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History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs.

Journal of clinical medicine

Andrès E, Mourot-Cottet R, Maloisel F, Keller O, Vogel T, Séverac F, Tebacher M, Gottenberg JE, Weber JC, Kaltenbach G, Goichot B, Sibilia J, Korganow AS, Herbrecht R.
PMID: 28954408
J Clin Med. 2017 Sep 26;6(10). doi: 10.3390/jcm6100092.

BACKGROUND: Despite major advances in its prevention and treatment, febrile neutropenia remains a most concerning complication of cancer chemotherapy. Outside the oncology setting, however, only few data are currently available on febrile neutropenia related to non-chemotherapy drugs. We report...

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Andrès E, Mourot-Cottet R, Maloisel F, et al. History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs. J Clin Med. 2017;6(10)doi: 10.3390/jcm6100092.
Andrès, E., Mourot-Cottet, R., Maloisel, F., Keller, O., Vogel, T., Séverac, F., Tebacher, M., Gottenberg, J. E., Weber, J. C., Kaltenbach, G., Goichot, B., Sibilia, J., Korganow, A. S., & Herbrecht, R. (2017). History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs. Journal of clinical medicine, 6(10), . https://doi.org/10.3390/jcm6100092
Andrès, Emmanuel, et al. "History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs." Journal of clinical medicine vol. 6,10 (2017). doi: https://doi.org/10.3390/jcm6100092
Andrès E, Mourot-Cottet R, Maloisel F, Keller O, Vogel T, Séverac F, Tebacher M, Gottenberg JE, Weber JC, Kaltenbach G, Goichot B, Sibilia J, Korganow AS, Herbrecht R. History and Outcome of Febrile Neutropenia Outside the Oncology Setting: A Retrospective Study of 76 Cases Related to Non-Chemotherapy Drugs. J Clin Med. 2017 Sep 26;6(10). doi: 10.3390/jcm6100092. PMID: 28954408; PMCID: PMC5664007.
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Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study.

Infectious diseases and therapy

Gangneux JP, El Cheikh J, Herbrecht R, Yakoub-Agha I, Quiniou JB, Caillot D, Michallet M.
PMID: 29948621
Infect Dis Ther. 2018 Sep;7(3):309-325. doi: 10.1007/s40121-018-0203-4. Epub 2018 Jun 09.

INTRODUCTION: The frequency of invasive fungal diseases (IFDs) has increased in recent years. Within a context where both treatments and guidelines are fast evolving, we aim to shed new light on IFD management in hematologic departments in France.METHODS: A...

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Gangneux JP, El Cheikh J, Herbrecht R, et al. Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study. Infect Dis Ther. 2018;7(3):309-325doi: 10.1007/s40121-018-0203-4.
Gangneux, J. P., El Cheikh, J., Herbrecht, R., Yakoub-Agha, I., Quiniou, J. B., Caillot, D., & Michallet, M. (2018). Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study. Infectious diseases and therapy, 7(3), 309-325. https://doi.org/10.1007/s40121-018-0203-4
Gangneux, Jean-Pierre, et al. "Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study." Infectious diseases and therapy vol. 7,3 (2018): 309-325. doi: https://doi.org/10.1007/s40121-018-0203-4
Gangneux JP, El Cheikh J, Herbrecht R, Yakoub-Agha I, Quiniou JB, Caillot D, Michallet M. Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study. Infect Dis Ther. 2018 Sep;7(3):309-325. doi: 10.1007/s40121-018-0203-4. Epub 2018 Jun 09. PMID: 29948621; PMCID: PMC6098753.
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Clinical antifungal efficacy trials in invasive aspergillosis: Consensus standards for trial design and room for improvement.

Medical mycology

Nivoix Y, Fohrer C, Fornecker L, Herbrecht R.
PMID: 30408917
Med Mycol. 2006 Sep 01;44:S289-S294. doi: 10.1080/13693780600931986.

Despite recent improvements in outcome of invasive aspergillosis there are still high failure and fatality rates. The trial comparing voriconazole to amphotericin B deoxycholate has become a reference for clinical trials in invasive aspergillosis due to the large number...

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Nivoix Y, Fohrer C, Fornecker L, et al. Clinical antifungal efficacy trials in invasive aspergillosis: Consensus standards for trial design and room for improvement. Med Mycol. 2006;44:S289-S294doi: 10.1080/13693780600931986.
Nivoix, Y., Fohrer, C., Fornecker, L., & Herbrecht, R. (2006). Clinical antifungal efficacy trials in invasive aspergillosis: Consensus standards for trial design and room for improvement. Medical mycology, 44S289-S294. https://doi.org/10.1080/13693780600931986
Nivoix, Y, et al. "Clinical antifungal efficacy trials in invasive aspergillosis: Consensus standards for trial design and room for improvement." Medical mycology vol. 44 (2006): S289-S294. doi: https://doi.org/10.1080/13693780600931986
Nivoix Y, Fohrer C, Fornecker L, Herbrecht R. Clinical antifungal efficacy trials in invasive aspergillosis: Consensus standards for trial design and room for improvement. Med Mycol. 2006 Sep 01;44:S289-S294. doi: 10.1080/13693780600931986. PMID: 30408917.
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Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center.

Medicines (Basel, Switzerland)

Andrès E, Lorenzo Villalba N, Mourot-Cottet R, Maloisel F, Tebacher M, Gottenberg JE, Goichot B, Herbrecht R, Zulfiqar AA.
PMID: 32204561
Medicines (Basel). 2020 Mar 19;7(3). doi: 10.3390/medicines7030015.

BACKGROUND: The most important series devoted to antithyroid drug-induced severe neutropenia and agranulocytosis are Japanese studies, almost specifically in relation to the intake of methimazole. The clinical data of 30 Caucasian patients followed up for antithyroid drug-induced neutropenia at...

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Andrès E, Lorenzo Villalba N, Mourot-Cottet R, et al. Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center. Medicines (Basel). 2020;7(3)doi: 10.3390/medicines7030015.
Andrès, E., Lorenzo Villalba, N., Mourot-Cottet, R., Maloisel, F., Tebacher, M., Gottenberg, J. E., Goichot, B., Herbrecht, R., & Zulfiqar, A. A. (2020). Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center. Medicines (Basel, Switzerland), 7(3), . https://doi.org/10.3390/medicines7030015
Andrès, Emmanuel, et al. "Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center." Medicines (Basel, Switzerland) vol. 7,3 (2020). doi: https://doi.org/10.3390/medicines7030015
Andrès E, Lorenzo Villalba N, Mourot-Cottet R, Maloisel F, Tebacher M, Gottenberg JE, Goichot B, Herbrecht R, Zulfiqar AA. Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center. Medicines (Basel). 2020 Mar 19;7(3). doi: 10.3390/medicines7030015. PMID: 32204561; PMCID: PMC7151575.
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Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation.

Nano research

Liu J, Hebbrecht T, Brans T, Parthoens E, Lippens S, Li C, De Keersmaecker H, De Vos WH, De Smedt SC, Boukherroub R, Gettemans J, Xiong R, Braeckmans K.
PMID: 33154805
Nano Res. 2020 Feb;13(2):485-495. doi: 10.1007/s12274-020-2633-z. Epub 2020 Jan 18.

Fluorescence microscopy is the method of choice for studying intracellular dynamics. However, its success depends on the availability of specific and stable markers. A prominent example of markers that are rapidly gaining interest are nanobodies (Nbs, ~ 15 kDa),...

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Liu J, Hebbrecht T, Brans T, et al. Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation. Nano Res. 2020;13(2):485-495doi: 10.1007/s12274-020-2633-z.
Liu, J., Hebbrecht, T., Brans, T., Parthoens, E., Lippens, S., Li, C., De Keersmaecker, H., De Vos, W. H., De Smedt, S. C., Boukherroub, R., Gettemans, J., Xiong, R., & Braeckmans, K. (2020). Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation. Nano research, 13(2), 485-495. https://doi.org/10.1007/s12274-020-2633-z
Liu, Jing, et al. "Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation." Nano research vol. 13,2 (2020): 485-495. doi: https://doi.org/10.1007/s12274-020-2633-z
Liu J, Hebbrecht T, Brans T, Parthoens E, Lippens S, Li C, De Keersmaecker H, De Vos WH, De Smedt SC, Boukherroub R, Gettemans J, Xiong R, Braeckmans K. Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation. Nano Res. 2020 Feb;13(2):485-495. doi: 10.1007/s12274-020-2633-z. Epub 2020 Jan 18. PMID: 33154805; PMCID: PMC7116313.
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Internet use for information seeking in clinical practice: a cross-sectional survey among French general practitioners.

International journal of medical informatics

Bernard E, Arnould M, Saint-Lary O, Duhot D, Hebbrecht G.
PMID: 22425281
Int J Med Inform. 2012 Jul;81(7):493-9. doi: 10.1016/j.ijmedinf.2012.02.001. Epub 2012 Mar 16.

BACKGROUND: Medical information needs regarding patient care are particularly large for general practitioners (GPs). The Internet seems to be a relevant but underused tool to seek medical information.OBJECTIVE: We aimed to describe the characteristics of the French GPs using...

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Bernard E, Arnould M, Saint-Lary O, et al. Internet use for information seeking in clinical practice: a cross-sectional survey among French general practitioners. Int J Med Inform. 2012;81(7):493-9doi: 10.1016/j.ijmedinf.2012.02.001.
Bernard, E., Arnould, M., Saint-Lary, O., Duhot, D., & Hebbrecht, G. (2012). Internet use for information seeking in clinical practice: a cross-sectional survey among French general practitioners. International journal of medical informatics, 81(7), 493-9. https://doi.org/10.1016/j.ijmedinf.2012.02.001
Bernard, Erik, et al. "Internet use for information seeking in clinical practice: a cross-sectional survey among French general practitioners." International journal of medical informatics vol. 81,7 (2012): 493-9. doi: https://doi.org/10.1016/j.ijmedinf.2012.02.001
Bernard E, Arnould M, Saint-Lary O, Duhot D, Hebbrecht G. Internet use for information seeking in clinical practice: a cross-sectional survey among French general practitioners. Int J Med Inform. 2012 Jul;81(7):493-9. doi: 10.1016/j.ijmedinf.2012.02.001. Epub 2012 Mar 16. PMID: 22425281.
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Invasive pulmonary aspergillosis.

Seminars in respiratory and critical care medicine

Herbrecht R, Natarajan-Amé S, Letscher-Bru V, Canuet M.
PMID: 16088462
Semin Respir Crit Care Med. 2004 Apr;25(2):191-202. doi: 10.1055/s-2004-824903.

Invasive pulmonary aspergillosis (IPA) is the most common fungal pulmonary infection in severely immunocompromised patients. Aspergillus species are commonly isolated from the soil, plant debris, and the indoor environment, including the hospital. Phagocytosis is the main host defense against...

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Herbrecht R, Natarajan-Amé S, Letscher-Bru V, et al. Invasive pulmonary aspergillosis. Semin Respir Crit Care Med. 2004;25(2):191-202doi: 10.1055/s-2004-824903.
Herbrecht, R., Natarajan-Amé, S., Letscher-Bru, V., & Canuet, M. (2004). Invasive pulmonary aspergillosis. Seminars in respiratory and critical care medicine, 25(2), 191-202. https://doi.org/10.1055/s-2004-824903
Herbrecht, Raoul, et al. "Invasive pulmonary aspergillosis." Seminars in respiratory and critical care medicine vol. 25,2 (2004): 191-202. doi: https://doi.org/10.1055/s-2004-824903
Herbrecht R, Natarajan-Amé S, Letscher-Bru V, Canuet M. Invasive pulmonary aspergillosis. Semin Respir Crit Care Med. 2004 Apr;25(2):191-202. doi: 10.1055/s-2004-824903. PMID: 16088462.
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Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up.

Journal of oncology

Kim SC, Natarajan-Ame S, Lioure B, Chenard MP, Duclos B, Herbrecht R, Bergerat JP.
PMID: 20454648
J Oncol. 2010;2010:812424. doi: 10.1155/2010/812424. Epub 2010 Apr 29.

Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present...

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Kim SC, Natarajan-Ame S, Lioure B, et al. Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up. J Oncol. 2010;2010:812424doi: 10.1155/2010/812424.
Kim, S. C., Natarajan-Ame, S., Lioure, B., Chenard, M. P., Duclos, B., Herbrecht, R., & Bergerat, J. P. (2010). Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up. Journal of oncology, 2010812424. https://doi.org/10.1155/2010/812424
Kim, Stefano C H, et al. "Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up." Journal of oncology vol. 2010 (2010): 812424. doi: https://doi.org/10.1155/2010/812424
Kim SC, Natarajan-Ame S, Lioure B, Chenard MP, Duclos B, Herbrecht R, Bergerat JP. Successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up. J Oncol. 2010;2010:812424. doi: 10.1155/2010/812424. Epub 2010 Apr 29. PMID: 20454648; PMCID: PMC2862322.
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The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder.

Neuropsychobiology

Hebbrecht K, Morrens M, Giltay EJ, van Nuijs ALN, Sabbe B, van den Ameele S.
PMID: 34883494
Neuropsychobiology. 2021 Dec 09;1-8. doi: 10.1159/000520152. Epub 2021 Dec 09.

INTRODUCTION: Chronic low-grade inflammation is suggested to play a pathophysiological role in bipolar disorder (BD) and its related cognitive dysfunctions. Although kynurenine (KYN) pathway metabolites are key inflammatory mediators, studies investigating the association between KYN metabolism and cognition in...

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Hebbrecht K, Morrens M, Giltay EJ, et al. The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder. Neuropsychobiology. 2021;1-8doi: 10.1159/000520152.
Hebbrecht, K., Morrens, M., Giltay, E. J., van Nuijs, A. L. N., Sabbe, B., & van den Ameele, S. (2021). The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder. Neuropsychobiology, 1-8. https://doi.org/10.1159/000520152
Hebbrecht, Kaat, et al. "The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder." Neuropsychobiology vol. (2021): 1-8. doi: https://doi.org/10.1159/000520152
Hebbrecht K, Morrens M, Giltay EJ, van Nuijs ALN, Sabbe B, van den Ameele S. The Role of Kynurenines in Cognitive Dysfunction in Bipolar Disorder. Neuropsychobiology. 2021 Dec 09;1-8. doi: 10.1159/000520152. Epub 2021 Dec 09. PMID: 34883494.
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Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020.

Emerging infectious diseases

Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F.
PMID: 34932452
Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543.

Rare fungal pathogens are emerging as agents of invasive fungal infections. We analyzed 13 cases of fungal infections caused by Kazachstania (Arxiozyma) spp. in Strasbourg University Hospital, Strasbourg, France. Among the cases, 4 patients had proven fungal disease (3...

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Kaeuffer C, Baldacini M, Ruge T, et al. Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerg Infect Dis. 2022;28(1):29-34doi: 10.3201/eid2801.211543.
Kaeuffer, C., Baldacini, M., Ruge, T., Ruch, Y., Zhu, Y. J., De Cian, M., Philouze, G., Bachellier, P., Denis, J., Lefebvre, N., Schneider, F., Hansmann, Y., Letscher-Bru, V., Herbrecht, R., Sabou, M., & Danion, F. (2022). Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerging infectious diseases, 28(1), 29-34. https://doi.org/10.3201/eid2801.211543
Kaeuffer, Charlotte, et al. "Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020." Emerging infectious diseases vol. 28,1 (2022): 29-34. doi: https://doi.org/10.3201/eid2801.211543
Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F. Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543. PMID: 34932452; PMCID: PMC8714217.
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Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020.

Emerging infectious diseases

Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F.
PMID: 34932452
Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543.

Rare fungal pathogens are emerging as agents of invasive fungal infections. We analyzed 13 cases of fungal infections caused by Kazachstania (Arxiozyma) spp. in Strasbourg University Hospital, Strasbourg, France. Among the cases, 4 patients had proven fungal disease (3...

Cite
Kaeuffer C, Baldacini M, Ruge T, et al. Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerg Infect Dis. 2022;28(1):29-34doi: 10.3201/eid2801.211543.
Kaeuffer, C., Baldacini, M., Ruge, T., Ruch, Y., Zhu, Y. J., De Cian, M., Philouze, G., Bachellier, P., Denis, J., Lefebvre, N., Schneider, F., Hansmann, Y., Letscher-Bru, V., Herbrecht, R., Sabou, M., & Danion, F. (2022). Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerging infectious diseases, 28(1), 29-34. https://doi.org/10.3201/eid2801.211543
Kaeuffer, Charlotte, et al. "Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020." Emerging infectious diseases vol. 28,1 (2022): 29-34. doi: https://doi.org/10.3201/eid2801.211543
Kaeuffer C, Baldacini M, Ruge T, Ruch Y, Zhu YJ, De Cian M, Philouze G, Bachellier P, Denis J, Lefebvre N, Schneider F, Hansmann Y, Letscher-Bru V, Herbrecht R, Sabou M, Danion F. Fungal Infections Caused by Kazachstania spp., Strasbourg, France, 2007-2020. Emerg Infect Dis. 2022 Jan;28(1):29-34. doi: 10.3201/eid2801.211543. PMID: 34932452.
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Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases.

Drugs - real world outcomes

Mourot-Cottet R, Maloisel F, Séverac F, Keller O, Vogel T, Tebacher M, Weber JC, Kaltenbach G, Gottenberg JE, Goichot B, Sibilia J, Korganow AS, Herbrecht R, Andrès E.
PMID: 27747601
Drugs Real World Outcomes. 2016 Dec;3(4):393-399. doi: 10.1007/s40801-016-0091-4.

BACKGROUND: Little data is currently available in the literature on neutropenia and agranulocytosis in the elderly, and, to our knowledge, idiosyncratic drug-induced agranulocytosis is particularly poorly covered, or not at all.OBJECTIVE: We herein describe the clinical picture and outcome...

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Mourot-Cottet R, Maloisel F, Séverac F, et al. Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases. Drugs Real World Outcomes. 2016;3(4):393-399doi: 10.1007/s40801-016-0091-4.
Mourot-Cottet, R., Maloisel, F., Séverac, F., Keller, O., Vogel, T., Tebacher, M., Weber, J. C., Kaltenbach, G., Gottenberg, J. E., Goichot, B., Sibilia, J., Korganow, A. S., Herbrecht, R., & Andrès, E. (2016). Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases. Drugs - real world outcomes, 3(4), 393-399. https://doi.org/10.1007/s40801-016-0091-4
Mourot-Cottet, Rachel, et al. "Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases." Drugs - real world outcomes vol. 3,4 (2016): 393-399. doi: https://doi.org/10.1007/s40801-016-0091-4
Mourot-Cottet R, Maloisel F, Séverac F, Keller O, Vogel T, Tebacher M, Weber JC, Kaltenbach G, Gottenberg JE, Goichot B, Sibilia J, Korganow AS, Herbrecht R, Andrès E. Idiosyncratic Drug-Induced Severe Neutropenia and Agranulocytosis in Elderly Patients (≥75 years): A Monocentric Cohort Study of 61 Cases. Drugs Real World Outcomes. 2016 Dec;3(4):393-399. doi: 10.1007/s40801-016-0091-4. PMID: 27747601; PMCID: PMC5127888.
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