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Applications of azo-based probes for imaging retinal hypoxia.

ACS medicinal chemistry letters

Uddin MI, Evans SM, Craft JR, Marnett LJ, Uddin MJ, Jayagopal A.
PMID: 25893047
ACS Med Chem Lett. 2015 Feb 12;6(4):445-9. doi: 10.1021/ml5005206. eCollection 2015 Apr 09.

We report the design and synthesis of an activatable molecular imaging probe to detect hypoxia in mouse models of retinal vascular diseases. Hypoxia of the retina has been associated with the initiation and progression of blinding retinal vascular diseases...

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Uddin MI, Evans SM, Craft JR, et al. Applications of azo-based probes for imaging retinal hypoxia. ACS Med Chem Lett. 2015;6(4):445-9doi: 10.1021/ml5005206.
Uddin, M. I., Evans, S. M., Craft, J. R., Marnett, L. J., Uddin, M. J., & Jayagopal, A. (2015). Applications of azo-based probes for imaging retinal hypoxia. ACS medicinal chemistry letters, 6(4), 445-9. https://doi.org/10.1021/ml5005206
Uddin, Md Imam, et al. "Applications of azo-based probes for imaging retinal hypoxia." ACS medicinal chemistry letters vol. 6,4 (2015): 445-9. doi: https://doi.org/10.1021/ml5005206
Uddin MI, Evans SM, Craft JR, Marnett LJ, Uddin MJ, Jayagopal A. Applications of azo-based probes for imaging retinal hypoxia. ACS Med Chem Lett. 2015 Feb 12;6(4):445-9. doi: 10.1021/ml5005206. eCollection 2015 Apr 09. PMID: 25893047; PMCID: PMC4394343.
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Does abscisic acid influence proline accumulation in stressed leaves?.

Planta

Rajagopal V, Andersen AS.
PMID: 24408265
Planta. 1978 Jan;143(1):85-8. doi: 10.1007/BF00389056.

Root treatments of barley (Hordeum distichum L.) plants with 10(-7) to 10(-4) M abscisic acid (ABA) caused an increase in proline content, especially at higher concentrations, within 2-3 h. Even 3 h after the removal of ABA from the...

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Rajagopal V, Andersen AS. Does abscisic acid influence proline accumulation in stressed leaves?. Planta. 1978;143(1):85-8doi: 10.1007/BF00389056.
Rajagopal, V., & Andersen, A. S. (1978). Does abscisic acid influence proline accumulation in stressed leaves?. Planta, 143(1), 85-8. https://doi.org/10.1007/BF00389056
Rajagopal, V, and Andersen, A S. "Does abscisic acid influence proline accumulation in stressed leaves?." Planta vol. 143,1 (1978): 85-8. doi: https://doi.org/10.1007/BF00389056
Rajagopal V, Andersen AS. Does abscisic acid influence proline accumulation in stressed leaves?. Planta. 1978 Jan;143(1):85-8. doi: 10.1007/BF00389056. PMID: 24408265.
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Trapped ion chain thermometry and mass spectrometry through imaging.

European journal of mass spectrometry (Chichester, England)

Rajagopal V, Marler JP, Kokish MG, Odom BC.
PMID: 26863070
Eur J Mass Spectrom (Chichester). 2016;22(1):1-7. doi: 10.1255/ejms.1408.

We demonstrate a spatial-imaging thermometry technique for ions in a one-dimensional Coulomb crystal by relating their imaged spatial extent along the linear radiofrequency ion trap axis to normal modes of vibration of coupled oscillators in a harmonic potential. We...

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Rajagopal V, Marler JP, Kokish MG, et al. Trapped ion chain thermometry and mass spectrometry through imaging. Eur J Mass Spectrom (Chichester). 2016;22(1):1-7doi: 10.1255/ejms.1408.
Rajagopal, V., Marler, J. P., Kokish, M. G., & Odom, B. C. (2016). Trapped ion chain thermometry and mass spectrometry through imaging. European journal of mass spectrometry (Chichester, England), 22(1), 1-7. https://doi.org/10.1255/ejms.1408
Rajagopal, Vaishnavi, et al. "Trapped ion chain thermometry and mass spectrometry through imaging." European journal of mass spectrometry (Chichester, England) vol. 22,1 (2016): 1-7. doi: https://doi.org/10.1255/ejms.1408
Rajagopal V, Marler JP, Kokish MG, Odom BC. Trapped ion chain thermometry and mass spectrometry through imaging. Eur J Mass Spectrom (Chichester). 2016;22(1):1-7. doi: 10.1255/ejms.1408. PMID: 26863070.
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Systemic effects of inhaled corticosteroids: an overview.

The open respiratory medicine journal

Pandya D, Puttanna A, Balagopal V.
PMID: 25674175
Open Respir Med J. 2014 Dec 31;8:59-65. doi: 10.2174/1874306401408010059. eCollection 2014.

Inhaled corticosteroids (ICS) are common medications, used in respiratory medicine for controlling conditions such as asthma and other obstructive airway diseases. The systemic effects of oral corticosteroids are well known and established; inhaled steroids have been known to cause...

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Pandya D, Puttanna A, Balagopal V. Systemic effects of inhaled corticosteroids: an overview. Open Respir Med J. 2014;8:59-65doi: 10.2174/1874306401408010059.
Pandya, D., Puttanna, A., & Balagopal, V. (2014). Systemic effects of inhaled corticosteroids: an overview. The open respiratory medicine journal, 859-65. https://doi.org/10.2174/1874306401408010059
Pandya, Dhruti, et al. "Systemic effects of inhaled corticosteroids: an overview." The open respiratory medicine journal vol. 8 (2014): 59-65. doi: https://doi.org/10.2174/1874306401408010059
Pandya D, Puttanna A, Balagopal V. Systemic effects of inhaled corticosteroids: an overview. Open Respir Med J. 2014 Dec 31;8:59-65. doi: 10.2174/1874306401408010059. eCollection 2014. PMID: 25674175; PMCID: PMC4319197.
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An uncommon cause of pyrexia of unknown origin.

Acute medicine

Rajagopal V, Collins J, Carroll C, Burroughs S.
PMID: 21607217
Acute Med. 2008;7(3):137-9.

Prolonged unexplained fever is one of the most challenging problems encountered in clinical medicine. We report the case of a patient with an uncommon cause of Pyrexia of Unknown Origin (PUO).

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Rajagopal V, Collins J, Carroll C, et al. An uncommon cause of pyrexia of unknown origin. Acute Med. 2008;7(3):137-9
Rajagopal, V., Collins, J., Carroll, C., & Burroughs, S. (2008). An uncommon cause of pyrexia of unknown origin. Acute medicine, 7(3), 137-9.
Rajagopal, Vivek, et al. "An uncommon cause of pyrexia of unknown origin." Acute medicine vol. 7,3 (2008): 137-9.
Rajagopal V, Collins J, Carroll C, Burroughs S. An uncommon cause of pyrexia of unknown origin. Acute Med. 2008;7(3):137-9. PMID: 21607217.
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Biochemical and genetic studies on cardiometabolic syndrome.

Indian journal of clinical biochemistry : IJCB

Supriya Simon A, Dinesh Roy D, Jayapal V, Vijayakumar T.
PMID: 23105904
Indian J Clin Biochem. 2010 Apr;25(2):164-8. doi: 10.1007/s12291-010-0030-1. Epub 2010 May 27.

Cardiometabolic syndrome is one of the major public health issues of this century which describes a cluster of clinical characteristics. Seventy two patients with coronary artery disease (CAD) and cardiometabolic syndrome and forty healthy age and sex matched normal...

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Supriya Simon A, Dinesh Roy D, Jayapal V, et al. Biochemical and genetic studies on cardiometabolic syndrome. Indian J Clin Biochem. 2010;25(2):164-8doi: 10.1007/s12291-010-0030-1.
Supriya Simon, A., Dinesh Roy, D., Jayapal, V., & Vijayakumar, T. (2010). Biochemical and genetic studies on cardiometabolic syndrome. Indian journal of clinical biochemistry : IJCB, 25(2), 164-8. https://doi.org/10.1007/s12291-010-0030-1
Supriya Simon, A, et al. "Biochemical and genetic studies on cardiometabolic syndrome." Indian journal of clinical biochemistry : IJCB vol. 25,2 (2010): 164-8. doi: https://doi.org/10.1007/s12291-010-0030-1
Supriya Simon A, Dinesh Roy D, Jayapal V, Vijayakumar T. Biochemical and genetic studies on cardiometabolic syndrome. Indian J Clin Biochem. 2010 Apr;25(2):164-8. doi: 10.1007/s12291-010-0030-1. Epub 2010 May 27. PMID: 23105904; PMCID: PMC3453103.
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Erythrocyte β spectrin can be genetically targeted to protect mice from malaria.

Blood advances

Lelliott PM, Huang HM, Dixon MW, Namvar A, Blanch AJ, Rajagopal V, Tilley L, Coban C, McMorran BJ, Foote SJ, Burgio G.
PMID: 29296915
Blood Adv. 2017 Dec 12;1(26):2624-2636. doi: 10.1182/bloodadvances.2017009274. eCollection 2017 Dec 12.

The malaria parasite hijacks host erythrocytes to shield itself from the immune system and proliferate. Red blood cell abnormalities can provide protection from malaria by impeding parasite invasion and growth within the cell or by compromising the ability of...

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Lelliott PM, Huang HM, Dixon MW, et al. Erythrocyte β spectrin can be genetically targeted to protect mice from malaria. Blood Adv. 2017;1(26):2624-2636doi: 10.1182/bloodadvances.2017009274.
Lelliott, P. M., Huang, H. M., Dixon, M. W., Namvar, A., Blanch, A. J., Rajagopal, V., Tilley, L., Coban, C., McMorran, B. J., Foote, S. J., & Burgio, G. (2017). Erythrocyte β spectrin can be genetically targeted to protect mice from malaria. Blood advances, 1(26), 2624-2636. https://doi.org/10.1182/bloodadvances.2017009274
Lelliott, Patrick M, et al. "Erythrocyte β spectrin can be genetically targeted to protect mice from malaria." Blood advances vol. 1,26 (2017): 2624-2636. doi: https://doi.org/10.1182/bloodadvances.2017009274
Lelliott PM, Huang HM, Dixon MW, Namvar A, Blanch AJ, Rajagopal V, Tilley L, Coban C, McMorran BJ, Foote SJ, Burgio G. Erythrocyte β spectrin can be genetically targeted to protect mice from malaria. Blood Adv. 2017 Dec 12;1(26):2624-2636. doi: 10.1182/bloodadvances.2017009274. eCollection 2017 Dec 12. PMID: 29296915; PMCID: PMC5728631.
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Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release.

Frontiers in physiology

Ladd D, Tilūnaitė A, Roderick HL, Soeller C, Crampin EJ, Rajagopal V.
PMID: 31632297
Front Physiol. 2019 Oct 02;10:1263. doi: 10.3389/fphys.2019.01263. eCollection 2019.

Calcium signaling plays a pivotal role in cardiomyocytes, coupling electrical excitation to mechanical contraction of the heart. Determining locations of active calcium release sites, and how their recruitment changes in response to stimuli and in disease states is therefore...

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Ladd D, Tilūnaitė A, Roderick HL, et al. Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release. Front Physiol. 2019;10:1263doi: 10.3389/fphys.2019.01263.
Ladd, D., Tilūnaitė, A., Roderick, H. L., Soeller, C., Crampin, E. J., & Rajagopal, V. (2019). Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release. Frontiers in physiology, 101263. https://doi.org/10.3389/fphys.2019.01263
Ladd, David, et al. "Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release." Frontiers in physiology vol. 10 (2019): 1263. doi: https://doi.org/10.3389/fphys.2019.01263
Ladd D, Tilūnaitė A, Roderick HL, Soeller C, Crampin EJ, Rajagopal V. Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release. Front Physiol. 2019 Oct 02;10:1263. doi: 10.3389/fphys.2019.01263. eCollection 2019. PMID: 31632297; PMCID: PMC6783691.
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Assessment of Serum Selenium and Ceruloplasmin in Potentially Malignant Disorders and Oral Cancer.

Journal of pharmacy & bioallied sciences

Mampilly MO, Ravindran N, Parambil MS, Nilesh K, Jayagopalan P, Dhamali D.
PMID: 35017913
J Pharm Bioallied Sci. 2021 Nov;13:S989-S992. doi: 10.4103/jpbs.jpbs_380_21. Epub 2021 Nov 10.

INTRODUCTION: Despite extensive research and development, potentially malignant disorders (PMDs) of the oral cavity and oral cancer remain a serious concern. Diet and immunity have been identified as important modifiable factors in such diseases.MATERIALS AND METHODS: A total of...

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Mampilly MO, Ravindran N, Parambil MS, et al. Assessment of Serum Selenium and Ceruloplasmin in Potentially Malignant Disorders and Oral Cancer. J Pharm Bioallied Sci. 2021;13:S989-S992doi: 10.4103/jpbs.jpbs_380_21.
Mampilly, M. O., Ravindran, N., Parambil, M. S., Nilesh, K., Jayagopalan, P., & Dhamali, D. (2021). Assessment of Serum Selenium and Ceruloplasmin in Potentially Malignant Disorders and Oral Cancer. Journal of pharmacy & bioallied sciences, 13S989-S992. https://doi.org/10.4103/jpbs.jpbs_380_21
Mampilly, Mathew O, et al. "Assessment of Serum Selenium and Ceruloplasmin in Potentially Malignant Disorders and Oral Cancer." Journal of pharmacy & bioallied sciences vol. 13 (2021): S989-S992. doi: https://doi.org/10.4103/jpbs.jpbs_380_21
Mampilly MO, Ravindran N, Parambil MS, Nilesh K, Jayagopalan P, Dhamali D. Assessment of Serum Selenium and Ceruloplasmin in Potentially Malignant Disorders and Oral Cancer. J Pharm Bioallied Sci. 2021 Nov;13:S989-S992. doi: 10.4103/jpbs.jpbs_380_21. Epub 2021 Nov 10. PMID: 35017913; PMCID: PMC8686891.
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Exome sequencing and analysis of 454,787 UK Biobank participants.

Nature

Backman JD, Li AH, Marcketta A, Sun D, Mbatchou J, Kessler MD, Benner C, Liu D, Locke AE, Balasubramanian S, Yadav A, Banerjee N, Gillies CE, Damask A, Liu S, Bai X, Hawes A, Maxwell E, Gurski L, Watanabe K, Kosmicki JA, Rajagopal V, Mighty J, Jones M, Mitnaul L, Stahl E, Coppola G, Jorgenson E, Habegger L, Salerno WJ, Shuldiner AR, Lotta LA, Overton JD, Cantor MN, Reid JG, Yancopoulos G, Kang HM, Marchini J, Baras A, Abecasis GR, Ferreira MAR.
PMID: 34662886
Nature. 2021 Nov;599(7886):628-634. doi: 10.1038/s41586-021-04103-z. Epub 2021 Oct 18.

A major goal in human genetics is to use natural variation to understand the phenotypic consequences of altering each protein-coding gene in the genome. Here we used exome sequencing

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Backman JD, Li AH, Marcketta A, et al. Exome sequencing and analysis of 454,787 UK Biobank participants. Nature. 2021;599(7886):628-634doi: 10.1038/s41586-021-04103-z.
Backman, J. D., Li, A. H., Marcketta, A., Sun, D., Mbatchou, J., Kessler, M. D., Benner, C., Liu, D., Locke, A. E., Balasubramanian, S., Yadav, A., Banerjee, N., Gillies, C. E., Damask, A., Liu, S., Bai, X., Hawes, A., Maxwell, E., Gurski, L., Watanabe, K., Kosmicki, J. A., Rajagopal, V., Mighty, J., Jones, M., Mitnaul, L., Stahl, E., Coppola, G., Jorgenson, E., Habegger, L., Salerno, W. J., Shuldiner, A. R., Lotta, L. A., Overton, J. D., Cantor, M. N., Reid, J. G., Yancopoulos, G., Kang, H. M., Marchini, J., Baras, A., Abecasis, G. R., & Ferreira, M. A. R. (2021). Exome sequencing and analysis of 454,787 UK Biobank participants. Nature, 599(7886), 628-634. https://doi.org/10.1038/s41586-021-04103-z
Backman, Joshua D, et al. "Exome sequencing and analysis of 454,787 UK Biobank participants." Nature vol. 599,7886 (2021): 628-634. doi: https://doi.org/10.1038/s41586-021-04103-z
Backman JD, Li AH, Marcketta A, Sun D, Mbatchou J, Kessler MD, Benner C, Liu D, Locke AE, Balasubramanian S, Yadav A, Banerjee N, Gillies CE, Damask A, Liu S, Bai X, Hawes A, Maxwell E, Gurski L, Watanabe K, Kosmicki JA, Rajagopal V, Mighty J, Jones M, Mitnaul L, Stahl E, Coppola G, Jorgenson E, Habegger L, Salerno WJ, Shuldiner AR, Lotta LA, Overton JD, Cantor MN, Reid JG, Yancopoulos G, Kang HM, Marchini J, Baras A, Abecasis GR, Ferreira MAR. Exome sequencing and analysis of 454,787 UK Biobank participants. Nature. 2021 Nov;599(7886):628-634. doi: 10.1038/s41586-021-04103-z. Epub 2021 Oct 18. PMID: 34662886; PMCID: PMC8596853.
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Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis.

Clinical epidemiology and global health

Kushwaha S, Khanna P, Rajagopal V, Kiran T.
PMID: 34079918
Clin Epidemiol Glob Health. 2021 Jul-Sep;11:100788. doi: 10.1016/j.cegh.2021.100788. Epub 2021 May 28.

BACKGROUND: The associated risk factors, co-morbid conditions and biological differences varying with gender and age might be the cause of higher COVID-19 infection and deaths among males and older persons. The objective of this study was to predict and...

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Kushwaha S, Khanna P, Rajagopal V, et al. Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis. Clin Epidemiol Glob Health. 2021;11:100788doi: 10.1016/j.cegh.2021.100788.
Kushwaha, S., Khanna, P., Rajagopal, V., & Kiran, T. (2021). Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis. Clinical epidemiology and global health, 11100788. https://doi.org/10.1016/j.cegh.2021.100788
Kushwaha, Savitesh, et al. "Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis." Clinical epidemiology and global health vol. 11 (2021): 100788. doi: https://doi.org/10.1016/j.cegh.2021.100788
Kushwaha S, Khanna P, Rajagopal V, Kiran T. Biological attributes of age and gender variations in Indian COVID-19 cases: A retrospective data analysis. Clin Epidemiol Glob Health. 2021 Jul-Sep;11:100788. doi: 10.1016/j.cegh.2021.100788. Epub 2021 May 28. PMID: 34079918; PMCID: PMC8159626.
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GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging.

The Journal of nutrition

Sekhar RV.
PMID: 34587244
J Nutr. 2021 Dec 03;151(12):3606-3616. doi: 10.1093/jn/nxab309.

Cellular increases in oxidative stress (OxS) and decline in mitochondrial function are identified as key defects in aging, but underlying mechanisms are poorly understood and interventions are lacking. Defects linked to OxS and impaired mitochondrial fuel oxidation, such as...

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Sekhar RV. GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging. J Nutr. 2021;151(12):3606-3616doi: 10.1093/jn/nxab309.
Sekhar, R. V. (2021). GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging. The Journal of nutrition, 151(12), 3606-3616. https://doi.org/10.1093/jn/nxab309
Sekhar, Rajagopal V. "GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging." The Journal of nutrition vol. 151,12 (2021): 3606-3616. doi: https://doi.org/10.1093/jn/nxab309
Sekhar RV. GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging. J Nutr. 2021 Dec 03;151(12):3606-3616. doi: 10.1093/jn/nxab309. PMID: 34587244.
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Showing 1 to 12 of 67 entries