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Showing 1 to 12 of 283 entries
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Catalytic, stereospecific syn-dichlorination of alkenes.

Nature chemistry

Cresswell AJ, Eey ST, Denmark SE.
PMID: 25615668
Nat Chem. 2014 Feb;7(2):146-52. doi: 10.1038/nchem.2141. Epub 2015 Jan 12.

As some of the oldest organic chemical reactions known, the ionic additions of elemental halogens such as bromine and chlorine to alkenes are prototypical examples of stereospecific reactions, typically delivering vicinal dihalides resulting from anti-addition. Although the invention of...

Hydrogen Bonding: HOC=O· · ·H-N vs. HOC=O· · ·H-C.

Monatshefte fur chemie

Dey SK, Datta S, Lightner DA.
PMID: 25745269
Monatsh Chem. 2014 Oct 01;145(10):1595-1609. doi: 10.1007/s00706-014-1257-y.

A chloroform-soluble dipyrrinone, 8,9-bis-(5-carboxypentyl)-2,3-bis-(2-methoxyethoxy)-10

Decidual Cox2 inhibition improves fetal and maternal outcomes in a preeclampsia-like mouse model.

JCI insight

Sones JL, Cha J, Woods AK, Bartos A, Heyward CY, Lob HE, Isroff CE, Butler SD, Shapiro SE, Dey SK, Davisson RL.
PMID: 27159542
JCI Insight. 2016 Mar 17;1(3). doi: 10.1172/jci.insight.75351.

Preeclampsia (PE) is a disorder of pregnancy that manifests as late gestational maternal hypertension and proteinuria and can be life-threatening to both the mother and baby. It is believed that abnormal placentation is responsible for the cascade of events...

A central support system can facilitate implementation and sustainability of a Classroom-based Undergraduate Research Experience (CURE) in Genomics.

CBE life sciences education

Lopatto D, Hauser C, Jones CJ, Paetkau D, Chandrasekaran V, Dunbar D, MacKinnon C, Stamm J, Alvarez C, Barnard D, Bedard JE, Bednarski AE, Bhalla S, Braverman JM, Burg M, Chung HM, DeJong RJ, DiAngelo JR, Du C, Eckdahl TT, Emerson J, Frary A, Frohlich D, Goodman AL, Gosser Y, Govind S, Haberman A, Hark AT, Hoogewerf A, Johnson D, Kadlec L, Kaehler M, Key SC, Kokan NP, Kopp OR, Kuleck GA, Lopilato J, Martinez-Cruzado JC, McNeil G, Mel S, Nagengast A, Overvoorde PJ, Parrish S, Preuss ML, Reed LD, Regisford EG, Revie D, Robic S, Roecklien-Canfield JA, Rosenwald AG, Rubin MR, Saville K, Schroeder S, Sharif KA, Shaw M, Skuse G, Smith CD, Smith M, Smith ST, Spana EP, Spratt M, Sreenivasan A, Thompson JS, Wawersik M, Wolyniak MJ, Youngblom J, Zhou L, Buhler J, Mardis E, Leung W, Shaffer CD, Threlfall J, Elgin SC.
PMID: 25452493
CBE Life Sci Educ. 2014;13(4):711-23. doi: 10.1187/cbe.13-10-0200.

In their 2012 report, the President's Council of Advisors on Science and Technology advocated "replacing standard science laboratory courses with discovery-based research courses"-a challenging proposition that presents practical and pedagogical difficulties. In this paper, we describe our collective experiences...

Quantitative evaluation and optimization of co-drugging to improve anti-HIV latency therapy.

Cellular and molecular bioengineering

Wong VC, Fong LE, Adams NM, Xue Q, Dey SS, Miller-Jensen K.
PMID: 26191086
Cell Mol Bioeng. 2014 Sep 01;7(3):320-333. doi: 10.1007/s12195-014-0336-9.

Human immunodeficiency virus 1 (HIV) latency remains a significant obstacle to curing infected patients. One promising therapeutic strategy is to purge the latent cellular reservoir by activating latent HIV with latency-reversing agents (LRAs). In some cases, co-drugging with multiple...

Total synthesis of (-)-platensimycin by advancing oxocarbenium- and iminium-mediated catalytic methods.

Chemistry (Weinheim an der Bergstrasse, Germany)

Eey ST, Lear MJ.
PMID: 25047997
Chemistry. 2014 Sep 01;20(36):11556-73. doi: 10.1002/chem.201400131. Epub 2014 Jul 22.

(-)-Platensimycin is a potent inhibitor of fatty acid synthase that holds promise in the treatment of metabolic disorders (e.g., diabetes and "fatty liver") and pathogenic infections (e.g., those caused by drug-resistant bacteria). Herein, we describe its total synthesis through...

A quasi-tetrahedral Cu4 cluster and a helical-chain copper (II) complex with single syn-anti carboxylate bridges: crystal structure and magnetic properties.

Inorganic chemistry

Dey SK, Bag B, Abdul Malik KM, El Fallah MS, Ribas J, Mitra S.
PMID: 12817958
Inorg Chem. 2003 Jun 30;42(13):4029-35. doi: 10.1021/ic0206488.

A tridentate Schiff base carboxylate ligand, derived from the condensation of pyridine 2-carboxaldehyde with anthranilic acid, reacts with copper trifluoroacetate salt to give rise to the helical chain complex [Cu(C(13)H(9)N(2)O(2))(F(3)CCO(2))](n)() (1) and with copper nitrate to give rise to...

Crystal structure and magnetic interactions in nickel(II) dibridged complexes formed by two azide groups or by both phenolate oxygen-azide, -thiocyanate, -carboxylate, or -cyanate groups.

Inorganic chemistry

Dey SK, Mondal N, El Fallah MS, Vicente R, Escuer A, Solans X, Font-Bardía M, Matsushita T, Gramlich V, Mitra S.
PMID: 15046520
Inorg Chem. 2004 Apr 05;43(7):2427-34. doi: 10.1021/ic0352553.

Tridentate/tetradentate Schiff base ligands L(1) and L(2), derived from the condensation of o-vanillin or pyridine-2-aldehyde with N,N-dimethylethylenediammine, react with nickel acetate or perchlorate salt and azide, cyanate, or thiocyanate to give rise to a series of dinuclear complexes of...

Supramolecular 'flat' Mn9 grid complexes--towards functional molecular platforms.

Dalton transactions (Cambridge, England : 2003)

Milway VA, Abedin SM, Niel V, Kelly TL, Dawe LN, Dey SK, Thompson DW, Miller DO, Alam MS, Müller P, Thompson LK.
PMID: 16751892
Dalton Trans. 2006 Jun 21;(23):2835-51. doi: 10.1039/b515801j. Epub 2006 May 12.

Flat, quantum dot like arrays of closely spaced, electron rich metal centres are seen as attractive subunits for device capability at the molecular level. Mn(II)9 grids, formed by self-assembly processes using 'tritopic' pyridine-2,6-dihydrazone ligands, provide easy and pre-programmable routes...

Supramolecular self-assembled polynuclear complexes from tritopic, tetratopic, and pentatopic ligands: structural, magnetic and surface studies.

Inorganic chemistry

Dey SK, Abedin TS, Dawe LN, Tandon SS, Collins JL, Thompson LK, Postnikov AV, Alam MS, Müller P.
PMID: 17696336
Inorg Chem. 2007 Sep 17;46(19):7767-81. doi: 10.1021/ic070336a. Epub 2007 Aug 14.

Polymetallic, highly organized molecular architectures can be created by "bottom-up" self-assembly methods using ligands with appropriately programmed coordination information. Ligands based on 2,6-picolyldihydrazone (tritopic and pentatopic) and 3,6-pyridazinedihydrazone (tetratopic) cores, with tridentate coordination pockets, are highly specific and lead...

Dynamics of plasmid maintenance in a CSTR upon square-wave perturbations in the dilution rate.

Biotechnology and bioengineering

Weber AE, San KY.
PMID: 18588205
Biotechnol Bioeng. 1989 Oct 20;34(8):1104-13. doi: 10.1002/bit.260340812.

The effects of forced oscillations in the dilution rate on a population of Escherichia coli K12 harboring the plasmid pBR322 in a chemostat with a nonselective medium were studied. In the constant dilution rate control experiments, the percentage of...

The effect of growth rate delays in substrate-inhibited kinetics on the optimal profile of fed-batch reactors.

Biotechnology and bioengineering

San KY, Stephanopoulos G.
PMID: 18555336
Biotechnol Bioeng. 1986 Mar;28(3):356-61. doi: 10.1002/bit.260280308.

No abstract available.

Showing 1 to 12 of 283 entries