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Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8.

ACS medicinal chemistry letters

Larson P, Kucaba TA, Xiong Z, Olin M, Griffith TS, Ferguson DM.
PMID: 29152046
ACS Med Chem Lett. 2017 Oct 16;8(11):1148-1152. doi: 10.1021/acsmedchemlett.7b00256. eCollection 2017 Nov 09.

A series of N1-modified imidazoquinolines were synthesized and screened for Toll-like receptors (TLR) 7 and 8 activities to identify recognition elements that confer high affinity binding and selectivity. These receptors are key targets in the development of immunomodulatory agents...

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Larson P, Kucaba TA, Xiong Z, et al. Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8. ACS Med Chem Lett. 2017;8(11):1148-1152doi: 10.1021/acsmedchemlett.7b00256.
Larson, P., Kucaba, T. A., Xiong, Z., Olin, M., Griffith, T. S., & Ferguson, D. M. (2017). Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8. ACS medicinal chemistry letters, 8(11), 1148-1152. https://doi.org/10.1021/acsmedchemlett.7b00256
Larson, Peter, et al. "Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8." ACS medicinal chemistry letters vol. 8,11 (2017): 1148-1152. doi: https://doi.org/10.1021/acsmedchemlett.7b00256
Larson P, Kucaba TA, Xiong Z, Olin M, Griffith TS, Ferguson DM. Design and Synthesis of N1-Modified Imidazoquinoline Agonists for Selective Activation of Toll-like Receptors 7 and 8. ACS Med Chem Lett. 2017 Oct 16;8(11):1148-1152. doi: 10.1021/acsmedchemlett.7b00256. eCollection 2017 Nov 09. PMID: 29152046; PMCID: PMC5683703.
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Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method.

IMA journal of applied mathematics

Gao H, Carrick D, Berry C, Griffith BE, Luo X.
PMID: 27041786
IMA J Appl Math. 2014 Oct;79(5):978-1010. doi: 10.1093/imamat/hxu029. Epub 2014 Jul 01.

Detailed models of the biomechanics of the heart are important both for developing improved interventions for patients with heart disease and also for patient risk stratification and treatment planning. For instance, stress distributions in the heart affect cardiac remodelling,...

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Gao H, Carrick D, Berry C, et al. Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method. IMA J Appl Math. 2014;79(5):978-1010doi: 10.1093/imamat/hxu029.
Gao, H., Carrick, D., Berry, C., Griffith, B. E., & Luo, X. (2014). Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method. IMA journal of applied mathematics, 79(5), 978-1010. https://doi.org/10.1093/imamat/hxu029
Gao, Hao, et al. "Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method." IMA journal of applied mathematics vol. 79,5 (2014): 978-1010. doi: https://doi.org/10.1093/imamat/hxu029
Gao H, Carrick D, Berry C, Griffith BE, Luo X. Dynamic finite-strain modelling of the human left ventricle in health and disease using an immersed boundary-finite element method. IMA J Appl Math. 2014 Oct;79(5):978-1010. doi: 10.1093/imamat/hxu029. Epub 2014 Jul 01. PMID: 27041786; PMCID: PMC4816497.
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The Challenges of Data Quality Evaluation in a Joint Data Warehouse.

EGEMS (Washington, DC)

Bae CJ, Griffith S, Fan Y, Dunphy C, Thompson N, Urchek J, Parchman A, Katzan IL.
PMID: 26290882
EGEMS (Wash DC). 2015 May 22;3(1):1125. doi: 10.13063/2327-9214.1125. eCollection 2015.

INTRODUCTION: The use of clinically derived data from electronic health records (EHRs) and other electronic clinical systems can greatly facilitate clinical research as well as operational and quality initiatives. One approach for making these data available is to incorporate...

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Bae CJ, Griffith S, Fan Y, et al. The Challenges of Data Quality Evaluation in a Joint Data Warehouse. EGEMS (Wash DC). 2015;3(1):1125doi: 10.13063/2327-9214.1125.
Bae, C. J., Griffith, S., Fan, Y., Dunphy, C., Thompson, N., Urchek, J., Parchman, A., & Katzan, I. L. (2015). The Challenges of Data Quality Evaluation in a Joint Data Warehouse. EGEMS (Washington, DC), 3(1), 1125. https://doi.org/10.13063/2327-9214.1125
Bae, Charles J, et al. "The Challenges of Data Quality Evaluation in a Joint Data Warehouse." EGEMS (Washington, DC) vol. 3,1 (2015): 1125. doi: https://doi.org/10.13063/2327-9214.1125
Bae CJ, Griffith S, Fan Y, Dunphy C, Thompson N, Urchek J, Parchman A, Katzan IL. The Challenges of Data Quality Evaluation in a Joint Data Warehouse. EGEMS (Wash DC). 2015 May 22;3(1):1125. doi: 10.13063/2327-9214.1125. eCollection 2015. PMID: 26290882; PMCID: PMC4537084.
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Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects.

Optics express

Griffith AG, Yu M, Okawachi Y, Cardenas J, Mohanty A, Gaeta AL, Lipson M.
PMID: 27410323
Opt Express. 2016 Jun 13;24(12):13044-50. doi: 10.1364/OE.24.013044.

We demonstrate the first low-noise mid-IR frequency comb source using a silicon microresonator. Our observation of strong Raman scattering lines in the generated comb suggests that interplay between Raman and four-wave mixing plays a role in the generated low-noise...

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Griffith AG, Yu M, Okawachi Y, et al. Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Opt Express. 2016;24(12):13044-50doi: 10.1364/OE.24.013044.
Griffith, A. G., Yu, M., Okawachi, Y., Cardenas, J., Mohanty, A., Gaeta, A. L., & Lipson, M. (2016). Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Optics express, 24(12), 13044-50. https://doi.org/10.1364/OE.24.013044
Griffith, Austin G, et al. "Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects." Optics express vol. 24,12 (2016): 13044-50. doi: https://doi.org/10.1364/OE.24.013044
Griffith AG, Yu M, Okawachi Y, Cardenas J, Mohanty A, Gaeta AL, Lipson M. Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Opt Express. 2016 Jun 13;24(12):13044-50. doi: 10.1364/OE.24.013044. PMID: 27410323.
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Constraints on coastal dune invasion for a notorious plant invader.

AoB PLANTS

Griffith AB, Ahmed T, Hildner AL, Kuckreja S, Long S.
PMID: 26558705
AoB Plants. 2015 Nov 10;7. doi: 10.1093/aobpla/plv126.

Although most biological invasions are not successful, relatively few studies have examined otherwise notorious invaders in systems where they are not highly problematic. The annual grass Bromus tectorum is a dominant invader in western North America, but is usually...

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Griffith AB, Ahmed T, Hildner AL, et al. Constraints on coastal dune invasion for a notorious plant invader. AoB Plants. 2015;7doi: 10.1093/aobpla/plv126.
Griffith, A. B., Ahmed, T., Hildner, A. L., Kuckreja, S., & Long, S. (2015). Constraints on coastal dune invasion for a notorious plant invader. AoB PLANTS, 7. https://doi.org/10.1093/aobpla/plv126
Griffith, Alden B, et al. "Constraints on coastal dune invasion for a notorious plant invader." AoB PLANTS vol. 7 (2015). doi: https://doi.org/10.1093/aobpla/plv126
Griffith AB, Ahmed T, Hildner AL, Kuckreja S, Long S. Constraints on coastal dune invasion for a notorious plant invader. AoB Plants. 2015 Nov 10;7. doi: 10.1093/aobpla/plv126. PMID: 26558705; PMCID: PMC4676798.
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Strategies for Unambiguous Detection of Allelic Heterozygosity via Direct DNA Sequencing of PCR Products: Application to the HLA DRB1 Locus.

Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology

Wu J, Griffith BB, Bassinger S, Moehlenkamp C, Brodie SG, Wu Y, Gribble GG, Troup GM, Williams TM.
PMID: 10330204
Mol Diagn. 1996 Jun;1(2):89-98. doi: 10.1054/MODI00100089.

Background: Many genetic loci exhibit substantial heterogeneity: the human leukocyte antigen (HLA) DRB loci include 139 alleles and the cystic fibrosis transmembrane regulator gene more than 500 known mutations. Identification of alleles at these loci is cumbersome with typical...

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Wu J, Griffith BB, Bassinger S, et al. Strategies for Unambiguous Detection of Allelic Heterozygosity via Direct DNA Sequencing of PCR Products: Application to the HLA DRB1 Locus. Mol Diagn. 1996;1(2):89-98doi: 10.1054/MODI00100089.
Wu, J., Griffith, B. B., Bassinger, S., Moehlenkamp, C., Brodie, S. G., Wu, Y., Gribble, G. G., Troup, G. M., & Williams, T. M. (1996). Strategies for Unambiguous Detection of Allelic Heterozygosity via Direct DNA Sequencing of PCR Products: Application to the HLA DRB1 Locus. Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology, 1(2), 89-98. https://doi.org/10.1054/MODI00100089
Wu, et al. "Strategies for Unambiguous Detection of Allelic Heterozygosity via Direct DNA Sequencing of PCR Products: Application to the HLA DRB1 Locus." Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology vol. 1,2 (1996): 89-98. doi: https://doi.org/10.1054/MODI00100089
Wu J, Griffith BB, Bassinger S, Moehlenkamp C, Brodie SG, Wu Y, Gribble GG, Troup GM, Williams TM. Strategies for Unambiguous Detection of Allelic Heterozygosity via Direct DNA Sequencing of PCR Products: Application to the HLA DRB1 Locus. Mol Diagn. 1996 Jun;1(2):89-98. doi: 10.1054/MODI00100089. PMID: 10330204.
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Integrating women's health issues into third-year medical and surgical curricula.

Academic medicine : journal of the Association of American Medical Colleges

Kwolek D, Blue A, Griffith C.
PMID: 10676341
Acad Med. 1997 May;72(5):422. doi: 10.1097/00001888-199705000-00047.

No abstract available.

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Kwolek D, Blue A, Griffith C. Integrating women's health issues into third-year medical and surgical curricula. Acad Med. 1997;72(5):422doi: 10.1097/00001888-199705000-00047.
Kwolek, D., Blue, A., & Griffith, C. (1997). Integrating women's health issues into third-year medical and surgical curricula. Academic medicine : journal of the Association of American Medical Colleges, 72(5), 422. https://doi.org/10.1097/00001888-199705000-00047
Kwolek, D, et al. "Integrating women's health issues into third-year medical and surgical curricula." Academic medicine : journal of the Association of American Medical Colleges vol. 72,5 (1997): 422. doi: https://doi.org/10.1097/00001888-199705000-00047
Kwolek D, Blue A, Griffith C. Integrating women's health issues into third-year medical and surgical curricula. Acad Med. 1997 May;72(5):422. doi: 10.1097/00001888-199705000-00047. PMID: 10676341.
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ARE PERMANENT DISTURBANCES OF EQUILIBRATION INHERITED?.

Science (New York, N.Y.)

Griffith CR.
PMID: 17778266
Science. 1922 Dec 15;56(1459):676-8. doi: 10.1126/science.56.1459.676.

No abstract available.

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Griffith CR. ARE PERMANENT DISTURBANCES OF EQUILIBRATION INHERITED?. Science. 1922;56(1459):676-8doi: 10.1126/science.56.1459.676.
Griffith, C. R. (1922). ARE PERMANENT DISTURBANCES OF EQUILIBRATION INHERITED?. Science (New York, N.Y.), 56(1459), 676-8. https://doi.org/10.1126/science.56.1459.676
Griffith, C R. "ARE PERMANENT DISTURBANCES OF EQUILIBRATION INHERITED?." Science (New York, N.Y.) vol. 56,1459 (1922): 676-8. doi: https://doi.org/10.1126/science.56.1459.676
Griffith CR. ARE PERMANENT DISTURBANCES OF EQUILIBRATION INHERITED?. Science. 1922 Dec 15;56(1459):676-8. doi: 10.1126/science.56.1459.676. PMID: 17778266.
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A POSSIBLE CASE OF INSTINCTIVE BEHAVIOR IN THE WHITE RAT.

Science (New York, N.Y.)

Griffith CR.
PMID: 17829919
Science. 1919 Aug 15;50(1285):166-7. doi: 10.1126/science.50.1285.166.

No abstract available.

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Griffith CR. A POSSIBLE CASE OF INSTINCTIVE BEHAVIOR IN THE WHITE RAT. Science. 1919;50(1285):166-7doi: 10.1126/science.50.1285.166.
Griffith, C. R. (1919). A POSSIBLE CASE OF INSTINCTIVE BEHAVIOR IN THE WHITE RAT. Science (New York, N.Y.), 50(1285), 166-7. https://doi.org/10.1126/science.50.1285.166
Griffith, C R. "A POSSIBLE CASE OF INSTINCTIVE BEHAVIOR IN THE WHITE RAT." Science (New York, N.Y.) vol. 50,1285 (1919): 166-7. doi: https://doi.org/10.1126/science.50.1285.166
Griffith CR. A POSSIBLE CASE OF INSTINCTIVE BEHAVIOR IN THE WHITE RAT. Science. 1919 Aug 15;50(1285):166-7. doi: 10.1126/science.50.1285.166. PMID: 17829919.
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Structure and formation of the chorion in the butterfly, Calpodes.

Tissue & cell

Griffith CM, Lai-Fook J.
PMID: 18620174
Tissue Cell. 1986;18(4):589-601. doi: 10.1016/0040-8166(86)90023-6.

The hemispherical eggshell of Calpodes consists of a domed dorsal surface of thin inner endochorion and a thick, lamellate, outer exochorion, and a flat bottom of predominantly unlamellated endochorion. The endochorion is traversed by small pores and the exochorion...

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Griffith CM, Lai-Fook J. Structure and formation of the chorion in the butterfly, Calpodes. Tissue Cell. 1986;18(4):589-601doi: 10.1016/0040-8166(86)90023-6.
Griffith, C. M., & Lai-Fook, J. (1986). Structure and formation of the chorion in the butterfly, Calpodes. Tissue & cell, 18(4), 589-601. https://doi.org/10.1016/0040-8166(86)90023-6
Griffith, C M, and Lai-Fook, J. "Structure and formation of the chorion in the butterfly, Calpodes." Tissue & cell vol. 18,4 (1986): 589-601. doi: https://doi.org/10.1016/0040-8166(86)90023-6
Griffith CM, Lai-Fook J. Structure and formation of the chorion in the butterfly, Calpodes. Tissue Cell. 1986;18(4):589-601. doi: 10.1016/0040-8166(86)90023-6. PMID: 18620174.
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THE GENETICS OF RETINOBLASTOMA.

The British journal of ophthalmology

Griffith AD, Sorsby A.
PMID: 18170018
Br J Ophthalmol. 1944 Jun;28(6):279-93. doi: 10.1136/bjo.28.6.279.

No abstract available.

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Griffith AD, Sorsby A. THE GENETICS OF RETINOBLASTOMA. Br J Ophthalmol. 1944;28(6):279-93doi: 10.1136/bjo.28.6.279.
Griffith, A. D., & Sorsby, A. (1944). THE GENETICS OF RETINOBLASTOMA. The British journal of ophthalmology, 28(6), 279-93. https://doi.org/10.1136/bjo.28.6.279
Griffith, A D, and Sorsby, A. "THE GENETICS OF RETINOBLASTOMA." The British journal of ophthalmology vol. 28,6 (1944): 279-93. doi: https://doi.org/10.1136/bjo.28.6.279
Griffith AD, Sorsby A. THE GENETICS OF RETINOBLASTOMA. Br J Ophthalmol. 1944 Jun;28(6):279-93. doi: 10.1136/bjo.28.6.279. PMID: 18170018; PMCID: PMC510367.
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Discussion on the Indications for, and Technique of, Caesarean Section and its Alternatives, in Women with Contracted Pelves, who have been long in Labour and exposed to Septic Infection.

Proceedings of the Royal Society of Medicine

Griffith WS.
PMID: 19975282
Proc R Soc Med. 1911;4:203-4.

No abstract available.

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Griffith WS. Discussion on the Indications for, and Technique of, Caesarean Section and its Alternatives, in Women with Contracted Pelves, who have been long in Labour and exposed to Septic Infection. Proc R Soc Med. 1911;4:203-4
Griffith, W. S. (1911). Discussion on the Indications for, and Technique of, Caesarean Section and its Alternatives, in Women with Contracted Pelves, who have been long in Labour and exposed to Septic Infection. Proceedings of the Royal Society of Medicine, 4203-4.
Griffith, W S. "Discussion on the Indications for, and Technique of, Caesarean Section and its Alternatives, in Women with Contracted Pelves, who have been long in Labour and exposed to Septic Infection." Proceedings of the Royal Society of Medicine vol. 4 (1911): 203-4.
Griffith WS. Discussion on the Indications for, and Technique of, Caesarean Section and its Alternatives, in Women with Contracted Pelves, who have been long in Labour and exposed to Septic Infection. Proc R Soc Med. 1911;4:203-4. PMID: 19975282; PMCID: PMC2005114.
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Showing 1 to 12 of 325 entries