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Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration.

Journal of clinical and experimental hepatology

Mukherjee RM, Shravanti GV, Jakkampudi A, Kota R, Jangala AL, Reddy PB, Rao PN, Gupta R, Reddy DN.
PMID: 25755481
J Clin Exp Hepatol. 2013 Jun;3(2):89-95. doi: 10.1016/j.jceh.2013.04.003. Epub 2013 May 22.

BACKGROUND: High mobility group box1 (HMGB1) and poly(ADP-ribose) polymerase1 (PARP1) proteins repair cellular DNA damage. Reduced expression of the corresponding genes can lead to an impaired DNA damage repair mechanism. Intracellular replication of hepatitis B virus (HBV) in such...

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Mukherjee RM, Shravanti GV, Jakkampudi A, et al. Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration. J Clin Exp Hepatol. 2013;3(2):89-95doi: 10.1016/j.jceh.2013.04.003.
Mukherjee, R. M., Shravanti, G. V., Jakkampudi, A., Kota, R., Jangala, A. L., Reddy, P. B., Rao, P. N., Gupta, R., & Reddy, D. N. (2013). Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration. Journal of clinical and experimental hepatology, 3(2), 89-95. https://doi.org/10.1016/j.jceh.2013.04.003
Mukherjee, Rathindra M, et al. "Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration." Journal of clinical and experimental hepatology vol. 3,2 (2013): 89-95. doi: https://doi.org/10.1016/j.jceh.2013.04.003
Mukherjee RM, Shravanti GV, Jakkampudi A, Kota R, Jangala AL, Reddy PB, Rao PN, Gupta R, Reddy DN. Reduced Expression of DNA Damage Repair Genes High Mobility Group Box1 and Poly(ADP-ribose) Polymerase1 in Inactive Carriers of Hepatitis B Virus Infection-A Possible Stage of Viral Integration. J Clin Exp Hepatol. 2013 Jun;3(2):89-95. doi: 10.1016/j.jceh.2013.04.003. Epub 2013 May 22. PMID: 25755481; PMCID: PMC3940113.
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Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light.

Chemical communications (Cambridge, England)

Komori N, Jakkampudi S, Motoishi R, Abe M, Kamada K, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H, Xue B, Kobayashi T.
PMID: 26515230
Chem Commun (Camb). 2016 Jan 07;52(2):331-4. doi: 10.1039/c5cc07664a. Epub 2015 Oct 30.

A new chromophore, 2-(4-nitrophenyl)benzofuran (NPBF), was designed for two-photon (TP) uncaging using near-IR light. The TP absorption (TPA) cross-sections of the newly designed NPBF chromophore were determined to be 18 GM at 720 nm and 54 GM at 740...

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Komori N, Jakkampudi S, Motoishi R, et al. Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light. Chem Commun (Camb). 2015;52(2):331-4doi: 10.1039/c5cc07664a.
Komori, N., Jakkampudi, S., Motoishi, R., Abe, M., Kamada, K., Furukawa, K., Katan, C., Sawada, W., Takahashi, N., Kasai, H., Xue, B., & Kobayashi, T. (2016). Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light. Chemical communications (Cambridge, England), 52(2), 331-4. https://doi.org/10.1039/c5cc07664a
Komori, Naomitsu, et al. "Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light." Chemical communications (Cambridge, England) vol. 52,2 (2016): 331-4. doi: https://doi.org/10.1039/c5cc07664a
Komori N, Jakkampudi S, Motoishi R, Abe M, Kamada K, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H, Xue B, Kobayashi T. Design and synthesis of a new chromophore, 2-(4-nitrophenyl)benzofuran, for two-photon uncaging using near-IR light. Chem Commun (Camb). 2016 Jan 07;52(2):331-4. doi: 10.1039/c5cc07664a. Epub 2015 Oct 30. PMID: 26515230.
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Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis.

Chemical communications (Cambridge, England)

Bora P, Jakkampudi S, Parella R, Sakkani N, Dai Q, Bihani M, Arman HD, Zhao JC.
PMID: 33928958
Chem Commun (Camb). 2021 May 27;57(43):5334-5337. doi: 10.1039/d1cc01020d.

The cinchona thiourea moiety in the self-assembled modularly designed organocatalysts (MDOs) switches off the iminium catalysis of these catalysts. In this study, it was found that the inhibited iminium catalysis could be switched on by using an appropriate weak...

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Bora P, Jakkampudi S, Parella R, et al. Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis. Chem Commun (Camb). 2021;57(43):5334-5337doi: 10.1039/d1cc01020d.
Bora, P., Jakkampudi, S., Parella, R., Sakkani, N., Dai, Q., Bihani, M., Arman, H. D., & Zhao, J. C. (2021). Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis. Chemical communications (Cambridge, England), 57(43), 5334-5337. https://doi.org/10.1039/d1cc01020d
Bora, Pranjal, et al. "Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis." Chemical communications (Cambridge, England) vol. 57,43 (2021): 5334-5337. doi: https://doi.org/10.1039/d1cc01020d
Bora P, Jakkampudi S, Parella R, Sakkani N, Dai Q, Bihani M, Arman HD, Zhao JC. Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis. Chem Commun (Camb). 2021 May 27;57(43):5334-5337. doi: 10.1039/d1cc01020d. PMID: 33928958.
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Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence.

Journal of clinical and experimental hepatology

Mukherjee RM, Bansode B, Gangwal P, Jakkampudi A, Reddy PB, Rao PN, Gupta R, Nageshwar Reddy D.
PMID: 25755403
J Clin Exp Hepatol. 2012 Mar;2(1):27-34. doi: 10.1016/S0973-6883(12)60080-2. Epub 2012 Apr 12.

BACKGROUND: The interferon regulatory factors (IRFs) are a family of transcription factors known to be involved in the modulation of cellular responses to interferons (IFNs) and viral infection. While IRF-1 acts as a positive regulator, IRF-2 is known to...

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Mukherjee RM, Bansode B, Gangwal P, et al. Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence. J Clin Exp Hepatol. 2012;2(1):27-34doi: 10.1016/S0973-6883(12)60080-2.
Mukherjee, R. M., Bansode, B., Gangwal, P., Jakkampudi, A., Reddy, P. B., Rao, P. N., Gupta, R., & Nageshwar Reddy, D. (2012). Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence. Journal of clinical and experimental hepatology, 2(1), 27-34. https://doi.org/10.1016/S0973-6883(12)60080-2
Mukherjee, Rathindra M, et al. "Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence." Journal of clinical and experimental hepatology vol. 2,1 (2012): 27-34. doi: https://doi.org/10.1016/S0973-6883(12)60080-2
Mukherjee RM, Bansode B, Gangwal P, Jakkampudi A, Reddy PB, Rao PN, Gupta R, Nageshwar Reddy D. Human Interferon Regulatory Factor 2 Gene Expression is Induced in Chronic Hepatitis C Virus Infection-A Possible Mode of Viral Persistence. J Clin Exp Hepatol. 2012 Mar;2(1):27-34. doi: 10.1016/S0973-6883(12)60080-2. Epub 2012 Apr 12. PMID: 25755403; PMCID: PMC3940332.
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Enantioselective Synthesis of Cyclohexenol Derivatives from γ-Aryl-Substituted Enals via an Organocatalyzed Three-Component Reaction.

Organic letters

Majee D, Jakkampudi S, Arman HD, Zhao JC.
PMID: 31670520
Org Lett. 2019 Nov 15;21(22):9166-9170. doi: 10.1021/acs.orglett.9b03532. Epub 2019 Oct 31.

A three-component reaction between γ-aryl-substituted α,β-unsaturated aldehydes and nitroalkenes was realized by using cinchona alkaloid-derived (thio)ureas and squaramides via the dienolate intermediates. This unprecedented 1,3- and 1,5-reactivity of dienolates of the γ-aryl-α,β-unsaturated aldehydes led to the formation of cyclohexenol...

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Majee D, Jakkampudi S, Arman HD, et al. Enantioselective Synthesis of Cyclohexenol Derivatives from γ-Aryl-Substituted Enals via an Organocatalyzed Three-Component Reaction. Org Lett. 2019;21(22):9166-9170doi: 10.1021/acs.orglett.9b03532.
Majee, D., Jakkampudi, S., Arman, H. D., & Zhao, J. C. (2019). Enantioselective Synthesis of Cyclohexenol Derivatives from γ-Aryl-Substituted Enals via an Organocatalyzed Three-Component Reaction. Organic letters, 21(22), 9166-9170. https://doi.org/10.1021/acs.orglett.9b03532
Majee, Debashis, et al. "Enantioselective Synthesis of Cyclohexenol Derivatives from γ-Aryl-Substituted Enals via an Organocatalyzed Three-Component Reaction." Organic letters vol. 21,22 (2019): 9166-9170. doi: https://doi.org/10.1021/acs.orglett.9b03532
Majee D, Jakkampudi S, Arman HD, Zhao JC. Enantioselective Synthesis of Cyclohexenol Derivatives from γ-Aryl-Substituted Enals via an Organocatalyzed Three-Component Reaction. Org Lett. 2019 Nov 15;21(22):9166-9170. doi: 10.1021/acs.orglett.9b03532. Epub 2019 Oct 31. PMID: 31670520.
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Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts.

Advanced synthesis & catalysis

Parella R, Jakkampudi S, Arman H, Zhao JC.
PMID: 31467501
Adv Synth Catal. 2019 Jan 11;361(1):208-213. doi: 10.1002/adsc.201800987. Epub 2018 Oct 30.

A highly stereoselective method for the synthesis of functionalized 3-oxabicyclo[3.3.1]nonan-2-one derivatives with four contiguous stereogenic centers, including one tetrasubstituted stereogenic center, was realized through an organocatalytic domino Michael-hemiacetalization-Michael reaction of (

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Parella R, Jakkampudi S, Arman H, et al. Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts. Adv Synth Catal. 2018;361(1):208-213doi: 10.1002/adsc.201800987.
Parella, R., Jakkampudi, S., Arman, H., & Zhao, J. C. (2019). Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts. Advanced synthesis & catalysis, 361(1), 208-213. https://doi.org/10.1002/adsc.201800987
Parella, Ramarao, et al. "Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts." Advanced synthesis & catalysis vol. 361,1 (2019): 208-213. doi: https://doi.org/10.1002/adsc.201800987
Parella R, Jakkampudi S, Arman H, Zhao JC. Stereoselective Synthesis of 3-Oxabicyclo[3.3.1]nonan-2-ones via a Domino Reaction Catalyzed by Modularly Designed Organocatalysts. Adv Synth Catal. 2019 Jan 11;361(1):208-213. doi: 10.1002/adsc.201800987. Epub 2018 Oct 30. PMID: 31467501; PMCID: PMC6715131.
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Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts.

Chemistry (Weinheim an der Bergstrasse, Germany)

Jakkampudi S, Parella R, Arman HD, Zhao JC.
PMID: 30895663
Chemistry. 2019 Jun 04;25(31):7515-7520. doi: 10.1002/chem.201806447. Epub 2019 May 09.

The diastereodivergent synthesis of hexahydro-6H-benzo[c]chromen-6-one derivatives with good to high diastereoselectivities (up to 98:2 d.r.) and enantioselectivities (up to >99 % ee) has been achieved by using a domino Michael/Michael/hemiacetalization reaction between trans-2-hydroxy-β-nitrostyrenes and trans-7-oxo-5-heptenals followed by oxidation. With...

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Jakkampudi S, Parella R, Arman HD, et al. Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts. Chemistry. 2019;25(31):7515-7520doi: 10.1002/chem.201806447.
Jakkampudi, S., Parella, R., Arman, H. D., & Zhao, J. C. (2019). Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts. Chemistry (Weinheim an der Bergstrasse, Germany), 25(31), 7515-7520. https://doi.org/10.1002/chem.201806447
Jakkampudi, Satish, et al. "Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 25,31 (2019): 7515-7520. doi: https://doi.org/10.1002/chem.201806447
Jakkampudi S, Parella R, Arman HD, Zhao JC. Diastereodivergent Synthesis of Hexahydro-6H-benzo[c]chromen-6-one Derivatives Catalyzed by Modularly Designed Organocatalysts. Chemistry. 2019 Jun 04;25(31):7515-7520. doi: 10.1002/chem.201806447. Epub 2019 May 09. PMID: 30895663; PMCID: PMC6548622.
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Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts.

Organic & biomolecular chemistry

Parella R, Jakkampudi S, Bora P, Sakkani N, Zhao JC.
PMID: 34877959
Org Biomol Chem. 2021 Dec 22;20(1):163-172. doi: 10.1039/d1ob01991k.

The domino Michael/Michael reaction between (

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Parella R, Jakkampudi S, Bora P, et al. Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Org Biomol Chem. 2021;20(1):163-172doi: 10.1039/d1ob01991k.
Parella, R., Jakkampudi, S., Bora, P., Sakkani, N., & Zhao, J. C. (2021). Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Organic & biomolecular chemistry, 20(1), 163-172. https://doi.org/10.1039/d1ob01991k
Parella, Ramarao, et al. "Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts." Organic & biomolecular chemistry vol. 20,1 (2021): 163-172. doi: https://doi.org/10.1039/d1ob01991k
Parella R, Jakkampudi S, Bora P, Sakkani N, Zhao JC. Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Org Biomol Chem. 2021 Dec 22;20(1):163-172. doi: 10.1039/d1ob01991k. PMID: 34877959.
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Enantioselective synthesis of spiro[.

Synthetic communications

Konda S, Jakkampudi S, Arman HD, Zhao JC.
PMID: 33012850
Synth Commun. 2019;49(21):2971-2982. doi: 10.1080/00397911.2019.1651866. Epub 2019 Aug 14.

An efficient stereoselective three-component reaction for the synthesis of functionalized spiro[4

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Konda S, Jakkampudi S, Arman HD, et al. Enantioselective synthesis of spiro[. Synth Commun. 2019;49(21):2971-2982doi: 10.1080/00397911.2019.1651866.
Konda, S., Jakkampudi, S., Arman, H. D., & Zhao, J. C. (2019). Enantioselective synthesis of spiro[. Synthetic communications, 49(21), 2971-2982. https://doi.org/10.1080/00397911.2019.1651866
Konda, Swapna, et al. "Enantioselective synthesis of spiro[." Synthetic communications vol. 49,21 (2019): 2971-2982. doi: https://doi.org/10.1080/00397911.2019.1651866
Konda S, Jakkampudi S, Arman HD, Zhao JC. Enantioselective synthesis of spiro[. Synth Commun. 2019;49(21):2971-2982. doi: 10.1080/00397911.2019.1651866. Epub 2019 Aug 14. PMID: 33012850; PMCID: PMC7530948.
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Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo.

ACS omega

Jakkampudi S, Abe M, Komori N, Takagi R, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H.
PMID: 31457124
ACS Omega. 2016 Aug 09;1(2):193-201. doi: 10.1021/acsomega.6b00119. eCollection 2016 Aug 31.

Among biologically active compounds, calcium ions (Ca

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Jakkampudi S, Abe M, Komori N, et al. Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo. ACS Omega. 2016;1(2):193-201doi: 10.1021/acsomega.6b00119.
Jakkampudi, S., Abe, M., Komori, N., Takagi, R., Furukawa, K., Katan, C., Sawada, W., Takahashi, N., & Kasai, H. (2016). Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo. ACS omega, 1(2), 193-201. https://doi.org/10.1021/acsomega.6b00119
Jakkampudi, Satish, et al. "Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo." ACS omega vol. 1,2 (2016): 193-201. doi: https://doi.org/10.1021/acsomega.6b00119
Jakkampudi S, Abe M, Komori N, Takagi R, Furukawa K, Katan C, Sawada W, Takahashi N, Kasai H. Design and Synthesis of a 4-Nitrobromobenzene Derivative Bearing an Ethylene Glycol Tetraacetic Acid Unit for a New Generation of Caged Calcium Compounds with Two-Photon Absorption Properties in the Near-IR Region and Their Application in Vivo. ACS Omega. 2016 Aug 09;1(2):193-201. doi: 10.1021/acsomega.6b00119. eCollection 2016 Aug 31. PMID: 31457124; PMCID: PMC6640811.
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Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts.

Organic & biomolecular chemistry

Parella R, Jakkampudi S, Bora P, Sakkani N, Zhao JC.
PMID: 34877959
Org Biomol Chem. 2021 Dec 08; doi: 10.1039/d1ob01991k. Epub 2021 Dec 08.

The domino Michael/Michael reaction between (

Cite
Parella R, Jakkampudi S, Bora P, et al. Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Org Biomol Chem. 2021;doi: 10.1039/d1ob01991k.
Parella, R., Jakkampudi, S., Bora, P., Sakkani, N., & Zhao, J. C. (2021). Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Organic & biomolecular chemistry, . https://doi.org/10.1039/d1ob01991k
Parella, Ramarao, et al. "Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts." Organic & biomolecular chemistry vol. (2021). doi: https://doi.org/10.1039/d1ob01991k
Parella R, Jakkampudi S, Bora P, Sakkani N, Zhao JC. Domino Michael/Michael reaction catalyzed by switchable modularly designed organocatalysts. Org Biomol Chem. 2021 Dec 08; doi: 10.1039/d1ob01991k. Epub 2021 Dec 08. PMID: 34877959.
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