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The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems.

The Journal of organic chemistry

Smith AC, Cabral S, Kung DW, Rose CR, Southers JA, García-Irizarry CN, Damon DB, Bagley SW, Griffith DA.
PMID: 27056793
J Org Chem. 2016 May 06;81(9):3509-19. doi: 10.1021/acs.joc.5b02890. Epub 2016 Apr 25.

The synthesis of a series of pharmaceutically important N-protected methyl-substituted spirocyclic piperidine-azetidine (2,7-diazaspiro[3.5]nonane) and spirocyclic piperidine-pyrrolidine (2,8-diazaspiro[4.5]decane) ring systems was developed. These motifs contain two differentiated sites (protected secondary amines) to allow for further functionalization via reductive amination, amidation,...

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Smith AC, Cabral S, Kung DW, et al. The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems. J Org Chem. 2016;81(9):3509-19doi: 10.1021/acs.joc.5b02890.
Smith, A. C., Cabral, S., Kung, D. W., Rose, C. R., Southers, J. A., García-Irizarry, C. N., Damon, D. B., Bagley, S. W., & Griffith, D. A. (2016). The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems. The Journal of organic chemistry, 81(9), 3509-19. https://doi.org/10.1021/acs.joc.5b02890
Smith, Aaron C, et al. "The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems." The Journal of organic chemistry vol. 81,9 (2016): 3509-19. doi: https://doi.org/10.1021/acs.joc.5b02890
Smith AC, Cabral S, Kung DW, Rose CR, Southers JA, García-Irizarry CN, Damon DB, Bagley SW, Griffith DA. The Synthesis of Methyl-Substituted Spirocyclic Piperidine-Azetidine (2,7-Diazaspiro[3.5]nonane) and Spirocyclic Piperidine-Pyrrolidine (2,8-Diazaspiro[4.5]decane) Ring Systems. J Org Chem. 2016 May 06;81(9):3509-19. doi: 10.1021/acs.joc.5b02890. Epub 2016 Apr 25. PMID: 27056793.
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The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation.

Frontiers in bioengineering and biotechnology

Griffith M, Islam MM, Edin J, Papapavlou G, Buznyk O, Patra HK.
PMID: 27668213
Front Bioeng Biotechnol. 2016 Sep 09;4:71. doi: 10.3389/fbioe.2016.00071. eCollection 2016.

Biomaterials are now being used or evaluated clinically as implants to supplement the severe shortage of available human donor organs. To date, however, such implants have mainly been developed as scaffolds to promote the regeneration of failing organs due...

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Griffith M, Islam MM, Edin J, et al. The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation. Front Bioeng Biotechnol. 2016;4:71doi: 10.3389/fbioe.2016.00071.
Griffith, M., Islam, M. M., Edin, J., Papapavlou, G., Buznyk, O., & Patra, H. K. (2016). The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation. Frontiers in bioengineering and biotechnology, 471. https://doi.org/10.3389/fbioe.2016.00071
Griffith, May, et al. "The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation." Frontiers in bioengineering and biotechnology vol. 4 (2016): 71. doi: https://doi.org/10.3389/fbioe.2016.00071
Griffith M, Islam MM, Edin J, Papapavlou G, Buznyk O, Patra HK. The Quest for Anti-inflammatory and Anti-infective Biomaterials in Clinical Translation. Front Bioeng Biotechnol. 2016 Sep 09;4:71. doi: 10.3389/fbioe.2016.00071. eCollection 2016. PMID: 27668213; PMCID: PMC5016531.
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Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings.

British journal of clinical pharmacology

Pearson RM, Griffith DN, Woollard M, James IM, Havard CW.
PMID: 26635166
Br J Clin Pharmacol. 1979 Apr;8:195S-8S. doi: 10.1111/j.1365-2125.1979.tb04780.x.

1 Diazoxide 300 mg and labetalol 150 mg were each injected intravenously on separate occasions into five patients with essentail hypertension. The reduction in BP caused by labetalol was slightly greater than that produced by diazoxide. 2 In contrast...

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Pearson RM, Griffith DN, Woollard M, et al. Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings. Br J Clin Pharmacol. 1979;8:195S-8Sdoi: 10.1111/j.1365-2125.1979.tb04780.x.
Pearson, R. M., Griffith, D. N., Woollard, M., James, I. M., & Havard, C. W. (1979). Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings. British journal of clinical pharmacology, 8195S-8S. https://doi.org/10.1111/j.1365-2125.1979.tb04780.x
Pearson, R M, et al. "Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings." British journal of clinical pharmacology vol. 8 (1979): 195S-8S. doi: https://doi.org/10.1111/j.1365-2125.1979.tb04780.x
Pearson RM, Griffith DN, Woollard M, James IM, Havard CW. Comparison of effects on cerebral blood flow of rapid reduction in systemic arterial pressure by diazoxide and labetalol in hypertensive patients: preliminary findings. Br J Clin Pharmacol. 1979 Apr;8:195S-8S. doi: 10.1111/j.1365-2125.1979.tb04780.x. PMID: 26635166.
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Advantage of impulse oscillometry over spirometry to diagnose chronic obstructive pulmonary disease and monitor pulmonary responses to bronchodilators: An observational study.

SAGE open medicine

Saadeh C, Saadeh C, Cross B, Gaylor M, Griffith M.
PMID: 26770777
SAGE Open Med. 2015 Apr 06;3:2050312115578957. doi: 10.1177/2050312115578957. eCollection 2015.

OBJECTIVES: This retrospective study was a comparative analysis of sensitivity of impulse oscillometry and spirometry techniques for use in a mixed chronic obstructive pulmonary disease group for assessing disease severity and inhalation therapy.METHODS: A total of 30 patients with...

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Saadeh C, Saadeh C, Cross B, et al. Advantage of impulse oscillometry over spirometry to diagnose chronic obstructive pulmonary disease and monitor pulmonary responses to bronchodilators: An observational study. SAGE Open Med. 2015;3:2050312115578957doi: 10.1177/2050312115578957.
Saadeh, C., Saadeh, C., Cross, B., Gaylor, M., & Griffith, M. (2015). Advantage of impulse oscillometry over spirometry to diagnose chronic obstructive pulmonary disease and monitor pulmonary responses to bronchodilators: An observational study. SAGE open medicine, 32050312115578957. https://doi.org/10.1177/2050312115578957
Saadeh, Constantine, et al. "Advantage of impulse oscillometry over spirometry to diagnose chronic obstructive pulmonary disease and monitor pulmonary responses to bronchodilators: An observational study." SAGE open medicine vol. 3 (2015): 2050312115578957. doi: https://doi.org/10.1177/2050312115578957
Saadeh C, Saadeh C, Cross B, Gaylor M, Griffith M. Advantage of impulse oscillometry over spirometry to diagnose chronic obstructive pulmonary disease and monitor pulmonary responses to bronchodilators: An observational study. SAGE Open Med. 2015 Apr 06;3:2050312115578957. doi: 10.1177/2050312115578957. eCollection 2015. PMID: 26770777; PMCID: PMC4679284.
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Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men.

Health promotion practice

Cornish EK, McKissic SA, Dean DAL, Griffith DM.
PMID: 26637233
Health Promot Pract. 2017 Jan;18(1):102-109. doi: 10.1177/1524839915614800. Epub 2016 Jul 10.

African American men are less likely than White men to meet physical activity recommendations, and few physical activity interventions have focused on the unique needs of African American men. Because health is not more important to men than fulfilling...

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Cornish EK, McKissic SA, Dean DAL, et al. Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men. Health Promot Pract. 2016;18(1):102-109doi: 10.1177/1524839915614800.
Cornish, E. K., McKissic, S. A., Dean, D. A. L., & Griffith, D. M. (2017). Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men. Health promotion practice, 18(1), 102-109. https://doi.org/10.1177/1524839915614800
Cornish, Emily K, et al. "Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men." Health promotion practice vol. 18,1 (2017): 102-109. doi: https://doi.org/10.1177/1524839915614800
Cornish EK, McKissic SA, Dean DAL, Griffith DM. Lessons Learned About Motivation From a Pilot Physical Activity Intervention for African American Men. Health Promot Pract. 2017 Jan;18(1):102-109. doi: 10.1177/1524839915614800. Epub 2016 Jul 10. PMID: 26637233; PMCID: PMC4893343.
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Student use and pedagogical impact of a mobile learning application.

Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

Teri S, Acai A, Griffith D, Mahmoud Q, Ma DW, Newton G.
PMID: 24375862
Biochem Mol Biol Educ. 2014 Mar-Apr;42(2):121-35. doi: 10.1002/bmb.20771. Epub 2013 Dec 20.

Mobile learning (m-learning) is a relevant innovation in teaching and learning in higher education. A mobile app called NutriBiochem was developed for use in biochemistry and nutrition education for students in a second year Biochemistry and Metabolism course. NutriBiochem...

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Teri S, Acai A, Griffith D, et al. Student use and pedagogical impact of a mobile learning application. Biochem Mol Biol Educ. 2013;42(2):121-35doi: 10.1002/bmb.20771.
Teri, S., Acai, A., Griffith, D., Mahmoud, Q., Ma, D. W., & Newton, G. (2014). Student use and pedagogical impact of a mobile learning application. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology, 42(2), 121-35. https://doi.org/10.1002/bmb.20771
Teri, Saskia, et al. "Student use and pedagogical impact of a mobile learning application." Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology vol. 42,2 (2014): 121-35. doi: https://doi.org/10.1002/bmb.20771
Teri S, Acai A, Griffith D, Mahmoud Q, Ma DW, Newton G. Student use and pedagogical impact of a mobile learning application. Biochem Mol Biol Educ. 2014 Mar-Apr;42(2):121-35. doi: 10.1002/bmb.20771. Epub 2013 Dec 20. PMID: 24375862.
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"I AM a Man": Manhood, Minority Men's Health and Health Equity.

Ethnicity & disease

Griffith DM.
PMID: 26672674
Ethn Dis. 2015 Aug 07;25(3):287-93. doi: 10.18865/ed.25.3.287.

OBJECTIVE: To consider how manhood is a key social determinant of minority men's health.DESIGN: This commentary explicates how manhood intersects with other determinants of health to shape minority men's stress responses, health behaviors and health outcomes across the life...

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Griffith DM. "I AM a Man": Manhood, Minority Men's Health and Health Equity. Ethn Dis. 2015;25(3):287-93doi: 10.18865/ed.25.3.287.
Griffith, D. M. (2015). "I AM a Man": Manhood, Minority Men's Health and Health Equity. Ethnicity & disease, 25(3), 287-93. https://doi.org/10.18865/ed.25.3.287
Griffith, Derek M. ""I AM a Man": Manhood, Minority Men's Health and Health Equity." Ethnicity & disease vol. 25,3 (2015): 287-93. doi: https://doi.org/10.18865/ed.25.3.287
Griffith DM. "I AM a Man": Manhood, Minority Men's Health and Health Equity. Ethn Dis. 2015 Aug 07;25(3):287-93. doi: 10.18865/ed.25.3.287. PMID: 26672674; PMCID: PMC4671414.
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High-risk corneal allografts: A therapeutic challenge.

World journal of transplantation

Yu T, Rajendran V, Griffith M, Forrester JV, Kuffová L.
PMID: 27011902
World J Transplant. 2016 Mar 24;6(1):10-27. doi: 10.5500/wjt.v6.i1.10.

Corneal transplantation is the most common surgical procedure amongst solid organ transplants with a high survival rate of 86% at 1-year post-grafting. This high success rate has been attributed to the immune privilege of the eye. However, mechanisms originally...

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Yu T, Rajendran V, Griffith M, et al. High-risk corneal allografts: A therapeutic challenge. World J Transplant. 2016;6(1):10-27doi: 10.5500/wjt.v6.i1.10.
Yu, T., Rajendran, V., Griffith, M., Forrester, J. V., & Kuffová, L. (2016). High-risk corneal allografts: A therapeutic challenge. World journal of transplantation, 6(1), 10-27. https://doi.org/10.5500/wjt.v6.i1.10
Yu, Tian, et al. "High-risk corneal allografts: A therapeutic challenge." World journal of transplantation vol. 6,1 (2016): 10-27. doi: https://doi.org/10.5500/wjt.v6.i1.10
Yu T, Rajendran V, Griffith M, Forrester JV, Kuffová L. High-risk corneal allografts: A therapeutic challenge. World J Transplant. 2016 Mar 24;6(1):10-27. doi: 10.5500/wjt.v6.i1.10. PMID: 27011902; PMCID: PMC4801785.
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Ablation of Arrhythmias in Patients with Adult Congenital Heart Disease.

Arrhythmia & electrophysiology review

Lobo RG, Griffith M, De Bono J.
PMID: 26835063
Arrhythm Electrophysiol Rev. 2014 May;3(1):36-9. doi: 10.15420/aer.2011.3.1.36. Epub 2014 May 18.

Arrhythmias in adults with congenital heart disease, most commonly related to previous surgical procedures, are a frequent comorbidity in this growing population thanks to the improved outcome of surgical techniques. Re-entrant circuits around areas of scarring and natural barriers,...

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Lobo RG, Griffith M, De Bono J. Ablation of Arrhythmias in Patients with Adult Congenital Heart Disease. Arrhythm Electrophysiol Rev. 2014;3(1):36-9doi: 10.15420/aer.2011.3.1.36.
Lobo, R. G., Griffith, M., & De Bono, J. (2014). Ablation of Arrhythmias in Patients with Adult Congenital Heart Disease. Arrhythmia & electrophysiology review, 3(1), 36-9. https://doi.org/10.15420/aer.2011.3.1.36
Lobo, Rodrigo Gallardo, et al. "Ablation of Arrhythmias in Patients with Adult Congenital Heart Disease." Arrhythmia & electrophysiology review vol. 3,1 (2014): 36-9. doi: https://doi.org/10.15420/aer.2011.3.1.36
Lobo RG, Griffith M, De Bono J. Ablation of Arrhythmias in Patients with Adult Congenital Heart Disease. Arrhythm Electrophysiol Rev. 2014 May;3(1):36-9. doi: 10.15420/aer.2011.3.1.36. Epub 2014 May 18. PMID: 26835063; PMCID: PMC4711531.
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Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects.

Optics express

Griffith AG, Yu M, Okawachi Y, Cardenas J, Mohanty A, Gaeta AL, Lipson M.
PMID: 27410323
Opt Express. 2016 Jun 13;24(12):13044-50. doi: 10.1364/OE.24.013044.

We demonstrate the first low-noise mid-IR frequency comb source using a silicon microresonator. Our observation of strong Raman scattering lines in the generated comb suggests that interplay between Raman and four-wave mixing plays a role in the generated low-noise...

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Griffith AG, Yu M, Okawachi Y, et al. Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Opt Express. 2016;24(12):13044-50doi: 10.1364/OE.24.013044.
Griffith, A. G., Yu, M., Okawachi, Y., Cardenas, J., Mohanty, A., Gaeta, A. L., & Lipson, M. (2016). Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Optics express, 24(12), 13044-50. https://doi.org/10.1364/OE.24.013044
Griffith, Austin G, et al. "Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects." Optics express vol. 24,12 (2016): 13044-50. doi: https://doi.org/10.1364/OE.24.013044
Griffith AG, Yu M, Okawachi Y, Cardenas J, Mohanty A, Gaeta AL, Lipson M. Coherent mid-infrared frequency combs in silicon-microresonators in the presence of Raman effects. Opt Express. 2016 Jun 13;24(12):13044-50. doi: 10.1364/OE.24.013044. PMID: 27410323.
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Constraints on coastal dune invasion for a notorious plant invader.

AoB PLANTS

Griffith AB, Ahmed T, Hildner AL, Kuckreja S, Long S.
PMID: 26558705
AoB Plants. 2015 Nov 10;7. doi: 10.1093/aobpla/plv126.

Although most biological invasions are not successful, relatively few studies have examined otherwise notorious invaders in systems where they are not highly problematic. The annual grass Bromus tectorum is a dominant invader in western North America, but is usually...

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Griffith AB, Ahmed T, Hildner AL, et al. Constraints on coastal dune invasion for a notorious plant invader. AoB Plants. 2015;7doi: 10.1093/aobpla/plv126.
Griffith, A. B., Ahmed, T., Hildner, A. L., Kuckreja, S., & Long, S. (2015). Constraints on coastal dune invasion for a notorious plant invader. AoB PLANTS, 7. https://doi.org/10.1093/aobpla/plv126
Griffith, Alden B, et al. "Constraints on coastal dune invasion for a notorious plant invader." AoB PLANTS vol. 7 (2015). doi: https://doi.org/10.1093/aobpla/plv126
Griffith AB, Ahmed T, Hildner AL, Kuckreja S, Long S. Constraints on coastal dune invasion for a notorious plant invader. AoB Plants. 2015 Nov 10;7. doi: 10.1093/aobpla/plv126. PMID: 26558705; PMCID: PMC4676798.
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Men and Their Father Figures: Exploring Racial and Ethnic Differences in Mental Health Outcomes.

Race and social problems

Watkins DC, Johnson-Lawrence V, Griffith DM.
PMID: 25057330
Race Soc Probl. 2011 Oct;3(3):197-211. doi: 10.1007/s12552-011-9051-5.

Though gender, racial, and ethnic disparities in health in the United States are well documented, it is less clear how these factors intersect to produce patterns of mental health outcomes among men. This study examined the presence of father...

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Watkins DC, Johnson-Lawrence V, Griffith DM. Men and Their Father Figures: Exploring Racial and Ethnic Differences in Mental Health Outcomes. Race Soc Probl. 2011;3(3):197-211doi: 10.1007/s12552-011-9051-5.
Watkins, D. C., Johnson-Lawrence, V., & Griffith, D. M. (2011). Men and Their Father Figures: Exploring Racial and Ethnic Differences in Mental Health Outcomes. Race and social problems, 3(3), 197-211. https://doi.org/10.1007/s12552-011-9051-5
Watkins, Daphne C, et al. "Men and Their Father Figures: Exploring Racial and Ethnic Differences in Mental Health Outcomes." Race and social problems vol. 3,3 (2011): 197-211. doi: https://doi.org/10.1007/s12552-011-9051-5
Watkins DC, Johnson-Lawrence V, Griffith DM. Men and Their Father Figures: Exploring Racial and Ethnic Differences in Mental Health Outcomes. Race Soc Probl. 2011 Oct;3(3):197-211. doi: 10.1007/s12552-011-9051-5. PMID: 25057330; PMCID: PMC4104793.
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Showing 1 to 12 of 373 entries