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Showing 1 to 12 of 1114 entries
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Sphingosine-1 phosphate receptor (S1p1), a critical receptor controlling human lymphocyte trafficking, is expressed in hen and human ovaries and ovarian tumors.

Journal of ovarian research

Bradaric MJ, Barua A, Penumatsa K, Yi Y, Edassery SL, Sharma S, Abramowicz JS, Bahr JM, Luborsky JL.
PMID: 21356044
J Ovarian Res. 2011 Feb 28;4(1):4. doi: 10.1186/1757-2215-4-4.

BACKGROUND: Sphingosine-1 receptor 1 (S1P1) plays a major role in regulating lymphocyte egress from peripheral lymph tissue. Lymphocyte trafficking is potentially a critical response to tumors and to tumor vaccines. Also, the receptor has been shown to influence metastasis....

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

NPJ breast cancer

Wolf DM, Yau C, Sanil A, Glas A, Petricoin E, Wulfkuhle J, Severson TM, Linn S, Brown-Swigart L, Hirst G, Buxton M, DeMichele A, Hylton N, Symmans F, Yee D, Paoloni M, Esserman L, Berry D, Rugo H, Olopade O, van 't Veer L.
PMID: 28948212
NPJ Breast Cancer. 2017 Aug 25;3:31. doi: 10.1038/s41523-017-0025-7. eCollection 2017.

Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature. However, not all triple negative patients achieved pathologic complete response...

Physical Exercise Preserves Adult Visual Plasticity in Mice and Restores it after a Stroke in the Somatosensory Cortex.

Frontiers in aging neuroscience

Kalogeraki E, Pielecka-Fortuna J, Hüppe JM, Löwel S.
PMID: 27708575
Front Aging Neurosci. 2016 Sep 21;8:212. doi: 10.3389/fnagi.2016.00212. eCollection 2016.

The primary visual cortex (V1) is widely used to study brain plasticity, which is not only crucial for normal brain function, such as learning and memory, but also for recovery after brain injuries such as stroke. In standard cage...

Structural Dynamics upon Photoexcitation in a Spin Crossover Crystal Probed with Femtosecond Electron Diffraction.

Angewandte Chemie (International ed. in English)

Jiang Y, Liu LC, Müller-Werkmeister HM, Lu C, Zhang D, Field RL, Sarracini A, Moriena G, Collet E, Miller RJD.
PMID: 28510325
Angew Chem Int Ed Engl. 2017 Jun 12;56(25):7130-7134. doi: 10.1002/anie.201702497. Epub 2017 May 16.

Photoexcitation of spin crossover (SCO) complexes can trigger extensive electronic spin transitions and transformation of molecular structure. However, the precise nature of the associated ultrafast structural dynamics remains elusive, especially in the solid state. Here, we studied a single-crystal...

Metabolic Vulnerability in the Neurodegenerative Disease Glaucoma.

Frontiers in neuroscience

Inman DM, Harun-Or-Rashid M.
PMID: 28424571
Front Neurosci. 2017 Mar 30;11:146. doi: 10.3389/fnins.2017.00146. eCollection 2017.

Axons can be several orders of magnitude longer than neural somas, presenting logistical difficulties in cargo trafficking and structural maintenance. Keeping the axon compartment well supplied with energy also presents a considerable challenge; even seemingly subtle modifications of metabolism...

My Interventional Drug-Eluting Stent Educational App (MyIDEA): Patient-Centered Design Methodology.

JMIR mHealth and uHealth

Boyd AD, Moores K, Shah V, Sadhu E, Shroff A, Groo V, Dickens C, Field J, Baumann M, Welland B, Gutowski G, Flores JD, Zhao Z, Bahroos N, Hynes DM, Wilkie DJ.
PMID: 26139587
JMIR Mhealth Uhealth. 2015 Jul 02;3(3):e74. doi: 10.2196/mhealth.4021.

BACKGROUND: Patient adherence to medication regimens is critical in most chronic disease treatment plans. This study uses a patient-centered tablet app, "My Interventional Drug-Eluting Stent Educational App (MyIDEA)." This is an educational program designed to improve patient medication adherence.OBJECTIVE:...

Should we think about wrist extensor after flexor tendon repair?.

SAGE open medicine

Ferreira AM, Fonseca MC, Tanaka DM, Barbosa RI, Marcolino AM, Elui VM, Mazzer N.
PMID: 26770674
SAGE Open Med. 2013 Jul 24;1:2050312113494974. doi: 10.1177/2050312113494974. eCollection 2013.

OBJECTIVE: To evaluate the activity of wrist extensor muscle, correlating with wrist motion during gripping after flexor tendon repair.DESIGN: Cross-sectional clinical measurement study.SETTING: Laboratory for biomechanics and rehabilitation.SUBJECTS: A total of 11 patients submitted to rehabilitation by early passive...

Characterization of B cells in muscle-specific kinase antibody myasthenia gravis.

Neurology(R) neuroimmunology & neuroinflammation

Guptill JT, Yi JS, Sanders DB, Guidon AC, Juel VC, Massey JM, Howard JF, Scuderi F, Bartoccioni E, Evoli A, Weinhold KJ.
PMID: 25745635
Neurol Neuroimmunol Neuroinflamm. 2015 Feb 26;2(2):e77. doi: 10.1212/NXI.0000000000000077. eCollection 2015 Apr.

OBJECTIVE: To characterize B-cell subsets in patients with muscle-specific tyrosine kinase (MuSK) myasthenia gravis (MG).METHODS: In accordance with Human Immunology Project Consortium guidelines, we performed polychromatic flow cytometry and ELISA assays in peripheral blood samples from 18 patients with...

A multiplex PCR for rapid identification of .

Plant methods

Koh JCO, Barbulescu DM, Norton S, Redden B, Salisbury PA, Kaur S, Cogan N, Slater AT.
PMID: 28638437
Plant Methods. 2017 Jun 15;13:49. doi: 10.1186/s13007-017-0200-8. eCollection 2017.

BACKGROUND: Within the Brassicaceae, six species from the genus RESULTS: A multiplex polymerase chain reaction (MPCR) consisting of new and existing primers specific to the CONCLUSION: A cheap and fast multiplex PCR assay for identification of

Antioxidant and Nephroprotective Activities of Aconitum heterophyllum Root in Glycerol Induced Acute Renal Failure in Rats.

Journal of clinical and diagnostic research : JCDR

Konda VG, Eerike M, Raghuraman LP, Rajamanickam MK.
PMID: 27134892
J Clin Diagn Res. 2016 Mar;10(3):FF01-2. doi: 10.7860/JCDR/2016/10798.7388. Epub 2016 Mar 01.

AIM: The present study was to evaluate the antioxidant and nephroprotective activities of ethanolic extract of Aconitum heterophyllum root (EEAHR) in glycerol induced acute renal failure (ARF) in Wistar albino rats.MATERIALS AND METHODS: In vitro antioxidant activity of EEAHR...

RESOURCE PREDICTABILITY AND NICHE BREADTH IN THE DROSOPHILA QUINARIA SPECIES GROUP.

Evolution; international journal of organic evolution

Jaenike J.
PMID: 28567956
Evolution. 1978 Sep;32(3):676-678. doi: 10.1111/j.1558-5646.1978.tb04613.x.

No abstract available.

Using qualitative methods to access the pain experience.

British journal of pain

Morse JM.
PMID: 26516553
Br J Pain. 2015 Feb;9(1):26-31. doi: 10.1177/2049463714550507.

Qualitative methods provide us with techniques to access the pain experience of patients in ways that provide explanation for apparent contradictions and idiosyncrasies that are difficult to access. In this article, I review three such strategies and the application...

Showing 1 to 12 of 1114 entries