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A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief).

Journal of pain research

Inoue S, Saito Y, Tsuneto S, Aruga E, Ide A, Kakurai Y.
PMID: 28860850
J Pain Res. 2017 Aug 18;10:1953-1962. doi: 10.2147/JPR.S136937. eCollection 2017.

BACKGROUND: In Japan, there are limited options for switching opioid analgesics. Hydromorphone is an opioid analgesic that is routinely used instead of morphine for cancer pain; however, it is not yet available in Japan. The aim of this study...

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Inoue S, Saito Y, Tsuneto S, et al. A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief). J Pain Res. 2017;10:1953-1962doi: 10.2147/JPR.S136937.
Inoue, S., Saito, Y., Tsuneto, S., Aruga, E., Ide, A., & Kakurai, Y. (2017). A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief). Journal of pain research, 101953-1962. https://doi.org/10.2147/JPR.S136937
Inoue, Satoshi, et al. "A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief)." Journal of pain research vol. 10 (2017): 1953-1962. doi: https://doi.org/10.2147/JPR.S136937
Inoue S, Saito Y, Tsuneto S, Aruga E, Ide A, Kakurai Y. A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief). J Pain Res. 2017 Aug 18;10:1953-1962. doi: 10.2147/JPR.S136937. eCollection 2017. PMID: 28860850; PMCID: PMC5571837.
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Anisotropy of the electro-optic Kerr effect in polymer-stabilized blue phases.

Physical review. E, Statistical, nonlinear, and soft matter physics

Kawata Y, Yoshida H, Tanaka S, Konkanok A, Ozaki M, Kikuchi H.
PMID: 25768521
Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Feb;91(2):022503. doi: 10.1103/PhysRevE.91.022503. Epub 2015 Feb 27.

Liquid crystalline polymer stabilized blue phases (PSBPs) are candidate materials for next generation electro-optic switching devices because they form a self-organized three-dimensional periodic structure and exhibit a fast response time of submillisecond order. Considering the crystallographic structures of PSBPs,...

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Kawata Y, Yoshida H, Tanaka S, et al. Anisotropy of the electro-optic Kerr effect in polymer-stabilized blue phases. Phys Rev E Stat Nonlin Soft Matter Phys. 2015;91(2):022503doi: 10.1103/PhysRevE.91.022503.
Kawata, Y., Yoshida, H., Tanaka, S., Konkanok, A., Ozaki, M., & Kikuchi, H. (2015). Anisotropy of the electro-optic Kerr effect in polymer-stabilized blue phases. Physical review. E, Statistical, nonlinear, and soft matter physics, 91(2), 022503. https://doi.org/10.1103/PhysRevE.91.022503
Kawata, Yuto, et al. "Anisotropy of the electro-optic Kerr effect in polymer-stabilized blue phases." Physical review. E, Statistical, nonlinear, and soft matter physics vol. 91,2 (2015): 022503. doi: https://doi.org/10.1103/PhysRevE.91.022503
Kawata Y, Yoshida H, Tanaka S, Konkanok A, Ozaki M, Kikuchi H. Anisotropy of the electro-optic Kerr effect in polymer-stabilized blue phases. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Feb;91(2):022503. doi: 10.1103/PhysRevE.91.022503. Epub 2015 Feb 27. PMID: 25768521.
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Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis.

Hepatology research : the official journal of the Japan Society of Hepatology

Naeshiro N, Aikata H, Hyogo H, Kan H, Fujino H, Kobayashi T, Fukuhara T, Honda Y, Nakahara T, Ohno A, Miyaki D, Murakami E, Kawaoka T, Tsuge M, Hiraga N, Hiramatsu A, Imamura M, Kawakami Y, Ochi H, Chayama K.
PMID: 25088236
Hepatol Res. 2015 Jun;45(6):656-62. doi: 10.1111/hepr.12400. Epub 2014 Sep 02.

AIM: To assess the efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis.METHODS: A consecutive 26 cirrhotic patients with PVT were enrolled in this retrospective cohort...

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Naeshiro N, Aikata H, Hyogo H, et al. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis. Hepatol Res. 2014;45(6):656-62doi: 10.1111/hepr.12400.
Naeshiro, N., Aikata, H., Hyogo, H., Kan, H., Fujino, H., Kobayashi, T., Fukuhara, T., Honda, Y., Nakahara, T., Ohno, A., Miyaki, D., Murakami, E., Kawaoka, T., Tsuge, M., Hiraga, N., Hiramatsu, A., Imamura, M., Kawakami, Y., Ochi, H., & Chayama, K. (2015). Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis. Hepatology research : the official journal of the Japan Society of Hepatology, 45(6), 656-62. https://doi.org/10.1111/hepr.12400
Naeshiro, Noriaki, et al. "Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis." Hepatology research : the official journal of the Japan Society of Hepatology vol. 45,6 (2015): 656-62. doi: https://doi.org/10.1111/hepr.12400
Naeshiro N, Aikata H, Hyogo H, Kan H, Fujino H, Kobayashi T, Fukuhara T, Honda Y, Nakahara T, Ohno A, Miyaki D, Murakami E, Kawaoka T, Tsuge M, Hiraga N, Hiramatsu A, Imamura M, Kawakami Y, Ochi H, Chayama K. Efficacy and safety of the anticoagulant drug, danaparoid sodium, in the treatment of portal vein thrombosis in patients with liver cirrhosis. Hepatol Res. 2015 Jun;45(6):656-62. doi: 10.1111/hepr.12400. Epub 2014 Sep 02. PMID: 25088236.
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Clinicopathological Phenotype and Genetics of X-Linked Dystonia-Parkinsonism (XDP; DYT3; Lubag).

Brain sciences

Kawarai T, Morigaki R, Kaji R, Goto S.
PMID: 28672841
Brain Sci. 2017 Jun 26;7(7). doi: 10.3390/brainsci7070072.

X-linked dystonia-parkinsonism (XDP; OMIM314250), also referred to as DYT3 dystonia or "Lubag" disease, was first described as an endemic disease in the Philippine island of Panay. XDP is an adult-onset movement disorder characterized by progressive and severe dystonia followed...

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Kawarai T, Morigaki R, Kaji R, et al. Clinicopathological Phenotype and Genetics of X-Linked Dystonia-Parkinsonism (XDP; DYT3; Lubag). Brain Sci. 2017;7(7)doi: 10.3390/brainsci7070072.
Kawarai, T., Morigaki, R., Kaji, R., & Goto, S. (2017). Clinicopathological Phenotype and Genetics of X-Linked Dystonia-Parkinsonism (XDP; DYT3; Lubag). Brain sciences, 7(7), . https://doi.org/10.3390/brainsci7070072
Kawarai, Toshitaka, et al. "Clinicopathological Phenotype and Genetics of X-Linked Dystonia-Parkinsonism (XDP; DYT3; Lubag)." Brain sciences vol. 7,7 (2017). doi: https://doi.org/10.3390/brainsci7070072
Kawarai T, Morigaki R, Kaji R, Goto S. Clinicopathological Phenotype and Genetics of X-Linked Dystonia-Parkinsonism (XDP; DYT3; Lubag). Brain Sci. 2017 Jun 26;7(7). doi: 10.3390/brainsci7070072. PMID: 28672841; PMCID: PMC5532585.
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Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes: A case report.

World journal of gastrointestinal oncology

Kawara F, Tanaka S, Yamasaki T, Morita Y, Ohara Y, Okabe Y, Hoshi N, Toyonaga T, Umegaki E, Yokozaki H, Hirose T, Azuma T.
PMID: 28656077
World J Gastrointest Oncol. 2017 Jun 15;9(6):263-267. doi: 10.4251/wjgo.v9.i6.263.

A 66-year-old man was diagnosed with a gastric submucosal tumor. Endoscopic ultrasound (EUS) revealed an iso/hypoechoic mass in the third layer. No malignant cells were detected in a histological examination. Yearly follow-up endoscopy and EUS showed the slow growth...

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Kawara F, Tanaka S, Yamasaki T, et al. Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes: A case report. World J Gastrointest Oncol. 2017;9(6):263-267doi: 10.4251/wjgo.v9.i6.263.
Kawara, F., Tanaka, S., Yamasaki, T., Morita, Y., Ohara, Y., Okabe, Y., Hoshi, N., Toyonaga, T., Umegaki, E., Yokozaki, H., Hirose, T., & Azuma, T. (2017). Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes: A case report. World journal of gastrointestinal oncology, 9(6), 263-267. https://doi.org/10.4251/wjgo.v9.i6.263
Kawara, Fumiaki, et al. "Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes: A case report." World journal of gastrointestinal oncology vol. 9,6 (2017): 263-267. doi: https://doi.org/10.4251/wjgo.v9.i6.263
Kawara F, Tanaka S, Yamasaki T, Morita Y, Ohara Y, Okabe Y, Hoshi N, Toyonaga T, Umegaki E, Yokozaki H, Hirose T, Azuma T. Gastric plexiform fibromyxoma resected by endoscopic submucosal dissection after observation of chronological changes: A case report. World J Gastrointest Oncol. 2017 Jun 15;9(6):263-267. doi: 10.4251/wjgo.v9.i6.263. PMID: 28656077; PMCID: PMC5472557.
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CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue.

Oncology letters

Suzuki S, Honda K, Nanjo H, Iikawa N, Tsuji T, Kawasaki Y, Yamazaki K, Sato T, Saito H, Shiina K, Ishikawa K.
PMID: 29085466
Oncol Lett. 2017 Oct;14(4):4670-4676. doi: 10.3892/ol.2017.6808. Epub 2017 Aug 24.

Cervical lymph node metastasis causes a poor prognosis in cases of stage T1-T2 squamous cell carcinoma (SCC) of the tongue. Recent studies have reported that cluster of differentiation (CD)147, also known as extracellular matrix metalloproteinase inducer, contributes to tumor...

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Suzuki S, Honda K, Nanjo H, et al. CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue. Oncol Lett. 2017;14(4):4670-4676doi: 10.3892/ol.2017.6808.
Suzuki, S., Honda, K., Nanjo, H., Iikawa, N., Tsuji, T., Kawasaki, Y., Yamazaki, K., Sato, T., Saito, H., Shiina, K., & Ishikawa, K. (2017). CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue. Oncology letters, 14(4), 4670-4676. https://doi.org/10.3892/ol.2017.6808
Suzuki, Shinsuke, et al. "CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue." Oncology letters vol. 14,4 (2017): 4670-4676. doi: https://doi.org/10.3892/ol.2017.6808
Suzuki S, Honda K, Nanjo H, Iikawa N, Tsuji T, Kawasaki Y, Yamazaki K, Sato T, Saito H, Shiina K, Ishikawa K. CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue. Oncol Lett. 2017 Oct;14(4):4670-4676. doi: 10.3892/ol.2017.6808. Epub 2017 Aug 24. PMID: 29085466; PMCID: PMC5649530.
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Observation of X-ray and Auger electron spectra in a 4π proportional counter for 4π(e, X)-γ coincidence measurements.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Yunoki A, Kawada Y, Hino Y.
PMID: 24373820
Appl Radiat Isot. 2014 May;87:179-82. doi: 10.1016/j.apradiso.2013.11.105. Epub 2013 Dec 10.

For the standardization of electron capture nuclides followed by γ-transitions, the 4π(e, X)-γ coincidence counting method is mainly adopted. To examine how the spectra of the (e, X) channel change with gas nature and pressure, pulse-height spectrum measurements of...

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Yunoki A, Kawada Y, Hino Y. Observation of X-ray and Auger electron spectra in a 4π proportional counter for 4π(e, X)-γ coincidence measurements. Appl Radiat Isot. 2013;87:179-82doi: 10.1016/j.apradiso.2013.11.105.
Yunoki, A., Kawada, Y., & Hino, Y. (2014). Observation of X-ray and Auger electron spectra in a 4π proportional counter for 4π(e, X)-γ coincidence measurements. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 87179-82. https://doi.org/10.1016/j.apradiso.2013.11.105
Yunoki, Akira, et al. "Observation of X-ray and Auger electron spectra in a 4π proportional counter for 4π(e, X)-γ coincidence measurements." Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine vol. 87 (2014): 179-82. doi: https://doi.org/10.1016/j.apradiso.2013.11.105
Yunoki A, Kawada Y, Hino Y. Observation of X-ray and Auger electron spectra in a 4π proportional counter for 4π(e, X)-γ coincidence measurements. Appl Radiat Isot. 2014 May;87:179-82. doi: 10.1016/j.apradiso.2013.11.105. Epub 2013 Dec 10. PMID: 24373820.
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Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer.

Nano letters

Naganuma H, Kim G, Kawada Y, Inami N, Hatakeyama K, Iihama S, Nazrul Islam KM, Oogane M, Mizukami S, Ando Y.
PMID: 25549140
Nano Lett. 2015 Jan 14;15(1):623-8. doi: 10.1021/nl504114v. Epub 2015 Jan 02.

Spin dynamics excited by spin-polarized current in magnetic tunnel junctions (MTJs) is potentially useful in nanoscale electrical oscillation sources and detection devices. A spin oscillator/detector should work at a high frequency, such as that of a millimeter-wave, where the...

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Naganuma H, Kim G, Kawada Y, et al. Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer. Nano Lett. 2015;15(1):623-8doi: 10.1021/nl504114v.
Naganuma, H., Kim, G., Kawada, Y., Inami, N., Hatakeyama, K., Iihama, S., Nazrul Islam, K. M., Oogane, M., Mizukami, S., & Ando, Y. (2015). Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer. Nano letters, 15(1), 623-8. https://doi.org/10.1021/nl504114v
Naganuma, Hiroshi, et al. "Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer." Nano letters vol. 15,1 (2015): 623-8. doi: https://doi.org/10.1021/nl504114v
Naganuma H, Kim G, Kawada Y, Inami N, Hatakeyama K, Iihama S, Nazrul Islam KM, Oogane M, Mizukami S, Ando Y. Electrical detection of millimeter-waves by magnetic tunnel junctions using perpendicular magnetized L10-FePd free layer. Nano Lett. 2015 Jan 14;15(1):623-8. doi: 10.1021/nl504114v. Epub 2015 Jan 02. PMID: 25549140.
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Retinal arteriolar narrowing is associated with a 4-year risk of incident metabolic syndrome.

Nutrition & diabetes

Saito K, Kawasaki Y, Nagao Y, Kawasaki R.
PMID: 26098444
Nutr Diabetes. 2015 Jun 22;5:e165. doi: 10.1038/nutd.2015.15.

We aimed to determine whether retinal microvascular changes in vessel calibers at baseline are associated with the future risk of developing the metabolic syndrome over 4 years in an adult cohort of Japanese individuals (n=90) who attended a health-screening...

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Saito K, Kawasaki Y, Nagao Y, et al. Retinal arteriolar narrowing is associated with a 4-year risk of incident metabolic syndrome. Nutr Diabetes. 2015;5:e165doi: 10.1038/nutd.2015.15.
Saito, K., Kawasaki, Y., Nagao, Y., & Kawasaki, R. (2015). Retinal arteriolar narrowing is associated with a 4-year risk of incident metabolic syndrome. Nutrition & diabetes, 5e165. https://doi.org/10.1038/nutd.2015.15
Saito, K, et al. "Retinal arteriolar narrowing is associated with a 4-year risk of incident metabolic syndrome." Nutrition & diabetes vol. 5 (2015): e165. doi: https://doi.org/10.1038/nutd.2015.15
Saito K, Kawasaki Y, Nagao Y, Kawasaki R. Retinal arteriolar narrowing is associated with a 4-year risk of incident metabolic syndrome. Nutr Diabetes. 2015 Jun 22;5:e165. doi: 10.1038/nutd.2015.15. PMID: 26098444; PMCID: PMC4491856.
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Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions.

AMB Express

Kawata Y, Nishimura T, Matsushita I, Tsubota J.
PMID: 26989057
AMB Express. 2016 Mar;6(1):22. doi: 10.1186/s13568-016-0195-y. Epub 2016 Mar 18.

The alkaliphilic, halophilic bacterium Halomonas sp. KM-1 can utilize both hexose and pentose sugars for the intracellular storage of bioplastic poly-(R)-3-hydroxybutyric acid (PHB) under aerobic conditions. In this study, we investigated the effects of the sodium nitrate concentration on...

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Kawata Y, Nishimura T, Matsushita I, et al. Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions. AMB Express. 2016;6(1):22doi: 10.1186/s13568-016-0195-y.
Kawata, Y., Nishimura, T., Matsushita, I., & Tsubota, J. (2016). Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions. AMB Express, 6(1), 22. https://doi.org/10.1186/s13568-016-0195-y
Kawata, Yoshikazu, et al. "Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions." AMB Express vol. 6,1 (2016): 22. doi: https://doi.org/10.1186/s13568-016-0195-y
Kawata Y, Nishimura T, Matsushita I, Tsubota J. Efficient production and secretion of pyruvate from Halomonas sp. KM-1 under aerobic conditions. AMB Express. 2016 Mar;6(1):22. doi: 10.1186/s13568-016-0195-y. Epub 2016 Mar 18. PMID: 26989057; PMCID: PMC4798600.
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Aortic rupture due to radiation injury successfully treated with thoracic endovascular aortic repair.

Journal of surgical case reports

Kawatani Y, Kurobe H, Nakamura Y, Suda Y, Hori T.
PMID: 28560028
J Surg Case Rep. 2017 May 23;2017(5):rjx092. doi: 10.1093/jscr/rjx092. eCollection 2017 May.

Thoracic endovascular aortic repair (TEVAR) has been reported to be an effective treatment option for aortic emergencies. However, there are few reports about TEVAR for aortic rupture due to radiation injury. A 54-year-old man presented with haemoptysis. He had...

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Kawatani Y, Kurobe H, Nakamura Y, et al. Aortic rupture due to radiation injury successfully treated with thoracic endovascular aortic repair. J Surg Case Rep. 2017;2017(5):rjx092doi: 10.1093/jscr/rjx092.
Kawatani, Y., Kurobe, H., Nakamura, Y., Suda, Y., & Hori, T. (2017). Aortic rupture due to radiation injury successfully treated with thoracic endovascular aortic repair. Journal of surgical case reports, 2017(5), rjx092. https://doi.org/10.1093/jscr/rjx092
Kawatani, Yohei, et al. "Aortic rupture due to radiation injury successfully treated with thoracic endovascular aortic repair." Journal of surgical case reports vol. 2017,5 (2017): rjx092. doi: https://doi.org/10.1093/jscr/rjx092
Kawatani Y, Kurobe H, Nakamura Y, Suda Y, Hori T. Aortic rupture due to radiation injury successfully treated with thoracic endovascular aortic repair. J Surg Case Rep. 2017 May 23;2017(5):rjx092. doi: 10.1093/jscr/rjx092. eCollection 2017 May. PMID: 28560028; PMCID: PMC5441253.
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The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918.

Bioscience of microbiota, food and health

Kawada Y, Yokoyama S, Yanase E, Niwa T, Suzuki T.
PMID: 27508112
Biosci Microbiota Food Health. 2016;35(3):113-21. doi: 10.12938/bmfh.2015-023. Epub 2016 Mar 31.

Daidzein (DZN) is converted to equol (EQL) by intestinal bacteria. We previously reported that Eggerthella sp. YY7918, which is found in human feces, is an EQL-producing bacterium and analyzed its whole genomic sequence. We found three coding sequences (CDSs)...

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Kawada Y, Yokoyama S, Yanase E, et al. The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918. Biosci Microbiota Food Health. 2016;35(3):113-21doi: 10.12938/bmfh.2015-023.
Kawada, Y., Yokoyama, S., Yanase, E., Niwa, T., & Suzuki, T. (2016). The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918. Bioscience of microbiota, food and health, 35(3), 113-21. https://doi.org/10.12938/bmfh.2015-023
Kawada, Yuika, et al. "The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918." Bioscience of microbiota, food and health vol. 35,3 (2016): 113-21. doi: https://doi.org/10.12938/bmfh.2015-023
Kawada Y, Yokoyama S, Yanase E, Niwa T, Suzuki T. The production of S-equol from daidzein is associated with a cluster of three genes in Eggerthella sp. YY7918. Biosci Microbiota Food Health. 2016;35(3):113-21. doi: 10.12938/bmfh.2015-023. Epub 2016 Mar 31. PMID: 27508112; PMCID: PMC4965515.
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