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Showing 1 to 12 of 176 entries
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ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches.

Pharmacogenomics and personalized medicine

Cleophas MC, Joosten LA, Stamp LK, Dalbeth N, Woodward OM, Merriman TR.
PMID: 28461764
Pharmgenomics Pers Med. 2017 Apr 20;10:129-142. doi: 10.2147/PGPM.S105854. eCollection 2017.

As a result of the association of a common polymorphism (

Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis.

Frontiers in microbiology

Rosentul DC, Delsing CE, Jaeger M, Plantinga TS, Oosting M, Costantini I, Venselaar H, Joosten LA, van der Meer JW, Dupont B, Kullberg BJ, Sobel JD, Netea MG.
PMID: 25295030
Front Microbiol. 2014 Sep 23;5:483. doi: 10.3389/fmicb.2014.00483. eCollection 2014.

OBJECTIVE: Approximately 5% of women suffer from recurrent vulvovaginal candidiasis (RVVC). It has been hypothesized that genetic factors play an important role in the susceptibility to RVVC. The aim of this study was to assess the effect of genetic...

Defensive properties of pyrrolizidine alkaloids against microorganisms.

Phytochemistry reviews : proceedings of the Phytochemical Society of Europe

Joosten L, van Veen JA.
PMID: 21475390
Phytochem Rev. 2011 Mar;10(1):127-136. doi: 10.1007/s11101-010-9204-y. Epub 2010 Nov 23.

The understanding of the selection factors that drive chemical diversification of secondary metabolites of constitutive defence systems in plants, such as pyrrolizidine alkaloids (PAs), is still incomplete. Historically, plants always have been confronted with microorganisms. Long before herbivores existed...

Copper(I)-assembled [3]rotaxane whose two rings act as flapping wings.

Journal of the American Chemical Society

Joosten A, Trolez Y, Collin JP, Heitz V, Sauvage JP.
PMID: 22236438
J Am Chem Soc. 2012 Jan 25;134(3):1802-9. doi: 10.1021/ja210113y. Epub 2012 Jan 10.

A new copper-complexed [3]rotaxane consisting of two coordinating 30-membered rings threaded by a two-binding-site axis has been prepared in good yield from relatively simple organic fragments. The main specificity of the system originates from the stoppering reaction, based on...

Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell.

Chemistry (Weinheim an der Bergstrasse, Germany)

Nierengarten JF, Schneider JP, Trinh TMN, Joosten A, Holler M, Lepage ML, Bodlenner A, García-Moreno MI, Ortiz Mellet C, Compain P.
PMID: 29281149
Chemistry. 2018 Feb 16;24(10):2483-2492. doi: 10.1002/chem.201705600. Epub 2018 Jan 25.

The multivalent effect in glycosidase inhibition is a new topic in glycoscience that has emerged a few years ago, with the discovery of neoglycoclusters displaying strong binding enhancements over the corresponding monovalent inhibitor. Iminosugar-fullerene conjugates with high valencies have...

A Randomized Controlled Trial of a Play-Based, Peer-Mediated Pragmatic Language Intervention for Children With Autism.

Frontiers in psychology

Parsons L, Cordier R, Munro N, Joosten A.
PMID: 31611828
Front Psychol. 2019 Aug 27;10:1960. doi: 10.3389/fpsyg.2019.01960. eCollection 2019.

PURPOSE: This randomized controlled trial evaluated the effectiveness of a play-based pragmatic language intervention for children with autism.METHODS: A sample of 71 children with autism were randomized to an intervention-first group (RESULTS: POM-2 gains were greatest for intervention-first participants...

Transition from early intervention program to primary school in children with autism spectrum disorder.

World journal of clinical pediatrics

Eapen V, Grove R, Aylward E, Joosten AV, Miller SI, Van Der Watt G, Fordyce K, Dissanayake C, Maya J, Tucker M, DeBlasio A.
PMID: 29259892
World J Clin Pediatr. 2017 Nov 08;6(4):169-175. doi: 10.5409/wjcp.v6.i4.169. eCollection 2017 Nov 08.

AIM: To evaluate the characteristics that are associated with successful transition to school outcomes in preschool aged children with autism.METHODS: Twenty-one participants transitioning from an early intervention program were assessed at two time points; at the end of their...

Procedure-Specific Pain Intensity Four Days After Day Surgery and the Relationship with Preoperative Pain: A Prospective Cohort Study.

Anesthesiology and pain medicine

Vrancken D, Theunissen M, Joosten EA, Fiddelers AAA, Hoofwijk DMN, Buhre WFFA, Gramke HF, Stessel BOR.
PMID: 30719413
Anesth Pain Med. 2018 Nov 17;8(6):e81366. doi: 10.5812/aapm.81366. eCollection 2018 Dec.

BACKGROUND: Identification of painful procedures is essential for the development of procedure-specific pain-treatment schedules. The aim of this study was firstly, to analyze the prevalence of acute postsurgical pain (APSP) after various types of day surgery on the fourth...

100 years of the Bacillus Calmette-Guérin vaccine.

Vaccine

Bettencourt PJG, Joosten SA, Lindestam Arlehamn CS, Behr MA, Locht C, Neyrolles O.
PMID: 34823911
Vaccine. 2021 Dec 08;39(50):7221-7222. doi: 10.1016/j.vaccine.2021.11.038. Epub 2021 Nov 22.

No abstract available.

Early-life exposure to selective serotonin reuptake inhibitors: long-term effects on pain and affective comorbidities.

The European journal of neuroscience

Baudat M, de Kort AR, van den Hove DLA, Joosten EAJ.
PMID: 34841582
Eur J Neurosci. 2021 Nov 29; doi: 10.1111/ejn.15544. Epub 2021 Nov 29.

A growing body of evidence indicate that early-life exposure to selective serotonin reuptake inhibitor has long-term consequences on the offspring's pain in addition to affective disorders like anxiety disorder and major depression. Serotonin, beside its role in regulating pain...

Protective immune response mediated by neutrophils in experimental visceral leishmaniasis is enhanced by IL-32γ.

Cellular immunology

Gomes RS, Silva MVT, Oliveira MAP, Joosten LAB, Ribeiro-Dias F.
PMID: 34784560
Cell Immunol. 2021 Nov 10;371:104449. doi: 10.1016/j.cellimm.2021.104449. Epub 2021 Nov 10.

Neutrophils are important cells in protection against microbial infections including visceral leishmaniasis (VL). It is well known that IL-32γ increases the protective T helper 17 cell mediated immune response against Leishmania infantum. Thus, in this study we evaluated whether...

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease.

Blood

Molteni R, Biavasco R, Stefanoni D, Nemkov T, Domínguez-Andrés J, Arts RJ, Merelli I, Mazza D, Zambrano S, Panigada M, Cantoni E, Tengesdal IW, Maksud P, Piras F, Cesana D, Cassina L, Distefano G, Loffreda A, Gnani D, De Luca G, Tomelleri A, Campochiaro C, Joosten LAB, Dinarello CA, Kajaste-Rudnitski A, Haroche J, Cardaci S, Cenci S, Dagna L, Doglioni C, Ferrarini M, Ferrero E, Boletta A, D'Alessandro A, Montini E, Netea MG, Cavalli G.
PMID: 34077954
Blood. 2021 Oct 28;138(17):1554-1569. doi: 10.1182/blood.2020009594.

Trained immunity (TI) is a proinflammatory program induced in monocyte/macrophages upon sensing of specific pathogens and is characterized by immunometabolic and epigenetic changes that enhance cytokine production. Maladaptive activation of TI (ie, in the absence of infection) may result...

Showing 1 to 12 of 176 entries