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Showing 1 to 12 of 16 entries
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Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder.

Frontiers in psychiatry

Schmidt U, Herrmann L, Hagl K, Novak B, Huber C, Holsboer F, Wotjak CT, Buell DR.
PMID: 23847554
Front Psychiatry. 2013 Jul 10;4:66. doi: 10.3389/fpsyt.2013.00066. eCollection 2013.

MicroRNAs (miRNA) are a class of small non-coding RNAs that have recently emerged as epigenetic modulators of gene expression in psychiatric diseases like schizophrenia and major depression. So far, miRNAs have neither been studied in patients suffering from posttraumatic...

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Schmidt U, Herrmann L, Hagl K, et al. Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Front Psychiatry. 2013;4:66doi: 10.3389/fpsyt.2013.00066.
Schmidt, U., Herrmann, L., Hagl, K., Novak, B., Huber, C., Holsboer, F., Wotjak, C. T., & Buell, D. R. (2013). Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Frontiers in psychiatry, 466. https://doi.org/10.3389/fpsyt.2013.00066
Schmidt, Ulrike, et al. "Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder." Frontiers in psychiatry vol. 4 (2013): 66. doi: https://doi.org/10.3389/fpsyt.2013.00066
Schmidt U, Herrmann L, Hagl K, Novak B, Huber C, Holsboer F, Wotjak CT, Buell DR. Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Front Psychiatry. 2013 Jul 10;4:66. doi: 10.3389/fpsyt.2013.00066. eCollection 2013. PMID: 23847554; PMCID: PMC3706988.
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Time to bid goodbye.

Journal of psychiatric research

Holsboer F, Schatzberg AF.
PMID: 31898945
J Psychiatr Res. 2020 Mar;122:A1. doi: 10.1016/j.jpsychires.2019.11.020. Epub 2019 Dec 04.

No abstract available.

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Holsboer F, Schatzberg AF. Time to bid goodbye. J Psychiatr Res. 2019;122:A1doi: 10.1016/j.jpsychires.2019.11.020.
Holsboer, F., & Schatzberg, A. F. (2020). Time to bid goodbye. Journal of psychiatric research, 122A1. https://doi.org/10.1016/j.jpsychires.2019.11.020
Holsboer, Florian, and Schatzberg, Alan F. "Time to bid goodbye." Journal of psychiatric research vol. 122 (2020): A1. doi: https://doi.org/10.1016/j.jpsychires.2019.11.020
Holsboer F, Schatzberg AF. Time to bid goodbye. J Psychiatr Res. 2020 Mar;122:A1. doi: 10.1016/j.jpsychires.2019.11.020. Epub 2019 Dec 04. PMID: 31898945.
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Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men.

Journal of sleep research

Friess E, V Bardeleben U, Wiedemann K, Lauer CJ, Holsboer F.
PMID: 10607111
J Sleep Res. 1994 Jun;3(2):73-79. doi: 10.1111/j.1365-2869.1994.tb00110.x.

This study investigates the short-term effects of pulsatile cortisol administrations upon sleep electroencephalogram (EEG) and spontaneous release of growth hormone (GH) in humans. Ten young healthy male volunteers received intravenous injections of either placebo or cortisol every 60 min...

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Friess E, V Bardeleben U, Wiedemann K, et al. Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men. J Sleep Res. 1994;3(2):73-79doi: 10.1111/j.1365-2869.1994.tb00110.x.
Friess, E., V Bardeleben U, Wiedemann, K., Lauer, C. J., & Holsboer, F. (1994). Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men. Journal of sleep research, 3(2), 73-79. https://doi.org/10.1111/j.1365-2869.1994.tb00110.x
Friess, et al. "Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men." Journal of sleep research vol. 3,2 (1994): 73-79. doi: https://doi.org/10.1111/j.1365-2869.1994.tb00110.x
Friess E, V Bardeleben U, Wiedemann K, Lauer CJ, Holsboer F. Effects of pulsatile cortisol infusion on sleep-EEG and nocturnal growth hormone release in healthy men. J Sleep Res. 1994 Jun;3(2):73-79. doi: 10.1111/j.1365-2869.1994.tb00110.x. PMID: 10607111.
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On the role of corticotropin-releasing hormone receptors in anxiety and depression.

Dialogues in clinical neuroscience

Reul JM, Holsboer F.
PMID: 22033745
Dialogues Clin Neurosci. 2002 Mar;4(1):31-46.

On the basis of extensive basic and clinical studies, corticotropin-releasing hormone (CRH) and its related family members are considered to play a pivotal role in stress-related disorders, such as anxiety and depression. CRH is regarded as the principal mediator...

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Reul JM, Holsboer F. On the role of corticotropin-releasing hormone receptors in anxiety and depression. Dialogues Clin Neurosci. 2002;4(1):31-46
Reul, J. M., & Holsboer, F. (2002). On the role of corticotropin-releasing hormone receptors in anxiety and depression. Dialogues in clinical neuroscience, 4(1), 31-46.
Reul, Johannes M H M, and Holsboer, Florian. "On the role of corticotropin-releasing hormone receptors in anxiety and depression." Dialogues in clinical neuroscience vol. 4,1 (2002): 31-46.
Reul JM, Holsboer F. On the role of corticotropin-releasing hormone receptors in anxiety and depression. Dialogues Clin Neurosci. 2002 Mar;4(1):31-46. PMID: 22033745; PMCID: PMC3181666.
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CRHR1 antagonists as novel treatment strategies.

CNS spectrums

Holsboer F.
PMID: 15573022
CNS Spectr. 2001 Jul;6(7):590-4. doi: 10.1017/s1092852900002133.

Research has provided considerable evidence for the hypothesis that corticotropin-releasing hormone (CRH), the key central coordinator of stress-hormone homeostasis, also plays a role in the development and course of depression and anxiety disorders. Studies using animal models of anxiety,...

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Holsboer F. CRHR1 antagonists as novel treatment strategies. CNS Spectr. 2001;6(7):590-4doi: 10.1017/s1092852900002133.
Holsboer, F. (2001). CRHR1 antagonists as novel treatment strategies. CNS spectrums, 6(7), 590-4. https://doi.org/10.1017/s1092852900002133
Holsboer, F. "CRHR1 antagonists as novel treatment strategies." CNS spectrums vol. 6,7 (2001): 590-4. doi: https://doi.org/10.1017/s1092852900002133
Holsboer F. CRHR1 antagonists as novel treatment strategies. CNS Spectr. 2001 Jul;6(7):590-4. doi: 10.1017/s1092852900002133. PMID: 15573022.
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Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression.

Journal of neuroendocrinology

Bardeleben U, Holsboer F.
PMID: 19210420
J Neuroendocrinol. 1989 Dec 01;1(6):485-8. doi: 10.1111/j.1365-2826.1989.tb00150.x.

Abstract We administered a combined dexamethasone-human corticotrophin-releasing hormone (hCRH) challenge test to 14 in-patients with a major depressive episode and to 14 age-matched controls. After pretreatment with 1.5 mg dexamethasone at 2300 h the day before, 100 mug hCRH...

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Bardeleben U, Holsboer F. Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression. J Neuroendocrinol. 1989;1(6):485-8doi: 10.1111/j.1365-2826.1989.tb00150.x.
Bardeleben, U., & Holsboer, F. (1989). Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression. Journal of neuroendocrinology, 1(6), 485-8. https://doi.org/10.1111/j.1365-2826.1989.tb00150.x
Bardeleben, U, and Holsboer, F. "Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression." Journal of neuroendocrinology vol. 1,6 (1989): 485-8. doi: https://doi.org/10.1111/j.1365-2826.1989.tb00150.x
Bardeleben U, Holsboer F. Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression. J Neuroendocrinol. 1989 Dec 01;1(6):485-8. doi: 10.1111/j.1365-2826.1989.tb00150.x. PMID: 19210420.
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Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis.

Proteomics. Clinical applications

Jastorff AM, Haegler K, Maccarrone G, Holsboer F, Weber F, Ziemssen T, Turck CW.
PMID: 21136950
Proteomics Clin Appl. 2009 Nov;3(11):1273-87. doi: 10.1002/prca.200800155. Epub 2009 Oct 13.

Multiple sclerosis is characterized by inflammatory demyelination and axonal loss as pathophysiological correlates of relapsing activity and progressive development of clinical disability. The molecular processes involved in this pathogenesis are still unclear as they are quite complex and heterogeneous....

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Jastorff AM, Haegler K, Maccarrone G, et al. Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Proteomics Clin Appl. 2009;3(11):1273-87doi: 10.1002/prca.200800155.
Jastorff, A. M., Haegler, K., Maccarrone, G., Holsboer, F., Weber, F., Ziemssen, T., & Turck, C. W. (2009). Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Proteomics. Clinical applications, 3(11), 1273-87. https://doi.org/10.1002/prca.200800155
Jastorff, Archana M, et al. "Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis." Proteomics. Clinical applications vol. 3,11 (2009): 1273-87. doi: https://doi.org/10.1002/prca.200800155
Jastorff AM, Haegler K, Maccarrone G, Holsboer F, Weber F, Ziemssen T, Turck CW. Regulation of proteins mediating neurodegeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Proteomics Clin Appl. 2009 Nov;3(11):1273-87. doi: 10.1002/prca.200800155. Epub 2009 Oct 13. PMID: 21136950.
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Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression.

Psychoneuroendocrinology

Hennings JM, Ising M, Uhr M, Holsboer F, Lucae S.
PMID: 34090135
Psychoneuroendocrinology. 2021 Sep;131:105286. doi: 10.1016/j.psyneuen.2021.105286. Epub 2021 May 28.

The neuropathological mechanisms leading to suicidality are still unknown, which, in view of an annual toll of around 1 million completed suicides constitutes an urgent clinical and societal problem. Alterations of stress hormone (ACTH and cortisol, representing the activity...

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Hennings JM, Ising M, Uhr M, et al. Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression. Psychoneuroendocrinology. 2021;131:105286doi: 10.1016/j.psyneuen.2021.105286.
Hennings, J. M., Ising, M., Uhr, M., Holsboer, F., & Lucae, S. (2021). Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression. Psychoneuroendocrinology, 131105286. https://doi.org/10.1016/j.psyneuen.2021.105286
Hennings, Johannes M, et al. "Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression." Psychoneuroendocrinology vol. 131 (2021): 105286. doi: https://doi.org/10.1016/j.psyneuen.2021.105286
Hennings JM, Ising M, Uhr M, Holsboer F, Lucae S. Effects of weariness of life, suicide ideations and suicide attempt on HPA axis regulation in depression. Psychoneuroendocrinology. 2021 Sep;131:105286. doi: 10.1016/j.psyneuen.2021.105286. Epub 2021 May 28. PMID: 34090135.
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Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels.

Frontiers in cellular neuroscience

Kratzer S, Mattusch C, Metzger MW, Dedic N, Noll-Hussong M, Kafitz KW, Eder M, Deussing JM, Holsboer F, Kochs E, Rammes G.
PMID: 23882180
Front Cell Neurosci. 2013 Jul 19;7:91. doi: 10.3389/fncel.2013.00091. eCollection 2013.

Corticotropin-releasing hormone (CRH) plays an important role in a substantial number of patients with stress-related mental disorders, such as anxiety disorders and depression. CRH has been shown to increase neuronal excitability in the hippocampus, but the underlying mechanisms are...

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Kratzer S, Mattusch C, Metzger MW, et al. Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels. Front Cell Neurosci. 2013;7:91doi: 10.3389/fncel.2013.00091.
Kratzer, S., Mattusch, C., Metzger, M. W., Dedic, N., Noll-Hussong, M., Kafitz, K. W., Eder, M., Deussing, J. M., Holsboer, F., Kochs, E., & Rammes, G. (2013). Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels. Frontiers in cellular neuroscience, 791. https://doi.org/10.3389/fncel.2013.00091
Kratzer, Stephan, et al. "Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels." Frontiers in cellular neuroscience vol. 7 (2013): 91. doi: https://doi.org/10.3389/fncel.2013.00091
Kratzer S, Mattusch C, Metzger MW, Dedic N, Noll-Hussong M, Kafitz KW, Eder M, Deussing JM, Holsboer F, Kochs E, Rammes G. Activation of CRH receptor type 1 expressed on glutamatergic neurons increases excitability of CA1 pyramidal neurons by the modulation of voltage-gated ion channels. Front Cell Neurosci. 2013 Jul 19;7:91. doi: 10.3389/fncel.2013.00091. eCollection 2013. PMID: 23882180; PMCID: PMC3715697.
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Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response.

Frontiers in molecular neuroscience

Turck CW, Guest PC, Maccarrone G, Ising M, Kloiber S, Lucae S, Holsboer F, Martins-de-Souza D.
PMID: 28912679
Front Mol Neurosci. 2017 Aug 31;10:272. doi: 10.3389/fnmol.2017.00272. eCollection 2017.

The current inability of clinical psychiatry to objectively select the most appropriate treatment is a major factor contributing to the severity and clinical burden of major depressive disorder (MDD). Here, we have attempted to identify plasma protein signatures in...

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Turck CW, Guest PC, Maccarrone G, et al. Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response. Front Mol Neurosci. 2017;10:272doi: 10.3389/fnmol.2017.00272.
Turck, C. W., Guest, P. C., Maccarrone, G., Ising, M., Kloiber, S., Lucae, S., Holsboer, F., & Martins-de-Souza, D. (2017). Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response. Frontiers in molecular neuroscience, 10272. https://doi.org/10.3389/fnmol.2017.00272
Turck, Christoph W, et al. "Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response." Frontiers in molecular neuroscience vol. 10 (2017): 272. doi: https://doi.org/10.3389/fnmol.2017.00272
Turck CW, Guest PC, Maccarrone G, Ising M, Kloiber S, Lucae S, Holsboer F, Martins-de-Souza D. Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response. Front Mol Neurosci. 2017 Aug 31;10:272. doi: 10.3389/fnmol.2017.00272. eCollection 2017. PMID: 28912679; PMCID: PMC5583163.
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Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs.

Scientific reports

Vater M, Möckl L, Gormanns V, Fademrecht CS, Mallmann AM, Ziegart-Sadowska K, Zaba M, Frevert ML, Bräuchle C, Holsboer F, Rein T, Schmidt U, Kirmeier T.
PMID: 28382963
Sci Rep. 2017 Apr 06;7:46011. doi: 10.1038/srep46011.

No abstract available.

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Vater M, Möckl L, Gormanns V, et al. Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs. Sci Rep. 2017;7:46011doi: 10.1038/srep46011.
Vater, M., Möckl, L., Gormanns, V., Fademrecht, C. S., Mallmann, A. M., Ziegart-Sadowska, K., Zaba, M., Frevert, M. L., Bräuchle, C., Holsboer, F., Rein, T., Schmidt, U., & Kirmeier, T. (2017). Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs. Scientific reports, 746011. https://doi.org/10.1038/srep46011
Vater, Magdalena, et al. "Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs." Scientific reports vol. 7 (2017): 46011. doi: https://doi.org/10.1038/srep46011
Vater M, Möckl L, Gormanns V, Fademrecht CS, Mallmann AM, Ziegart-Sadowska K, Zaba M, Frevert ML, Bräuchle C, Holsboer F, Rein T, Schmidt U, Kirmeier T. Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs. Sci Rep. 2017 Apr 06;7:46011. doi: 10.1038/srep46011. PMID: 28382963; PMCID: PMC5382531.
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Depression and cognitive impairment in the elderly: a multicentre study.

European psychiatry : the journal of the Association of European Psychiatrists

Kielholz P, Adams C, Bech P, Bocksberger J, Crombecque A, de Girolamo G, Fayolle K, Holsboer E, Katschnig H, Korten A, Küng A, Meyer J, Pöldinger W, Prilipko L, Reubi I, Sartorius N.
PMID: 19698317
Eur Psychiatry. 1995;10(2):61-74. doi: 10.1016/0924-9338(96)80316-6.

The present study, conducted in collaboration between the Departments of Psychiatry in Swiss Universities and the World Health Organization, had two main goals: to develop assessment methods which could subsequently be used in the Swiss centres in a standard...

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Kielholz P, Adams C, Bech P, et al. Depression and cognitive impairment in the elderly: a multicentre study. Eur Psychiatry. 1995;10(2):61-74doi: 10.1016/0924-9338(96)80316-6.
Kielholz, P., Adams, C., Bech, P., Bocksberger, J., Crombecque, A., de Girolamo, G., Fayolle, K., Holsboer, E., Katschnig, H., Korten, A., Küng, A., Meyer, J., Pöldinger, W., Prilipko, L., Reubi, I., & Sartorius, N. (1995). Depression and cognitive impairment in the elderly: a multicentre study. European psychiatry : the journal of the Association of European Psychiatrists, 10(2), 61-74. https://doi.org/10.1016/0924-9338(96)80316-6
Kielholz, P, et al. "Depression and cognitive impairment in the elderly: a multicentre study." European psychiatry : the journal of the Association of European Psychiatrists vol. 10,2 (1995): 61-74. doi: https://doi.org/10.1016/0924-9338(96)80316-6
Kielholz P, Adams C, Bech P, Bocksberger J, Crombecque A, de Girolamo G, Fayolle K, Holsboer E, Katschnig H, Korten A, Küng A, Meyer J, Pöldinger W, Prilipko L, Reubi I, Sartorius N. Depression and cognitive impairment in the elderly: a multicentre study. Eur Psychiatry. 1995;10(2):61-74. doi: 10.1016/0924-9338(96)80316-6. PMID: 19698317.
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Showing 1 to 12 of 16 entries