorectal cancer (mCRC). Patient-derived xenografts (PDXs) can model mCRC biology; however, their ability to accurately mimic human tumor heterogeneity is unclear. Current genomic studies in mCRC have limited scope and...

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Dang HX, Krasnick BA, White BS, et al. The clonal evolution of metastatic colorectal cancer. Sci Adv. 2020;6(24):eaay9691doi: 10.1126/sciadv.aay9691.
Dang, H. X., Krasnick, B. A., White, B. S., Grossman, J. G., Strand, M. S., Zhang, J., Cabanski, C. R., Miller, C. A., Fulton, R. S., Goedegebuure, S. P., Fronick, C. C., Griffith, M., Larson, D. E., Goetz, B. D., Walker, J. R., Hawkins, W. G., Strasberg, S. M., Linehan, D. C., Lim, K. H., Lockhart, A. C., Mardis, E. R., Wilson, R. K., Ley, T. J., Maher, C. A., & Fields, R. C. (2020). The clonal evolution of metastatic colorectal cancer. Science advances, 6(24), eaay9691. https://doi.org/10.1126/sciadv.aay9691
Dang, Ha X, et al. "The clonal evolution of metastatic colorectal cancer." Science advances vol. 6,24 (2020): eaay9691. doi: https://doi.org/10.1126/sciadv.aay9691
Dang HX, Krasnick BA, White BS, Grossman JG, Strand MS, Zhang J, Cabanski CR, Miller CA, Fulton RS, Goedegebuure SP, Fronick CC, Griffith M, Larson DE, Goetz BD, Walker JR, Hawkins WG, Strasberg SM, Linehan DC, Lim KH, Lockhart AC, Mardis ER, Wilson RK, Ley TJ, Maher CA, Fields RC. The clonal evolution of metastatic colorectal cancer. Sci Adv. 2020 Jun 10;6(24):eaay9691. doi: 10.1126/sciadv.aay9691. eCollection 2020 Jun. PMID: 32577507; PMCID: PMC7286679.
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Hearing Impairment Is Associated with Smaller Brain Volume in Aging.

Frontiers in aging neuroscience

Rigters SC, Bos D, Metselaar M, Roshchupkin GV, Baatenburg de Jong RJ, Ikram MA, Vernooij MW, Goedegebure A.
PMID: 28163683
Front Aging Neurosci. 2017 Jan 20;9:2. doi: 10.3389/fnagi.2017.00002. eCollection 2017.

Although recent studies show that age-related hearing impairment is associated with cerebral changes, data from a population perspective are still lacking. Therefore, we studied the relation between hearing impairment and brain volume in a large elderly cohort. From the...

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Rigters SC, Bos D, Metselaar M, et al. Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Front Aging Neurosci. 2017;9:2doi: 10.3389/fnagi.2017.00002.
Rigters, S. C., Bos, D., Metselaar, M., Roshchupkin, G. V., Baatenburg de Jong, R. J., Ikram, M. A., Vernooij, M. W., & Goedegebure, A. (2017). Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Frontiers in aging neuroscience, 92. https://doi.org/10.3389/fnagi.2017.00002
Rigters, Stephanie C, et al. "Hearing Impairment Is Associated with Smaller Brain Volume in Aging." Frontiers in aging neuroscience vol. 9 (2017): 2. doi: https://doi.org/10.3389/fnagi.2017.00002
Rigters SC, Bos D, Metselaar M, Roshchupkin GV, Baatenburg de Jong RJ, Ikram MA, Vernooij MW, Goedegebure A. Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Front Aging Neurosci. 2017 Jan 20;9:2. doi: 10.3389/fnagi.2017.00002. eCollection 2017. PMID: 28163683; PMCID: PMC5247429.
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Osteochondrosis in six breeds of slaughter pigs.

The veterinary quarterly

van der Wal PG, van der Valk PC, Goedegebuure SA, van Essen G.
PMID: 22039857
Vet Q. 1980 Jan;2(1):42-7. doi: 10.1080/01652176.1980.9693756.

Summary Coefficients of correlation have been calculated between morphological lesion scores of osteochondrosis that were made on the bones of porcine fore and hind limbs and some carcass characteristics. It was found that carcass length, as well as the...

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van der Wal PG, van der Valk PC, Goedegebuure SA, et al. Osteochondrosis in six breeds of slaughter pigs. Vet Q. 1980;2(1):42-7doi: 10.1080/01652176.1980.9693756.
van der Wal, P. G., van der Valk, P. C., Goedegebuure, S. A., & van Essen, G. (1980). Osteochondrosis in six breeds of slaughter pigs. The veterinary quarterly, 2(1), 42-7. https://doi.org/10.1080/01652176.1980.9693756
van der Wal, P G, et al. "Osteochondrosis in six breeds of slaughter pigs." The veterinary quarterly vol. 2,1 (1980): 42-7. doi: https://doi.org/10.1080/01652176.1980.9693756
van der Wal PG, van der Valk PC, Goedegebuure SA, van Essen G. Osteochondrosis in six breeds of slaughter pigs. Vet Q. 1980 Jan;2(1):42-7. doi: 10.1080/01652176.1980.9693756. PMID: 22039857.
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Corrigendum: Hearing Impairment Is Associated with Smaller Brain Volume in Aging.

Frontiers in aging neuroscience

Rigters SC, Bos D, Metselaar M, Roshchupkin GV, Baatenburg de Jong RJ, Ikram MA, Vernooij MW, Goedegebure A.
PMID: 28491034
Front Aging Neurosci. 2017 May 08;9:131. doi: 10.3389/fnagi.2017.00131. eCollection 2017.

[This corrects the article on p. 2 in vol. 9, PMID: 28163683.].

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Rigters SC, Bos D, Metselaar M, et al. Corrigendum: Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Front Aging Neurosci. 2017;9:131doi: 10.3389/fnagi.2017.00131.
Rigters, S. C., Bos, D., Metselaar, M., Roshchupkin, G. V., Baatenburg de Jong, R. J., Ikram, M. A., Vernooij, M. W., & Goedegebure, A. (2017). Corrigendum: Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Frontiers in aging neuroscience, 9131. https://doi.org/10.3389/fnagi.2017.00131
Rigters, Stephanie C, et al. "Corrigendum: Hearing Impairment Is Associated with Smaller Brain Volume in Aging." Frontiers in aging neuroscience vol. 9 (2017): 131. doi: https://doi.org/10.3389/fnagi.2017.00131
Rigters SC, Bos D, Metselaar M, Roshchupkin GV, Baatenburg de Jong RJ, Ikram MA, Vernooij MW, Goedegebure A. Corrigendum: Hearing Impairment Is Associated with Smaller Brain Volume in Aging. Front Aging Neurosci. 2017 May 08;9:131. doi: 10.3389/fnagi.2017.00131. eCollection 2017. PMID: 28491034; PMCID: PMC5420703.
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Are multidisciplinary neurodevelopmental profiles of children born very preterm at age 2 relevant to their long-term development? A preliminary study.

Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence

van Noort-van der Spek IL, Stipdonk LW, Goedegebure A, Dudink J, Willemsen S, Reiss IKM, Franken MJP.
PMID: 34727843
Child Neuropsychol. 2021 Nov 02;1-21. doi: 10.1080/09297049.2021.1991296. Epub 2021 Nov 02.

To identify distinctive multidisciplinary neurodevelopmental profiles of relatively healthy children born very preterm (VPT) and describe the longitudinal course of these profiles up to age 10. At 2 years of corrected age, 84 children born VPT underwent standardized testing...

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van Noort-van der Spek IL, Stipdonk LW, Goedegebure A, et al. Are multidisciplinary neurodevelopmental profiles of children born very preterm at age 2 relevant to their long-term development? A preliminary study. Child Neuropsychol. 2021;1-21doi: 10.1080/09297049.2021.1991296.
van Noort-van der Spek, I. L., Stipdonk, L. W., Goedegebure, A., Dudink, J., Willemsen, S., Reiss, I. K. M., & Franken, M. J. P. (2021). Are multidisciplinary neurodevelopmental profiles of children born very preterm at age 2 relevant to their long-term development? A preliminary study. Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence, 1-21. https://doi.org/10.1080/09297049.2021.1991296
van Noort-van der Spek, Inge L, et al. "Are multidisciplinary neurodevelopmental profiles of children born very preterm at age 2 relevant to their long-term development? A preliminary study." Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence vol. (2021): 1-21. doi: https://doi.org/10.1080/09297049.2021.1991296
van Noort-van der Spek IL, Stipdonk LW, Goedegebure A, Dudink J, Willemsen S, Reiss IKM, Franken MJP. Are multidisciplinary neurodevelopmental profiles of children born very preterm at age 2 relevant to their long-term development? A preliminary study. Child Neuropsychol. 2021 Nov 02;1-21. doi: 10.1080/09297049.2021.1991296. Epub 2021 Nov 02. PMID: 34727843.
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Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation.

Genome medicine

Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE.
PMID: 33879241
Genome Med. 2021 Apr 21;13(1):56. doi: 10.1186/s13073-021-00872-4.

BACKGROUND: Preclinical studies and early clinical trials have shown that targeting cancer neoantigens is a promising approach towards the development of personalized cancer immunotherapies. DNA vaccines can be rapidly and efficiently manufactured and can integrate multiple neoantigens simultaneously. We...

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Li L, Zhang X, Wang X, et al. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Med. 2021;13(1):56doi: 10.1186/s13073-021-00872-4.
Li, L., Zhang, X., Wang, X., Kim, S. W., Herndon, J. M., Becker-Hapak, M. K., Carreno, B. M., Myers, N. B., Sturmoski, M. A., McLellan, M. D., Miller, C. A., Johanns, T. M., Tan, B. R., Dunn, G. P., Fleming, T. P., Hansen, T. H., Goedegebuure, S. P., & Gillanders, W. E. (2021). Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome medicine, 13(1), 56. https://doi.org/10.1186/s13073-021-00872-4
Li, Lijin, et al. "Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation." Genome medicine vol. 13,1 (2021): 56. doi: https://doi.org/10.1186/s13073-021-00872-4
Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Med. 2021 Apr 21;13(1):56. doi: 10.1186/s13073-021-00872-4. PMID: 33879241; PMCID: PMC8059244.
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Memory-like Differentiation Enhances NK Cell Responses to Melanoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Marin ND, Krasnick BA, Becker-Hapak M, Conant L, Goedegebuure SP, Berrien-Elliott MM, Robbins KJ, Foltz JA, Foster M, Wong P, Cubitt CC, Tran J, Wetzel CB, Jacobs M, Zhou AY, Russler-Germain D, Marsala L, Schappe T, Fields RC, Fehniger TA.
PMID: 34187852
Clin Cancer Res. 2021 Sep 01;27(17):4859-4869. doi: 10.1158/1078-0432.CCR-21-0851. Epub 2021 Jun 29.

PURPOSE: Treatment of advanced melanoma is a clinical challenge. Natural killer (NK) cells are a promising cellular therapy for T cell-refractory cancers, but are frequently deficient or dysfunctional in patients with melanoma. Thus, new strategies are needed to enhance...

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Marin ND, Krasnick BA, Becker-Hapak M, et al. Memory-like Differentiation Enhances NK Cell Responses to Melanoma. Clin Cancer Res. 2021;27(17):4859-4869doi: 10.1158/1078-0432.CCR-21-0851.
Marin, N. D., Krasnick, B. A., Becker-Hapak, M., Conant, L., Goedegebuure, S. P., Berrien-Elliott, M. M., Robbins, K. J., Foltz, J. A., Foster, M., Wong, P., Cubitt, C. C., Tran, J., Wetzel, C. B., Jacobs, M., Zhou, A. Y., Russler-Germain, D., Marsala, L., Schappe, T., Fields, R. C., & Fehniger, T. A. (2021). Memory-like Differentiation Enhances NK Cell Responses to Melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 27(17), 4859-4869. https://doi.org/10.1158/1078-0432.CCR-21-0851
Marin, Nancy D, et al. "Memory-like Differentiation Enhances NK Cell Responses to Melanoma." Clinical cancer research : an official journal of the American Association for Cancer Research vol. 27,17 (2021): 4859-4869. doi: https://doi.org/10.1158/1078-0432.CCR-21-0851
Marin ND, Krasnick BA, Becker-Hapak M, Conant L, Goedegebuure SP, Berrien-Elliott MM, Robbins KJ, Foltz JA, Foster M, Wong P, Cubitt CC, Tran J, Wetzel CB, Jacobs M, Zhou AY, Russler-Germain D, Marsala L, Schappe T, Fields RC, Fehniger TA. Memory-like Differentiation Enhances NK Cell Responses to Melanoma. Clin Cancer Res. 2021 Sep 01;27(17):4859-4869. doi: 10.1158/1078-0432.CCR-21-0851. Epub 2021 Jun 29. PMID: 34187852; PMCID: PMC8416927.
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Challenges targeting cancer neoantigens in 2021: a systematic literature review.

Expert review of vaccines

Chen I, Chen MY, Goedegebuure SP, Gillanders WE.
PMID: 34047245
Expert Rev Vaccines. 2021 Jul;20(7):827-837. doi: 10.1080/14760584.2021.1935248. Epub 2021 Jun 09.

No abstract available.

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Chen I, Chen MY, Goedegebuure SP, et al. Challenges targeting cancer neoantigens in 2021: a systematic literature review. Expert Rev Vaccines. 2021;20(7):827-837doi: 10.1080/14760584.2021.1935248.
Chen, I., Chen, M. Y., Goedegebuure, S. P., & Gillanders, W. E. (2021). Challenges targeting cancer neoantigens in 2021: a systematic literature review. Expert review of vaccines, 20(7), 827-837. https://doi.org/10.1080/14760584.2021.1935248
Chen, Ina, et al. "Challenges targeting cancer neoantigens in 2021: a systematic literature review." Expert review of vaccines vol. 20,7 (2021): 827-837. doi: https://doi.org/10.1080/14760584.2021.1935248
Chen I, Chen MY, Goedegebuure SP, Gillanders WE. Challenges targeting cancer neoantigens in 2021: a systematic literature review. Expert Rev Vaccines. 2021 Jul;20(7):827-837. doi: 10.1080/14760584.2021.1935248. Epub 2021 Jun 09. PMID: 34047245; PMCID: PMC8410655.
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