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Showing 1 to 12 of 22 entries
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Autophagy and mesenchymal cell fibrogenesis.

Biochimica et biophysica acta

Hilscher M, Hernandez-Gea V, Friedman SL.
PMID: 23142802
Biochim Biophys Acta. 2012 Jul;1831(7):972-8. doi: 10.1016/j.bbadis.2012.11.001. Epub 2012 Nov 09.

Autophagy is a catabolic pathway essential for cellular energy homeostasis that involves the self-degradation of intracellular components in lysosomes. This process has been implicated in the pathophysiology of many human disorders, including infection, cancer, and fibrosis. Autophagy is also...

The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.

NeuroImage. Clinical

Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM.
PMID: 34952353
Neuroimage Clin. 2021 Dec 20;33:102922. doi: 10.1016/j.nicl.2021.102922. Epub 2021 Dec 20.

BACKGROUND: Posttraumatic Stress Disorder (PTSD) is commonly treated with exposure-based cognitive therapies that are based on the principles of fear acquisition and extinction learning. Elevations in one of the major endocannabinoids (anandamide) either via inhibition of the primary degrading...

The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.

NeuroImage. Clinical

Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM.
PMID: 34952353
Neuroimage Clin. 2021 Dec 20;33:102922. doi: 10.1016/j.nicl.2021.102922. Epub 2021 Dec 20.

BACKGROUND: Posttraumatic Stress Disorder (PTSD) is commonly treated with exposure-based cognitive therapies that are based on the principles of fear acquisition and extinction learning. Elevations in one of the major endocannabinoids (anandamide) either via inhibition of the primary degrading...

The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.

NeuroImage. Clinical

Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM.
PMID: 34952353
Neuroimage Clin. 2021 Dec 20;33:102922. doi: 10.1016/j.nicl.2021.102922. Epub 2021 Dec 20.

BACKGROUND: Posttraumatic Stress Disorder (PTSD) is commonly treated with exposure-based cognitive therapies that are based on the principles of fear acquisition and extinction learning. Elevations in one of the major endocannabinoids (anandamide) either via inhibition of the primary degrading...

Congestive hepatopathy.

Clinical liver disease

Hilscher M, Sanchez W.
PMID: 31041066
Clin Liver Dis (Hoboken). 2016 Oct 02;8(3):68-71. doi: 10.1002/cld.573. eCollection 2016 Sep.

No abstract available.

Elevated serum levels of methylglyoxal are associated with impaired liver function in patients with liver cirrhosis.

Scientific reports

Michel M, Hess C, Kaps L, Kremer WM, Hilscher M, Galle PR, Moehler M, Schattenberg JM, Wörns MA, Labenz C, Nagel M.
PMID: 34654829
Sci Rep. 2021 Oct 15;11(1):20506. doi: 10.1038/s41598-021-00119-7.

Methylglyoxal (MGO) is a highly reactive dicarbonyl species that forms advanced glycation end products (AGEs). The binding of these AGEs to their receptor (RAGE) causes and sustains severe inflammation. Systemic inflammation is postulated to be a major driver in...

The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.

NeuroImage. Clinical

Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM.
PMID: 34952353
Neuroimage Clin. 2021 Dec 20;33:102922. doi: 10.1016/j.nicl.2021.102922. Epub 2021 Dec 20.

BACKGROUND: Posttraumatic Stress Disorder (PTSD) is commonly treated with exposure-based cognitive therapies that are based on the principles of fear acquisition and extinction learning. Elevations in one of the major endocannabinoids (anandamide) either via inhibition of the primary degrading...

The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD.

NeuroImage. Clinical

Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM.
PMID: 34952353
Neuroimage Clin. 2021 Dec 20;33:102922. doi: 10.1016/j.nicl.2021.102922. Epub 2021 Dec 20.

BACKGROUND: Posttraumatic Stress Disorder (PTSD) is commonly treated with exposure-based cognitive therapies that are based on the principles of fear acquisition and extinction learning. Elevations in one of the major endocannabinoids (anandamide) either via inhibition of the primary degrading...

More on DNR: Agonizing decisions, haunting questions.

Journal of emergency nursing

Heilicser B.
PMID: 9925670
J Emerg Nurs. 1999 Feb;25(1):5. doi: 10.1016/s0099-1767(99)70140-6.

No abstract available.

Hepatology Highlights.

Hepatology (Baltimore, Md.)

Amir M, Vora RS, Tafesh ZH, Jesudian A, Gupta V, Schwartz RE, Russo N, Danford CJ, Lau DTY, Brown RS, Jalan-Sakrikar N, Maiers JL, Sharma R, Fortune BE, Hilscher M, Aseem SO.
PMID: 31661168
Hepatology. 2019 Nov;70(5):1497-1499. doi: 10.1002/hep.30995.

No abstract available.

Functional imaging correlates of childhood trauma: A qualitative review of past research and emerging trends.

Pharmacology, biochemistry, and behavior

Ross MC, Heilicher M, Cisler JM.
PMID: 34780877
Pharmacol Biochem Behav. 2021 Dec;211:173297. doi: 10.1016/j.pbb.2021.173297. Epub 2021 Nov 12.

Childhood trauma exposure is common and is associated with poor clinical outcomes in adolescence along with mental health and sociodemographic challenges in adulthood. While many strategies exist to investigate the biological imprint of childhood trauma exposure, functional neuroimaging is...

Evaluation of IL-6 for Stepwise Diagnosis of Minimal Hepatic Encephalopathy in Patients With Liver Cirrhosis.

Hepatology communications

Gairing SJ, Anders J, Kaps L, Nagel M, Michel M, Kremer WM, Hilscher M, Galle PR, Schattenberg JM, Wörns MA, Labenz C.
PMID: 35032100
Hepatol Commun. 2022 Jan 14; doi: 10.1002/hep4.1883. Epub 2022 Jan 14.

Diagnosis of minimal hepatic encephalopathy (MHE) requires psychometric testing, which is time-consuming and often neglected in clinical practice. Elevated Interleukin-6 (IL-6) serum levels have been linked to MHE. The aim of this study was to investigate the usefulness of...

Showing 1 to 12 of 22 entries