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Showing 1 to 12 of 41 entries
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Amplification of HER-2/neu oncogene in human ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Leary JA, Edwards BG, Houghton CR, Kefford RF, Friedlander ML.
PMID: 11576271
Int J Gynecol Cancer. 1992 Nov;2(6):291-4. doi: 10.1046/j.1525-1438.1992.02060291.x.

Amplification and/or increased expression of the HER-2/neu oncogene has been reported to occur in ovarian tumors and possibly to correlate with biologic behavior and prognosis. The frequency with which amplification is reported to occur is quite variable ranging from...

Auxin-Gibberellin Interaction in Rice Coleoptile Elongation.

Plant physiology

Kefford NP.
PMID: 16655662
Plant Physiol. 1962 May;37(3):380-6. doi: 10.1104/pp.37.3.380.

No abstract available.

Steady state growth of avena coleoptile sections in high auxin concentrations.

Plant physiology

Kefford NP, Bonner J.
PMID: 16655513
Plant Physiol. 1961 May;36(3):323-5. doi: 10.1104/pp.36.3.323.

No abstract available.

Symptomatic Histologically Proven Necrosis of Brain following Stereotactic Radiation and Ipilimumab in Six Lesions in Four Melanoma Patients.

Case reports in oncological medicine

Du Four S, Hong A, Chan M, Charakidis M, Duerinck J, Wilgenhof S, Wang W, Feng L, Michotte A, Okera M, Shivalingam B, Fogarty G, Kefford R, Neyns B.
PMID: 25105043
Case Rep Oncol Med. 2014;2014:417913. doi: 10.1155/2014/417913. Epub 2014 Jul 01.

Four cases previously treated with ipilimumab with a total of six histologically confirmed symptomatic lesions of RNB without any sign of active tumour following stereotactic irradiation of MBM are reported. These lesions were all originally thought to be disease...

First-in-human, phase I/IIa study of CRLX301, a nanoparticle drug conjugate containing docetaxel, in patients with advanced or metastatic solid malignancies.

Investigational new drugs

Piha-Paul SA, Thein KZ, De Souza P, Kefford R, Gangadhar T, Smith C, Schuster S, Zamboni WC, Dees CE, Markman B.
PMID: 33594602
Invest New Drugs. 2021 Aug;39(4):1047-1056. doi: 10.1007/s10637-021-01081-x. Epub 2021 Feb 16.

Background This was a phase I/IIa study to investigate the tolerability, efficacy and pharmacokinetics (PK)/ pharmacodynamics (PD) of CRLX301, CDP-based nanoparticle formulation of docetaxel. Methods The study was conducted in two parts. In part 1, dose-escalation using a standard...

The Effects of Road De-icing Salts on Water Quality and Macroinvertebrates in Australian Alpine Areas.

Archives of environmental contamination and toxicology

Shenton MD, Nichols SJ, Bray JP, Moulding BJG, Kefford BJ.
PMID: 33877368
Arch Environ Contam Toxicol. 2021 Apr 20; doi: 10.1007/s00244-021-00827-1. Epub 2021 Apr 20.

The application of road de-icing salts has the potential to salinize fresh waters and degrade habitat for aquatic organisms. In the Australian Alps, the ecological effects of even small salinity increases from de-icing may be different than in North...

Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma.

Cancers

Diefenbach RJ, Lee JH, Strbenac D, Yang JYH, Menzies AM, Carlino MS, Long GV, Spillane AJ, Stretch JR, Saw RPM, Thompson JF, Ch'ng S, Scolyer RA, Kefford RF, Rizos H.
PMID: 31795494
Cancers (Basel). 2019 Nov 29;11(12). doi: 10.3390/cancers11121905.

The use of circulating tumor DNA (ctDNA) to monitor cancer progression and response to therapy has significant potential but there is only limited data on whether this technique can detect the presence of low frequency subclones that may ultimately...

Climate change as a contributor to human conflict.

Nature

Butler CD, Kefford BJ.
PMID: 29595780
Nature. 2018 Mar 29;555(7698):587. doi: 10.1038/d41586-018-03795-0.

No abstract available.

A novel model for metastasis suppression involving regulation of nuclear precursor messenger-RNA stability.

International journal of oncology

Henderson B, McDonald D, Jones S, Kefford R.
PMID: 21556563
Int J Oncol. 1995 Feb;6(2):483-6. doi: 10.3892/ijo.6.2.483.

Our previous data correlated urokinase plasminogen activator (uPA) gene activation with metastasis in different rat mammary carcinomas, However, inconsistent with this was the suppression of the uPA gene in the metastatic rat mammary carcinoma cell line, BC1. We have...

Gibberellin and growth in isolated wheat embryos.

Science (New York, N.Y.)

Kefford NP, Rijven AH.
PMID: 17842097
Science. 1966 Jan 07;151(3706):104-5. doi: 10.1126/science.151.3706.104.

Gibberellic acid promoted elongation growth in the coleoptiles and leaves of embryos from gamma-irradiated wheat grains whether the embryos were isolated or attached to the endosperm. Thus gibberellic acid affected this growth directly rather than indirectly through an effect...

The role of bacterial surface and substratum hydrophobicity in adhesion ofLeptospira biflexa serovarpatoc 1 to inert surfaces.

Microbial ecology

Kefford B, Marshall KC.
PMID: 24212922
Microb Ecol. 1986 Dec;12(4):315-22. doi: 10.1007/BF02098572.

Adhesion of the hydrophilicLeptospira biflexa serovarpatoc 1 (L. patoc) was consistently greater on inert hydrophobic surfaces than on hydrophilic surfaces (glass and plastic). When inert substrata were coated with fetal calf serum (FCS) or bovine serum albumin fraction V...

Corrigendum to "Sensitivity and specificity of macroinvertebrate responses to gradients of multiple agricultural stressors" [Environ. Pollut. 291 (December 2021) 118092].

Environmental pollution (Barking, Essex : 1987)

Brooks AJ, Bray J, Nichols SJ, Shenton M, Kaserzon S, Nally RM, Kefford BJ.
PMID: 34757125
Environ Pollut. 2022 Jan 15;293:118409. doi: 10.1016/j.envpol.2021.118409. Epub 2021 Oct 29.

No abstract available.

Showing 1 to 12 of 41 entries