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Showing 1 to 12 of 15 entries
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Cell Surface Protein mRNAs Show Differential Transcription in Pyramidal and Fast-Spiking Cells as Revealed by Single-Cell Sequencing.

Cerebral cortex (New York, N.Y. : 1991)

Ravasz L, Kékesi KA, Mittli D, Todorov MI, Borhegyi Z, Ercsey-Ravasz M, Tyukodi B, Wang J, Bártfai T, Eberwine J, Juhász G.
PMID: 32710103
Cereb Cortex. 2021 Jan 05;31(2):731-745. doi: 10.1093/cercor/bhaa195.

The prefrontal cortex (PFC) plays a key role in higher order cognitive functions and psychiatric disorders such as autism, schizophrenia, and depression. In the PFC, the two major classes of neurons are the glutamatergic pyramidal (Pyr) cells and the...

[Current status and possibilities of distant education in medicine].

Orvosi hetilap

Kékes E.
PMID: 10624108
Orv Hetil. 1999 Oct 24;140(43):2379-84.

Author analyses the concept and methods of distance education. The definition of distance education consist of geographic separation of the learner and the teacher, the high level of educational organisation, the use of modern technology for communication with interactivity....

Wisket rat model of schizophrenia: Impaired motivation and, altered brain structure, but no anhedonia.

Physiology & behavior

Büki A, Bohár Z, Kekesi G, Vécsei L, Horvath G.
PMID: 34800492
Physiol Behav. 2021 Nov 17;244:113651. doi: 10.1016/j.physbeh.2021.113651. Epub 2021 Nov 17.

It is well-known that the poor cognition in schizophrenia is strongly linked to negative symptoms, including motivational deficit, which due to, at least partially, anhedonia. The goal of this study was to explore whether the schizophrenia-like Wisket animals with...

Wisket rat model of schizophrenia: Impaired motivation and, altered brain structure, but no anhedonia.

Physiology & behavior

Büki A, Bohár Z, Kekesi G, Vécsei L, Horvath G.
PMID: 34800492
Physiol Behav. 2021 Nov 17;244:113651. doi: 10.1016/j.physbeh.2021.113651. Epub 2021 Nov 17.

It is well-known that the poor cognition in schizophrenia is strongly linked to negative symptoms, including motivational deficit, which due to, at least partially, anhedonia. The goal of this study was to explore whether the schizophrenia-like Wisket animals with...

Method for Prolonged Incubation of Brain Slices.

Bio-protocol

Kékesi O, Buskila Y.
PMID: 33659354
Bio Protoc. 2020 Jul 20;10(14):e3683. doi: 10.21769/BioProtoc.3683. eCollection 2020 Jul 20.

Slices of neuronal tissue maintain a high degree of topographical and functional properties of neurons and glia and therefore are extensively used for measurements of neuronal activity at the molecular, cellular and network levels. However, the lifespan of slice...

Recurrent seizure-like events are associated with coupled astroglial synchronization.

Frontiers in cellular neuroscience

Kékesi O, Ioja E, Szabó Z, Kardos J, Héja L.
PMID: 26150770
Front Cell Neurosci. 2015 Jun 18;9:215. doi: 10.3389/fncel.2015.00215. eCollection 2015.

Increasing evidence suggest that astrocytes significantly modulate neuronal function at the level of the tripartite synapse both in physiological and pathophysiological conditions. The global control of the astrocytic syncytium over neuronal networks, however, is still less recognized. Here we...

Hemodynamic Effects of the Light Stabilizer Tinuvin 770 in Dogs .

The open medicinal chemistry journal

Krepuska M, Hubay M, Zima E, Kovacs A, Kekesi V, Kalasz H, Szilagyi B, Merkely B, Sotonyi P.
PMID: 30288180
Open Med Chem J. 2018 Aug 31;12:88-97. doi: 10.2174/1874104501812010088. eCollection 2018.

INTRODUCTION: Tinuvin 770 [bis(2,2,6,6-tetramethyl-4-piperidinyl) sebacate, Ciba-Geigy, Basel, Switzerland] is a UV light stabilizer that is a component of many plastic materials used world-wide in the medical and food industries. We report on the acute hemodynamic effects of Tinuvin 770...

Wisket rat model of schizophrenia: Impaired motivation and, altered brain structure, but no anhedonia.

Physiology & behavior

Büki A, Bohár Z, Kekesi G, Vécsei L, Horvath G.
PMID: 34800492
Physiol Behav. 2022 Feb 01;244:113651. doi: 10.1016/j.physbeh.2021.113651. Epub 2021 Nov 17.

It is well-known that the poor cognition in schizophrenia is strongly linked to negative symptoms, including motivational deficit, which due to, at least partially, anhedonia. The goal of this study was to explore whether the schizophrenia-like Wisket animals with...

The Single-Cell Transcriptomic Analysis of Prefrontal Pyramidal Cells and Interneurons Reveals the Neuronal Expression of Genes Encoding Antimicrobial Peptides and Immune Proteins.

Frontiers in immunology

Mittli D, Tukacs V, Micsonai A, Ravasz L, Kardos J, Juhász G, Kékesi KA.
PMID: 34759929
Front Immunol. 2021 Oct 25;12:749433. doi: 10.3389/fimmu.2021.749433. eCollection 2021.

The investigation of the molecular background of direct communication of neurons and immune cells in the brain is an important issue for understanding physiological and pathological processes in the nervous system. Direct contacts between brain-infiltrating immune cells and neurons,...

The Effect of Sleep Deprivation and Subsequent Recovery Period on the Synaptic Proteome of Rat Cerebral Cortex.

Molecular neurobiology

Gulyássy P, Todorov-Völgyi K, Tóth V, Györffy BA, Puska G, Simor A, Juhász G, Drahos L, Kékesi KA.
PMID: 34988919
Mol Neurobiol. 2022 Jan 05; doi: 10.1007/s12035-021-02699-x. Epub 2022 Jan 05.

Sleep deprivation (SD) is commonplace in the modern way of life and has a substantial social, medical, and human cost. Sleep deprivation induces cognitive impairment such as loss of executive attention, working memory decline, poor emotion regulation, increased reaction...

Body structural and cellular aging of women with low socioeconomic status in Hungary: A pilot study.

American journal of human biology : the official journal of the Human Biology Council

Annar D, Feher P, Madarasi A, Mascie-Taylor N, Kekesi A, Kalabiska I, Muzsnai A, Zsakai A.
PMID: 34346536
Am J Hum Biol. 2021 Aug 04;e23662. doi: 10.1002/ajhb.23662. Epub 2021 Aug 04.

OBJECTIVES: The health status of an individual is determined not only by their genetic background but also by their physical environment, social environment and access and use of the health care system. The Roma are one of the largest...

Results of Complex Immunopharmacological Analysis of the Mechanisms of Action of Bioregulation Agents.

Bulletin of experimental biology and medicine

Kazimirskii АN, Salmasi ZМ, Poryadin GV, Kukes IV.
PMID: 34792717
Bull Exp Biol Med. 2021 Nov;172(1):38-41. doi: 10.1007/s10517-021-05326-w. Epub 2021 Nov 18.

Elucidation of the pharmacodynamic mechanisms of drugs capable of potentiating the effects of non-steroidal anti-inflammatory drugs is an important task. In this in vitro study, the ability of Traumeel S to influence the innate and acquired immunity was evaluated....

Showing 1 to 12 of 15 entries