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Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale.

Engineering in life sciences

Kaiser SC, Werner S, Jossen V, Kraume M, Eibl D.
PMID: 28579937
Eng Life Sci. 2017 May;17(5):500-511. doi: 10.1002/elsc.201600096. Epub 2016 Nov 25.

Power input is an important engineering and scale-up/down criterion in stirred bioreactors. However, reliably measuring power input in laboratory-scale systems is still challenging. Even though torque measurements have proven to be suitable in pilot scale systems, sensor accuracy, resolution,...

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Kaiser SC, Werner S, Jossen V, et al. Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale. Eng Life Sci. 2016;17(5):500-511doi: 10.1002/elsc.201600096.
Kaiser, S. C., Werner, S., Jossen, V., Kraume, M., & Eibl, D. (2017). Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale. Engineering in life sciences, 17(5), 500-511. https://doi.org/10.1002/elsc.201600096
Kaiser, Stephan C, et al. "Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale." Engineering in life sciences vol. 17,5 (2017): 500-511. doi: https://doi.org/10.1002/elsc.201600096
Kaiser SC, Werner S, Jossen V, Kraume M, Eibl D. Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale. Eng Life Sci. 2017 May;17(5):500-511. doi: 10.1002/elsc.201600096. Epub 2016 Nov 25. PMID: 28579937; PMCID: PMC5434943.
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Intracorporeal knotting of a femoral nerve catheter.

GMS Interdisciplinary plastic and reconstructive surgery DGPW

Ghanem M, Schnoor J, Wiegel M, Josten C, Reske AW.
PMID: 26504733
GMS Interdiscip Plast Reconstr Surg DGPW. 2015 Jan 28;4:Doc04. doi: 10.3205/iprs000063. eCollection 2015.

Peripheral nerve catheters are effective and well-established tools to provide postoperative analgesia to patients undergoing orthopedic surgery. The performance of these techniques is usually considered safe. However, placement of nerve catheters may be associated with a considerable number of...

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Ghanem M, Schnoor J, Wiegel M, et al. Intracorporeal knotting of a femoral nerve catheter. GMS Interdiscip Plast Reconstr Surg DGPW. 2015;4:Doc04doi: 10.3205/iprs000063.
Ghanem, M., Schnoor, J., Wiegel, M., Josten, C., & Reske, A. W. (2015). Intracorporeal knotting of a femoral nerve catheter. GMS Interdisciplinary plastic and reconstructive surgery DGPW, 4Doc04. https://doi.org/10.3205/iprs000063
Ghanem, Mohamed, et al. "Intracorporeal knotting of a femoral nerve catheter." GMS Interdisciplinary plastic and reconstructive surgery DGPW vol. 4 (2015): Doc04. doi: https://doi.org/10.3205/iprs000063
Ghanem M, Schnoor J, Wiegel M, Josten C, Reske AW. Intracorporeal knotting of a femoral nerve catheter. GMS Interdiscip Plast Reconstr Surg DGPW. 2015 Jan 28;4:Doc04. doi: 10.3205/iprs000063. eCollection 2015. PMID: 26504733; PMCID: PMC4604746.
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Management strategies in hospitals: scenario planning.

GMS Interdisciplinary plastic and reconstructive surgery DGPW

Ghanem M, Schnoor J, Heyde CE, Kuwatsch S, Bohn M, Josten C.
PMID: 26504735
GMS Interdiscip Plast Reconstr Surg DGPW. 2015 Jun 22;4:Doc06. doi: 10.3205/iprs000065. eCollection 2015.

BACKGROUND: Instead of waiting for challenges to confront hospital management, doctors and managers should act in advance to optimize and sustain value-based health. This work highlights the importance of scenario planning in hospitals, proposes an elaborated definition of the...

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Ghanem M, Schnoor J, Heyde CE, et al. Management strategies in hospitals: scenario planning. GMS Interdiscip Plast Reconstr Surg DGPW. 2015;4:Doc06doi: 10.3205/iprs000065.
Ghanem, M., Schnoor, J., Heyde, C. E., Kuwatsch, S., Bohn, M., & Josten, C. (2015). Management strategies in hospitals: scenario planning. GMS Interdisciplinary plastic and reconstructive surgery DGPW, 4Doc06. https://doi.org/10.3205/iprs000065
Ghanem, Mohamed, et al. "Management strategies in hospitals: scenario planning." GMS Interdisciplinary plastic and reconstructive surgery DGPW vol. 4 (2015): Doc06. doi: https://doi.org/10.3205/iprs000065
Ghanem M, Schnoor J, Heyde CE, Kuwatsch S, Bohn M, Josten C. Management strategies in hospitals: scenario planning. GMS Interdiscip Plast Reconstr Surg DGPW. 2015 Jun 22;4:Doc06. doi: 10.3205/iprs000065. eCollection 2015. PMID: 26504735; PMCID: PMC4604740.
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The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'.

The journal of trauma and acute care surgery

Pape HC, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, Lichte P, Josten C, Bouillon B, Schmucker U, Stahel P, Giannoudis P, Balogh Z.
PMID: 25494433
J Trauma Acute Care Surg. 2014 Nov;77(5):780-786. doi: 10.1097/TA.0000000000000453.

BACKGROUND: The nomenclature for patients with multiple injuries with high mortality rates is highly variable, and there is a lack of a uniform definition of the term polytrauma. A consensus process was therefore initiated by a panel of international...

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Pape HC, Lefering R, Butcher N, et al. The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'. J Trauma Acute Care Surg. 2014;77(5):780-786doi: 10.1097/TA.0000000000000453.
Pape, H. C., Lefering, R., Butcher, N., Peitzman, A., Leenen, L., Marzi, I., Lichte, P., Josten, C., Bouillon, B., Schmucker, U., Stahel, P., Giannoudis, P., & Balogh, Z. (2014). The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'. The journal of trauma and acute care surgery, 77(5), 780-786. https://doi.org/10.1097/TA.0000000000000453
Pape, Hans-Christoph, et al. "The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'." The journal of trauma and acute care surgery vol. 77,5 (2014): 780-786. doi: https://doi.org/10.1097/TA.0000000000000453
Pape HC, Lefering R, Butcher N, Peitzman A, Leenen L, Marzi I, Lichte P, Josten C, Bouillon B, Schmucker U, Stahel P, Giannoudis P, Balogh Z. The definition of polytrauma revisited: An international consensus process and proposal of the new 'Berlin definition'. J Trauma Acute Care Surg. 2014 Nov;77(5):780-786. doi: 10.1097/TA.0000000000000453. PMID: 25494433.
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ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches.

Pharmacogenomics and personalized medicine

Cleophas MC, Joosten LA, Stamp LK, Dalbeth N, Woodward OM, Merriman TR.
PMID: 28461764
Pharmgenomics Pers Med. 2017 Apr 20;10:129-142. doi: 10.2147/PGPM.S105854. eCollection 2017.

As a result of the association of a common polymorphism (

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Cleophas MC, Joosten LA, Stamp LK, et al. ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches. Pharmgenomics Pers Med. 2017;10:129-142doi: 10.2147/PGPM.S105854.
Cleophas, M. C., Joosten, L. A., Stamp, L. K., Dalbeth, N., Woodward, O. M., & Merriman, T. R. (2017). ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches. Pharmacogenomics and personalized medicine, 10129-142. https://doi.org/10.2147/PGPM.S105854
Cleophas, M C, et al. "ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches." Pharmacogenomics and personalized medicine vol. 10 (2017): 129-142. doi: https://doi.org/10.2147/PGPM.S105854
Cleophas MC, Joosten LA, Stamp LK, Dalbeth N, Woodward OM, Merriman TR. ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches. Pharmgenomics Pers Med. 2017 Apr 20;10:129-142. doi: 10.2147/PGPM.S105854. eCollection 2017. PMID: 28461764; PMCID: PMC5404803.
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Severe cardiac trauma or myocardial ischemia? Pitfalls of polytrauma treatment in patients with ST-elevation after blunt chest trauma.

Annals of medicine and surgery (2012)

Özkurtul O, Höch A, Reske A, Hädrich C, Josten C, Böhme J.
PMID: 26288729
Ann Med Surg (Lond). 2015 Aug 04;4(3):254-9. doi: 10.1016/j.amsu.2015.07.019. eCollection 2015 Sep.

INTRODUCTION: Thoracic injuries are the third most common injuries in polytrauma patients. The mechanism of injury and the clinical presentation are crucially important for adequate emergency treatment.PRESENTATION OF CASE: Here we present a case of a 37-year-old male who...

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Özkurtul O, Höch A, Reske A, et al. Severe cardiac trauma or myocardial ischemia? Pitfalls of polytrauma treatment in patients with ST-elevation after blunt chest trauma. Ann Med Surg (Lond). 2015;4(3):254-9doi: 10.1016/j.amsu.2015.07.019.
Özkurtul, O., Höch, A., Reske, A., Hädrich, C., Josten, C., & Böhme, J. (2015). Severe cardiac trauma or myocardial ischemia? Pitfalls of polytrauma treatment in patients with ST-elevation after blunt chest trauma. Annals of medicine and surgery (2012), 4(3), 254-9. https://doi.org/10.1016/j.amsu.2015.07.019
Özkurtul, Orkun, et al. "Severe cardiac trauma or myocardial ischemia? Pitfalls of polytrauma treatment in patients with ST-elevation after blunt chest trauma." Annals of medicine and surgery (2012) vol. 4,3 (2015): 254-9. doi: https://doi.org/10.1016/j.amsu.2015.07.019
Özkurtul O, Höch A, Reske A, Hädrich C, Josten C, Böhme J. Severe cardiac trauma or myocardial ischemia? Pitfalls of polytrauma treatment in patients with ST-elevation after blunt chest trauma. Ann Med Surg (Lond). 2015 Aug 04;4(3):254-9. doi: 10.1016/j.amsu.2015.07.019. eCollection 2015 Sep. PMID: 26288729; PMCID: PMC4539162.
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An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency?.

Case reports in orthopedics

Höch A, Pieroh P, Dehghani F, Josten C, Böhme J.
PMID: 26904337
Case Rep Orthop. 2016;2016:9250938. doi: 10.1155/2016/9250938. Epub 2016 Jan 20.

Glucocorticoids are well known for altering bone structure and elevating fracture risk. Nevertheless, there are very few reports on pelvic ring fractures, compared to other bones, especially with a predominantly ligamentous insufficiency, resulting in a rotationally unstable pelvic girdle....

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Höch A, Pieroh P, Dehghani F, et al. An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency?. Case Rep Orthop. 2016;2016:9250938doi: 10.1155/2016/9250938.
Höch, A., Pieroh, P., Dehghani, F., Josten, C., & Böhme, J. (2016). An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency?. Case reports in orthopedics, 20169250938. https://doi.org/10.1155/2016/9250938
Höch, Andreas, et al. "An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency?." Case reports in orthopedics vol. 2016 (2016): 9250938. doi: https://doi.org/10.1155/2016/9250938
Höch A, Pieroh P, Dehghani F, Josten C, Böhme J. An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency?. Case Rep Orthop. 2016;2016:9250938. doi: 10.1155/2016/9250938. Epub 2016 Jan 20. PMID: 26904337; PMCID: PMC4745920.
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Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis.

Frontiers in microbiology

Rosentul DC, Delsing CE, Jaeger M, Plantinga TS, Oosting M, Costantini I, Venselaar H, Joosten LA, van der Meer JW, Dupont B, Kullberg BJ, Sobel JD, Netea MG.
PMID: 25295030
Front Microbiol. 2014 Sep 23;5:483. doi: 10.3389/fmicb.2014.00483. eCollection 2014.

OBJECTIVE: Approximately 5% of women suffer from recurrent vulvovaginal candidiasis (RVVC). It has been hypothesized that genetic factors play an important role in the susceptibility to RVVC. The aim of this study was to assess the effect of genetic...

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Rosentul DC, Delsing CE, Jaeger M, et al. Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis. Front Microbiol. 2014;5:483doi: 10.3389/fmicb.2014.00483.
Rosentul, D. C., Delsing, C. E., Jaeger, M., Plantinga, T. S., Oosting, M., Costantini, I., Venselaar, H., Joosten, L. A., van der Meer, J. W., Dupont, B., Kullberg, B. J., Sobel, J. D., & Netea, M. G. (2014). Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis. Frontiers in microbiology, 5483. https://doi.org/10.3389/fmicb.2014.00483
Rosentul, Diana C, et al. "Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis." Frontiers in microbiology vol. 5 (2014): 483. doi: https://doi.org/10.3389/fmicb.2014.00483
Rosentul DC, Delsing CE, Jaeger M, Plantinga TS, Oosting M, Costantini I, Venselaar H, Joosten LA, van der Meer JW, Dupont B, Kullberg BJ, Sobel JD, Netea MG. Gene polymorphisms in pattern recognition receptors and susceptibility to idiopathic recurrent vulvovaginal candidiasis. Front Microbiol. 2014 Sep 23;5:483. doi: 10.3389/fmicb.2014.00483. eCollection 2014. PMID: 25295030; PMCID: PMC4172055.
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Hydrothermal synthesis and characterization of the new layered fluorogallophosphate mu-23.

Chemistry (Weinheim an der Bergstrasse, Germany)

Josien L, Simon-Masseron A, Gramlich V, Patarin J.
PMID: 11933089
Chemistry. 2002 Apr 02;8(7):1614-20. doi: 10.1002/1521-3765(20020402)8:7<1614::aid-chem1614>3.0.co;2-t.

Mu-23, [(C(6)H(15)N(2))(C(6)H(16)N(2))Ga(5)F(6)(H(2)O)(2)(PO(4))(4)] x 4 H(2)O, the first layered fluorinated gallophosphate with a Ga/P molar ratio of 5:4, was obtained in the presence of fluoride ions with 1,4-dimethylpiperazine as an organic template. It crystallizes in the triclinic space group P1...

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Josien L, Simon-Masseron A, Gramlich V, et al. Hydrothermal synthesis and characterization of the new layered fluorogallophosphate mu-23. Chemistry. 2002;8(7):1614-20doi: 10.1002/1521-3765(20020402)8:7<1614::aid-chem1614>3.0.co;2-t.
Josien, L., Simon-Masseron, A., Gramlich, V., & Patarin, J. (2002). Hydrothermal synthesis and characterization of the new layered fluorogallophosphate mu-23. Chemistry (Weinheim an der Bergstrasse, Germany), 8(7), 1614-20. https://doi.org/10.1002/1521-3765(20020402)8:7<1614::aid-chem1614>3.0.co;2-t
Josien, Ludovic, et al. "Hydrothermal synthesis and characterization of the new layered fluorogallophosphate mu-23." Chemistry (Weinheim an der Bergstrasse, Germany) vol. 8,7 (2002): 1614-20. doi: https://doi.org/10.1002/1521-3765(20020402)8:7<1614::aid-chem1614>3.0.co;2-t
Josien L, Simon-Masseron A, Gramlich V, Patarin J. Hydrothermal synthesis and characterization of the new layered fluorogallophosphate mu-23. Chemistry. 2002 Apr 02;8(7):1614-20. doi: 10.1002/1521-3765(20020402)8:7<1614::aid-chem1614>3.0.co;2-t. PMID: 11933089.
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Lensless focusing with an array of phase-adjusted optical fibers.

Applied optics

Josten G, Weber HP, Luethy W.
PMID: 20556012
Appl Opt. 1989 Dec 01;28(23):5133-7. doi: 10.1364/AO.28.005133.

A bundle of monomode fibers can be used for transmission of coherent radiation at power levels beyond the damage threshold of an individual fiber. The coherence at the bundle output can be reestablished by proper correction of the phases...

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Josten G, Weber HP, Luethy W. Lensless focusing with an array of phase-adjusted optical fibers. Appl Opt. 1989;28(23):5133-7doi: 10.1364/AO.28.005133.
Josten, G., Weber, H. P., & Luethy, W. (1989). Lensless focusing with an array of phase-adjusted optical fibers. Applied optics, 28(23), 5133-7. https://doi.org/10.1364/AO.28.005133
Josten, G, et al. "Lensless focusing with an array of phase-adjusted optical fibers." Applied optics vol. 28,23 (1989): 5133-7. doi: https://doi.org/10.1364/AO.28.005133
Josten G, Weber HP, Luethy W. Lensless focusing with an array of phase-adjusted optical fibers. Appl Opt. 1989 Dec 01;28(23):5133-7. doi: 10.1364/AO.28.005133. PMID: 20556012.
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Defensive properties of pyrrolizidine alkaloids against microorganisms.

Phytochemistry reviews : proceedings of the Phytochemical Society of Europe

Joosten L, van Veen JA.
PMID: 21475390
Phytochem Rev. 2011 Mar;10(1):127-136. doi: 10.1007/s11101-010-9204-y. Epub 2010 Nov 23.

The understanding of the selection factors that drive chemical diversification of secondary metabolites of constitutive defence systems in plants, such as pyrrolizidine alkaloids (PAs), is still incomplete. Historically, plants always have been confronted with microorganisms. Long before herbivores existed...

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Joosten L, van Veen JA. Defensive properties of pyrrolizidine alkaloids against microorganisms. Phytochem Rev. 2010;10(1):127-136doi: 10.1007/s11101-010-9204-y.
Joosten, L., & van Veen, J. A. (2011). Defensive properties of pyrrolizidine alkaloids against microorganisms. Phytochemistry reviews : proceedings of the Phytochemical Society of Europe, 10(1), 127-136. https://doi.org/10.1007/s11101-010-9204-y
Joosten, Lotte, and van Veen, Johannes A. "Defensive properties of pyrrolizidine alkaloids against microorganisms." Phytochemistry reviews : proceedings of the Phytochemical Society of Europe vol. 10,1 (2011): 127-136. doi: https://doi.org/10.1007/s11101-010-9204-y
Joosten L, van Veen JA. Defensive properties of pyrrolizidine alkaloids against microorganisms. Phytochem Rev. 2011 Mar;10(1):127-136. doi: 10.1007/s11101-010-9204-y. Epub 2010 Nov 23. PMID: 21475390; PMCID: PMC3047671.
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Missed foot fractures in polytrauma patients: a retrospective cohort study.

Patient safety in surgery

Ahrberg AB, Leimcke B, Tiemann AH, Josten C, Fakler JK.
PMID: 24568599
Patient Saf Surg. 2014 Feb 25;8(1):10. doi: 10.1186/1754-9493-8-10.

BACKGROUND: Missed foot fractures are a known problem in the care of the traumatized patient. They do not usually have an influence on the survival, but on the long-term result and the quality of the patient's life. The aim...

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Ahrberg AB, Leimcke B, Tiemann AH, et al. Missed foot fractures in polytrauma patients: a retrospective cohort study. Patient Saf Surg. 2014;8(1):10doi: 10.1186/1754-9493-8-10.
Ahrberg, A. B., Leimcke, B., Tiemann, A. H., Josten, C., & Fakler, J. K. (2014). Missed foot fractures in polytrauma patients: a retrospective cohort study. Patient safety in surgery, 8(1), 10. https://doi.org/10.1186/1754-9493-8-10
Ahrberg, Annette B, et al. "Missed foot fractures in polytrauma patients: a retrospective cohort study." Patient safety in surgery vol. 8,1 (2014): 10. doi: https://doi.org/10.1186/1754-9493-8-10
Ahrberg AB, Leimcke B, Tiemann AH, Josten C, Fakler JK. Missed foot fractures in polytrauma patients: a retrospective cohort study. Patient Saf Surg. 2014 Feb 25;8(1):10. doi: 10.1186/1754-9493-8-10. PMID: 24568599; PMCID: PMC3944986.
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