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Showing 1 to 12 of 14 entries
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Redox-Triggered Helicity Inversion in Chiral Cobalt Complexes in Combination with H(+) and NO3(-) Stimuli.

Inorganic chemistry

Gregoliński J, Hikita M, Sakamoto T, Sugimoto H, Tsukube H, Miyake H.
PMID: 26731008
Inorg Chem. 2016 Jan 19;55(2):633-43. doi: 10.1021/acs.inorgchem.5b01902. Epub 2016 Jan 05.

Three chiral ligands with variable denticity, H2L2-H2L4, conjugated by N,N'-ethylenebis[N-methyl-(S)-alanine] and an ortho-heterosubstituted aromatic amine, were newly synthesized as analogues of previously reported H2L1. Four contracted-Λoxo cobalt(III) complexes [Co(L)](+) with left-handed helical structure of Λ4Δ2 configuration were prepared by...

Octulene: A Hyperbolic Molecular Belt that Binds Chloride Anions.

Angewandte Chemie (International ed. in English)

Majewski MA, Hong Y, Lis T, Gregoliński J, Chmielewski PJ, Cybińska J, Kim D, Stępień M.
PMID: 27709735
Angew Chem Int Ed Engl. 2016 Nov 02;55(45):14072-14076. doi: 10.1002/anie.201608384. Epub 2016 Oct 06.

Octulene, the higher homologue of kekulene and septulene, was synthesized using the fold-in method. This new hydrocarbon macrocycle contains a large 24-membered inner circuit, which is peripherally fused to 24 benzene rings. Such an arrangement produces considerable hyperbolic distortion...

Can high dose rates used in cancer radiotherapy change therapeutic effectiveness?.

Contemporary oncology (Poznan, Poland)

Konopacka M, Rogoliński J, Sochanik A, Ślosarek K.
PMID: 28239281
Contemp Oncol (Pozn). 2016;20(6):449-452. doi: 10.5114/wo.2016.65603. Epub 2017 Jan 12.

Current cancer radiotherapy relies on increasingly high dose rates of ionising radiation (100-2400 cGy/min). It is possible that changing dose rates is not paralleled by treatment effectiveness. Irradiating cancer cells is assumed to induce molecular alterations that ultimately lead...

Multinuclear Ni(ii), Cu(ii) and Zn(ii) complexes of chiral macrocyclic nonaazamine.

Dalton transactions (Cambridge, England : 2003)

Löffler M, Gregoliński J, Korabik M, Lis T, Lisowski J.
PMID: 27722347
Dalton Trans. 2016 Oct 04;45(39):15586-15594. doi: 10.1039/c6dt02504h.

The chiral macrocyclic amines R-L and S-L derived from the 3 + 3 condensation of 2,6-diformylpyridine and (1R,2R)-1,2-diaminocyclohexane or (1S,2S)-1,2-diaminocyclohexane form enantiopure trinuclear Ni(ii) and Cu(ii) complexes [Ni

Lanthanide(III) and lead(II) complexes of a chiral nonaaza macrocyclic amine based on 1,2-diaminocyclopentane.

Dalton transactions (Cambridge, England : 2003)

Gregoliński J, Ślepokura K, Lisowski J.
PMID: 26305600
Dalton Trans. 2015 Oct 07;44(37):16345-51. doi: 10.1039/c5dt02478a.

The macrocyclic nonaaza 3 + 3 amine based on diaminocyclopentane forms enantiopure helical complexes with lanthanide(III) ions. In contrast to analogous complexes based on 1,2-trans-diaminocyclohexane, no clear helicity process is observed. Crystal structures of these compounds show tight helical...

Helicity inversion in lanthanide(III) complexes with chiral nonaaza macrocyclic ligands.

Angewandte Chemie (International ed. in English)

Gregoliński J, Lisowski J.
PMID: 16921573
Angew Chem Int Ed Engl. 2006 Sep 18;45(37):6122-6. doi: 10.1002/anie.200602464.

No abstract available.

Stereoselective Wittig Olefination as a Macrocyclization Tool. Synthesis of Large Carbazolophanes.

The Journal of organic chemistry

Myśliwiec D, Lis T, Gregoliński J, Stępień M.
PMID: 25974254
J Org Chem. 2015 Jun 19;80(12):6300-12. doi: 10.1021/acs.joc.5b00745. Epub 2015 Jun 04.

Z-Selective Wittig olefination was applied to the synthesis of large carbazolophanes containing up to eight heteroaromatic subunits. A number of strategies were devised and tested, showing that cyclooligomerization yields can be significantly improved by using one-component schemes involving heterobifunctional...

Controlling chirality in the synthesis of 4 + 4 diastereomeric amine macrocycles derived from .

Organic & biomolecular chemistry

Fedorowicz D, Banach S, Koza P, Frydrych R, Ślepokura K, Gregoliński J.
PMID: 35020779
Org Biomol Chem. 2022 Jan 12; doi: 10.1039/d1ob02410h. Epub 2022 Jan 12.

A few suitably long dialdehyde and primary diamine building blocks of a predetermined chirality have been designed and synthesized to enable controlled and efficient synthesis of all six possible diastereomers of 4 + 4 macrocyclic amine derived from

Bystander effects induced by direct and scattered radiation generated during penetration of medium inside a water phantom.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

Konopacka M, Rogoliński J, Slosarek K.
PMID: 24376990
Rep Pract Oncol Radiother. 2011 Oct 29;16(6):256-61. doi: 10.1016/j.rpor.2011.10.001. eCollection 2011.

BACKGROUND: The biological effects of ionizing radiation have long been thought to results from direct targeting of the nucleus leading to DNA damage. Over the years, a number of non-targeted or epigenetic effects of radiation exposure have been reported...

From 2 + 2 to 8 + 8 Condensation Products of Diamine and Dialdehyde: Giant Container-Shaped Macrocycles for Multiple Anion Binding.

The Journal of organic chemistry

Gregoliński J, Ślepokura K, Paćkowski T, Panek J, Stefanowicz P, Lisowski J.
PMID: 27304017
J Org Chem. 2016 Jul 01;81(13):5285-94. doi: 10.1021/acs.joc.6b00531. Epub 2016 Jun 21.

The combination of 2,6-diformylpyridine and trans-1,2-diaminocyclopentane fragments results in 2 + 2, 3 + 3, 4 + 4, 6 + 6, and 8 + 8 macrocyclic imine condensation products. These imines can be reduced to the corresponding 2 +...

Fully Conjugated [4]Chrysaorene. Redox-Coupled Anion Binding in a Tetraradicaloid Macrocycle.

Journal of the American Chemical Society

Gregolińska H, Majewski M, Chmielewski PJ, Gregoliński J, Chien A, Zhou J, Wu YL, Bae YJ, Wasielewski MR, Zimmerman PM, Stępień M.
PMID: 30289699
J Am Chem Soc. 2018 Oct 31;140(43):14474-14480. doi: 10.1021/jacs.8b09385. Epub 2018 Oct 16.

[4]Chrysaorene, a fully conjugated carbocyclic coronoid, is shown to be a low-bandgap π-conjugated system with a distinct open-shell character. The system shows good chemical stability and can be oxidized to well-defined radical cation and dication states. The cavity of...

Hexanuclear and Trinuclear Metal Complexes of a Giant Octadecaaza Macrocycle.

Inorganic chemistry

Gregoliński J, Ślepokura K, Lisowski J.
PMID: 29048154
Inorg Chem. 2017 Nov 06;56(21):12719-12727. doi: 10.1021/acs.inorgchem.7b01173.

A large macrocyclic ligand containing six pyridine fragments and six diaminocyclopentane fragments is able to form hexanuclear Zn(II) and Ni(II) complexes as well as a trinuclear Zn(II) complex. X-ray crystal structures of these complexes indicate quite different ligand conformations....

Showing 1 to 12 of 14 entries