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Showing 1 to 12 of 821 entries
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Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Katakami N, Mita T, Yoshii H, Shiraiwa T, Yasuda T, Okada Y, Umayahara Y, Kaneto H, Osonoi T, Yamamoto T, Kuribayashi N, Maeda K, Yokoyama H, Kosugi K, Ohtoshi K, Hayashi I, Sumitani S, Tsugawa M, Ohashi M, Taki H, Nakamura T, Kawashima S, Sato Y, Watada H, Shimomura I.
PMID: 28864997
Diabetes Ther. 2017 Oct;8(5):999-1013. doi: 10.1007/s13300-017-0292-1. Epub 2017 Sep 01.

INTRODUCTION: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are anti-diabetic agents that improve glycemic control with a low risk of hypoglycemia and ameliorate a variety of cardiovascular risk factors. The aim of the ongoing study described herein is to investigate the preventive...

Spontaneously Resolved Recurrent Cervical Epidural Hematoma in a 37-Week Primigravida.

Global spine journal

Iwatsuki K, Deguchi M, Hirata H, Kanamono T.
PMID: 26430600
Global Spine J. 2015 Oct;5(5):e44-7. doi: 10.1055/s-0034-1398489. Epub 2015 Jan 07.

Study Design Case report. Objective To describe a patient with a recurrent spontaneous spinal epidural hematoma (SSEH) during pregnancy that had spontaneous remission. Methods A 27-year-old primigravida at 37 weeks' gestation suddenly felt a strong left shoulder pain without...

Complete Genome Sequence of a Novel GV.2 Sapovirus Strain, NGY-1, Detected from a Suspected Foodborne Gastroenteritis Outbreak.

Genome announcements

Shibata S, Sekizuka T, Kodaira A, Kuroda M, Haga K, Doan YH, Takai-Todaka R, Katayama K, Wakita T, Oka T, Hirata H.
PMID: 25676762
Genome Announc. 2015 Feb 12;3(1). doi: 10.1128/genomeA.01553-14.

Sapoviruses, members of the family Caliciviridae, are genetically highly diverse. We report here the first complete genome sequence of a genogroup V genotype 2 sapovirus strain, NGY-1, detected from fecal samples of a suspected foodborne gastroenteritis outbreak, determined using...

Synthesis of Optically Active 1,4-Thiazane-3-carboxylic Acid via Optical Resolution by Preferential Crystallization of (RS)-2-Amino-3-[(2-chloroethyl)sulfanyl]propanoic Acid Hydrochloride.

Bioscience, biotechnology, and biochemistry

Shiraiwa T, Tadokoro K, Tanaka H, Nanba K, Yokono N, Shibazaki K, Kubo M, Kurokawa H.
PMID: 27392398
Biosci Biotechnol Biochem. 1998;62(12):2382-7. doi: 10.1271/bbb.62.2382.

Optically active 1,4-thiazane-3-carboxylic acid [TCA] was synthesized from cysteine via optical resolution by preferential crystallization. The intermediate (RS)-2-amino-3-[(2-chloroethyl)sulfanyl]propanoic acid hydrochlo-ride [(RS)-ACS•HCl] was found to exist as a conglomerate based on its melting point, solubility and IR spectrum. (RS)-ACS•HCl was...

Radial diffusion and penetration of gas molecules and aerosol particles through laminar flow reactors, denuders, and sampling tubes.

Analytical chemistry

Knopf DA, Pöschl U, Shiraiwa M.
PMID: 25744622
Anal Chem. 2015 Apr 07;87(7):3746-54. doi: 10.1021/ac5042395. Epub 2015 Mar 16.

Flow reactors, denuders, and sampling tubes are essential tools for many applications in analytical and physical chemistry and engineering. We derive a new method for determining radial diffusion effects and the penetration or transmission of gas molecules and aerosol...

Giving social support to outside family may be a desirable buffer against depressive symptoms in community-dwelling older adults: Japan gerontological evaluation study.

BioPsychoSocial medicine

Tsuboi H, Hirai H, Kondo K.
PMID: 27226808
Biopsychosoc Med. 2016 May 24;10:18. doi: 10.1186/s13030-016-0064-6. eCollection 2016.

BACKGROUND: Depression is the leading cause of impaired quality of life and burden upon societies. Social supports can buffer against depressive symptoms effectively. The aim of this study is to determine the type of social support to have a...

Condensed-phase biogenic-anthropogenic interactions with implications for cold cloud formation.

Faraday discussions

Charnawskas JC, Alpert PA, Lambe AT, Berkemeier T, O'Brien RE, Massoli P, Onasch TB, Shiraiwa M, Moffet RC, Gilles MK, Davidovits P, Worsnop DR, Knopf DA.
PMID: 28574555
Faraday Discuss. 2017 Aug 24;200:165-194. doi: 10.1039/c7fd00010c.

Anthropogenic and biogenic gas emissions contribute to the formation of secondary organic aerosol (SOA). When present, soot particles from fossil fuel combustion can acquire a coating of SOA. We investigate SOA-soot biogenic-anthropogenic interactions and their impact on ice nucleation...

Complete Genome Sequence of Super Biofilm-Elaborating .

Genome announcements

Yu L, Hisatsune J, Hirakawa H, Mizumachi E, Toyoda A, Yahara K, Sugai M.
PMID: 29025936
Genome Announc. 2017 Oct 12;5(41). doi: 10.1128/genomeA.01043-17.

No abstract available.

Two-Step Synthesis of Boron-Fused Double Helicenes.

Journal of the American Chemical Society

Katayama T, Nakatsuka S, Hirai H, Yasuda N, Kumar J, Kawai T, Hatakeyama T.
PMID: 27077723
J Am Chem Soc. 2016 Apr 27;138(16):5210-3. doi: 10.1021/jacs.6b01674. Epub 2016 Apr 14.

Novel boron-fused double [5]helicenes were synthesized from hexabromobenzene in two steps via Hart reaction and demethylative cyclization. The parent helicene shows excellent ambipolar conductivity, which can be explained by unique 3D π-stacking with a brickwork arrangement. Moreover, the introduction...

New LaMAsH(x) (M = Co, Ni, or Cu) arsenides with covalent M-H chains.

Journal of the American Chemical Society

Mizoguchi H, Park S, Hiraka H, Ikeda K, Otomo T, Hosono H.
PMID: 25438068
J Am Chem Soc. 2014 Dec 17;136(50):17390-3. doi: 10.1021/ja509965z. Epub 2014 Dec 09.

A new series of tetragonal LaPtSi-type mixed-anion arsenides, LaMAsH(x) (M = Co, Ni, or Cu), has been synthesized using high-temperature and high-pressure techniques. The crystal structure of these intermetallic compounds determined via powder neutron diffraction is composed of a...

Use of color Doppler ultrasonography to measure thyroid blood flow and differentiate graves' disease from painless thyroiditis.

European thyroid journal

Hiraiwa T, Tsujimoto N, Tanimoto K, Terasaki J, Amino N, Hanafusa T.
PMID: 24783050
Eur Thyroid J. 2013 Jun;2(2):120-6. doi: 10.1159/000350560. Epub 2013 May 15.

BACKGROUNDS: Color Doppler ultrasonography (CDU) has not yet been established as a method to investigate the pathogenesis of thyrotoxicosis.OBJECTIVES: Our first objective was to determine whether the measurement of peak systolic blood-flow velocity in the superior thyroid artery (STV)...

Regular insulin, rather than rapid-acting insulin, is a suitable choice for premeal bolus insulin in lean patients with type 2 diabetes mellitus.

Journal of diabetes investigation

Kuroda A, Kaneto H, Kawashima S, Sakamoto K, Takahara M, Shiraiwa T, Yasuda T, Katakami N, Matsuoka TA, Shimomura I, Matsuhisa M.
PMID: 24843634
J Diabetes Investig. 2013 Jan 29;4(1):78-81. doi: 10.1111/j.2040-1124.2012.00231.x. Epub 2012 Aug 21.

The aim of the present study was to compare the usefulness of premeal rapid-acting and regular insulin in type 2 diabetes patients. A total of 56 type 2 diabetic patients were investigated during hospitalization. Premeal rapid-acting insulin was applied...

Showing 1 to 12 of 821 entries