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Showing 1 to 12 of 211 entries
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Intraductal cisplatin treatment in a .

Oncotarget

de Groot JS, van Diest PJ, van Amersfoort M, Vlug EJ, Pan X, Ter Hoeve ND, Rosing H, Beijnen JH, Youssef SA, de Bruin A, Jonkers J, van der Wall E, Derksen PWB.
PMID: 28977823
Oncotarget. 2017 Jun 15;8(37):60750-60763. doi: 10.18632/oncotarget.18490. eCollection 2017 Sep 22.

No abstract available.

Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

Oncotarget

Borst GR, Kumareswaran R, Yücel H, Telli S, Do T, McKee T, Zafarana G, Jonkers J, Verheij M, O'Connor MJ, Rottenberg S, Bristow RG.
PMID: 29152107
Oncotarget. 2017 Sep 15;8(50):87638-87646. doi: 10.18632/oncotarget.20936. eCollection 2017 Oct 20.

Clinical trials are studying the benefits of combining the PARP-1 inhibitor olaparib with chemotherapy and radiotherapy treatment in a variety of cancer increasing the therapeutic ratio for olaparib may come from its ability to modify the tumour microenvironment by...

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

Cell reports

de Vries NA, Hulsman D, Akhtar W, de Jong J, Miles DC, Blom M, van Tellingen O, Jonkers J, van Lohuizen M.
PMID: 25600873
Cell Rep. 2015 Jan 20;10(3):383-397. doi: 10.1016/j.celrep.2014.12.028. Epub 2015 Jan 15.

EZH2 is frequently overexpressed in glioblastoma (GBM), suggesting an oncogenic function that could be a target for therapeutic intervention. However, reduced EZH2 activity can also promote tumorigenesis, leading to concerns about the use of EZH2 inhibitors. Here, we provide...

Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.

Nature

Chaudhuri AR, Callen E, Ding X, Gogola E, Duarte AA, Lee JE, Wong N, Lafarga V, Calvo JA, Panzarino NJ, John S, Day A, Crespo AV, Shen B, Starnes LM, de Ruiter JR, Daniel JA, Konstantinopoulos PA, Cortez D, Cantor SB, Fernandez-Capetillo O, Ge K, Jonkers J, Rottenberg S, Sharan SK, Nussenzweig A.
PMID: 27680696
Nature. 2016 Nov 17;539(7629):456. doi: 10.1038/nature19826. Epub 2016 Sep 28.

No abstract available.

The Differential Effect of Arm Movements during Gait on the Forward Acceleration of the Centre of Mass in Children with Cerebral Palsy and Typically Developing Children.

Frontiers in human neuroscience

Meyns P, Molenaers G, Duysens J, Jonkers I.
PMID: 28298890
Front Hum Neurosci. 2017 Mar 01;11:96. doi: 10.3389/fnhum.2017.00096. eCollection 2017.

No abstract available.

A fast and activatable cross-linking strategy for hydrogel formation.

Advanced materials (Deerfield Beach, Fla.)

Jonker AM, Borrmann A, van Eck ER, van Delft FL, Löwik DW, van Hest JC.
PMID: 25535032
Adv Mater. 2015 Feb 18;27(7):1235-40. doi: 10.1002/adma.201404448. Epub 2014 Dec 23.

Strain-promoted oxidation-controlled cyclo-octyne-1,2-quinone cycloaddition (SPOCQ) is a fast and activatable cross-linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to the fast reaction kinetics,...

Capsule-like assemblies in polar solvents.

The Journal of organic chemistry

Zadmard R, Junkers M, Schrader T, Grawe T, Kraft A.
PMID: 12919011
J Org Chem. 2003 Aug 22;68(17):6511-21. doi: 10.1021/jo034592q.

Calix[4]arene derivatives with four anionic groups at their upper rim form discrete 1:1 complexes with complementary calix[4]arene derivatives bearing four cationic groups at their upper rim. Each cation is bound by two anions, and vice versa, in a mutual...

Digital archives: Don't let copyright block data mining.

Nature

Jockers ML, Sag M, Schultz J.
PMID: 23038448
Nature. 2012 Oct 04;490(7418):29-30. doi: 10.1038/490029a.

No abstract available.

Computed tomography-based joint locations affect calculation of joint moments during gait when compared to scaling approaches.

Computer methods in biomechanics and biomedical engineering

Bartels W, Demol J, Gelaude F, Jonkers I, Vander Sloten J.
PMID: 24641349
Comput Methods Biomech Biomed Engin. 2015 Aug;18(11):1238-1251. doi: 10.1080/10255842.2014.890186. Epub 2014 Mar 18.

Hip joint moments are an important parameter in the biomechanical evaluation of orthopaedic surgery. Joint moments are generally calculated using scaled generic musculoskeletal models. However, due to anatomical variability or pathology, such models may differ from the patient's anatomy,...

Psychosocial care and education of the cancer patient: strengthening the physician's role.

Patient education and counseling

Cuisinier MC, Dokter HJ, Jonkers R, Van Eijk JT.
PMID: 10300737
Patient Educ Couns. 1986 Mar;8(1):5-16. doi: 10.1016/0738-3991(86)90022-4.

Psychosocial support and education of cancer patients is a difficult task for many physicians. Patients are much in need of this kind of help, but the confrontation with cancer is not an easy one for most people, including physicians....

OpenSim Versus Human Body Model: A Comparison Study for the Lower Limbs During Gait.

Journal of applied biomechanics

Falisse A, Van Rossom S, Gijsbers J, Steenbrink F, van Basten BJH, Jonkers I, van den Bogert AJ, De Groote F.
PMID: 29809082
J Appl Biomech. 2018 Nov 21;1-7. doi: 10.1123/jab.2017-0156. Epub 2018 Nov 21.

Musculoskeletal modeling and simulations have become popular tools for analyzing human movements. However, end users are often not aware of underlying modeling and computational assumptions. This study investigates how these assumptions affect biomechanical gait analysis outcomes performed with Human...

Hospitalization-associated disability in older adults with valvular heart disease: incidence, risk factors and its association with care processes.

Acta cardiologica

Jonckers M, Van Grootven B, Willemyns E, Hornikx M, Jeuris A, Dubois C, Herregods MC, Deschodt M.
PMID: 29301463
Acta Cardiol. 2018 Jan 04;1-7. doi: 10.1080/00015385.2017.1421300. Epub 2018 Jan 04.

BACKGROUND: The aim of this study was to determine the incidence and recovery of hospitalisation-associated disability (HAD), the associated risk factors, and the link with care processes in patients aged 70 years or older hospitalised with valvular heart disease...

Showing 1 to 12 of 211 entries