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Showing 1 to 12 of 1105 entries
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Enantioselective Synthesis of Silacyclopentanes.

Angewandte Chemie (International ed. in English)

Igawa K, Yoshihiro D, Abe Y, Tomooka K.
PMID: 27037672
Angew Chem Int Ed Engl. 2016 May 04;55(19):5814-8. doi: 10.1002/anie.201511728. Epub 2016 Apr 01.

A variety of functionalized silacyclopentanes were synthesized by highly enantioselective β-eliminations of silacyclopentene oxides followed by stereospecific transformations. The reaction mechanism of the β-elimination was elucidated by DFT calculations. An in vitro biological assay with an oxy-functionalized silacyclopentane showed...

Cervical sympathectomy affects gonadotropin-releasing hormone, luteinizing hormone and testosterone in male rats.

Journal of anesthesia

Iwama H, Tase C, Tonosaki Y, Sugiura Y.
PMID: 28921287
J Anesth. 1995 Jun;9(2):166-169. doi: 10.1007/BF02479850.

To examine the effects of bilateral cervical sympathectomy on the secretion of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and testosterone (TS), 24 male rats were divided into four groups: control (C), light (L), sympathectomy (S), and light-sympathectomy (LS) groups....

Phosphorylation of p38 in Trigeminal Ganglion Neurons Contributes to Tongue Heat Hypersensitivity in Mice.

Journal of oral & facial pain and headache

Maruno M, Shinoda M, Honda K, Ito R, Urata K, Watanabe M, Okada S, Lee J, Gionhaku N, Iwata K.
PMID: 28973050
J Oral Facial Pain Headache. 2017;31(4):372–380. doi: 10.11607/ofph.1849. Epub 2017 Oct 03.

AIMS: To develop a tongue pain model with no mucosal pathologic changes and to examine whether phosphorylation of p38 in trigeminal ganglion (TG) neurons innervating the tongue is associated with tongue heat hypersensitivity in mice.METHODS: Tongue heat sensitivity in...

Molecular detection and characterization of infectious laryngotracheitis virus (Gallid herpesvirus-1) from clinical samples of commercial poultry flocks in India.

Virusdisease

Gowthaman V, Singh SD, Dhama K, Barathidasan R, Mathapati BS, Srinivasan P, Saravanan S, Ramakrishnan MA.
PMID: 25674602
Virusdisease. 2014;25(3):345-9. doi: 10.1007/s13337-014-0206-z. Epub 2014 Apr 01.

Although the existence of infectious laryngotracheitis virus (ILTV) in India was first reported in 1964, no reports are available regarding its molecular detection and characterization. The present study was aimed to detect and characterize ILTV from recent respiratory disease...

Strategy of Revascularization for Critical Limb Ischemia Due to Infragenicular Lesions-Which Should Be Selected Firstly, Bypass Surgery or Endovascular Therapy?.

Annals of vascular diseases

Ohmine T, Iwasa K, Yamaoka T.
PMID: 26730251
Ann Vasc Dis. 2015;8(4):275-81. doi: 10.3400/avd.oa.15-00076. Epub 2015 Sep 11.

BACKGROUND AND OBJECTIVES: In patients with peripheral arterial diseases (PADs) due to infra-popliteal (below the knee; BTK) lesions, we often encounter situations requiring the immediate selection of either of two revascularization methods, namely bypass surgery or endovascular therapy (EVT)....

Bipartite electronic superstructures in the vortex core of Bi2Sr2CaCu2O8+δ.

Nature communications

Machida T, Kohsaka Y, Matsuoka K, Iwaya K, Hanaguri T, Tamegai T.
PMID: 27230420
Nat Commun. 2016 May 27;7:11747. doi: 10.1038/ncomms11747.

The central issue in the physics of cuprate superconductivity is the mutual relationship among superconductivity, pseudogap and broken-spatial-symmetry states. A magnetic field B suppresses superconductivity, providing an opportunity to investigate the competition among these states. Although various B-induced electronic...

Multifocal BRAF(V600E)-Mutated Melanoma in situ on the Foot.

Case reports in dermatology

Iwama E, Fujimura T, Kusakari Y, Haga T, Aiba S.
PMID: 26594172
Case Rep Dermatol. 2015 Oct 30;7(3):322-7. doi: 10.1159/000441601. eCollection 2015.

Melanoma is an aggressive skin cancer that originates from melanocytes, and about one half of melanoma cases possess a BRAF mutation. Together with PD-L1 expression, the BRAF(V600E) mutation is one of the optimal therapeutic targets for the treatment of...

Erratum: Increased fatty acid synthase expression in prostate biopsy cores predicts higher Gleason score in radical prostatectomy specimen.

BMC clinical pathology

Hamada S, Horiguchi A, Kuroda K, Ito K, Asano T, Miyai K, Iwaya K.
PMID: 25972764
BMC Clin Pathol. 2015 May 13;15:7. doi: 10.1186/s12907-015-0007-3. eCollection 2015.

[This corrects the article DOI: 10.1186/1472-6890-14-3.].

Planar-chiral [7]orthocyclophanes.

Angewandte Chemie (International ed. in English)

Tomooka K, Iso C, Uehara K, Suzuki M, Nishikawa-Shimono R, Igawa K.
PMID: 22976842
Angew Chem Int Ed Engl. 2012 Oct 08;51(41):10355-8. doi: 10.1002/anie.201204484. Epub 2012 Sep 13.

No abstract available.

Germline and somatic mutations of the .

Oncology letters

Kumamoto K, Ishida H, Ohsawa T, Ishibashi K, Ushiama M, Yoshida T, Iwama T.
PMID: 26622826
Oncol Lett. 2015 Oct;10(4):2239-2243. doi: 10.3892/ol.2015.3578. Epub 2015 Aug 06.

Patients with familial adenomatous polyposis (FAP), which is caused by the dysfunction of the adenomatous polyposis coli (APC) protein, have the possibility of developing extracolonic manifestations, including thyroid cancer (TC), congenital hypertrophy of the retinal pigment epithelium, desmoid tumors,...

MK-801 treatment affects glycolysis in oligodendrocytes more than in astrocytes and neuronal cells: insights for schizophrenia.

Frontiers in cellular neuroscience

Guest PC, Iwata K, Kato TA, Steiner J, Schmitt A, Turck CW, Martins-de-Souza D.
PMID: 26029051
Front Cell Neurosci. 2015 May 12;9:180. doi: 10.3389/fncel.2015.00180. eCollection 2015.

Schizophrenia is a debilitating mental disorder, affecting more than 30 million people worldwide. As a multifactorial disease, the underlying causes of schizophrenia require analysis by multiplex methods such as proteomics to allow identification of whole protein networks. Previous post-mortem...

Peer-assisted learning--beyond teaching: How can medical students contribute to the undergraduate curriculum?.

Medical teacher

Furmedge DS, Iwata K, Gill D.
PMID: 25020139
Med Teach. 2014 Sep;36(9):812-7. doi: 10.3109/0142159X.2014.917158. Epub 2014 Jul 14.

INTRODUCTION: Peer-assisted learning (PAL) has become increasingly popular over recent years with many medical schools now formally incorporating peer-teaching programs into the curriculum. PAL has a sound evidence base with benefit to both peer-teacher and peer-learner. Aside from in...

Showing 1 to 12 of 1105 entries