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Showing 1 to 12 of 44 entries
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Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Nature

Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC.
PMID: 27706144
Nature. 2016 Dec 01;540(7631):150. doi: 10.1038/nature19851. Epub 2016 Oct 05.

No abstract available.

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Sousa CM, Biancur DE, Wang X, et al. Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. 2016;540(7631):150doi: 10.1038/nature19851.
Sousa, C. M., Biancur, D. E., Wang, X., Halbrook, C. J., Sherman, M. H., Zhang, L., Kremer, D., Hwang, R. F., Witkiewicz, A. K., Ying, H., Asara, J. M., Evans, R. M., Cantley, L. C., Lyssiotis, C. A., & Kimmelman, A. C. (2016). Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature, 540(7631), 150. https://doi.org/10.1038/nature19851
Sousa, Cristovão M, et al. "Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion." Nature vol. 540,7631 (2016): 150. doi: https://doi.org/10.1038/nature19851
Sousa CM, Biancur DE, Wang X, Halbrook CJ, Sherman MH, Zhang L, Kremer D, Hwang RF, Witkiewicz AK, Ying H, Asara JM, Evans RM, Cantley LC, Lyssiotis CA, Kimmelman AC. Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion. Nature. 2016 Dec 01;540(7631):150. doi: 10.1038/nature19851. Epub 2016 Oct 05. PMID: 27706144.
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Patient-Funded Trials: Opportunity or Liability?.

Cell stem cell

Wenner DM, Kimmelman J, London AJ.
PMID: 26253199
Cell Stem Cell. 2015 Aug 06;17(2):135-7. doi: 10.1016/j.stem.2015.07.016.

Patient-funded trials (PFTs) are gaining traction as a means of accelerating clinical translation. However, such trials sidestep mechanisms that promote rigor, relevance, efficiency, and fairness. We recommend that funding bodies or research institutions establish mechanisms for merit review of...

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Wenner DM, Kimmelman J, London AJ. Patient-Funded Trials: Opportunity or Liability?. Cell Stem Cell. 2015;17(2):135-7doi: 10.1016/j.stem.2015.07.016.
Wenner, D. M., Kimmelman, J., & London, A. J. (2015). Patient-Funded Trials: Opportunity or Liability?. Cell stem cell, 17(2), 135-7. https://doi.org/10.1016/j.stem.2015.07.016
Wenner, Danielle Marie, et al. "Patient-Funded Trials: Opportunity or Liability?." Cell stem cell vol. 17,2 (2015): 135-7. doi: https://doi.org/10.1016/j.stem.2015.07.016
Wenner DM, Kimmelman J, London AJ. Patient-Funded Trials: Opportunity or Liability?. Cell Stem Cell. 2015 Aug 06;17(2):135-7. doi: 10.1016/j.stem.2015.07.016. PMID: 26253199.
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Research in dental caries control.

The Journal of the Albert Einstein Medical Center, Philadelphia

KIMMELMAN BB, GROSSMAN B.
PMID: 13756004
J Albert Einstein Med Cent (Phila). 1961 Apr;9:102-5.

No abstract available.

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KIMMELMAN BB, GROSSMAN B. Research in dental caries control. J Albert Einstein Med Cent (Phila). 1961;9:102-5
KIMMELMAN, B. B., & GROSSMAN, B. (1961). Research in dental caries control. The Journal of the Albert Einstein Medical Center, Philadelphia, 9102-5.
KIMMELMAN, B B, and GROSSMAN, B. "Research in dental caries control." The Journal of the Albert Einstein Medical Center, Philadelphia vol. 9 (1961): 102-5.
KIMMELMAN BB, GROSSMAN B. Research in dental caries control. J Albert Einstein Med Cent (Phila). 1961 Apr;9:102-5. PMID: 13756004.
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Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone.

Cancer & metabolism

Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA.
PMID: 26462257
Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015.

BACKGROUND: Pancreatic ductal adenocarcinomas (PDA) activate a glutamine-dependent pathway of cytosolic nicotinamide adenine dinucleotide phosphate (NADPH) production to maintain redox homeostasis and support proliferation. Enzymes involved in this pathway (GLS1 (mitochondrial glutaminase 1), GOT1 (cytoplasmic glutamate oxaloacetate transaminase 1),...

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Chakrabarti G, Moore ZR, Luo X, et al. Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. Cancer Metab. 2015;3:12doi: 10.1186/s40170-015-0137-1.
Chakrabarti, G., Moore, Z. R., Luo, X., Ilcheva, M., Ali, A., Padanad, M., Zhou, Y., Xie, Y., Burma, S., Scaglioni, P. P., Cantley, L. C., DeBerardinis, R. J., Kimmelman, A. C., Lyssiotis, C. A., & Boothman, D. A. (2015). Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. Cancer & metabolism, 312. https://doi.org/10.1186/s40170-015-0137-1
Chakrabarti, Gaurab, et al. "Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone." Cancer & metabolism vol. 3 (2015): 12. doi: https://doi.org/10.1186/s40170-015-0137-1
Chakrabarti G, Moore ZR, Luo X, Ilcheva M, Ali A, Padanad M, Zhou Y, Xie Y, Burma S, Scaglioni PP, Cantley LC, DeBerardinis RJ, Kimmelman AC, Lyssiotis CA, Boothman DA. Targeting glutamine metabolism sensitizes pancreatic cancer to PARP-driven metabolic catastrophe induced by ß-lapachone. Cancer Metab. 2015 Oct 12;3:12. doi: 10.1186/s40170-015-0137-1. eCollection 2015. PMID: 26462257; PMCID: PMC4601138.
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ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update.

Stem cell reports

Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X.
PMID: 34048692
Stem Cell Reports. 2021 Jun 08;16(6):1398-1408. doi: 10.1016/j.stemcr.2021.05.012. Epub 2021 May 27.

The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy...

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Lovell-Badge R, Anthony E, Barker RA, et al. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 2021;16(6):1398-1408doi: 10.1016/j.stemcr.2021.05.012.
Lovell-Badge, R., Anthony, E., Barker, R. A., Bubela, T., Brivanlou, A. H., Carpenter, M., Charo, R. A., Clark, A., Clayton, E., Cong, Y., Daley, G. Q., Fu, J., Fujita, M., Greenfield, A., Goldman, S. A., Hill, L., Hyun, I., Isasi, R., Kahn, J., Kato, K., Kim, J. S., Kimmelman, J., Knoblich, J. A., Mathews, D., Montserrat, N., Mosher, J., Munsie, M., Nakauchi, H., Naldini, L., Naughton, G., Niakan, K., Ogbogu, U., Pedersen, R., Rivron, N., Rooke, H., Rossant, J., Round, J., Saitou, M., Sipp, D., Steffann, J., Sugarman, J., Surani, A., Takahashi, J., Tang, F., Turner, L., Zettler, P. J., & Zhai, X. (2021). ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem cell reports, 16(6), 1398-1408. https://doi.org/10.1016/j.stemcr.2021.05.012
Lovell-Badge, Robin, et al. "ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update." Stem cell reports vol. 16,6 (2021): 1398-1408. doi: https://doi.org/10.1016/j.stemcr.2021.05.012
Lovell-Badge R, Anthony E, Barker RA, Bubela T, Brivanlou AH, Carpenter M, Charo RA, Clark A, Clayton E, Cong Y, Daley GQ, Fu J, Fujita M, Greenfield A, Goldman SA, Hill L, Hyun I, Isasi R, Kahn J, Kato K, Kim JS, Kimmelman J, Knoblich JA, Mathews D, Montserrat N, Mosher J, Munsie M, Nakauchi H, Naldini L, Naughton G, Niakan K, Ogbogu U, Pedersen R, Rivron N, Rooke H, Rossant J, Round J, Saitou M, Sipp D, Steffann J, Sugarman J, Surani A, Takahashi J, Tang F, Turner L, Zettler PJ, Zhai X. ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update. Stem Cell Reports. 2021 Jun 08;16(6):1398-1408. doi: 10.1016/j.stemcr.2021.05.012. Epub 2021 May 27. PMID: 34048692; PMCID: PMC8190668.
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Reply to 'Correcting the ASCO position on phase I clinical trials in cancer'.

Nature reviews. Clinical oncology

Kimmelman J.
PMID: 31857690
Nat Rev Clin Oncol. 2020 Feb;17(2):125-126. doi: 10.1038/s41571-019-0312-3.

No abstract available.

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Kimmelman J. Reply to 'Correcting the ASCO position on phase I clinical trials in cancer'. Nat Rev Clin Oncol. 2020;17(2):125-126doi: 10.1038/s41571-019-0312-3.
Kimmelman, J. (2020). Reply to 'Correcting the ASCO position on phase I clinical trials in cancer'. Nature reviews. Clinical oncology, 17(2), 125-126. https://doi.org/10.1038/s41571-019-0312-3
Kimmelman, Jonathan. "Reply to 'Correcting the ASCO position on phase I clinical trials in cancer'." Nature reviews. Clinical oncology vol. 17,2 (2020): 125-126. doi: https://doi.org/10.1038/s41571-019-0312-3
Kimmelman J. Reply to 'Correcting the ASCO position on phase I clinical trials in cancer'. Nat Rev Clin Oncol. 2020 Feb;17(2):125-126. doi: 10.1038/s41571-019-0312-3. PMID: 31857690.
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Response-Evaluating human trials: FDA's role.

Science (New York, N.Y.)

Shah SK, Kimmelman J, Lyerly AD, Lynch HF, Miller FG, Palacios R, Pardo CA, Zorrilla C.
PMID: 29930129
Science. 2018 Jun 22;360(6395):1308-1309. doi: 10.1126/science.aau0865. Epub 2018 Jun 21.

No abstract available.

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Shah SK, Kimmelman J, Lyerly AD, et al. Response-Evaluating human trials: FDA's role. Science. 2018;360(6395):1308-1309doi: 10.1126/science.aau0865.
Shah, S. K., Kimmelman, J., Lyerly, A. D., Lynch, H. F., Miller, F. G., Palacios, R., Pardo, C. A., & Zorrilla, C. (2018). Response-Evaluating human trials: FDA's role. Science (New York, N.Y.), 360(6395), 1308-1309. https://doi.org/10.1126/science.aau0865
Shah, S K, et al. "Response-Evaluating human trials: FDA's role." Science (New York, N.Y.) vol. 360,6395 (2018): 1308-1309. doi: https://doi.org/10.1126/science.aau0865
Shah SK, Kimmelman J, Lyerly AD, Lynch HF, Miller FG, Palacios R, Pardo CA, Zorrilla C. Response-Evaluating human trials: FDA's role. Science. 2018 Jun 22;360(6395):1308-1309. doi: 10.1126/science.aau0865. Epub 2018 Jun 21. PMID: 29930129.
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The Role of Autophagy in Cancer.

Annual review of cancer biology

Santana-Codina N, Mancias JD, Kimmelman AC.
PMID: 31119201
Annu Rev Cancer Biol. 2017 Mar;1:19-39. doi: 10.1146/annurev-cancerbio-041816-122338.

Autophagy is a highly conserved and regulated process that targets proteins and damaged organelles for lysosomal degradation to maintain cell metabolism, genomic integrity, and cell survival. The role of autophagy in cancer is dynamic and depends, in part, on...

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Santana-Codina N, Mancias JD, Kimmelman AC. The Role of Autophagy in Cancer. Annu Rev Cancer Biol. 2017;1:19-39doi: 10.1146/annurev-cancerbio-041816-122338.
Santana-Codina, N., Mancias, J. D., & Kimmelman, A. C. (2017). The Role of Autophagy in Cancer. Annual review of cancer biology, 119-39. https://doi.org/10.1146/annurev-cancerbio-041816-122338
Santana-Codina, Naiara, et al. "The Role of Autophagy in Cancer." Annual review of cancer biology vol. 1 (2017): 19-39. doi: https://doi.org/10.1146/annurev-cancerbio-041816-122338
Santana-Codina N, Mancias JD, Kimmelman AC. The Role of Autophagy in Cancer. Annu Rev Cancer Biol. 2017 Mar;1:19-39. doi: 10.1146/annurev-cancerbio-041816-122338. PMID: 31119201; PMCID: PMC6527373.
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The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews.

American journal of public health

Razaghizad A, Windle SB, Filion KB, Gore G, Kudrina I, Paraskevopoulos E, Kimmelman J, Martel MO, Eisenberg MJ.
PMID: 34464184
Am J Public Health. 2021 Aug;111(8):1516-1517. doi: 10.2105/AJPH.2021.306306a.

No abstract available.

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Razaghizad A, Windle SB, Filion KB, et al. The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews. Am J Public Health. 2021;111(8):1516-1517doi: 10.2105/AJPH.2021.306306a.
Razaghizad, A., Windle, S. B., Filion, K. B., Gore, G., Kudrina, I., Paraskevopoulos, E., Kimmelman, J., Martel, M. O., & Eisenberg, M. J. (2021). The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews. American journal of public health, 111(8), 1516-1517. https://doi.org/10.2105/AJPH.2021.306306a
Razaghizad, Amir, et al. "The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews." American journal of public health vol. 111,8 (2021): 1516-1517. doi: https://doi.org/10.2105/AJPH.2021.306306a
Razaghizad A, Windle SB, Filion KB, Gore G, Kudrina I, Paraskevopoulos E, Kimmelman J, Martel MO, Eisenberg MJ. The Effect of Overdose Education and Naloxone Distribution: An Umbrella Review of Systematic Reviews. Am J Public Health. 2021 Aug;111(8):1516-1517. doi: 10.2105/AJPH.2021.306306a. PMID: 34464184; PMCID: PMC8489639.
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Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models.

Nature communications

Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Makrigiorgos GM, Kimmelman AC, Wong KK.
PMID: 32273495
Nat Commun. 2020 Apr 09;11(1):1835. doi: 10.1038/s41467-020-15348-z.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Herter-Sprie GS, Korideck H, Christensen CL, et al. Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun. 2020;11(1):1835doi: 10.1038/s41467-020-15348-z.
Herter-Sprie, G. S., Korideck, H., Christensen, C. L., Herter, J. M., Rhee, K., Berbeco, R. I., Bennett, D. G., Akbay, E. A., Kozono, D., Mak, R. H., Makrigiorgos, G. M., Kimmelman, A. C., & Wong, K. K. (2020). Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nature communications, 11(1), 1835. https://doi.org/10.1038/s41467-020-15348-z
Herter-Sprie, Grit S, et al. "Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models." Nature communications vol. 11,1 (2020): 1835. doi: https://doi.org/10.1038/s41467-020-15348-z
Herter-Sprie GS, Korideck H, Christensen CL, Herter JM, Rhee K, Berbeco RI, Bennett DG, Akbay EA, Kozono D, Mak RH, Makrigiorgos GM, Kimmelman AC, Wong KK. Author Correction: Image-guided radiotherapy platform using single nodule conditional lung cancer mouse models. Nat Commun. 2020 Apr 09;11(1):1835. doi: 10.1038/s41467-020-15348-z. PMID: 32273495; PMCID: PMC7145825.
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[No title available]

Clinical trials (London, England)

Kimmelman J.
PMID: 34738471
Clin Trials. 2021 Dec;18(6):645-646. doi: 10.1177/17407745211057186. Epub 2021 Nov 05.

No abstract available.

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Kimmelman J. . Clin Trials. 2021;18(6):645-646doi: 10.1177/17407745211057186.
Kimmelman, J. (2021). . Clinical trials (London, England), 18(6), 645-646. https://doi.org/10.1177/17407745211057186
Kimmelman, Jonathan. "." Clinical trials (London, England) vol. 18,6 (2021): 645-646. doi: https://doi.org/10.1177/17407745211057186
Kimmelman J. . Clin Trials. 2021 Dec;18(6):645-646. doi: 10.1177/17407745211057186. Epub 2021 Nov 05. PMID: 34738471.
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Metabolic Codependencies in the Tumor Microenvironment.

Cancer discovery

Dey P, Kimmelman AC, DePinho RA.
PMID: 33504580
Cancer Discov. 2021 May;11(5):1067-1081. doi: 10.1158/2159-8290.CD-20-1211. Epub 2021 Jan 27.

Metabolic reprogramming enables cancer cell growth, proliferation, and survival. This reprogramming is driven by the combined actions of oncogenic alterations in cancer cells and host cell factors acting on cancer cells in the tumor microenvironment. Cancer cell-intrinsic mechanisms activate...

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Dey P, Kimmelman AC, DePinho RA. Metabolic Codependencies in the Tumor Microenvironment. Cancer Discov. 2021;11(5):1067-1081doi: 10.1158/2159-8290.CD-20-1211.
Dey, P., Kimmelman, A. C., & DePinho, R. A. (2021). Metabolic Codependencies in the Tumor Microenvironment. Cancer discovery, 11(5), 1067-1081. https://doi.org/10.1158/2159-8290.CD-20-1211
Dey, Prasenjit, et al. "Metabolic Codependencies in the Tumor Microenvironment." Cancer discovery vol. 11,5 (2021): 1067-1081. doi: https://doi.org/10.1158/2159-8290.CD-20-1211
Dey P, Kimmelman AC, DePinho RA. Metabolic Codependencies in the Tumor Microenvironment. Cancer Discov. 2021 May;11(5):1067-1081. doi: 10.1158/2159-8290.CD-20-1211. Epub 2021 Jan 27. PMID: 33504580; PMCID: PMC8102306.
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Showing 1 to 12 of 44 entries