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Showing 1 to 12 of 775 entries
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Dihydroartemisinin increases temozolomide efficacy in glioma cells by inducing autophagy.

Oncology letters

Zhang ZS, Wang J, Shen YB, Guo CC, Sai KE, Chen FR, Mei X, Han FU, Chen ZP.
PMID: 26171034
Oncol Lett. 2015 Jul;10(1):379-383. doi: 10.3892/ol.2015.3183. Epub 2015 May 06.

Artemisinin, a powerful antimalarial medicine, is extracted from the Chinese herb,

Difluoromethylcarbene for iron-catalyzed cyclopropanation.

Chemical communications (Cambridge, England)

Duan Y, Lin JH, Xiao JC, Gu YC.
PMID: 28317978
Chem Commun (Camb). 2017 Mar 30;53(27):3870-3873. doi: 10.1039/c7cc01636k.

Difluoroethylsulfonium salt, Ph

Transition-Metal-Free TBAI-Facilitated Addition-Cyclization of N-Methyl-N-arylacrylamides with Arylaldehydes or Benzenesulfonohydrazides: Access to Carbonyl- and Sulfone-Containing N-Methyloxindoles.

The Journal of organic chemistry

Ji PY, Zhang MZ, Xu JW, Liu YF, Guo CC.
PMID: 27232267
J Org Chem. 2016 Jun 17;81(12):5181-9. doi: 10.1021/acs.joc.6b00773. Epub 2016 Jun 03.

A highly efficient addition-cyclization of N-methyl-N-arylacrylamides with arylaldehydes or benzenesulfonohydrazides was developed using a catalytic amount of the quaternary ammonium salt (TBAI) under metal-free conditions, leading to the carbonyl- and sulfone-containing oxindoles. Compared to previous methods, which require excessive...

YC-1 induces G.

BioMedicine

Lee MR, Lin C, Lu CC, Kuo SC, Tsao JW, Juan YN, Chiu HY, Lee FY, Yang JS, Tsai FJ.
PMID: 28612710
Biomedicine (Taipei). 2017 Jun;7(2):12. doi: 10.1051/bmdcn/2017070205. Epub 2017 Jun 14.

Oral cancer is a serious and fatal disease. Cisplatin is the first line of chemotherapeutic agent for oral cancer therapy. However, the development of drug resistance and severe side effects cause tremendous problems clinically. In this study, we investigated...

Revitalized and synovialized allograft for intrasynovial flexor tendon reconstruction in an in vivo canine model.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Zhang T, Lu CC, Reisdorf RL, Thoreson AR, Gingery A, Moran SL, Amadio PC, Zhao C.
PMID: 29575268
J Orthop Res. 2018 Mar 25; doi: 10.1002/jor.23889. Epub 2018 Mar 25.

This study was to test our hypothesis that flexor tendon reconstruction with an allograft revitalized with bone marrow stromal cells (BMSCs) and synovialized with carbodiimide derivatized autologous synovial fluid (cd-SYN) would result in better digit functional restoration than the...

Autophagy and its link to type II diabetes mellitus.

BioMedicine

Yang JS, Lu CC, Kuo SC, Hsu YM, Tsai SC, Chen SY, Chen YT, Lin YJ, Huang YC, Chen CJ, Lin WD, Liao WL, Lin WY, Liu YH, Sheu JC, Tsai FJ.
PMID: 28612706
Biomedicine (Taipei). 2017 Jun;7(2):8. doi: 10.1051/bmdcn/2017070201. Epub 2017 Jun 14.

Autophagy, a double-edged sword for cell survival, is the research object on 2016 Nobel Prize in Physiology or Medicine. Autophagy is a molecular mechanism for maintaining cellular physiology and promoting survival. Defects in autophagy lead to the etiology of...

Effects of epidural anesthesia and postoperative epidural analgesia on immune function in esophageal carcinoma patients undergoing thoracic surgery.

Molecular and clinical oncology

Gu CY, Zhang J, Qian YN, Tang QF.
PMID: 25469293
Mol Clin Oncol. 2015 Jan;3(1):190-196. doi: 10.3892/mco.2014.405. Epub 2014 Sep 01.

Thoracic epidural anesthesia (TEA) has been demonstrated to significantly reduce stress and immune dysfunction in trauma patients. In esophageal carcinoma patients undergoing thoracic surgery, TEA combined with general anesthesia during surgery and subsequent postoperative patient-controlled epidural analgesia (PCEA) may...

A three-dimensional cadmium(II) coordination polymer: poly[[[μ-4,4'-(propane-1,3-diyl)dipyridine-κ(2)N:N](μ-3,3'-thiodipropionato-κ(3)O,O':O)cadmium(II)] monohydrate].

Acta crystallographica. Section C, Structural chemistry

Hao XM, Chen G, Gu CS, Liu JW.
PMID: 24992117
Acta Crystallogr C Struct Chem. 2014 Jul;70:712-4. doi: 10.1107/S2053229614013011. Epub 2014 Jun 20.

In the title coordination polymer, {[Cd(C6H8O4S)(C13H14N2)]·H2O}n, the Cd(II) atom displays a distorted octahedral coordination, formed by three carboxylate O atoms and one S atom from three different 3,3'-thiodipropionate ligands, and two N atoms from two different 4,4'-(propane-1,3-diyl)dipyridine ligands. The...

High DEPTOR expression correlates with poor prognosis in patients with esophageal squamous cell carcinoma.

OncoTargets and therapy

Liu NB, Zhang JH, Liu YF, Li J, Zhang ZZ, Li JW, Liu WY, Huang C, Shen T, Gu CW, Gao DY, Wu X, Wu X.
PMID: 26640385
Onco Targets Ther. 2015 Nov 19;8:3449-55. doi: 10.2147/OTT.S92862. eCollection 2015.

OBJECTIVE: The disheveled, Egl-10, and pleckstrin (DEP) domain containing mammalian target of rapamycin (mTOR)-interacting protein (DEPTOR) is a binding protein containing mTOR complex 1 (mTORC1), mTOR complex 2 (mTORC2), and an endogenous mTOR inhibitor. DEPTOR shows abnormal expressions in...

Type I interferon inhibits varicella-zoster virus replication by interfering with the dynamic interaction between mediator and IE62 within replication compartments.

Cell & bioscience

Ku CC, Chang YH, Chien Y, Lee TL.
PMID: 26985360
Cell Biosci. 2016 Mar 16;6:21. doi: 10.1186/s13578-016-0086-6. eCollection 2016.

BACKGROUND: Varicella-zoster virus (VZV) is the causative agent of varicella and zoster. The immediate-early protein, IE62 is the predominant VZ virion tegument protein, transactivating the expression of all kinetic classes of VZV genes. IE62 is localized to punctae that...

Transmission of .

Frontiers in microbiology

Chang KC, Chang LT, Huang YW, Lai YC, Lee CW, Liao JT, Lin NS, Hsu YH, Hu CC.
PMID: 28559888
Front Microbiol. 2017 May 16;8:870. doi: 10.3389/fmicb.2017.00870. eCollection 2017.

No abstract available.

Gold nanoparticles as sensitive optical probes.

The Analyst

Yuan Z, Hu CC, Chang HT, Lu C.
PMID: 26853370
Analyst. 2016 Mar 07;141(5):1611-26. doi: 10.1039/c5an02651b.

Gold nanoparticles (Au NPs) have become one of the most popular materials for sensing of analytes of interest in the last decade, mainly because of their ease in preparation and conjugation, stability, biocompatibility, and size-dependent optical properties. We have...

Showing 1 to 12 of 775 entries