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A population-based study of the stratum corneum moisture.

Clinical, cosmetic and investigational dermatology

de Farias Pires T, Azambuja AP, Horimoto AR, Nakamura MS, de Oliveira Alvim R, Krieger JE, Pereira AC.
PMID: 27143945
Clin Cosmet Investig Dermatol. 2016 Apr 18;9:79-87. doi: 10.2147/CCID.S88485. eCollection 2016.

BACKGROUND: The stratum corneum (SC) has important functions as a bound-water modulator and a primary barrier of the human skin from the external environment. However, no large epidemiological study has quantified the relative importance of different exposures with regard...

Cite
de Farias Pires T, Azambuja AP, Horimoto AR, et al. A population-based study of the stratum corneum moisture. Clin Cosmet Investig Dermatol. 2016;9:79-87doi: 10.2147/CCID.S88485.
de Farias Pires, T., Azambuja, A. P., Horimoto, A. R., Nakamura, M. S., de Oliveira Alvim, R., Krieger, J. E., & Pereira, A. C. (2016). A population-based study of the stratum corneum moisture. Clinical, cosmetic and investigational dermatology, 979-87. https://doi.org/10.2147/CCID.S88485
de Farias Pires, Thiago, et al. "A population-based study of the stratum corneum moisture." Clinical, cosmetic and investigational dermatology vol. 9 (2016): 79-87. doi: https://doi.org/10.2147/CCID.S88485
de Farias Pires T, Azambuja AP, Horimoto AR, Nakamura MS, de Oliveira Alvim R, Krieger JE, Pereira AC. A population-based study of the stratum corneum moisture. Clin Cosmet Investig Dermatol. 2016 Apr 18;9:79-87. doi: 10.2147/CCID.S88485. eCollection 2016. PMID: 27143945; PMCID: PMC4845893.
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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.

Molecular psychiatry

Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D.
PMID: 33859359
Mol Psychiatry. 2021 Nov;26(11):6293-6304. doi: 10.1038/s41380-021-01087-0. Epub 2021 Apr 15.

Long and short sleep duration are associated with elevated blood pressure (BP), possibly through effects on molecular pathways that influence neuroendocrine and vascular systems. To gain new insights into the genetic basis of sleep-related BP variation, we performed genome-wide...

Cite
Wang H, Noordam R, Cade BE, et al. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021;26(11):6293-6304doi: 10.1038/s41380-021-01087-0.
Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y., Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L. P., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X. O., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C. T., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S., & van Heemst, D. (2021). Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Molecular psychiatry, 26(11), 6293-6304. https://doi.org/10.1038/s41380-021-01087-0
Wang, Heming, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Molecular psychiatry vol. 26,11 (2021): 6293-6304. doi: https://doi.org/10.1038/s41380-021-01087-0
Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021 Nov;26(11):6293-6304. doi: 10.1038/s41380-021-01087-0. Epub 2021 Apr 15. PMID: 33859359; PMCID: PMC8517040.
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Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.

Molecular psychiatry

Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D.
PMID: 33859359
Mol Psychiatry. 2021 Nov;26(11):6293-6304. doi: 10.1038/s41380-021-01087-0. Epub 2021 Apr 15.

Long and short sleep duration are associated with elevated blood pressure (BP), possibly through effects on molecular pathways that influence neuroendocrine and vascular systems. To gain new insights into the genetic basis of sleep-related BP variation, we performed genome-wide...

Cite
Wang H, Noordam R, Cade BE, et al. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021;26(11):6293-6304doi: 10.1038/s41380-021-01087-0.
Wang, H., Noordam, R., Cade, B. E., Schwander, K., Winkler, T. W., Lee, J., Sung, Y. J., Bentley, A. R., Manning, A. K., Aschard, H., Kilpeläinen, T. O., Ilkov, M., Brown, M. R., Horimoto, A. R., Richard, M., Bartz, T. M., Vojinovic, D., Lim, E., Nierenberg, J. L., Liu, Y., Chitrala, K., Rankinen, T., Musani, S. K., Franceschini, N., Rauramaa, R., Alver, M., Zee, P. C., Harris, S. E., van der Most, P. J., Nolte, I. M., Munroe, P. B., Palmer, N. D., Kühnel, B., Weiss, S., Wen, W., Hall, K. A., Lyytikäinen, L. P., O'Connell, J., Eiriksdottir, G., Launer, L. J., de Vries, P. S., Arking, D. E., Chen, H., Boerwinkle, E., Krieger, J. E., Schreiner, P. J., Sidney, S., Shikany, J. M., Rice, K., Chen, Y. I., Gharib, S. A., Bis, J. C., Luik, A. I., Ikram, M. A., Uitterlinden, A. G., Amin, N., Xu, H., Levy, D., He, J., Lohman, K. K., Zonderman, A. B., Rice, T. K., Sims, M., Wilson, G., Sofer, T., Rich, S. S., Palmas, W., Yao, J., Guo, X., Rotter, J. I., Biermasz, N. R., Mook-Kanamori, D. O., Martin, L. W., Barac, A., Wallace, R. B., Gottlieb, D. J., Komulainen, P., Heikkinen, S., Mägi, R., Milani, L., Metspalu, A., Starr, J. M., Milaneschi, Y., Waken, R. J., Gao, C., Waldenberger, M., Peters, A., Strauch, K., Meitinger, T., Roenneberg, T., Völker, U., Dörr, M., Shu, X. O., Mukherjee, S., Hillman, D. R., Kähönen, M., Wagenknecht, L. E., Gieger, C., Grabe, H. J., Zheng, W., Palmer, L. J., Lehtimäki, T., Gudnason, V., Morrison, A. C., Pereira, A. C., Fornage, M., Psaty, B. M., van Duijn, C. M., Liu, C. T., Kelly, T. N., Evans, M. K., Bouchard, C., Fox, E. R., Kooperberg, C., Zhu, X., Lakka, T. A., Esko, T., North, K. E., Deary, I. J., Snieder, H., Penninx, B. W. J. H., Gauderman, W. J., Rao, D. C., Redline, S., & van Heemst, D. (2021). Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Molecular psychiatry, 26(11), 6293-6304. https://doi.org/10.1038/s41380-021-01087-0
Wang, Heming, et al. "Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure." Molecular psychiatry vol. 26,11 (2021): 6293-6304. doi: https://doi.org/10.1038/s41380-021-01087-0
Wang H, Noordam R, Cade BE, Schwander K, Winkler TW, Lee J, Sung YJ, Bentley AR, Manning AK, Aschard H, Kilpeläinen TO, Ilkov M, Brown MR, Horimoto AR, Richard M, Bartz TM, Vojinovic D, Lim E, Nierenberg JL, Liu Y, Chitrala K, Rankinen T, Musani SK, Franceschini N, Rauramaa R, Alver M, Zee PC, Harris SE, van der Most PJ, Nolte IM, Munroe PB, Palmer ND, Kühnel B, Weiss S, Wen W, Hall KA, Lyytikäinen LP, O'Connell J, Eiriksdottir G, Launer LJ, de Vries PS, Arking DE, Chen H, Boerwinkle E, Krieger JE, Schreiner PJ, Sidney S, Shikany JM, Rice K, Chen YI, Gharib SA, Bis JC, Luik AI, Ikram MA, Uitterlinden AG, Amin N, Xu H, Levy D, He J, Lohman KK, Zonderman AB, Rice TK, Sims M, Wilson G, Sofer T, Rich SS, Palmas W, Yao J, Guo X, Rotter JI, Biermasz NR, Mook-Kanamori DO, Martin LW, Barac A, Wallace RB, Gottlieb DJ, Komulainen P, Heikkinen S, Mägi R, Milani L, Metspalu A, Starr JM, Milaneschi Y, Waken RJ, Gao C, Waldenberger M, Peters A, Strauch K, Meitinger T, Roenneberg T, Völker U, Dörr M, Shu XO, Mukherjee S, Hillman DR, Kähönen M, Wagenknecht LE, Gieger C, Grabe HJ, Zheng W, Palmer LJ, Lehtimäki T, Gudnason V, Morrison AC, Pereira AC, Fornage M, Psaty BM, van Duijn CM, Liu CT, Kelly TN, Evans MK, Bouchard C, Fox ER, Kooperberg C, Zhu X, Lakka TA, Esko T, North KE, Deary IJ, Snieder H, Penninx BWJH, Gauderman WJ, Rao DC, Redline S, van Heemst D. Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure. Mol Psychiatry. 2021 Nov;26(11):6293-6304. doi: 10.1038/s41380-021-01087-0. Epub 2021 Apr 15. PMID: 33859359; PMCID: PMC8517040.
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante.

Diabetes & metabolic syndrome

Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS.
PMID: 34920192
Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03.

BACKGROUND AND AIMS: Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different populations. Here, in an indigenous population-based study, we examined whether FTO rs9939609...

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Leite LCG, Dos Santos MC, Duarte NE, et al. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021;16(1):102358doi: 10.1016/j.dsx.2021.102358.
Leite, L. C. G., Dos Santos, M. C., Duarte, N. E., Horimoto, A. R. V. R., Crispim, F., Vieira Filho, J. P. B., Dal Fabbro, A. L., Franco, L. J., & Moises, R. S. (2021). Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes & metabolic syndrome, 16(1), 102358. https://doi.org/10.1016/j.dsx.2021.102358
Leite, Lanna C G, et al. "Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante." Diabetes & metabolic syndrome vol. 16,1 (2021): 102358. doi: https://doi.org/10.1016/j.dsx.2021.102358
Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03. PMID: 34920192.
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Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits.

HGG advances

Sun D, Richard M, Musani SK, Sung YJ, Winkler TW, Schwander K, Chai JF, Guo X, Kilpeläinen TO, Vojinovic D, Aschard H, Bartz TM, Bielak LF, Brown MR, Chitrala K, Hartwig FP, Horimoto ARVR, Liu Y, Manning AK, Noordam R, Smith AV, Harris SE, Kühnel B, Lyytikäinen LP, Nolte IM, Rauramaa R, van der Most PJ, Wang R, Ware EB, Weiss S, Wen W, Yanek LR, Arking DE, Arnett DK, Barac A, Boerwinkle E, Broeckel U, Chakravarti A, Chen YI, Cupples LA, Davigulus ML, de Las Fuentes L, de Mutsert R, de Vries PS, Delaney JAC, Roux AVD, Dörr M, Faul JD, Fretts AM, Gallo LC, Grabe HJ, Gu CC, Harris TB, Hartman CCA, Heikkinen S, Ikram MA, Isasi C, Johnson WC, Jonas JB, Kaplan RC, Komulainen P, Krieger JE, Levy D, Liu J, Lohman K, Luik AI, Martin LW, Meitinger T, Milaneschi Y, O'Connell JR, Palmas WR, Peters A, Peyser PA, Pulkki-Råback L, Raffel LJ, Reiner AP, Rice K, Robinson JG, Rosendaal FR, Schmidt CO, Schreiner PJ, Schwettmann L, Shikany JM, Shu XO, Sidney S, Sims M, Smith JA, Sotoodehnia N, Strauch K, Tai ES, Taylor K, Uitterlinden AG, van Duijn CM, Waldenberger M, Wee HL, Wei WB, Wilson G, Xuan D, Yao J, Zeng D, Zhao W, Zhu X, Zonderman AB, Becker DM, Deary IJ, Gieger C, Lakka TA, Lehtimäki T, North KE, Oldehinkel AJ, Penninx BWJH, Snieder H, Wang YX, Weir DR, Zheng W, Evans MK, Gauderman WJ, Gudnason V, Horta BL, Liu CT, Mook-Kanamori DO, Morrison AC, Pereira AC, Psaty BM, Amin N, Fox ER, Kooperberg C, Sim X, Bierut L, Rotter JI, Kardia SLR, Franceschini N, Rao DC, Fornage M.
PMID: 34734193
HGG Adv. 2021 Jan 14;2(1). doi: 10.1016/j.xhgg.2020.100013. Epub 2020 Oct 31.

Psychological and social factors are known to influence blood pressure (BP) and risk of hypertension and associated cardiovascular diseases. To identify novel BP loci, we carried out genome-wide association meta-analyses of systolic, diastolic, pulse, and mean arterial BP taking...

Cite
Sun D, Richard M, Musani SK, et al. Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. HGG Adv. 2020;2(1)doi: 10.1016/j.xhgg.2020.100013.
Sun, D., Richard, M., Musani, S. K., Sung, Y. J., Winkler, T. W., Schwander, K., Chai, J. F., Guo, X., Kilpeläinen, T. O., Vojinovic, D., Aschard, H., Bartz, T. M., Bielak, L. F., Brown, M. R., Chitrala, K., Hartwig, F. P., Horimoto, A. R. V. R., Liu, Y., Manning, A. K., Noordam, R., Smith, A. V., Harris, S. E., Kühnel, B., Lyytikäinen, L. P., Nolte, I. M., Rauramaa, R., van der Most, P. J., Wang, R., Ware, E. B., Weiss, S., Wen, W., Yanek, L. R., Arking, D. E., Arnett, D. K., Barac, A., Boerwinkle, E., Broeckel, U., Chakravarti, A., Chen, Y. I., Cupples, L. A., Davigulus, M. L., de Las Fuentes, L., de Mutsert, R., de Vries, P. S., Delaney, J. A. C., Roux, A. V. D., Dörr, M., Faul, J. D., Fretts, A. M., Gallo, L. C., Grabe, H. J., Gu, C. C., Harris, T. B., Hartman, C. C. A., Heikkinen, S., Ikram, M. A., Isasi, C., Johnson, W. C., Jonas, J. B., Kaplan, R. C., Komulainen, P., Krieger, J. E., Levy, D., Liu, J., Lohman, K., Luik, A. I., Martin, L. W., Meitinger, T., Milaneschi, Y., O'Connell, J. R., Palmas, W. R., Peters, A., Peyser, P. A., Pulkki-Råback, L., Raffel, L. J., Reiner, A. P., Rice, K., Robinson, J. G., Rosendaal, F. R., Schmidt, C. O., Schreiner, P. J., Schwettmann, L., Shikany, J. M., Shu, X. O., Sidney, S., Sims, M., Smith, J. A., Sotoodehnia, N., Strauch, K., Tai, E. S., Taylor, K., Uitterlinden, A. G., van Duijn, C. M., Waldenberger, M., Wee, H. L., Wei, W. B., Wilson, G., Xuan, D., Yao, J., Zeng, D., Zhao, W., Zhu, X., Zonderman, A. B., Becker, D. M., Deary, I. J., Gieger, C., Lakka, T. A., Lehtimäki, T., North, K. E., Oldehinkel, A. J., Penninx, B. W. J. H., Snieder, H., Wang, Y. X., Weir, D. R., Zheng, W., Evans, M. K., Gauderman, W. J., Gudnason, V., Horta, B. L., Liu, C. T., Mook-Kanamori, D. O., Morrison, A. C., Pereira, A. C., Psaty, B. M., Amin, N., Fox, E. R., Kooperberg, C., Sim, X., Bierut, L., Rotter, J. I., Kardia, S. L. R., Franceschini, N., Rao, D. C., & Fornage, M. (2021). Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. HGG advances, 2(1), . https://doi.org/10.1016/j.xhgg.2020.100013
Sun, Daokun, et al. "Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits." HGG advances vol. 2,1 (2021). doi: https://doi.org/10.1016/j.xhgg.2020.100013
Sun D, Richard M, Musani SK, Sung YJ, Winkler TW, Schwander K, Chai JF, Guo X, Kilpeläinen TO, Vojinovic D, Aschard H, Bartz TM, Bielak LF, Brown MR, Chitrala K, Hartwig FP, Horimoto ARVR, Liu Y, Manning AK, Noordam R, Smith AV, Harris SE, Kühnel B, Lyytikäinen LP, Nolte IM, Rauramaa R, van der Most PJ, Wang R, Ware EB, Weiss S, Wen W, Yanek LR, Arking DE, Arnett DK, Barac A, Boerwinkle E, Broeckel U, Chakravarti A, Chen YI, Cupples LA, Davigulus ML, de Las Fuentes L, de Mutsert R, de Vries PS, Delaney JAC, Roux AVD, Dörr M, Faul JD, Fretts AM, Gallo LC, Grabe HJ, Gu CC, Harris TB, Hartman CCA, Heikkinen S, Ikram MA, Isasi C, Johnson WC, Jonas JB, Kaplan RC, Komulainen P, Krieger JE, Levy D, Liu J, Lohman K, Luik AI, Martin LW, Meitinger T, Milaneschi Y, O'Connell JR, Palmas WR, Peters A, Peyser PA, Pulkki-Råback L, Raffel LJ, Reiner AP, Rice K, Robinson JG, Rosendaal FR, Schmidt CO, Schreiner PJ, Schwettmann L, Shikany JM, Shu XO, Sidney S, Sims M, Smith JA, Sotoodehnia N, Strauch K, Tai ES, Taylor K, Uitterlinden AG, van Duijn CM, Waldenberger M, Wee HL, Wei WB, Wilson G, Xuan D, Yao J, Zeng D, Zhao W, Zhu X, Zonderman AB, Becker DM, Deary IJ, Gieger C, Lakka TA, Lehtimäki T, North KE, Oldehinkel AJ, Penninx BWJH, Snieder H, Wang YX, Weir DR, Zheng W, Evans MK, Gauderman WJ, Gudnason V, Horta BL, Liu CT, Mook-Kanamori DO, Morrison AC, Pereira AC, Psaty BM, Amin N, Fox ER, Kooperberg C, Sim X, Bierut L, Rotter JI, Kardia SLR, Franceschini N, Rao DC, Fornage M. Multi-Ancestry Genome-wide Association Study Accounting for Gene-Psychosocial Factor Interactions Identifies Novel Loci for Blood Pressure Traits. HGG Adv. 2021 Jan 14;2(1). doi: 10.1016/j.xhgg.2020.100013. Epub 2020 Oct 31. PMID: 34734193; PMCID: PMC8562625.
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Genomic ancestry as a predictor of haemodynamic profile in heart failure.

Open heart

Bernardez-Pereira S, Gioli-Pereira L, Marcondes-Braga FG, Santos PC, Spina JM, Horimoto AR, Santos HC, Bacal F, Fernandes F, Mansur AJ, Pietrobon R, Krieger JE, Mesquita ET, Pereira AC.
PMID: 27547430
Open Heart. 2016 Jul 26;3(2):e000434. doi: 10.1136/openhrt-2016-000434. eCollection 2016.

OBJECTIVE: The aim of this study is to assess the association between genetic ancestry, self-declared race and haemodynamic parameters in patients with chronic heart failure (HF).METHODS: Observational, cross-sectional study. Eligible participants were aged between 18 and 80 years; ejection...

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Bernardez-Pereira S, Gioli-Pereira L, Marcondes-Braga FG, et al. Genomic ancestry as a predictor of haemodynamic profile in heart failure. Open Heart. 2016;3(2):e000434doi: 10.1136/openhrt-2016-000434.
Bernardez-Pereira, S., Gioli-Pereira, L., Marcondes-Braga, F. G., Santos, P. C., Spina, J. M., Horimoto, A. R., Santos, H. C., Bacal, F., Fernandes, F., Mansur, A. J., Pietrobon, R., Krieger, J. E., Mesquita, E. T., & Pereira, A. C. (2016). Genomic ancestry as a predictor of haemodynamic profile in heart failure. Open heart, 3(2), e000434. https://doi.org/10.1136/openhrt-2016-000434
Bernardez-Pereira, Sabrina, et al. "Genomic ancestry as a predictor of haemodynamic profile in heart failure." Open heart vol. 3,2 (2016): e000434. doi: https://doi.org/10.1136/openhrt-2016-000434
Bernardez-Pereira S, Gioli-Pereira L, Marcondes-Braga FG, Santos PC, Spina JM, Horimoto AR, Santos HC, Bacal F, Fernandes F, Mansur AJ, Pietrobon R, Krieger JE, Mesquita ET, Pereira AC. Genomic ancestry as a predictor of haemodynamic profile in heart failure. Open Heart. 2016 Jul 26;3(2):e000434. doi: 10.1136/openhrt-2016-000434. eCollection 2016. PMID: 27547430; PMCID: PMC4975862.
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Penetrance rate estimation in autosomal dominant conditions.

Genetics and molecular biology

Otto PA, Horimoto AR.
PMID: 23055795
Genet Mol Biol. 2012 Jul;35(3):583-8. doi: 10.1590/S1415-47572012005000051. Epub 2012 Aug 02.

Accurate estimates of the penetrance rate of autosomal dominant conditions are important, among other issues, for optimizing recurrence risks in genetic counseling. The present work on penetrance rate estimation from pedigree data considers the following situations: 1) estimation of...

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Otto PA, Horimoto AR. Penetrance rate estimation in autosomal dominant conditions. Genet Mol Biol. 2012;35(3):583-8doi: 10.1590/S1415-47572012005000051.
Otto, P. A., & Horimoto, A. R. (2012). Penetrance rate estimation in autosomal dominant conditions. Genetics and molecular biology, 35(3), 583-8. https://doi.org/10.1590/S1415-47572012005000051
Otto, Paulo A, and Horimoto, Andréa R V R. "Penetrance rate estimation in autosomal dominant conditions." Genetics and molecular biology vol. 35,3 (2012): 583-8. doi: https://doi.org/10.1590/S1415-47572012005000051
Otto PA, Horimoto AR. Penetrance rate estimation in autosomal dominant conditions. Genet Mol Biol. 2012 Jul;35(3):583-8. doi: 10.1590/S1415-47572012005000051. Epub 2012 Aug 02. PMID: 23055795; PMCID: PMC3459406.
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante.

Diabetes & metabolic syndrome

Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS.
PMID: 34920192
Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03.

BACKGROUND AND AIMS: Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different populations. Here, in an indigenous population-based study, we examined whether FTO rs9939609...

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Leite LCG, Dos Santos MC, Duarte NE, et al. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021;16(1):102358doi: 10.1016/j.dsx.2021.102358.
Leite, L. C. G., Dos Santos, M. C., Duarte, N. E., Horimoto, A. R. V. R., Crispim, F., Vieira Filho, J. P. B., Dal Fabbro, A. L., Franco, L. J., & Moises, R. S. (2021). Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes & metabolic syndrome, 16(1), 102358. https://doi.org/10.1016/j.dsx.2021.102358
Leite, Lanna C G, et al. "Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante." Diabetes & metabolic syndrome vol. 16,1 (2021): 102358. doi: https://doi.org/10.1016/j.dsx.2021.102358
Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03. PMID: 34920192.
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante.

Diabetes & metabolic syndrome

Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS.
PMID: 34920192
Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03.

BACKGROUND AND AIMS: Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different populations. Here, in an indigenous population-based study, we examined whether FTO rs9939609...

Cite
Leite LCG, Dos Santos MC, Duarte NE, et al. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021;16(1):102358doi: 10.1016/j.dsx.2021.102358.
Leite, L. C. G., Dos Santos, M. C., Duarte, N. E., Horimoto, A. R. V. R., Crispim, F., Vieira Filho, J. P. B., Dal Fabbro, A. L., Franco, L. J., & Moises, R. S. (2021). Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes & metabolic syndrome, 16(1), 102358. https://doi.org/10.1016/j.dsx.2021.102358
Leite, Lanna C G, et al. "Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante." Diabetes & metabolic syndrome vol. 16,1 (2021): 102358. doi: https://doi.org/10.1016/j.dsx.2021.102358
Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03. PMID: 34920192.
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante.

Diabetes & metabolic syndrome

Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS.
PMID: 34920192
Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03.

BACKGROUND AND AIMS: Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different populations. Here, in an indigenous population-based study, we examined whether FTO rs9939609...

Cite
Leite LCG, Dos Santos MC, Duarte NE, et al. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021;16(1):102358doi: 10.1016/j.dsx.2021.102358.
Leite, L. C. G., Dos Santos, M. C., Duarte, N. E., Horimoto, A. R. V. R., Crispim, F., Vieira Filho, J. P. B., Dal Fabbro, A. L., Franco, L. J., & Moises, R. S. (2021). Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes & metabolic syndrome, 16(1), 102358. https://doi.org/10.1016/j.dsx.2021.102358
Leite, Lanna C G, et al. "Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante." Diabetes & metabolic syndrome vol. 16,1 (2021): 102358. doi: https://doi.org/10.1016/j.dsx.2021.102358
Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03. PMID: 34920192.
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Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States.

Journal of the American Society of Nephrology : JASN

Horimoto ARVR, Xue D, Cai J, Lash JP, Daviglus ML, Franceschini N, Thornton TA.
PMID: 34670813
J Am Soc Nephrol. 2021 Oct 20; doi: 10.1681/ASN.2021050617. Epub 2021 Oct 20.

BACKGROUND: Admixture mapping is a powerful approach for gene mapping of complex traits that leverages the diverse genetic ancestry in populations with recent admixture, such as Hispanic or Latino individuals in the United States. These individuals have an increased...

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Horimoto ARVR, Xue D, Cai J, et al. Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. J Am Soc Nephrol. 2021;doi: 10.1681/ASN.2021050617.
Horimoto, A. R. V. R., Xue, D., Cai, J., Lash, J. P., Daviglus, M. L., Franceschini, N., & Thornton, T. A. (2021). Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. Journal of the American Society of Nephrology : JASN, . https://doi.org/10.1681/ASN.2021050617
Horimoto, Andrea R V R, et al. "Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States." Journal of the American Society of Nephrology : JASN vol. (2021). doi: https://doi.org/10.1681/ASN.2021050617
Horimoto ARVR, Xue D, Cai J, Lash JP, Daviglus ML, Franceschini N, Thornton TA. Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identifies European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. J Am Soc Nephrol. 2021 Oct 20; doi: 10.1681/ASN.2021050617. Epub 2021 Oct 20. PMID: 34670813.
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Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante.

Diabetes & metabolic syndrome

Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS.
PMID: 34920192
Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03.

BACKGROUND AND AIMS: Common variants in fat mass and obesity-associated (FTO) gene have been implicated as a susceptibility locus for obesity and type 2 diabetes in different populations. Here, in an indigenous population-based study, we examined whether FTO rs9939609...

Cite
Leite LCG, Dos Santos MC, Duarte NE, et al. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021;16(1):102358doi: 10.1016/j.dsx.2021.102358.
Leite, L. C. G., Dos Santos, M. C., Duarte, N. E., Horimoto, A. R. V. R., Crispim, F., Vieira Filho, J. P. B., Dal Fabbro, A. L., Franco, L. J., & Moises, R. S. (2021). Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes & metabolic syndrome, 16(1), 102358. https://doi.org/10.1016/j.dsx.2021.102358
Leite, Lanna C G, et al. "Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante." Diabetes & metabolic syndrome vol. 16,1 (2021): 102358. doi: https://doi.org/10.1016/j.dsx.2021.102358
Leite LCG, Dos Santos MC, Duarte NE, Horimoto ARVR, Crispim F, Vieira Filho JPB, Dal Fabbro AL, Franco LJ, Moises RS. Association of fat mass and obesity-associated (FTO) gene rs9939609 with obesity-related traits and glucose intolerance in an indigenous population, the Xavante. Diabetes Metab Syndr. 2021 Dec 03;16(1):102358. doi: 10.1016/j.dsx.2021.102358. Epub 2021 Dec 03. PMID: 34920192.
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