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Showing 1 to 12 of 44 entries
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T cell progenitor therapy-facilitated thymopoiesis depends upon thymic input and continued thymic microenvironment interaction.

JCI insight

Smith MJ, Reichenbach DK, Parker SL, Riddle MJ, Mitchell J, Osum KC, Mohtashami M, Stefanski HE, Fife BT, Bhandoola A, Hogquist KA, Holländer GA, Zúñiga-Pflücker JC, Tolar J, Blazar BR.
PMID: 28515359
JCI Insight. 2017 May 18;2(10). doi: 10.1172/jci.insight.92056. eCollection 2017 May 18.

Infusion of in vitro-derived T cell progenitor (proT) therapy with hematopoietic stem cell transplant aids the recovery of the thymus damaged by total body irradiation. To understand the interaction between proTs and the thymic microenvironment, WT mice were lethally...

Inhibition of anthocyanin formation in seedlings and flowers by the enantiomers of α-aminooxy-β-phenylpropionic acid and their N-benzyloxycarbonyl derivatives.

Planta

Amrhein N, Holländer H.
PMID: 24407328
Planta. 1979 Jan;144(4):385-9. doi: 10.1007/BF00391582.

Both enantiomers of α-aminooxy-β-phenylpropionic acid (AOPP), potent inhibitors of L-phenylalanine ammonia-lyase, and their N-benzyloxycarbonyl (N-BOC) derivatives inhibit anthocyanin formation in developing flowers of Ipomoea tricolor Cav. and Catharanthus roseus Don. as well as in seedlings of Brassica oleracea var....

The physician, the patient, and cancer.

The Illinois medical journal

HOLLENDER MH.
PMID: 13232681
Ill Med J. 1955 Jan;107(1):20-3.

No abstract available.

The Site of the Inhibition of the Shikimate Pathway by Glyphosate: I. INHIBITION BY GLYPHOSATE OF PHENYLPROPANOID SYNTHESIS IN BUCKWHEAT (FAGOPYRUM ESCULENTUM MOENCH) .

Plant physiology

Holländer H, Amrhein N.
PMID: 16661534
Plant Physiol. 1980 Nov;66(5):823-9. doi: 10.1104/pp.66.5.823.

The nonselective herbicide glyphosate (n-[phosphonomethyl]glycine) inhibited the light-induced accumulation of phenylpropanoid substances (chlorogenic acid, procyanidin, rutin, anthocyanin) in etiolated buckwheat hypocotyls 90% at 1 millimolar. Structurally related compounds, such as n,n-bis[phosphonomethyl]glycine, aminomethylphosphonate, methylglycine, and iminodiacetate, had little or no...

Developing educators, investigators, and leaders during internal medicine residency: the area of distinction program.

Journal of graduate medical education

Kohlwes RJ, Cornett P, Dandu M, Julian K, Vidyarthi A, Minichiello T, Shunk R, Jain S, Harleman E, Ranji S, Sharpe B, O'Sullivan P, Hollander H.
PMID: 23205204
J Grad Med Educ. 2011 Dec;3(4):535-40. doi: 10.4300/JGME-D-11-00029.1.

BACKGROUND: Professional organizations have called for individualized training approaches, as well as for opportunities for resident scholarship, to ensure that internal medicine residents have sufficient knowledge and experience to make informed career choices.CONTEXT AND PURPOSE: To address these training...

Characterization of non-stoichiometric co-sputtered Ba0.6Sr0.4(Ti (1-x)Fe(x))(1+x)O(3-δ) thin films for tunable passive microwave applications.

Analytical and bioanalytical chemistry

Stemme F, Geßwein H, Drahus MD, Holländer B, Azucena C, Binder JR, Eichel RA, Haußelt J, Bruns M.
PMID: 22012210
Anal Bioanal Chem. 2012 May;403(3):643-50. doi: 10.1007/s00216-011-5435-z. Epub 2011 Oct 20.

The fabrication of novel iron-doped barium strontium titanate thin films by means of radio frequency (RF) magnetron co-sputtering is shown. Investigations of the elemental composition and the dopant distribution in the thin films obtained by X-ray photoelectron spectroscopy, Rutherford...

Evaluating and forecasting movement patterns of magnetically driven microbeads in complex geometries.

Scientific reports

Klingbeil F, Block F, Sajjad U, Holländer RB, Deshpande S, McCord J.
PMID: 32472020
Sci Rep. 2020 May 29;10(1):8761. doi: 10.1038/s41598-020-65380-8.

The manipulation of superparamagnetic microbeads for lab-on-a-chip applications relies on the steering of microbeads across an altering stray field landscape on top of soft magnetic parent structures. Using ab initio principles, we show three-dimensional simulations forecasting the controlled movement...

Thymus Extracellular Matrix-Derived Scaffolds Support Graft-Resident Thymopoiesis and Long-Term In Vitro Culture of Adult Thymic Epithelial Cells.

Advanced functional materials

Asnaghi MA, Barthlott T, Gullotta F, Strusi V, Amovilli A, Hafen K, Srivastava G, Oertle P, Toni R, Wendt D, Holländer GA, Martin I.
PMID: 34539304
Adv Funct Mater. 2021 May 17;31(20):2010747. doi: 10.1002/adfm.202010747. Epub 2021 Mar 12.

The thymus provides the physiological microenvironment critical for the development of T lymphocytes, the cells that orchestrate the adaptive immune system to generate an antigen-specific response. A diverse population of stroma cells provides surface-bound and soluble molecules that orchestrate...

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.

Science advances

Rota IA, Handel AE, Maio S, Klein F, Dhalla F, Deadman ME, Cheuk S, Newman JA, Michaels YS, Zuklys S, Prevot N, Hublitz P, Charles PD, Gkazi AS, Adamopoulou E, Qasim W, Davies EG, Hanson I, Pagnamenta AT, Camps C, Dreau HM, White A, James K, Fischer R, Gileadi O, Taylor JC, Fulga T, Lagerholm BC, Anderson G, Sezgin E, Holländer GA.
PMID: 34860543
Sci Adv. 2021 Dec 03;7(49):eabj9247. doi: 10.1126/sciadv.abj9247. Epub 2021 Dec 03.

[Figure: see text].

Immunotherapy for B-cell lymphoma: current status and prospective advances.

Frontiers in immunology

Hollander N.
PMID: 22566889
Front Immunol. 2012 Jan 24;3:3. doi: 10.3389/fimmu.2012.00003. eCollection 2012.

Therapy for non-Hodgkin's lymphoma has progressed significantly over the last decades. However, the majority of patients remain incurable, and novel therapies are needed. Because immunotherapy ideally offers target selectivity, an ever increasing number of immunotherapies, both passive and active,...

Minimally Invasive Cholecystectomy: Transvaginal or Transabdominal Approach-Which Technique Is Preferred by Female Hospital Employees?.

Journal of laparoendoscopic & advanced surgical techniques. Part A

Holländer S, von Heesen M, von Heesen A, Spiliotis AE, Gäbelein G, Scherber PR, Glanemann M.
PMID: 34283667
J Laparoendosc Adv Surg Tech A. 2021 Jul 19; doi: 10.1089/lap.2021.0389. Epub 2021 Jul 19.

No abstract available.

Altered N-Linked Glycosylation in Follicular Lymphoma and Chronic Lymphocytic Leukemia: Involvement in Pathogenesis and Potential Therapeutic Targeting.

Frontiers in immunology

Hollander N, Haimovich J.
PMID: 28824637
Front Immunol. 2017 Aug 02;8:912. doi: 10.3389/fimmu.2017.00912. eCollection 2017.

B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes. Oligosaccharides added to the acquired sites are unusually of the...

Showing 1 to 12 of 44 entries