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Showing 1 to 12 of 438 entries
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Characterization of infiltrating lymphocytes in human benign and malignant prostate tissue.

Oncotarget

Rådestad E, Egevad L, Jorns C, Mattsson J, Sundberg B, Nava S, Ericzon BG, Henningsohn L, Levitsky V, Uhlin M.
PMID: 28947968
Oncotarget. 2017 Jul 24;8(36):60257-60269. doi: 10.18632/oncotarget.19528. eCollection 2017 Sep 01.

Immune checkpoint blockade has shown promising results in numerous cancer types. However, in prostate cancer (PC), absent or limited responses have been reported. To investigate further, we compared the phenotype of infiltrating T-cells isolated from prostate tissue from patients...

Coherent structural dynamics of a prototypical charge-density-wave-to-metal transition.

Physical review letters

Huber T, Mariager SO, Ferrer A, Schäfer H, Johnson JA, Grübel S, Lübcke A, Huber L, Kubacka T, Dornes C, Laulhe C, Ravy S, Ingold G, Beaud P, Demsar J, Johnson SL.
PMID: 25062214
Phys Rev Lett. 2014 Jul 11;113(2):026401. doi: 10.1103/PhysRevLett.113.026401. Epub 2014 Jul 11.

Using femtosecond time-resolved x-ray diffraction, we directly monitor the coherent lattice dynamics through an ultrafast charge-density-wave-to-metal transition in the prototypical Peierls system K(0.3)MoO(3) over a wide range of relevant excitation fluences. While in the low fluence regime we directly...

Chronic Diarrhea in L-Amino Acid Decarboxylase (AADC) Deficiency: A Prominent Clinical Finding Among a Series of Ten French Patients.

JIMD reports

Spitz MA, Nguyen MA, Roche S, Heron B, Milh M, de Lonlay P, Lion-François L, Testard H, Napuri S, Barth M, Fournier-Favre S, Christa L, Vianey-Saban C, Corne C, Roubertie A.
PMID: 27147232
JIMD Rep. 2017;31:85-93. doi: 10.1007/8904_2016_550. Epub 2016 May 05.

Aromatic L-amino acid decarboxylase (AADC) deficiency is an autosomal recessive inborn error of metabolism, affecting catecholamines and serotonin biosynthesis. Cardinal signs consist in psychomotor delay, hypotonia, oculogyric crises, dystonia, and extraneurological symptoms.PATIENTS AND METHODS: We present a retrospective descriptive...

Biobanking from the patient perspective.

Research involvement and engagement

Mitchell D, Geissler J, Parry-Jones A, Keulen H, Schmitt DC, Vavassori R, Matharoo-Ball B.
PMID: 29062493
Res Involv Engagem. 2015 Jun 25;1:4. doi: 10.1186/s40900-015-0001-z. eCollection 2015.

PLAIN ENGLISH SUMMARY: Biobanks are collections of donations of biological material (DNA, cells, tissue etc.) and related data which are very valuable for research into human diseases. A variety of biobanks exist for example within hospitals, research institutes, pharmaceutical...

Development of a communication aid for explaining hypertrophic cardiomyopathy genetic test results.

Pilot and feasibility studies

Smagarinsky Y, Burns C, Spinks C, Semsarian C, Ingles J.
PMID: 29152326
Pilot Feasibility Stud. 2017 Nov 09;3:53. doi: 10.1186/s40814-017-0205-0. eCollection 2017.

BACKGROUND: Large gene panels are now commonplace for hypertrophic cardiomyopathy (HCM), increasing the yield of uncertain genetic findings. Few resources exist which aim to facilitate communication of HCM genetic test results. We sought to develop, pilot, and refine a...

Nickel-catalyzed reductive arylation of activated alkynes with aryl iodides.

Tetrahedron letters

Dorn SC, Olsen AK, Kelemen RE, Shrestha R, Weix DJ.
PMID: 26028781
Tetrahedron Lett. 2015 Jun 03;56(23):3365-3367. doi: 10.1016/j.tetlet.2015.02.120.

The direct, regioselective, and stereoselective arylation of activated alkynes with aryl iodides using a nickel catalyst and manganese reductant is described. The reaction conditions are mild (40 °C in MeOH, no acid or base) and an intermediate organomanganese reagent...

Perceived Immune Status and Sleep: A Survey among Dutch Students.

Sleep disorders

Donners AA, Tromp MD, Garssen J, Roth T, Verster JC.
PMID: 26448877
Sleep Disord. 2015;2015:721607. doi: 10.1155/2015/721607. Epub 2015 Sep 10.

Reduced immune functioning may have a negative impact on sleep and health, and vice versa. A survey among Dutch young adults (18-35 years old) was administered to collect information on perception of reduced immunity and its relationship to sleep...

Progress in infrared photodetectors since 2000.

Sensors (Basel, Switzerland)

Downs C, Vandervelde TE.
PMID: 23591965
Sensors (Basel). 2013 Apr 16;13(4):5054-98. doi: 10.3390/s130405054.

The first decade of the 21st-century has seen a rapid development in infrared photodetector technology. At the end of the last millennium there were two dominant IR systems, InSb- and HgCdTe-based detectors, which were well developed and available in...

Neuromuscular electrical stimulation leads to physiological gains enhancing postural balance in the pre-frail elderly.

Physiological reports

Mignardot JB, Deschamps T, Le Goff CG, Roumier FX, Duclay J, Martin A, Sixt M, Pousson M, Cornu C.
PMID: 26229006
Physiol Rep. 2015 Jul;3(7). doi: 10.14814/phy2.12471.

Physiological aging leads to a progressive weakening of muscles and tendons, thereby disturbing the ability to control postural balance and consequently increasing exposure to the risks of falls. Here, we introduce a simple and easy-to-use neuromuscular electrical stimulation (NMES)...

Alaskan interlude.

Journal of the American Medical Women's Association

BURNS C.
PMID: 13233065
J Am Med Womens Assoc. 1955 Jan;10(1):18-9.

No abstract available.

The mental deficiency services; an analysis of existing policy and the community's requirements.

The New Zealand medical journal

BURNS C.
PMID: 13644685
N Z Med J. 1959 Feb;58(323):83-109.

No abstract available.

Identification of inorganic improvised explosive devices by analysis of postblast residues using portable capillary electrophoresis instrumentation and indirect photometric detection with a light-emitting diode.

Analytical chemistry

Hutchinson JP, Evenhuis CJ, Johns C, Kazarian AA, Breadmore MC, Macka M, Hilder EF, Guijt RM, Dicinoski GW, Haddad PR.
PMID: 17705451
Anal Chem. 2007 Sep 15;79(18):7005-13. doi: 10.1021/ac0708792. Epub 2007 Aug 18.

A commercial portable capillary electrophoresis (CE) instrument has been used to separate inorganic anions and cations found in postblast residues from improvised explosive devices (IEDs) of the type used frequently in terrorism attacks. The purpose of this analysis was...

Showing 1 to 12 of 438 entries