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Evaluation and treatment of syncope in infants.

Progress in pediatric cardiology

Kochilas L, Tanel RE.
PMID: 11457676
Prog Pediatr Cardiol. 2001 Aug;13(2):71-82. doi: 10.1016/s1058-9813(01)00090-x.

Syncope in the infant and newborn occurs as a loss of consciousness due to a variety of etiologies. Because syncope at this age may be a harbinger of sudden infant death, the symptom provokes anxiety and challenges clinicians to...

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Kochilas L, Tanel RE. Evaluation and treatment of syncope in infants. Prog Pediatr Cardiol. 2001;13(2):71-82doi: 10.1016/s1058-9813(01)00090-x.
Kochilas, L., & Tanel, R. E. (2001). Evaluation and treatment of syncope in infants. Progress in pediatric cardiology, 13(2), 71-82. https://doi.org/10.1016/s1058-9813(01)00090-x
Kochilas, L, and Tanel, R E.. "Evaluation and treatment of syncope in infants." Progress in pediatric cardiology vol. 13,2 (2001): 71-82. doi: https://doi.org/10.1016/s1058-9813(01)00090-x
Kochilas L, Tanel RE. Evaluation and treatment of syncope in infants. Prog Pediatr Cardiol. 2001 Aug;13(2):71-82. doi: 10.1016/s1058-9813(01)00090-x. PMID: 11457676.
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Fog2 is required for normal diaphragm and lung development in mice and humans.

PLoS genetics

Ackerman KG, Herron BJ, Vargas SO, Huang H, Tevosian SG, Kochilas L, Rao C, Pober BR, Babiuk RP, Epstein JA, Greer JJ, Beier DR.
PMID: 16103912
PLoS Genet. 2005 Jul;1(1):58-65. doi: 10.1371/journal.pgen.0010010. Epub 2005 Jun 17.

Congenital diaphragmatic hernia and other congenital diaphragmatic defects are associated with significant mortality and morbidity in neonates; however, the molecular basis of these developmental anomalies is unknown. In an analysis of E18.5 embryos derived from mice treated with N-ethyl-N-nitrosourea,...

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Ackerman KG, Herron BJ, Vargas SO, et al. Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005;1(1):58-65doi: 10.1371/journal.pgen.0010010.
Ackerman, K. G., Herron, B. J., Vargas, S. O., Huang, H., Tevosian, S. G., Kochilas, L., Rao, C., Pober, B. R., Babiuk, R. P., Epstein, J. A., Greer, J. J., & Beier, D. R. (2005). Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS genetics, 1(1), 58-65. https://doi.org/10.1371/journal.pgen.0010010
Ackerman, Kate G, et al. "Fog2 is required for normal diaphragm and lung development in mice and humans." PLoS genetics vol. 1,1 (2005): 58-65. doi: https://doi.org/10.1371/journal.pgen.0010010
Ackerman KG, Herron BJ, Vargas SO, Huang H, Tevosian SG, Kochilas L, Rao C, Pober BR, Babiuk RP, Epstein JA, Greer JJ, Beier DR. Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005 Jul;1(1):58-65. doi: 10.1371/journal.pgen.0010010. Epub 2005 Jun 17. PMID: 16103912; PMCID: PMC1183529.
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Unusual case of intraluminal cecal recurrence of a low grade appendiceal mucinous neoplasm (LAMN)-Case report and brief literature review.

International journal of surgery case reports

Givalos N, Manolidis G, Kochylas N, Vrachni V, Tsakona S, Eftychiadis C, Vrachnos P.
PMID: 30149327
Int J Surg Case Rep. 2018;51:112-116. doi: 10.1016/j.ijscr.2018.08.032. Epub 2018 Aug 22.

INTRODUCTION: Appendiceal mucinous neoplasms exhibit a wide spectrum of clinical behavior, ranging from neoplasms which are relatively slow-growing but with considerable risk for recurrence and eventual death and those neoplasms that are highly aggressive with increased likelihood of early...

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Givalos N, Manolidis G, Kochylas N, et al. Unusual case of intraluminal cecal recurrence of a low grade appendiceal mucinous neoplasm (LAMN)-Case report and brief literature review. Int J Surg Case Rep. 2018;51:112-116doi: 10.1016/j.ijscr.2018.08.032.
Givalos, N., Manolidis, G., Kochylas, N., Vrachni, V., Tsakona, S., Eftychiadis, C., & Vrachnos, P. (2018). Unusual case of intraluminal cecal recurrence of a low grade appendiceal mucinous neoplasm (LAMN)-Case report and brief literature review. International journal of surgery case reports, 51112-116. https://doi.org/10.1016/j.ijscr.2018.08.032
Givalos, Nick, et al. "Unusual case of intraluminal cecal recurrence of a low grade appendiceal mucinous neoplasm (LAMN)-Case report and brief literature review." International journal of surgery case reports vol. 51 (2018): 112-116. doi: https://doi.org/10.1016/j.ijscr.2018.08.032
Givalos N, Manolidis G, Kochylas N, Vrachni V, Tsakona S, Eftychiadis C, Vrachnos P. Unusual case of intraluminal cecal recurrence of a low grade appendiceal mucinous neoplasm (LAMN)-Case report and brief literature review. Int J Surg Case Rep. 2018;51:112-116. doi: 10.1016/j.ijscr.2018.08.032. Epub 2018 Aug 22. PMID: 30149327; PMCID: PMC6111031.
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Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling.

Pain

Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR, Streicher JM.
PMID: 34252907
Pain. 2022 Jan 01;163(1):146-158. doi: 10.1097/j.pain.0000000000002320.

ABSTRACT: The opioid receptors are important regulators of pain, reward, and addiction. Limited evidence suggests the mu and delta opioid receptors form a heterodimer (MDOR), which may act as a negative feedback brake on opioid-induced analgesia. However, evidence for...

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Keresztes A, Olson K, Nguyen P, et al. Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain. 2022;163(1):146-158doi: 10.1097/j.pain.0000000000002320.
Keresztes, A., Olson, K., Nguyen, P., Lopez-Pier, M. A., Hecksel, R., Barker, N. K., Liu, Z., Hruby, V., Konhilas, J., Langlais, P. R., & Streicher, J. M. (2022). Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain, 163(1), 146-158. https://doi.org/10.1097/j.pain.0000000000002320
Keresztes, Attila, et al. "Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling." Pain vol. 163,1 (2022): 146-158. doi: https://doi.org/10.1097/j.pain.0000000000002320
Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR, Streicher JM. Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain. 2022 Jan 01;163(1):146-158. doi: 10.1097/j.pain.0000000000002320. PMID: 34252907; PMCID: PMC8688156.
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Improved Surface-Enhanced-Raman Scattering Sensitivity Using Si Nanowires/Silver Nanostructures by a Single Step Metal-Assisted Chemical Etching.

Nanomaterials (Basel, Switzerland)

Kochylas I, Gardelis S, Likodimos V, Giannakopoulos KP, Falaras P, Nassiopoulou AG.
PMID: 34361147
Nanomaterials (Basel). 2021 Jul 06;11(7). doi: 10.3390/nano11071760.

In this study, we developed highly sensitive substrates for Surface-Enhanced-Raman-Scattering (SERS) spectroscopy, consisting of silicon nanowires (SiNWs) decorated by silver nanostructures using single-step Metal Assisted Chemical Etching (MACE). One-step MACE was performed on p-type Si substrates by immersion in...

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Kochylas I, Gardelis S, Likodimos V, et al. Improved Surface-Enhanced-Raman Scattering Sensitivity Using Si Nanowires/Silver Nanostructures by a Single Step Metal-Assisted Chemical Etching. Nanomaterials (Basel). 2021;11(7)doi: 10.3390/nano11071760.
Kochylas, I., Gardelis, S., Likodimos, V., Giannakopoulos, K. P., Falaras, P., & Nassiopoulou, A. G. (2021). Improved Surface-Enhanced-Raman Scattering Sensitivity Using Si Nanowires/Silver Nanostructures by a Single Step Metal-Assisted Chemical Etching. Nanomaterials (Basel, Switzerland), 11(7), . https://doi.org/10.3390/nano11071760
Kochylas, Ioannis, et al. "Improved Surface-Enhanced-Raman Scattering Sensitivity Using Si Nanowires/Silver Nanostructures by a Single Step Metal-Assisted Chemical Etching." Nanomaterials (Basel, Switzerland) vol. 11,7 (2021). doi: https://doi.org/10.3390/nano11071760
Kochylas I, Gardelis S, Likodimos V, Giannakopoulos KP, Falaras P, Nassiopoulou AG. Improved Surface-Enhanced-Raman Scattering Sensitivity Using Si Nanowires/Silver Nanostructures by a Single Step Metal-Assisted Chemical Etching. Nanomaterials (Basel). 2021 Jul 06;11(7). doi: 10.3390/nano11071760. PMID: 34361147; PMCID: PMC8308179.
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Epilepsy in children with cerebral palsy: a data linkage study.

Developmental medicine and child neurology

Szpindel A, Myers KA, Ng P, Dorais M, Koclas L, Pigeon N, Shevell M, Oskoui M.
PMID: 34423432
Dev Med Child Neurol. 2021 Aug 22; doi: 10.1111/dmcn.15028. Epub 2021 Aug 22.

AIM: To compare the prevalence of epilepsy in children with cerebral palsy (CP) to peer controls and their differences in healthcare utilization.METHOD: The Quebec CP registry was linked to the provincial administrative health database. Two CP cohorts were identified...

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Szpindel A, Myers KA, Ng P, et al. Epilepsy in children with cerebral palsy: a data linkage study. Dev Med Child Neurol. 2021;doi: 10.1111/dmcn.15028.
Szpindel, A., Myers, K. A., Ng, P., Dorais, M., Koclas, L., Pigeon, N., Shevell, M., & Oskoui, M. (2021). Epilepsy in children with cerebral palsy: a data linkage study. Developmental medicine and child neurology, . https://doi.org/10.1111/dmcn.15028
Szpindel, Aliya, et al. "Epilepsy in children with cerebral palsy: a data linkage study." Developmental medicine and child neurology vol. (2021). doi: https://doi.org/10.1111/dmcn.15028
Szpindel A, Myers KA, Ng P, Dorais M, Koclas L, Pigeon N, Shevell M, Oskoui M. Epilepsy in children with cerebral palsy: a data linkage study. Dev Med Child Neurol. 2021 Aug 22; doi: 10.1111/dmcn.15028. Epub 2021 Aug 22. PMID: 34423432.
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Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns.

Medical devices (Auckland, N.Z.)

Engel MS, Kochilas LK.
PMID: 27468253
Med Devices (Auckl). 2016 Jul 11;9:199-203. doi: 10.2147/MDER.S102146. eCollection 2016.

Congenital heart disease (CHD) is one of the most common birth defects, with an incidence of nine out of every 1,000 live births. The mortality of infants with CHD has decreased over the past 3 decades, but significant morbidity...

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Engel MS, Kochilas LK. Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns. Med Devices (Auckl). 2016;9:199-203doi: 10.2147/MDER.S102146.
Engel, M. S., & Kochilas, L. K. (2016). Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns. Medical devices (Auckland, N.Z.), 9199-203. https://doi.org/10.2147/MDER.S102146
Engel, Melissa S, and Kochilas, Lazaros K. "Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns." Medical devices (Auckland, N.Z.) vol. 9 (2016): 199-203. doi: https://doi.org/10.2147/MDER.S102146
Engel MS, Kochilas LK. Pulse oximetry screening: a review of diagnosing critical congenital heart disease in newborns. Med Devices (Auckl). 2016 Jul 11;9:199-203. doi: 10.2147/MDER.S102146. eCollection 2016. PMID: 27468253; PMCID: PMC4946827.
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Accuracy of administrative claims data for cerebral palsy diagnosis: a retrospective cohort study.

CMAJ open

Oskoui M, Ng P, Dorais M, Pigeon N, Koclas L, Lamarre C, Malouin F, Richards CL, Shevell M, Joseph L.
PMID: 28720597
CMAJ Open. 2017 Jul 18;5(3):E570-E575. doi: 10.9778/cmajo.20170013.

BACKGROUND: Cerebral palsy is the most common cause of childhood physical disability, with multiple associated comorbidities. Administrative claims data provide population-level prevalence estimates for cerebral palsy surveillance; however, their diagnostic accuracy has never been validated in Quebec. This study...

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Oskoui M, Ng P, Dorais M, et al. Accuracy of administrative claims data for cerebral palsy diagnosis: a retrospective cohort study. CMAJ Open. 2017;5(3):E570-E575doi: 10.9778/cmajo.20170013.
Oskoui, M., Ng, P., Dorais, M., Pigeon, N., Koclas, L., Lamarre, C., Malouin, F., Richards, C. L., Shevell, M., & Joseph, L. (2017). Accuracy of administrative claims data for cerebral palsy diagnosis: a retrospective cohort study. CMAJ open, 5(3), E570-E575. https://doi.org/10.9778/cmajo.20170013
Oskoui, Maryam, et al. "Accuracy of administrative claims data for cerebral palsy diagnosis: a retrospective cohort study." CMAJ open vol. 5,3 (2017): E570-E575. doi: https://doi.org/10.9778/cmajo.20170013
Oskoui M, Ng P, Dorais M, Pigeon N, Koclas L, Lamarre C, Malouin F, Richards CL, Shevell M, Joseph L. Accuracy of administrative claims data for cerebral palsy diagnosis: a retrospective cohort study. CMAJ Open. 2017 Jul 18;5(3):E570-E575. doi: 10.9778/cmajo.20170013. PMID: 28720597; PMCID: PMC5621965.
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Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD).

Pulmonary circulation

Schipper DA, Louis AV, Dicken DS, Johnson K, Smolenski RT, Black SM, Runyan R, Konhilas J, Garcia JGN, Khalpey Z.
PMID: 28597777
Pulm Circ. 2017 Apr-Jun;7(2):494-504. doi: 10.1177/2045893217706065. Epub 2017 May 24.

Lungs donated after cardiac death (DCD) are an underutilized resource for a dwindling donor lung transplant pool. Our study investigates the potential of a novel preservation solution, Somah, to better preserve statically stored DCD lungs, for an extended time...

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Schipper DA, Louis AV, Dicken DS, et al. Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD). Pulm Circ. 2017;7(2):494-504doi: 10.1177/2045893217706065.
Schipper, D. A., Louis, A. V., Dicken, D. S., Johnson, K., Smolenski, R. T., Black, S. M., Runyan, R., Konhilas, J., Garcia, J. G. N., & Khalpey, Z. (2017). Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD). Pulmonary circulation, 7(2), 494-504. https://doi.org/10.1177/2045893217706065
Schipper, David A, et al. "Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD)." Pulmonary circulation vol. 7,2 (2017): 494-504. doi: https://doi.org/10.1177/2045893217706065
Schipper DA, Louis AV, Dicken DS, Johnson K, Smolenski RT, Black SM, Runyan R, Konhilas J, Garcia JGN, Khalpey Z. Improved metabolism and redox state with a novel preservation solution: implications for donor lungs after cardiac death (DCD). Pulm Circ. 2017 Apr-Jun;7(2):494-504. doi: 10.1177/2045893217706065. Epub 2017 May 24. PMID: 28597777; PMCID: PMC5467941.
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Reply.

The Journal of pediatrics

Knutson S, Kochilas L.
PMID: 27989410
J Pediatr. 2017 Apr;183:201. doi: 10.1016/j.jpeds.2016.11.061. Epub 2016 Dec 15.

No abstract available.

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Knutson S, Kochilas L. Reply. J Pediatr. 2016;183:201doi: 10.1016/j.jpeds.2016.11.061.
Knutson, S., & Kochilas, L. (2017). Reply. The Journal of pediatrics, 183201. https://doi.org/10.1016/j.jpeds.2016.11.061
Knutson, Stacie, and Kochilas, Lazaros. "Reply." The Journal of pediatrics vol. 183 (2017): 201. doi: https://doi.org/10.1016/j.jpeds.2016.11.061
Knutson S, Kochilas L. Reply. J Pediatr. 2017 Apr;183:201. doi: 10.1016/j.jpeds.2016.11.061. Epub 2016 Dec 15. PMID: 27989410.
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Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling.

Pain

Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR, Streicher JM.
PMID: 34252907
Pain. 2022 Jan 01;163(1):146-158. doi: 10.1097/j.pain.0000000000002320.

ABSTRACT: The opioid receptors are important regulators of pain, reward, and addiction. Limited evidence suggests the mu and delta opioid receptors form a heterodimer (MDOR), which may act as a negative feedback brake on opioid-induced analgesia. However, evidence for...

Cite
Keresztes A, Olson K, Nguyen P, et al. Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain. 2022;163(1):146-158doi: 10.1097/j.pain.0000000000002320.
Keresztes, A., Olson, K., Nguyen, P., Lopez-Pier, M. A., Hecksel, R., Barker, N. K., Liu, Z., Hruby, V., Konhilas, J., Langlais, P. R., & Streicher, J. M. (2022). Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain, 163(1), 146-158. https://doi.org/10.1097/j.pain.0000000000002320
Keresztes, Attila, et al. "Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling." Pain vol. 163,1 (2022): 146-158. doi: https://doi.org/10.1097/j.pain.0000000000002320
Keresztes A, Olson K, Nguyen P, Lopez-Pier MA, Hecksel R, Barker NK, Liu Z, Hruby V, Konhilas J, Langlais PR, Streicher JM. Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling. Pain. 2022 Jan 01;163(1):146-158. doi: 10.1097/j.pain.0000000000002320. PMID: 34252907.
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Thirty-Year Survival after Cardiac Surgery for Patients with Turner Syndrome.

The Journal of pediatrics

Alam S, Claxton JS, Mortillo M, Sassis L, Kefala-Karli P, Silberbach M, Kochilas L, Wechsler SB.
PMID: 34450123
J Pediatr. 2021 Dec;239:187-192.e1. doi: 10.1016/j.jpeds.2021.08.034. Epub 2021 Aug 24.

OBJECTIVE: To evaluate long-term survival in patients with Turner syndrome after congenital heart surgery with a focus on left heart obstructive lesions (LHOLs).STUDY DESIGN: We queried the Pediatric Cardiac Care Consortium, a US-based registry of congenital heart surgery, for...

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Alam S, Claxton JS, Mortillo M, et al. Thirty-Year Survival after Cardiac Surgery for Patients with Turner Syndrome. J Pediatr. 2021;239:187-192.e1doi: 10.1016/j.jpeds.2021.08.034.
Alam, S., Claxton, J. S., Mortillo, M., Sassis, L., Kefala-Karli, P., Silberbach, M., Kochilas, L., & Wechsler, S. B. (2021). Thirty-Year Survival after Cardiac Surgery for Patients with Turner Syndrome. The Journal of pediatrics, 239187-192.e1. https://doi.org/10.1016/j.jpeds.2021.08.034
Alam, Sabikha, et al. "Thirty-Year Survival after Cardiac Surgery for Patients with Turner Syndrome." The Journal of pediatrics vol. 239 (2021): 187-192.e1. doi: https://doi.org/10.1016/j.jpeds.2021.08.034
Alam S, Claxton JS, Mortillo M, Sassis L, Kefala-Karli P, Silberbach M, Kochilas L, Wechsler SB. Thirty-Year Survival after Cardiac Surgery for Patients with Turner Syndrome. J Pediatr. 2021 Dec;239:187-192.e1. doi: 10.1016/j.jpeds.2021.08.034. Epub 2021 Aug 24. PMID: 34450123; PMCID: PMC8626205.
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Showing 1 to 12 of 36 entries