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Showing 1 to 12 of 39 entries
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MuseumFinland—Finnish museums on the semantic web

museums

Hyvönen E, Mäkelä E.
GSID: jAyIhVANHd8J
E Hyvönen, E Mäkelä, M Salminen, A Valo… - Journal of Web …, 2005 - Elsevier

This article presents the semantic portal MuseumFinland for publishing heterogeneous museum collections on the Semantic Web. It is shown how museums with their semantically rich and interrelated collection content can create a large, consolidated semantic collection portal …

Vitamin D and adipose tissue-more than storage.

Frontiers in physiology

Mutt SJ, Hyppönen E, Saarnio J, Järvelin MR, Herzig KH.
PMID: 25009502
Front Physiol. 2014 Jun 24;5:228. doi: 10.3389/fphys.2014.00228. eCollection 2014.

The pandemic increase in obesity is inversely associated with vitamin D levels. While a higher BMI was causally related to lower 25-hydroxyvitamin D (25(OH)D), no evidence was obtained for a BMI lowering effect by higher 25(OH)D. Some of the...

Mechanisms of Tenebrescence and Persistent Luminescence in Synthetic Hackmanite Na8Al6Si6O24(Cl,S)2.

ACS applied materials & interfaces

Norrbo I, Gluchowski P, Hyppänen I, Laihinen T, Laukkanen P, Mäkelä J, Mamedov F, Santos HS, Sinkkonen J, Tuomisto M, Viinikanoja A, Lastusaari M.
PMID: 27088662
ACS Appl Mater Interfaces. 2016 May 11;8(18):11592-602. doi: 10.1021/acsami.6b01959. Epub 2016 May 02.

Synthetic hackmanites, Na8Al6Si6O24(Cl,S)2, showing efficient purple tenebrescence and blue/white persistent luminescence were studied using different spectroscopic techniques to obtain a quantified view on the storage and release of optical energy in these materials. The persistent luminescence emitter was identified...

Automatic assessment of the myoclonus severity from videos recorded according to standardized Unified Myoclonus Rating Scale protocol and using human pose and body movement analysis.

Seizure

Hyppönen J, Hakala A, Annala K, Zhang H, Peltola J, Mervaala E, Kälviäinen R.
PMID: 32035366
Seizure. 2020 Jan 24;76:72-78. doi: 10.1016/j.seizure.2020.01.014. Epub 2020 Jan 24.

PURPOSE: Myoclonus in progressive myoclonus epilepsy type 1 (EPM1) patients shows marked variability, which presents a substantial challenge in devising treatment and conducting clinical trials. Consequently, fast and objective myoclonus quantification methods are needed.METHODS: Ten video-recorded unified myoclonus rating...

Unlocking the causal link of metabolically different adiposity subtypes with brain volumes and the risks of dementia and stroke: A Mendelian randomization study.

Neurobiology of aging

Mulugeta A, Lumsden A, Hyppönen E.
PMID: 33770530
Neurobiol Aging. 2021 Jun;102:161-169. doi: 10.1016/j.neurobiolaging.2021.02.010. Epub 2021 Feb 21.

To establish causal evidence for the association of adiposity-related metabolic abnormalities with brain volumes, and the risks of dementia and stroke, we applied 1- and 2-sample Mendelian randomization (MR) analyses using up to 336,309 UK Biobank participants. We used...

Comparison between Fluorescence Imaging and Elemental Analysis to Determine Biodistribution of Inorganic Nanoparticles with Strong Light Absorption.

ACS applied materials & interfaces

Tamarov K, Wang JT, Kari J, Happonen E, Vesavaara I, Niemelä M, Perämäki P, Al-Jamal KT, Xu W, Lehto VP.
PMID: 34405988
ACS Appl Mater Interfaces. 2021 Sep 01;13(34):40392-40400. doi: 10.1021/acsami.1c11875. Epub 2021 Aug 16.

Black porous silicon nanoparticles (BPSi NPs) are known as highly efficient infrared light absorbers that are well-suitable for photothermal therapy (PTT) and photoacoustic imaging (PAI). PTT and PAI require a sufficient number of effectively light-absorbing NPs to be accumulated...

High coffee consumption, brain volume and risk of dementia and stroke.

Nutritional neuroscience

Pham K, Mulugeta A, Zhou A, O'Brien JT, Llewellyn DJ, Hyppönen E.
PMID: 34165394
Nutr Neurosci. 2021 Jun 24;1-12. doi: 10.1080/1028415X.2021.1945858. Epub 2021 Jun 24.

BACKGROUND: Coffee is a highly popular beverage worldwide, containing caffeine which is a central nervous system stimulant.OBJECTIVES: We examined whether habitual coffee consumption is associated with differences in brain volumes or the odds of dementia or stroke.METHODS: We conducted...

Mendelian randomization case-control PheWAS in UK Biobank shows evidence of causality for smoking intensity in 28 distinct clinical conditions.

EClinicalMedicine

King C, Mulugeta A, Nabi F, Walton R, Zhou A, Hyppönen E.
PMID: 33089118
EClinicalMedicine. 2020 Jul 31;26:100488. doi: 10.1016/j.eclinm.2020.100488. eCollection 2020 Sep.

BACKGROUND: Smoking is one of the greatest threats to public health worldwide. We integrated phenome-wide association study (PheWAS) and Mendelian randomization (MR) approaches to explore causal effects of genetically predicted smoking intensity across the human disease spectrum.METHODS: We conducted...

Estimating the influence of body mass index (BMI) on mortality using offspring BMI as an instrumental variable.

International journal of obesity (2005)

Hyppönen E, Carslake D, Berry DJ, Power C, Davey Smith G.
PMID: 34497352
Int J Obes (Lond). 2022 Jan;46(1):77-84. doi: 10.1038/s41366-021-00962-8. Epub 2021 Sep 08.

OBJECTIVE: High body mass index (BMI) is an important predictor of mortality but estimating underlying causality is hampered by confounding and pre-existing disease. Here, we use information from the offspring to approximate parental BMIs, with an aim to avoid...

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.

Nature genetics

Okbay A, Baselmans BM, Neve JE, Turley P, Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Thorleifsson G, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W, Amin N, Bakshi A, Bergmann S, Bjornsdottir G, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner AJ, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Liewald DC, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Råback L, Quaye L, Räikkönen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bültmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hyppönen E, Iacono WG, Järvelin MR, Jöckel KH, Kaprio J, Kardia SL, Keltikangas-Järvinen L, Kraft P, Kubzansky LD, Lehtimäki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sørensen TI, Spector TD, Starr JM, Stefansson K, Steptoe A, Terracciano A, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D.
PMID: 27463399
Nat Genet. 2016 Jul 27;48(8):970. doi: 10.1038/ng0816-970c.

No abstract available.

Usability Factors Associated With Physicians' Distress and Information System-Related Stress: Cross-Sectional Survey.

JMIR medical informatics

Heponiemi T, Kujala S, Vainiomäki S, Vehko T, Lääveri T, Vänskä J, Ketola E, Puttonen S, Hyppönen H.
PMID: 31687938
JMIR Med Inform. 2019 Nov 05;7(4):e13466. doi: 10.2196/13466.

BACKGROUND: Constantly changing and difficult-to-use information systems have arisen as a significant source of stress in physicians' work. Physicians have reported several usability problems, system failures, and a lack of integration between the systems and have experienced that systems...

Quenching of the upconversion luminescence of NaYF₄:Yb³⁺,Er³⁺ and NaYF₄:Yb³⁺,Tm³⁺ nanophosphors by water: the role of the sensitizer Yb³⁺ in non-radiative relaxation.

Nanoscale

Arppe R, Hyppänen I, Perälä N, Peltomaa R, Kaiser M, Würth C, Christ S, Resch-Genger U, Schäferling M, Soukka T.
PMID: 26104183
Nanoscale. 2015 Jul 21;7(27):11746-57. doi: 10.1039/c5nr02100f. Epub 2015 Jun 24.

We have studied the mechanisms of water-based quenching of the upconversion photoluminescence of upconverting nanophosphors (UCNPs) via luminescence decay measurements for a better understanding of the non-radiative deactivation pathways responsible for the relatively low upconversion luminescence efficiency in aqueous...

Showing 1 to 12 of 39 entries