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Showing 1 to 12 of 220 entries
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Randomized controlled trial of the NS5A inhibitor daclatasvir plus pegylated interferon and ribavirin for HCV genotype-4 (COMMAND-4).

Antiviral therapy

Hézode C, Alric L, Brown A, Hassanein T, Rizzetto M, Buti M, Bourlière M, Thabut D, Molina E, Rustgi V, Samuel D, McPhee F, Liu Z, Yin PD, Hughes E, Treitel M.
PMID: 26313445
Antivir Ther. 2015 Aug 27;21(3):195-205. doi: 10.3851/IMP2985. Epub 2015 Aug 27.

BACKGROUND: Treatment options for HCV genotype-4 (GT4) are limited. This Phase III study (COMMAND-4; AI444-042) evaluated the efficacy and safety of daclatasvir (DCV), a pan-genotypic HCV NS5A inhibitor, with pegylated interferon-α2a/ribavirin (PEG-IFN/RBV) in treatment-naive patients with HCV GT4 infection.METHODS:...

General expressions for downlink signal to interference and noise ratio in homogeneous and heterogeneous LTE-Advanced networks.

Journal of advanced research

Ali NA, Mourad HM, ElSayed HM, El-Soudani M, Amer HH, Daoud RM.
PMID: 27699067
J Adv Res. 2016 Nov;7(6):923-929. doi: 10.1016/j.jare.2016.09.003. Epub 2016 Sep 12.

The interference is the most important problem in LTE or LTE-Advanced networks. In this paper, the interference was investigated in terms of the downlink signal to interference and noise ratio (SINR). In order to compare the different frequency reuse...

Atomic and optical properties of warm dense copper.

Physical review. E, Statistical, nonlinear, and soft matter physics

Miloshevsky G, Hassanein A.
PMID: 26465577
Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Sep;92(3):033109. doi: 10.1103/PhysRevE.92.033109. Epub 2015 Sep 29.

The emission of x rays from warm dense matter is of great interest for both spectroscopic diagnostics and development of intense x-ray sources. We report the results from the collisional-radiative steady-state (CRSS) modeling of atomic and optical properties of...

Maternal and Fetal Outcomes in Pregnant Women with a Prosthetic Mechanical Heart Valve.

Clinical Medicine Insights. Cardiology

Ayad SW, Hassanein MM, Mohamed EA, Gohar AM.
PMID: 26884686
Clin Med Insights Cardiol. 2016 Feb 10;10:11-7. doi: 10.4137/CMC.S36740. eCollection 2016.

BACKGROUND: Pregnancy is associated with several cardiocirculatory changes that can significantly impact underlying cardiac disease. These changes include an increase in cardiac output, sodium, and water retention leading to blood volume expansion, and reductions in systemic vascular resistance and...

The Evolution of Prognostic Factors in Multiple Myeloma.

Advances in hematology

Hanbali A, Hassanein M, Rasheed W, Aljurf M, Alsharif F.
PMID: 28321258
Adv Hematol. 2017;2017:4812637. doi: 10.1155/2017/4812637. Epub 2017 Feb 21.

Multiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last...

Portal vein embolization effect on colorectal cancer liver metastasis progression: Lessons learned.

World journal of clinical oncology

Al-Sharif E, Simoneau E, Hassanain M.
PMID: 26468450
World J Clin Oncol. 2015 Oct 10;6(5):142-6. doi: 10.5306/wjco.v6.i5.142.

Colorectal liver metastasis (CRLM) is the major cause of death in patients diagnosed with colorectal cancer. The gold standard treatment of CRLM is surgical resection. Yet, in the past, more than half of these patients were deemed unresectable due...

The role of interventional radiology in the management of hepatocellular carcinoma.

Current oncology (Toronto, Ont.)

Molla N, AlMenieir N, Simoneau E, Aljiffry M, Valenti D, Metrakos P, Boucher LM, Hassanain M.
PMID: 24940108
Curr Oncol. 2014 Jun;21(3):e480-92. doi: 10.3747/co.21.1829.

BACKGROUND: Hepatocellular carcinoma (hcc) is one of the most common causes of cancer-related death worldwide. Overall, liver transplantation and resection are the only available treatments with potential for cure. Various locoregional therapies are widely used to manage patients with...

Simultaneous determination of Cd, Pb, Cu, Sb, Bi, Se, Zn, Mn, Ni, Co and Fe in water samples by differential pulse stripping voltammetry at a hanging mercury drop electrode.

Fresenius' journal of analytical chemistry

Ghoneim MM, Hassanein AM, Hammam E, Beltagi AM.
PMID: 11225865
Fresenius J Anal Chem. 2000 Jun;367(4):378-83. doi: 10.1007/s002160000410.

A highly sensitive and selective voltammetric procedure is described for the simultaneous determination of eleven elements (Cd, Pb, Cu, Sb, Bi, Se, Zn, Mn, Ni, Co and Fe) in water samples. Firstly, differential pulse anodic stripping voltammetry (DPASV) with...

Mitochondrial dysfunction in liver disease and organ transplantation.

Mitochondrion

Hassanein T, Frederick T.
PMID: 16120418
Mitochondrion. 2004 Sep;4(5):609-20. doi: 10.1016/j.mito.2004.07.015.

The mitochondria play a crucial role in maintaining hepatocyte integrity and functions. Mitochondrial defects are either inherited or acquired. Mitochondria dysfunction occurs when the hepatocyte experience excessive physiologic stress. Its clinical presentation depends on the severity of the stress....

Giant breast tumors.

Annals of Saudi medicine

Hawary MB, Cardoso E, Mahmud S, Hassanain J.
PMID: 17337966
Ann Saudi Med. 1999 Mar-Apr;19(2):174-6. doi: 10.5144/0256-4947.1999.174.

No abstract available.

Massive hemobilia.

Canadian journal of surgery. Journal canadien de chirurgie

Demyttenaere SV, Hassanain M, Halwani Y, Valenti D, Barkun JS.
PMID: 19680496
Can J Surg. 2009 Aug;52(4):E109-E110.

No abstract available.

Shape-Dependent Global Deformation Modes of Large Protein Structures.

Journal of molecular structure

Miloshevsky GV, Hassanein A, Jordan PC.
PMID: 20526444
J Mol Struct. 2010 May 19;972(1):41-50. doi: 10.1016/j.molstruc.2010.01.009.

Conformational changes are central to the functioning of pore-forming proteins that open and close their molecular gates in response to external stimuli such as pH, ionic strength, membrane voltage or ligand binding. Normal mode analysis (NMA) is used to...

Showing 1 to 12 of 220 entries