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Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?.

Molecular neurodegeneration

Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V.
PMID: 20843353
Mol Neurodegener. 2010 Sep 15;5:36. doi: 10.1186/1750-1326-5-36.

BACKGROUND: Cholesterol content of cerebral membranes is tightly regulated by elaborate mechanisms that balance the level of cholesterol synthesis, uptake and efflux. Among the conventional regulatory elements, a recent research focus has been nuclear receptors, a superfamily of ligand-activated...

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Akram A, Schmeidler J, Katsel P, et al. Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?. Mol Neurodegener. 2010;5:36doi: 10.1186/1750-1326-5-36.
Akram, A., Schmeidler, J., Katsel, P., Hof, P. R., & Haroutunian, V. (2010). Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?. Molecular neurodegeneration, 536. https://doi.org/10.1186/1750-1326-5-36
Akram, Afia, et al. "Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?." Molecular neurodegeneration vol. 5 (2010): 36. doi: https://doi.org/10.1186/1750-1326-5-36
Akram A, Schmeidler J, Katsel P, Hof PR, Haroutunian V. Increased expression of RXRα in dementia: an early harbinger for the cholesterol dyshomeostasis?. Mol Neurodegener. 2010 Sep 15;5:36. doi: 10.1186/1750-1326-5-36. PMID: 20843353; PMCID: PMC2949865.
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Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases.

International journal of Alzheimer's disease

Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, Pasinetti GM.
PMID: 22666619
Int J Alzheimers Dis. 2012;2012:321280. doi: 10.1155/2012/321280. Epub 2012 May 16.

We investigated the contents of the insulin receptor-beta subunit (IRβ) and [Tyr1162/1163]-phosphorylated IRβ as surrogate indices of total IR content and IR activation in postmortem hippocampal formation brain specimens from nondiabetic sporadic Alzheimer's disease (AD) cases. We found no...

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Ho L, Yemul S, Knable L, et al. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis. 2012;2012:321280doi: 10.1155/2012/321280.
Ho, L., Yemul, S., Knable, L., Katsel, P., Zhao, R., Haroutunian, V., & Pasinetti, G. M. (2012). Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. International journal of Alzheimer's disease, 2012321280. https://doi.org/10.1155/2012/321280
Ho, Lap, et al. "Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases." International journal of Alzheimer's disease vol. 2012 (2012): 321280. doi: https://doi.org/10.1155/2012/321280
Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, Pasinetti GM. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. Int J Alzheimers Dis. 2012;2012:321280. doi: 10.1155/2012/321280. Epub 2012 May 16. PMID: 22666619; PMCID: PMC3362009.
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A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples.

Archives of general psychiatry

Roussos P, Katsel P, Davis KL, Siever LJ, Haroutunian V.
PMID: 22868662
Arch Gen Psychiatry. 2012 Dec;69(12):1205-13. doi: 10.1001/archgenpsychiatry.2012.704.

CONTEXT Schizophrenia is a common, highly heritable, neurodevelopmental mental illness, characterized by genetic heterogeneity. OBJECTIVE To identify abnormalities in the transcriptome organization among older persons with schizophrenia and controls. DESIGN Weighted gene coexpression network analysis based on microarray transcriptomic...

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Roussos P, Katsel P, Davis KL, et al. A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Arch Gen Psychiatry. 2012;69(12):1205-13doi: 10.1001/archgenpsychiatry.2012.704.
Roussos, P., Katsel, P., Davis, K. L., Siever, L. J., & Haroutunian, V. (2012). A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Archives of general psychiatry, 69(12), 1205-13. https://doi.org/10.1001/archgenpsychiatry.2012.704
Roussos, Panos, et al. "A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples." Archives of general psychiatry vol. 69,12 (2012): 1205-13. doi: https://doi.org/10.1001/archgenpsychiatry.2012.704
Roussos P, Katsel P, Davis KL, Siever LJ, Haroutunian V. A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Arch Gen Psychiatry. 2012 Dec;69(12):1205-13. doi: 10.1001/archgenpsychiatry.2012.704. PMID: 22868662.
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Writhing.

Journal of pain & palliative care pharmacotherapy

Haroutounian S.
PMID: 29381132
J Pain Palliat Care Pharmacother. 2017 Sep - Dec;31(3):189. doi: 10.1080/15360288.2018.1427383.

No abstract available.

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Haroutounian S. Writhing. J Pain Palliat Care Pharmacother. 2017;31(3):189doi: 10.1080/15360288.2018.1427383.
Haroutounian, S. (2017). Writhing. Journal of pain & palliative care pharmacotherapy, 31(3), 189. https://doi.org/10.1080/15360288.2018.1427383
Haroutounian, Simon. "Writhing." Journal of pain & palliative care pharmacotherapy vol. 31,3 (2017): 189. doi: https://doi.org/10.1080/15360288.2018.1427383
Haroutounian S. Writhing. J Pain Palliat Care Pharmacother. 2017 Sep - Dec;31(3):189. doi: 10.1080/15360288.2018.1427383. PMID: 29381132.
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Effect of pomegranate juice consumption on biochemical parameters and complete blood count.

Experimental and therapeutic medicine

Manthou E, Georgakouli K, Deli CK, Sotiropoulos A, Fatouros IG, Kouretas D, Haroutounian S, Matthaiou C, Koutedakis Y, Jamurtas AZ.
PMID: 28781633
Exp Ther Med. 2017 Aug;14(2):1756-1762. doi: 10.3892/etm.2017.4690. Epub 2017 Jun 27.

Pomegranate has been used therapeutically for centuries. The aim of the present study was to examine the effects of pomegranate juice (PJ) supplementation on complete blood count (CBC), glucose, blood lipids and C-reactive protein (CRP) in healthy subjects. A...

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Manthou E, Georgakouli K, Deli CK, et al. Effect of pomegranate juice consumption on biochemical parameters and complete blood count. Exp Ther Med. 2017;14(2):1756-1762doi: 10.3892/etm.2017.4690.
Manthou, E., Georgakouli, K., Deli, C. K., Sotiropoulos, A., Fatouros, I. G., Kouretas, D., Haroutounian, S., Matthaiou, C., Koutedakis, Y., & Jamurtas, A. Z. (2017). Effect of pomegranate juice consumption on biochemical parameters and complete blood count. Experimental and therapeutic medicine, 14(2), 1756-1762. https://doi.org/10.3892/etm.2017.4690
Manthou, Eirini, et al. "Effect of pomegranate juice consumption on biochemical parameters and complete blood count." Experimental and therapeutic medicine vol. 14,2 (2017): 1756-1762. doi: https://doi.org/10.3892/etm.2017.4690
Manthou E, Georgakouli K, Deli CK, Sotiropoulos A, Fatouros IG, Kouretas D, Haroutounian S, Matthaiou C, Koutedakis Y, Jamurtas AZ. Effect of pomegranate juice consumption on biochemical parameters and complete blood count. Exp Ther Med. 2017 Aug;14(2):1756-1762. doi: 10.3892/etm.2017.4690. Epub 2017 Jun 27. PMID: 28781633; PMCID: PMC5526177.
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MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis.

Molecular psychiatry

Cao J, Huang M, Guo L, Zhu L, Hou J, Zhang L, Pero A, Ng S, El Gaamouch F, Elder G, Sano M, Goate A, Tcw J, Haroutunian V, Zhang B, Cai D.
PMID: 32632205
Mol Psychiatry. 2021 Sep;26(9):4687-4701. doi: 10.1038/s41380-020-0824-3. Epub 2020 Jul 06.

Our recent findings link the apolipoprotein E4 (ApoE4)-specific changes in brain phosphoinositol biphosphate (PIP

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Cao J, Huang M, Guo L, et al. MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. Mol Psychiatry. 2020;26(9):4687-4701doi: 10.1038/s41380-020-0824-3.
Cao, J., Huang, M., Guo, L., Zhu, L., Hou, J., Zhang, L., Pero, A., Ng, S., El Gaamouch, F., Elder, G., Sano, M., Goate, A., Tcw, J., Haroutunian, V., Zhang, B., & Cai, D. (2021). MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. Molecular psychiatry, 26(9), 4687-4701. https://doi.org/10.1038/s41380-020-0824-3
Cao, Jiqing, et al. "MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis." Molecular psychiatry vol. 26,9 (2021): 4687-4701. doi: https://doi.org/10.1038/s41380-020-0824-3
Cao J, Huang M, Guo L, Zhu L, Hou J, Zhang L, Pero A, Ng S, El Gaamouch F, Elder G, Sano M, Goate A, Tcw J, Haroutunian V, Zhang B, Cai D. MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer's disease pathogenesis. Mol Psychiatry. 2021 Sep;26(9):4687-4701. doi: 10.1038/s41380-020-0824-3. Epub 2020 Jul 06. PMID: 32632205; PMCID: PMC7785685.
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Two-photon microscopy imaging of oxidative stress in human living erythrocytes.

Biomedical optics express

Tsakanova G, Arakelova E, Ayvazyan V, Ayvazyan A, Tatikyan S, Aroutiounian R, Dalyan Y, Haroutiunian S, Tsakanov V, Arakelyan A.
PMID: 29296508
Biomed Opt Express. 2017 Nov 30;8(12):5834-5846. doi: 10.1364/BOE.8.005834. eCollection 2017 Dec 01.

Red blood cells (RBCs) are known to be the most suitable cells to study oxidative stress, which is implicated in the etiopathology of many human diseases. The goal of the current study was to develop a new effective approach...

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Tsakanova G, Arakelova E, Ayvazyan V, et al. Two-photon microscopy imaging of oxidative stress in human living erythrocytes. Biomed Opt Express. 2017;8(12):5834-5846doi: 10.1364/BOE.8.005834.
Tsakanova, G., Arakelova, E., Ayvazyan, V., Ayvazyan, A., Tatikyan, S., Aroutiounian, R., Dalyan, Y., Haroutiunian, S., Tsakanov, V., & Arakelyan, A. (2017). Two-photon microscopy imaging of oxidative stress in human living erythrocytes. Biomedical optics express, 8(12), 5834-5846. https://doi.org/10.1364/BOE.8.005834
Tsakanova, Gohar, et al. "Two-photon microscopy imaging of oxidative stress in human living erythrocytes." Biomedical optics express vol. 8,12 (2017): 5834-5846. doi: https://doi.org/10.1364/BOE.8.005834
Tsakanova G, Arakelova E, Ayvazyan V, Ayvazyan A, Tatikyan S, Aroutiounian R, Dalyan Y, Haroutiunian S, Tsakanov V, Arakelyan A. Two-photon microscopy imaging of oxidative stress in human living erythrocytes. Biomed Opt Express. 2017 Nov 30;8(12):5834-5846. doi: 10.1364/BOE.8.005834. eCollection 2017 Dec 01. PMID: 29296508; PMCID: PMC5745123.
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The sodium-channel blocker lidocaine in subanesthetic concentrations reduces spontaneous and evoked pain in human painful neuroma.

Scandinavian journal of pain

Finnerup NB, Haroutounian S, Nikolajsen L.
PMID: 29911611
Scand J Pain. 2015 Jul 01;8(1):45-46. doi: 10.1016/j.sjpain.2015.05.003.

No abstract available.

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Finnerup NB, Haroutounian S, Nikolajsen L. The sodium-channel blocker lidocaine in subanesthetic concentrations reduces spontaneous and evoked pain in human painful neuroma. Scand J Pain. 2015;8(1):45-46doi: 10.1016/j.sjpain.2015.05.003.
Finnerup, N. B., Haroutounian, S., & Nikolajsen, L. (2015). The sodium-channel blocker lidocaine in subanesthetic concentrations reduces spontaneous and evoked pain in human painful neuroma. Scandinavian journal of pain, 8(1), 45-46. https://doi.org/10.1016/j.sjpain.2015.05.003
Finnerup, Nanna Brix, et al. "The sodium-channel blocker lidocaine in subanesthetic concentrations reduces spontaneous and evoked pain in human painful neuroma." Scandinavian journal of pain vol. 8,1 (2015): 45-46. doi: https://doi.org/10.1016/j.sjpain.2015.05.003
Finnerup NB, Haroutounian S, Nikolajsen L. The sodium-channel blocker lidocaine in subanesthetic concentrations reduces spontaneous and evoked pain in human painful neuroma. Scand J Pain. 2015 Jul 01;8(1):45-46. doi: 10.1016/j.sjpain.2015.05.003. PMID: 29911611.
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Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation.

The journal of pain

Nemenov MI, Alaverdyan H, Burk C, Roles K, Frey K, Yan Y, Kazinets G, Haroutounian S.
PMID: 34896646
J Pain. 2021 Dec 09; doi: 10.1016/j.jpain.2021.11.011. Epub 2021 Dec 09.

Painful chemotherapy induced peripheral neuropathy (CIPN) is a common complication of chemotherapy with drugs such as taxanes and platinum compounds. Currently, no methods are available for early detection of sensory changes that are associated with painful CIPN, nor are...

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Nemenov MI, Alaverdyan H, Burk C, et al. Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation. J Pain. 2021;doi: 10.1016/j.jpain.2021.11.011.
Nemenov, M. I., Alaverdyan, H., Burk, C., Roles, K., Frey, K., Yan, Y., Kazinets, G., & Haroutounian, S. (2021). Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation. The journal of pain, . https://doi.org/10.1016/j.jpain.2021.11.011
Nemenov, Mikhail I, et al. "Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation." The journal of pain vol. (2021). doi: https://doi.org/10.1016/j.jpain.2021.11.011
Nemenov MI, Alaverdyan H, Burk C, Roles K, Frey K, Yan Y, Kazinets G, Haroutounian S. Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation. J Pain. 2021 Dec 09; doi: 10.1016/j.jpain.2021.11.011. Epub 2021 Dec 09. PMID: 34896646.
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Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Cross-over Trial.

The Clinical journal of pain

Todorovic MS, Frey K, Swarm RA, Bottros M, Rao L, Tallchief D, Kraus K, Meacham K, Bakos K, Zang X, Lee JB, Kagan L, Haroutounian S.
PMID: 34723864
Clin J Pain. 2021 Nov 01; doi: 10.1097/AJP.0000000000001001. Epub 2021 Nov 01.

OBJECTIVES: Intravenous lidocaine can alleviate painful diabetic peripheral neuropathy (DPN) in some patients. Whether quantitative sensory testing (QST) can identify treatment responders have not been prospectively tested.METHODS: This was a prospective, randomized, double-blind, crossover, placebo-controlled trial comparing intravenous lidocaine...

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Todorovic MS, Frey K, Swarm RA, et al. Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Cross-over Trial. Clin J Pain. 2021;doi: 10.1097/AJP.0000000000001001.
Todorovic, M. S., Frey, K., Swarm, R. A., Bottros, M., Rao, L., Tallchief, D., Kraus, K., Meacham, K., Bakos, K., Zang, X., Lee, J. B., Kagan, L., & Haroutounian, S. (2021). Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Cross-over Trial. The Clinical journal of pain, . https://doi.org/10.1097/AJP.0000000000001001
Todorovic, Marko Slobodan, et al. "Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Cross-over Trial." The Clinical journal of pain vol. (2021). doi: https://doi.org/10.1097/AJP.0000000000001001
Todorovic MS, Frey K, Swarm RA, Bottros M, Rao L, Tallchief D, Kraus K, Meacham K, Bakos K, Zang X, Lee JB, Kagan L, Haroutounian S. Prediction of Individual Analgesic Response to Intravenous Lidocaine in Painful Diabetic Peripheral Neuropathy: A Randomized, Placebo-controlled, Cross-over Trial. Clin J Pain. 2021 Nov 01; doi: 10.1097/AJP.0000000000001001. Epub 2021 Nov 01. PMID: 34723864.
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Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity.

Molecular psychiatry

Wu X, Shukla R, Alganem K, Zhang X, Eby HM, Devine EA, Depasquale E, Reigle J, Simmons M, Hahn MK, Au-Yeung C, Asgariroozbehani R, Hahn CG, Haroutunian V, Meller J, Meador-Woodruff J, McCullumsmith RE.
PMID: 34272489
Mol Psychiatry. 2021 Jul 16; doi: 10.1038/s41380-021-01205-y. Epub 2021 Jul 16.

While the pathophysiology of schizophrenia has been extensively investigated using homogenized postmortem brain samples, few studies have examined changes in brain samples with techniques that may attribute perturbations to specific cell types. To fill this gap, we performed microarray...

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Wu X, Shukla R, Alganem K, et al. Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity. Mol Psychiatry. 2021;doi: 10.1038/s41380-021-01205-y.
Wu, X., Shukla, R., Alganem, K., Zhang, X., Eby, H. M., Devine, E. A., Depasquale, E., Reigle, J., Simmons, M., Hahn, M. K., Au-Yeung, C., Asgariroozbehani, R., Hahn, C. G., Haroutunian, V., Meller, J., Meador-Woodruff, J., & McCullumsmith, R. E. (2021). Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity. Molecular psychiatry, . https://doi.org/10.1038/s41380-021-01205-y
Wu, Xiaojun, et al. "Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity." Molecular psychiatry vol. (2021). doi: https://doi.org/10.1038/s41380-021-01205-y
Wu X, Shukla R, Alganem K, Zhang X, Eby HM, Devine EA, Depasquale E, Reigle J, Simmons M, Hahn MK, Au-Yeung C, Asgariroozbehani R, Hahn CG, Haroutunian V, Meller J, Meador-Woodruff J, McCullumsmith RE. Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity. Mol Psychiatry. 2021 Jul 16; doi: 10.1038/s41380-021-01205-y. Epub 2021 Jul 16. PMID: 34272489; PMCID: PMC8761210.
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Genome-wide association study and functional validation implicates JADE1 in tauopathy.

Acta neuropathologica

Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF.
PMID: 34719765
Acta Neuropathol. 2022 Jan;143(1):33-53. doi: 10.1007/s00401-021-02379-z. Epub 2021 Nov 01.

Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognitive impairment, PART develops independently of amyloid-β (Aβ) plaques. The...

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Farrell K, Kim S, Han N, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2021;143(1):33-53doi: 10.1007/s00401-021-02379-z.
Farrell, K., Kim, S., Han, N., Iida, M. A., Gonzalez, E. M., Otero-Garcia, M., Walker, J. M., Richardson, T. E., Renton, A. E., Andrews, S. J., Fulton-Howard, B., Humphrey, J., Vialle, R. A., Bowles, K. R., de Paiva Lopes, K., Whitney, K., Dangoor, D. K., Walsh, H., Marcora, E., Hefti, M. M., Casella, A., Sissoko, C. T., Kapoor, M., Novikova, G., Udine, E., Wong, G., Tang, W., Bhangale, T., Hunkapiller, J., Ayalon, G., Graham, R. R., Cherry, J. D., Cortes, E. P., Borukov, V. Y., McKee, A. C., Stein, T. D., Vonsattel, J. P., Teich, A. F., Gearing, M., Glass, J., Troncoso, J. C., Frosch, M. P., Hyman, B. T., Dickson, D. W., Murray, M. E., Attems, J., Flanagan, M. E., Mao, Q., Mesulam, M. M., Weintraub, S., Woltjer, R. L., Pham, T., Kofler, J., Schneider, J. A., Yu, L., Purohit, D. P., Haroutunian, V., Hof, P. R., Gandy, S., Sano, M., Beach, T. G., Poon, W., Kawas, C. H., Corrada, M. M., Rissman, R. A., Metcalf, J., Shuldberg, S., Salehi, B., Nelson, P. T., Trojanowski, J. Q., Lee, E. B., Wolk, D. A., McMillan, C. T., Keene, C. D., Latimer, C. S., Montine, T. J., Kovacs, G. G., Lutz, M. I., Fischer, P., Perrin, R. J., Cairns, N. J., Franklin, E. E., Cohen, H. T., Raj, T., Cobos, I., Frost, B., Goate, A., White Iii, C. L., & Crary, J. F. (2022). Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta neuropathologica, 143(1), 33-53. https://doi.org/10.1007/s00401-021-02379-z
Farrell, Kurt, et al. "Genome-wide association study and functional validation implicates JADE1 in tauopathy." Acta neuropathologica vol. 143,1 (2022): 33-53. doi: https://doi.org/10.1007/s00401-021-02379-z
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol. 2022 Jan;143(1):33-53. doi: 10.1007/s00401-021-02379-z. Epub 2021 Nov 01. PMID: 34719765.
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