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Showing 1 to 4 of 4 entries
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Can telomere shortening be the main indicator of non-viable fetus elimination?.

Molecular cytogenetics

Huleyuk N, Tkach I, Zastavna D, Tyrka M.
PMID: 29416566
Mol Cytogenet. 2018 Jan 25;11:11. doi: 10.1186/s13039-018-0361-9. eCollection 2018.

BACKGROUND: Telomeres are transcriptionally inactive genomic areas, which, if shortened, are associated with pathological processes, unsuccessful fertilization, aging, and death. Telomere dysfunction has also been linked to chromosomal rearrangements and genomic instability. The role of telomeres in postnatal life...

Temozolomide promotes genomic and phenotypic changes in glioblastoma cells.

Cancer cell international

Stepanenko AA, Andreieva SV, Korets KV, Mykytenko DO, Baklaushev VP, Huleyuk NL, Kovalova OA, Kotsarenko KV, Chekhonin VP, Vassetzky YS, Avdieiev SS, Dmitrenko VV.
PMID: 27158244
Cancer Cell Int. 2016 May 05;16:36. doi: 10.1186/s12935-016-0311-8. eCollection 2016.

BACKGROUND: Temozolomide (TMZ) is a first-line drug for the treatment of glioblastoma. Long-term TMZ-treated tumour cells acquire TMZ resistance by profound reprogramming of the transcriptome, proteome, kinome, metabolism, and demonstrate versatile and opposite changes in proliferation, invasion, in vivo...

Cytogenetic and molecular analyses of de novo translocation dic(9;13)(p11.2;p12) in an infertile male.

Molecular cytogenetics

Wiland E, Olszewska M, Georgiadis A, Huleyuk N, Panasiuk B, Zastavna D, Yatsenko SA, Jedrzejczak P, Midro AT, Yatsenko AN, Kurpisz M.
PMID: 24559467
Mol Cytogenet. 2014 Feb 21;7(1):14. doi: 10.1186/1755-8166-7-14.

BACKGROUND: Whole arm t(9;13)(p11;p12) translocations are rare and have been described only a few times; all of the previously reported cases were familial.RESULTS: We present here an infertile male carrier with a whole-arm reciprocal translocation dic(9;13)(p11.2;p12) revealed by GTG-,...

Comparison of rapid solvent extraction systems for the GC-MS/MS characterization of polycyclic aromatic hydrocarbons in aged, contaminated soil.

MethodsX

Haleyur N, Shahsavari E, Mansur AA, Koshlaf E, Morrison PD, Osborn AM, Ball AS.
PMID: 27200269
MethodsX. 2016 Apr 26;3:364-70. doi: 10.1016/j.mex.2016.04.007. eCollection 2016.

Polycyclic aromatic hydrocarbons (PAHs) are a major class of organic hydrocarbons with high molecular weight that originate from both natural and anthropogenic sources. Sixteen PAHs are included in the U.S Environmental Protection agency list of priority pollutants due to...

Showing 1 to 4 of 4 entries