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Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines.

Scientia pharmaceutica

Kovalenko SI, Antypenko LM, Bilyi AK, Kholodnyak SV, Karpenko OV, Antypenko OM, Mykhaylova NS, Los TI, Kolomoets OS.
PMID: 23833709
Sci Pharm. 2013 Apr-Jun;81(2):359-91. doi: 10.3797/scipharm.1211-08. Epub 2012 Dec 23.

The combinatorial library of novel potential anticancer agents, namely, 2-(alkyl-, alkaryl-, aryl-, hetaryl-)[1,2,4]triazolo[1,5-c]quinazolines, was synthesized by the heterocyclization of the alkyl-, alkaryl-, aryl-, hetarylcarboxylic acid (3H-quinazoline-4-ylidene)hydrazides by oxidative heterocyclization of the 4-(arylidenehydrazino)quinazolines using bromine, and by the heterocyclization of...

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Kovalenko SI, Antypenko LM, Bilyi AK, et al. Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines. Sci Pharm. 2012;81(2):359-91doi: 10.3797/scipharm.1211-08.
Kovalenko, S. I., Antypenko, L. M., Bilyi, A. K., Kholodnyak, S. V., Karpenko, O. V., Antypenko, O. M., Mykhaylova, N. S., Los, T. I., & Kolomoets, O. S. (2013). Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines. Scientia pharmaceutica, 81(2), 359-91. https://doi.org/10.3797/scipharm.1211-08
Kovalenko, Sergiy I, et al. "Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines." Scientia pharmaceutica vol. 81,2 (2013): 359-91. doi: https://doi.org/10.3797/scipharm.1211-08
Kovalenko SI, Antypenko LM, Bilyi AK, Kholodnyak SV, Karpenko OV, Antypenko OM, Mykhaylova NS, Los TI, Kolomoets OS. Synthesis and Anticancer Activity of 2-(Alkyl-, Alkaryl-, Aryl-, Hetaryl-)-[1,2,4]triazolo[1,5-c]quinazolines. Sci Pharm. 2013 Apr-Jun;81(2):359-91. doi: 10.3797/scipharm.1211-08. Epub 2012 Dec 23. PMID: 23833709; PMCID: PMC3700071.
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Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the .

Journal of personalized medicine

Ilyechova EY, Miliukhina IV, Karpenko MN, Orlov IA, Puchkova LV, Samsonov SA.
PMID: 31426520
J Pers Med. 2019 Aug 17;9(3). doi: 10.3390/jpm9030041.

In this paper, we report a clinically proven case of Parkinson's disease (PD) with early onset in a patient who is a heterozygous mutation carrier of

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Ilyechova EY, Miliukhina IV, Karpenko MN, et al. Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the . J Pers Med. 2019;9(3)doi: 10.3390/jpm9030041.
Ilyechova, E. Y., Miliukhina, I. V., Karpenko, M. N., Orlov, I. A., Puchkova, L. V., & Samsonov, S. A. (2019). Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the . Journal of personalized medicine, 9(3), . https://doi.org/10.3390/jpm9030041
Ilyechova, Ekaterina Y, et al. "Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the ." Journal of personalized medicine vol. 9,3 (2019). doi: https://doi.org/10.3390/jpm9030041
Ilyechova EY, Miliukhina IV, Karpenko MN, Orlov IA, Puchkova LV, Samsonov SA. Case of Early-Onset Parkinson's Disease in a Heterozygous Mutation Carrier of the . J Pers Med. 2019 Aug 17;9(3). doi: 10.3390/jpm9030041. PMID: 31426520; PMCID: PMC6789574.
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Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment.

Materials (Basel, Switzerland)

Kuznetsov KA, Stepanova AO, Kvon RI, Douglas TEL, Kuznetsov NA, Chernonosova VS, Zaporozhchenko IA, Kharkova MV, Romanova IV, Karpenko AA, Laktionov PP.
PMID: 30400260
Materials (Basel). 2018 Nov 02;11(11). doi: 10.3390/ma11112176.

Paclitaxel is a natural, highly lipophilic anti proliferative drug widely used in medicine. We have studied the release of tritium-labeled paclitaxel (³H-PTX) from matrices destined for the coating of vascular stents and produced by the electrospinning method from the...

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Kuznetsov KA, Stepanova AO, Kvon RI, et al. Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment. Materials (Basel). 2018;11(11)doi: 10.3390/ma11112176.
Kuznetsov, K. A., Stepanova, A. O., Kvon, R. I., Douglas, T. E. L., Kuznetsov, N. A., Chernonosova, V. S., Zaporozhchenko, I. A., Kharkova, M. V., Romanova, I. V., Karpenko, A. A., & Laktionov, P. P. (2018). Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment. Materials (Basel, Switzerland), 11(11), . https://doi.org/10.3390/ma11112176
Kuznetsov, Konstantin A, et al. "Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment." Materials (Basel, Switzerland) vol. 11,11 (2018). doi: https://doi.org/10.3390/ma11112176
Kuznetsov KA, Stepanova AO, Kvon RI, Douglas TEL, Kuznetsov NA, Chernonosova VS, Zaporozhchenko IA, Kharkova MV, Romanova IV, Karpenko AA, Laktionov PP. Electrospun Produced 3D Matrices for Covering of Vascular Stents: Paclitaxel Release Depending on Fiber Structure and Composition of the External Environment. Materials (Basel). 2018 Nov 02;11(11). doi: 10.3390/ma11112176. PMID: 30400260; PMCID: PMC6265738.
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Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats.

Biological trace element research

Nikitchenko YV, Klochkov VK, Kavok NS, Karpenko NA, Nikitchenko IV, Yefimova SL, Bozhkov AI.
PMID: 33900529
Biol Trace Elem Res. 2022 Mar;200(3):1237-1247. doi: 10.1007/s12011-021-02734-x. Epub 2021 Apr 26.

Effect of prolong use of orthovanadate nanoparticles (GdVO

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Nikitchenko YV, Klochkov VK, Kavok NS, et al. Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats. Biol Trace Elem Res. 2021;200(3):1237-1247doi: 10.1007/s12011-021-02734-x.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Nikitchenko, I. V., Yefimova, S. L., & Bozhkov, A. I. (2022). Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats. Biological trace element research, 200(3), 1237-1247. https://doi.org/10.1007/s12011-021-02734-x
Nikitchenko, Yuri V, et al. "Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats." Biological trace element research vol. 200,3 (2022): 1237-1247. doi: https://doi.org/10.1007/s12011-021-02734-x
Nikitchenko YV, Klochkov VK, Kavok NS, Karpenko NA, Nikitchenko IV, Yefimova SL, Bozhkov AI. Comparative Studies of Orthovanadate Nanoparticles and Metformin on Life Quality and Survival of Senile Wistar Rats. Biol Trace Elem Res. 2022 Mar;200(3):1237-1247. doi: 10.1007/s12011-021-02734-x. Epub 2021 Apr 26. PMID: 33900529.
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Asynchronous faculty evaluation using videos for remote learning exercises.

Journal of dental education

Siddanna GD, Karpenko AE, Sterlitz SJ, Fasbinder DJ.
PMID: 33314142
J Dent Educ. 2020 Dec 13; doi: 10.1002/jdd.12522. Epub 2020 Dec 13.

No abstract available.

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Siddanna GD, Karpenko AE, Sterlitz SJ, et al. Asynchronous faculty evaluation using videos for remote learning exercises. J Dent Educ. 2020;doi: 10.1002/jdd.12522.
Siddanna, G. D., Karpenko, A. E., Sterlitz, S. J., & Fasbinder, D. J. (2020). Asynchronous faculty evaluation using videos for remote learning exercises. Journal of dental education, . https://doi.org/10.1002/jdd.12522
Siddanna, Geetha Duddanahalli, et al. "Asynchronous faculty evaluation using videos for remote learning exercises." Journal of dental education vol. (2020). doi: https://doi.org/10.1002/jdd.12522
Siddanna GD, Karpenko AE, Sterlitz SJ, Fasbinder DJ. Asynchronous faculty evaluation using videos for remote learning exercises. J Dent Educ. 2020 Dec 13; doi: 10.1002/jdd.12522. Epub 2020 Dec 13. PMID: 33314142.
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Virtual online learning communities reducing dental student stress and anxiety.

Journal of dental education

Karpenko AE, Sterlitz SJ, Garcia-Hammaker SS.
PMID: 32935361
J Dent Educ. 2020 Sep 15; doi: 10.1002/jdd.12430. Epub 2020 Sep 15.

No abstract available.

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Karpenko AE, Sterlitz SJ, Garcia-Hammaker SS. Virtual online learning communities reducing dental student stress and anxiety. J Dent Educ. 2020;doi: 10.1002/jdd.12430.
Karpenko, A. E., Sterlitz, S. J., & Garcia-Hammaker, S. S. (2020). Virtual online learning communities reducing dental student stress and anxiety. Journal of dental education, . https://doi.org/10.1002/jdd.12430
Karpenko, Amy E, et al. "Virtual online learning communities reducing dental student stress and anxiety." Journal of dental education vol. (2020). doi: https://doi.org/10.1002/jdd.12430
Karpenko AE, Sterlitz SJ, Garcia-Hammaker SS. Virtual online learning communities reducing dental student stress and anxiety. J Dent Educ. 2020 Sep 15; doi: 10.1002/jdd.12430. Epub 2020 Sep 15. PMID: 32935361.
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Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope.

Vaccines

Rudometov AP, Chikaev AN, Rudometova NB, Antonets DV, Lomzov AA, Kaplina ON, Ilyichev AA, Karpenko LI.
PMID: 31390770
Vaccines (Basel). 2019 Aug 06;7(3). doi: 10.3390/vaccines7030083.

The construction of artificial proteins using conservative B-cell and T-cell epitopes is believed to be a promising approach for a vaccine design against diverse viral infections. This article describes the development of an artificial HIV-1 immunogen using a polyepitope...

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Rudometov AP, Chikaev AN, Rudometova NB, et al. Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope. Vaccines (Basel). 2019;7(3)doi: 10.3390/vaccines7030083.
Rudometov, A. P., Chikaev, A. N., Rudometova, N. B., Antonets, D. V., Lomzov, A. A., Kaplina, O. N., Ilyichev, A. A., & Karpenko, L. I. (2019). Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope. Vaccines, 7(3), . https://doi.org/10.3390/vaccines7030083
Rudometov, Andrey P, et al. "Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope." Vaccines vol. 7,3 (2019). doi: https://doi.org/10.3390/vaccines7030083
Rudometov AP, Chikaev AN, Rudometova NB, Antonets DV, Lomzov AA, Kaplina ON, Ilyichev AA, Karpenko LI. Artificial Anti-HIV-1 Immunogen Comprising Epitopes of Broadly Neutralizing Antibodies 2F5, 10E8, and a Peptide Mimic of VRC01 Discontinuous Epitope. Vaccines (Basel). 2019 Aug 06;7(3). doi: 10.3390/vaccines7030083. PMID: 31390770; PMCID: PMC6789618.
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Corrigendum to "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson's disease" [Cell. Immunol. 327 (2018) 77-82].

Cellular immunology

Karpenko MN, Vasilishina AA, Gromova EA, Muruzheva ZM, Bernadotte A.
PMID: 30213645
Cell Immunol. 2018 Dec;334:99. doi: 10.1016/j.cellimm.2018.08.007. Epub 2018 Sep 10.

No abstract available.

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Karpenko MN, Vasilishina AA, Gromova EA, et al. Corrigendum to "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson's disease" [Cell. Immunol. 327 (2018) 77-82]. Cell Immunol. 2018;334:99doi: 10.1016/j.cellimm.2018.08.007.
Karpenko, M. N., Vasilishina, A. A., Gromova, E. A., Muruzheva, Z. M., & Bernadotte, A. (2018). Corrigendum to "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson's disease" [Cell. Immunol. 327 (2018) 77-82]. Cellular immunology, 33499. https://doi.org/10.1016/j.cellimm.2018.08.007
Karpenko, M N, et al. "Corrigendum to "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson's disease" [Cell. Immunol. 327 (2018) 77-82]." Cellular immunology vol. 334 (2018): 99. doi: https://doi.org/10.1016/j.cellimm.2018.08.007
Karpenko MN, Vasilishina AA, Gromova EA, Muruzheva ZM, Bernadotte A. Corrigendum to "Interleukin-1β, interleukin-1 receptor antagonist, interleukin-6, interleukin-10, and tumor necrosis factor-α levels in CSF and serum in relation to the clinical diversity of Parkinson's disease" [Cell. Immunol. 327 (2018) 77-82]. Cell Immunol. 2018 Dec;334:99. doi: 10.1016/j.cellimm.2018.08.007. Epub 2018 Sep 10. PMID: 30213645.
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Emission characteristics of H- ion source with inverse gas magnetron geometry.

The Review of scientific instruments

Baturin VA, Litvinov PA, Pustovoitov SA, Karpenko AY.
PMID: 20192380
Rev Sci Instrum. 2010 Feb;81(2):02A710. doi: 10.1063/1.3271171.

The work is dedicated to the experimental investigation of the intense volume-plasma H(-) ion source. Preliminary experimental researches of two parameters of the upgraded source--emission density of H(-) ions and gas flow--are represented below. In plasma volume of noncesium...

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Baturin VA, Litvinov PA, Pustovoitov SA, et al. Emission characteristics of H- ion source with inverse gas magnetron geometry. Rev Sci Instrum. 2010;81(2):02A710doi: 10.1063/1.3271171.
Baturin, V. A., Litvinov, P. A., Pustovoitov, S. A., & Karpenko, A. Y. (2010). Emission characteristics of H- ion source with inverse gas magnetron geometry. The Review of scientific instruments, 81(2), 02A710. https://doi.org/10.1063/1.3271171
Baturin, V A, et al. "Emission characteristics of H- ion source with inverse gas magnetron geometry." The Review of scientific instruments vol. 81,2 (2010): 02A710. doi: https://doi.org/10.1063/1.3271171
Baturin VA, Litvinov PA, Pustovoitov SA, Karpenko AY. Emission characteristics of H- ion source with inverse gas magnetron geometry. Rev Sci Instrum. 2010 Feb;81(2):02A710. doi: 10.1063/1.3271171. PMID: 20192380.
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Erratum to: Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells.

Bulletin of experimental biology and medicine

Nazarkina ZhK, Kharkova MV, Antonets DV, Morozkin ES, Bazhan SI, Karpenko LI, Vlassov VV, Ilyichev AA, Laktionov PP.
PMID: 27037926
Bull Exp Biol Med. 2016 Mar;160(5):727. doi: 10.1007/s10517-016-3261-1.

No abstract available.

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Nazarkina ZhK, Kharkova MV, Antonets DV, et al. Erratum to: Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells. Bull Exp Biol Med. 2016;160(5):727doi: 10.1007/s10517-016-3261-1.
Nazarkina, Z. h. K., Kharkova, M. V., Antonets, D. V., Morozkin, E. S., Bazhan, S. I., Karpenko, L. I., Vlassov, V. V., Ilyichev, A. A., & Laktionov, P. P. (2016). Erratum to: Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells. Bulletin of experimental biology and medicine, 160(5), 727. https://doi.org/10.1007/s10517-016-3261-1
Nazarkina, Zh K, et al. "Erratum to: Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells." Bulletin of experimental biology and medicine vol. 160,5 (2016): 727. doi: https://doi.org/10.1007/s10517-016-3261-1
Nazarkina ZhK, Kharkova MV, Antonets DV, Morozkin ES, Bazhan SI, Karpenko LI, Vlassov VV, Ilyichev AA, Laktionov PP. Erratum to: Design of Polyepitope DNA Vaccine against Breast Carcinoma Cells and Analysis of Its Expression in Dendritic Cells. Bull Exp Biol Med. 2016 Mar;160(5):727. doi: 10.1007/s10517-016-3261-1. PMID: 27037926.
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Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus.

Viruses

Shchelkunov SN, Sergeev AA, Yakubitskiy SN, Titova KA, Pyankov SA, Kolosova IV, Starostina EV, Borgoyakova MB, Zadorozhny AM, Kisakov DN, Shulgina IS, Karpenko LI.
PMID: 34452494
Viruses. 2021 Aug 17;13(8). doi: 10.3390/v13081631.

Mass vaccination has played a critical role in the global eradication of smallpox. Various vaccinia virus (VACV) strains, whose origin has not been clearly documented in most cases, have been used as live vaccines in different countries. These VACV...

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Shchelkunov SN, Sergeev AA, Yakubitskiy SN, et al. Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses. 2021;13(8)doi: 10.3390/v13081631.
Shchelkunov, S. N., Sergeev, A. A., Yakubitskiy, S. N., Titova, K. A., Pyankov, S. A., Kolosova, I. V., Starostina, E. V., Borgoyakova, M. B., Zadorozhny, A. M., Kisakov, D. N., Shulgina, I. S., & Karpenko, L. I. (2021). Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses, 13(8), . https://doi.org/10.3390/v13081631
Shchelkunov, Sergei N, et al. "Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus." Viruses vol. 13,8 (2021). doi: https://doi.org/10.3390/v13081631
Shchelkunov SN, Sergeev AA, Yakubitskiy SN, Titova KA, Pyankov SA, Kolosova IV, Starostina EV, Borgoyakova MB, Zadorozhny AM, Kisakov DN, Shulgina IS, Karpenko LI. Adaptive Immune Response to Vaccinia Virus LIVP Infection of BALB/c Mice and Protection against Lethal Reinfection with Cowpox Virus. Viruses. 2021 Aug 17;13(8). doi: 10.3390/v13081631. PMID: 34452494; PMCID: PMC8402668.
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Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria.

Biological trace element research

Nikitchenko YV, Klochkov VK, Kavok NS, Karpenko NA, Yefimova SL, Nikitchenko IV, Bozhkov AI.
PMID: 32504398
Biol Trace Elem Res. 2021 Mar;199(3):1213. doi: 10.1007/s12011-020-02225-5.

No abstract available.

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Nikitchenko YV, Klochkov VK, Kavok NS, et al. Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria. Biol Trace Elem Res. 2021;199(3):1213doi: 10.1007/s12011-020-02225-5.
Nikitchenko, Y. V., Klochkov, V. K., Kavok, N. S., Karpenko, N. A., Yefimova, S. L., Nikitchenko, I. V., & Bozhkov, A. I. (2021). Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria. Biological trace element research, 199(3), 1213. https://doi.org/10.1007/s12011-020-02225-5
Nikitchenko, Yuri V, et al. "Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria." Biological trace element research vol. 199,3 (2021): 1213. doi: https://doi.org/10.1007/s12011-020-02225-5
Nikitchenko YV, Klochkov VK, Kavok NS, Karpenko NA, Yefimova SL, Nikitchenko IV, Bozhkov AI. Correction to: Age-Related Effects of Orthovanadate Nanoparticles Involve Activation of GSH-Dependent Antioxidant System in Liver Mitochondria. Biol Trace Elem Res. 2021 Mar;199(3):1213. doi: 10.1007/s12011-020-02225-5. PMID: 32504398.
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