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Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy.

Molecular therapy. Methods & clinical development

Liu L, Lee WS, Doray B, Kornfeld S.
PMID: 28480305
Mol Ther Methods Clin Dev. 2017 Mar 29;5:59-65. doi: 10.1016/j.omtm.2017.03.006. eCollection 2017 Jun 16.

Several lysosomal enzymes currently used for enzyme replacement therapy in patients with lysosomal storage diseases contain very low levels of mannose 6-phosphate, limiting their uptake via mannose 6-phosphate receptors on the surface of the deficient cells. These enzymes are...

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Liu L, Lee WS, Doray B, et al. Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy. Mol Ther Methods Clin Dev. 2017;5:59-65doi: 10.1016/j.omtm.2017.03.006.
Liu, L., Lee, W. S., Doray, B., & Kornfeld, S. (2017). Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy. Molecular therapy. Methods & clinical development, 559-65. https://doi.org/10.1016/j.omtm.2017.03.006
Liu, Lin, et al. "Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy." Molecular therapy. Methods & clinical development vol. 5 (2017): 59-65. doi: https://doi.org/10.1016/j.omtm.2017.03.006
Liu L, Lee WS, Doray B, Kornfeld S. Engineering of GlcNAc-1-Phosphotransferase for Production of Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy. Mol Ther Methods Clin Dev. 2017 Mar 29;5:59-65. doi: 10.1016/j.omtm.2017.03.006. eCollection 2017 Jun 16. PMID: 28480305; PMCID: PMC5415318.
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Remotely Controlled Isomer Selective Molecular Switching.

Nano letters

Schendel V, Borca B, Pentegov I, Michnowicz T, Kraft U, Klauk H, Wahl P, Schlickum U, Kern K.
PMID: 26619213
Nano Lett. 2016 Jan 13;16(1):93-7. doi: 10.1021/acs.nanolett.5b02974. Epub 2015 Dec 04.

Nonlocal addressing-the "remote control"-of molecular switches promises more efficient processing for information technology, where fast speed of switching is essential. The surface state of the (111) facets of noble metals, a confined two-dimensional electron gas, provides a medium that...

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Schendel V, Borca B, Pentegov I, et al. Remotely Controlled Isomer Selective Molecular Switching. Nano Lett. 2015;16(1):93-7doi: 10.1021/acs.nanolett.5b02974.
Schendel, V., Borca, B., Pentegov, I., Michnowicz, T., Kraft, U., Klauk, H., Wahl, P., Schlickum, U., & Kern, K. (2016). Remotely Controlled Isomer Selective Molecular Switching. Nano letters, 16(1), 93-7. https://doi.org/10.1021/acs.nanolett.5b02974
Schendel, Verena, et al. "Remotely Controlled Isomer Selective Molecular Switching." Nano letters vol. 16,1 (2016): 93-7. doi: https://doi.org/10.1021/acs.nanolett.5b02974
Schendel V, Borca B, Pentegov I, Michnowicz T, Kraft U, Klauk H, Wahl P, Schlickum U, Kern K. Remotely Controlled Isomer Selective Molecular Switching. Nano Lett. 2016 Jan 13;16(1):93-7. doi: 10.1021/acs.nanolett.5b02974. Epub 2015 Dec 04. PMID: 26619213.
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Isolation and molecular characterization of Orf virus from natural outbreaks in goats of Assam.

Virusdisease

Bora M, Bora DP, Barman NN, Borah B, Bora PL, Talukdar A, Tamuly S.
PMID: 26436126
Virusdisease. 2015 Jun;26(1):82-8. doi: 10.1007/s13337-015-0255-y. Epub 2015 Jun 23.

Outbreaks of contagious ecthyma (caused by a Parapox virus) in goats were investigated in 6 districts of Assam, a north eastern state of India. Diagnosis of the disease was carried out employing both standard virological as well as molecular...

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Bora M, Bora DP, Barman NN, et al. Isolation and molecular characterization of Orf virus from natural outbreaks in goats of Assam. Virusdisease. 2015;26(1):82-8doi: 10.1007/s13337-015-0255-y.
Bora, M., Bora, D. P., Barman, N. N., Borah, B., Bora, P. L., Talukdar, A., & Tamuly, S. (2015). Isolation and molecular characterization of Orf virus from natural outbreaks in goats of Assam. Virusdisease, 26(1), 82-8. https://doi.org/10.1007/s13337-015-0255-y
Bora, Mousumi, et al. "Isolation and molecular characterization of Orf virus from natural outbreaks in goats of Assam." Virusdisease vol. 26,1 (2015): 82-8. doi: https://doi.org/10.1007/s13337-015-0255-y
Bora M, Bora DP, Barman NN, Borah B, Bora PL, Talukdar A, Tamuly S. Isolation and molecular characterization of Orf virus from natural outbreaks in goats of Assam. Virusdisease. 2015 Jun;26(1):82-8. doi: 10.1007/s13337-015-0255-y. Epub 2015 Jun 23. PMID: 26436126; PMCID: PMC4585050.
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Is kidney function affecting the management of myocardial infarction? A retrospective cohort study in patients with normal kidney function, chronic kidney disease stage III-V, and ESRD.

International journal of nephrology and renovascular disease

Saad M, Karam B, Faddoul G, Douaihy YE, Yacoub H, Baydoun H, Boumitri C, Barakat I, Saifan C, El-Charabaty E, Sayegh SE.
PMID: 26858529
Int J Nephrol Renovasc Dis. 2016 Jan 22;9:5-10. doi: 10.2147/IJNRD.S91567. eCollection 2016.

Patients with chronic kidney disease (CKD) are three times more likely to have myocardial infarction (MI) and suffer from increased morbidity and higher mortality. Traditional and unique risk factors are prevalent and constitute challenges for the standard of care....

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Saad M, Karam B, Faddoul G, et al. Is kidney function affecting the management of myocardial infarction? A retrospective cohort study in patients with normal kidney function, chronic kidney disease stage III-V, and ESRD. Int J Nephrol Renovasc Dis. 2016;9:5-10doi: 10.2147/IJNRD.S91567.
Saad, M., Karam, B., Faddoul, G., Douaihy, Y. E., Yacoub, H., Baydoun, H., Boumitri, C., Barakat, I., Saifan, C., El-Charabaty, E., & Sayegh, S. E. (2016). Is kidney function affecting the management of myocardial infarction? A retrospective cohort study in patients with normal kidney function, chronic kidney disease stage III-V, and ESRD. International journal of nephrology and renovascular disease, 95-10. https://doi.org/10.2147/IJNRD.S91567
Saad, Marc, et al. "Is kidney function affecting the management of myocardial infarction? A retrospective cohort study in patients with normal kidney function, chronic kidney disease stage III-V, and ESRD." International journal of nephrology and renovascular disease vol. 9 (2016): 5-10. doi: https://doi.org/10.2147/IJNRD.S91567
Saad M, Karam B, Faddoul G, Douaihy YE, Yacoub H, Baydoun H, Boumitri C, Barakat I, Saifan C, El-Charabaty E, Sayegh SE. Is kidney function affecting the management of myocardial infarction? A retrospective cohort study in patients with normal kidney function, chronic kidney disease stage III-V, and ESRD. Int J Nephrol Renovasc Dis. 2016 Jan 22;9:5-10. doi: 10.2147/IJNRD.S91567. eCollection 2016. PMID: 26858529; PMCID: PMC4730996.
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Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth.

Data in brief

Anderson JP, Hane JK, Stoll T, Pain N, Hastie ML, Kaur P, Hoogland C, Gorman JJ, Singh KB.
PMID: 27331100
Data Brief. 2016 May 27;8:267-71. doi: 10.1016/j.dib.2016.05.042. eCollection 2016 Sep.

Rhizoctonia solani is an important root infecting pathogen of a range of food staples worldwide including wheat, rice, maize, soybean, potato, legumes and others. Conventional resistance breeding strategies are hindered by the absence of tractable genetic resistance in any...

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Anderson JP, Hane JK, Stoll T, et al. Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth. Data Brief. 2016;8:267-71doi: 10.1016/j.dib.2016.05.042.
Anderson, J. P., Hane, J. K., Stoll, T., Pain, N., Hastie, M. L., Kaur, P., Hoogland, C., Gorman, J. J., & Singh, K. B. (2016). Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth. Data in brief, 8267-71. https://doi.org/10.1016/j.dib.2016.05.042
Anderson, Jonathan P, et al. "Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth." Data in brief vol. 8 (2016): 267-71. doi: https://doi.org/10.1016/j.dib.2016.05.042
Anderson JP, Hane JK, Stoll T, Pain N, Hastie ML, Kaur P, Hoogland C, Gorman JJ, Singh KB. Mass-spectrometry data for Rhizoctonia solani proteins produced during infection of wheat and vegetative growth. Data Brief. 2016 May 27;8:267-71. doi: 10.1016/j.dib.2016.05.042. eCollection 2016 Sep. PMID: 27331100; PMCID: PMC4906030.
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Static-electric-field-induced polarization effects in harmonic generation.

Physical review letters

Borca B, Flegel AV, Frolov MV, Manakov NL, Milosevic DB, Starace AF.
PMID: 10991385
Phys Rev Lett. 2000 Jul 24;85(4):732-5. doi: 10.1103/PhysRevLett.85.732.

Two static-electric-field-induced effects on harmonic generation are demonstrated analytically and numerically: elliptic dichroism (in which the harmonic yield is different for right and left elliptically polarized laser fields) and elliptical polarization of harmonics produced by linearly polarized driving laser...

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Borca B, Flegel AV, Frolov MV, et al. Static-electric-field-induced polarization effects in harmonic generation. Phys Rev Lett. 2000;85(4):732-5doi: 10.1103/PhysRevLett.85.732.
Borca, B., Flegel, A. V., Frolov, M. V., Manakov, N. L., Milosevic, D. B., & Starace, A. F. (2000). Static-electric-field-induced polarization effects in harmonic generation. Physical review letters, 85(4), 732-5. https://doi.org/10.1103/PhysRevLett.85.732
Borca, et al. "Static-electric-field-induced polarization effects in harmonic generation." Physical review letters vol. 85,4 (2000): 732-5. doi: https://doi.org/10.1103/PhysRevLett.85.732
Borca B, Flegel AV, Frolov MV, Manakov NL, Milosevic DB, Starace AF. Static-electric-field-induced polarization effects in harmonic generation. Phys Rev Lett. 2000 Jul 24;85(4):732-5. doi: 10.1103/PhysRevLett.85.732. PMID: 10991385.
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Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue.

Genes & nutrition

Petrović V, Buzadžić B, Korać A, Korać B.
PMID: 20012899
Genes Nutr. 2010 Sep;5(3):225-35. doi: 10.1007/s12263-009-0162-1. Epub 2009 Dec 13.

Cold-exposure activates interscapular brown adipose tissue (IBAT) non-shivering thermogenesis that relies primarily on intensification of metabolic rate and uncoupling. During cold-acclimation, uncoupling in IBAT decreases superoxide (O(2) (·-)) production and as an adaptive response the activities of manganese and...

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Petrović V, Buzadžić B, Korać A, et al. Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue. Genes Nutr. 2009;5(3):225-35doi: 10.1007/s12263-009-0162-1.
Petrović, V., Buzadžić, B., Korać, A., & Korać, B. (2010). Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue. Genes & nutrition, 5(3), 225-35. https://doi.org/10.1007/s12263-009-0162-1
Petrović, Vesna, et al. "Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue." Genes & nutrition vol. 5,3 (2010): 225-35. doi: https://doi.org/10.1007/s12263-009-0162-1
Petrović V, Buzadžić B, Korać A, Korać B. Antioxidative defense and mitochondrial thermogenic response in brown adipose tissue. Genes Nutr. 2010 Sep;5(3):225-35. doi: 10.1007/s12263-009-0162-1. Epub 2009 Dec 13. PMID: 20012899; PMCID: PMC2935534.
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Effect of Holstein-Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility.

Animal : an international journal of animal bioscience

Olmos G, Boyle L, Horan B, Berry DP, Sayers R, Hanlon A, Mee JF.
PMID: 22444820
Animal. 2009 Jul;3(7):1013-24. doi: 10.1017/S1751731109004224.

Pasture-based Holstein-Friesian cows from three genetic groups differing in the Irish 'Economic Breeding Index' (EBI) value and genetic background, namely North-American (NA) national average EBI genetic merit (LOW-NA, n = 42), North-American high EBI genetic merit (HIGH-NA, n =...

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Olmos G, Boyle L, Horan B, et al. Effect of Holstein-Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility. Animal. 2009;3(7):1013-24doi: 10.1017/S1751731109004224.
Olmos, G., Boyle, L., Horan, B., Berry, D. P., Sayers, R., Hanlon, A., & Mee, J. F. (2009). Effect of Holstein-Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility. Animal : an international journal of animal bioscience, 3(7), 1013-24. https://doi.org/10.1017/S1751731109004224
Olmos, G, et al. "Effect of Holstein-Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility." Animal : an international journal of animal bioscience vol. 3,7 (2009): 1013-24. doi: https://doi.org/10.1017/S1751731109004224
Olmos G, Boyle L, Horan B, Berry DP, Sayers R, Hanlon A, Mee JF. Effect of Holstein-Friesian genetic group on peripartum and early lactation haematological and acute phase proteins profiles, health and fertility. Animal. 2009 Jul;3(7):1013-24. doi: 10.1017/S1751731109004224. PMID: 22444820.
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A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital.

Journal of clinical and diagnostic research : JCDR

Thakkar KB, Jain MM, Billa G, Joshi A, Khobragade AA.
PMID: 24551631
J Clin Diagn Res. 2013 Dec;7(12):2759-64. doi: 10.7860/JCDR/2013/6760.3885. Epub 2013 Dec 15.

BACKGROUND: Psychiatric disorders are one of the major causes of morbidity. Development of newer drugs like SSRIs and atypical antipsychotics has altered the treatment paradigms. Various factors like cost of drugs, local paradigms, etc. play a role in the...

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Thakkar KB, Jain MM, Billa G, et al. A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital. J Clin Diagn Res. 2013;7(12):2759-64doi: 10.7860/JCDR/2013/6760.3885.
Thakkar, K. B., Jain, M. M., Billa, G., Joshi, A., & Khobragade, A. A. (2013). A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital. Journal of clinical and diagnostic research : JCDR, 7(12), 2759-64. https://doi.org/10.7860/JCDR/2013/6760.3885
Thakkar, Karan B, et al. "A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital." Journal of clinical and diagnostic research : JCDR vol. 7,12 (2013): 2759-64. doi: https://doi.org/10.7860/JCDR/2013/6760.3885
Thakkar KB, Jain MM, Billa G, Joshi A, Khobragade AA. A drug utilization study of psychotropic drugs prescribed in the psychiatry outpatient department of a tertiary care hospital. J Clin Diagn Res. 2013 Dec;7(12):2759-64. doi: 10.7860/JCDR/2013/6760.3885. Epub 2013 Dec 15. PMID: 24551631; PMCID: PMC3919294.
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Tumor characteristics and metastatic sites may predict bevacizumab efficacy in the first-line treatment of metastatic colorectal cancer.

Molecular and clinical oncology

Varol U, Oktay E, Yildirim M, Surmeli ZG, Dirican A, Meydan N, Karaca B, Karabulut B, Uslu R.
PMID: 24649328
Mol Clin Oncol. 2014 Jan;2(1):166-170. doi: 10.3892/mco.2013.212. Epub 2013 Nov 12.

Colorectal cancer (CRC) is among the most frequently diagnosed cancers and a major cause of cancer-related mortality worldwide. The aim of the present study was to determine whether there was an improvement in the time to disease progression (TTP)...

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Varol U, Oktay E, Yildirim M, et al. Tumor characteristics and metastatic sites may predict bevacizumab efficacy in the first-line treatment of metastatic colorectal cancer. Mol Clin Oncol. 2013;2(1):166-170doi: 10.3892/mco.2013.212.
Varol, U., Oktay, E., Yildirim, M., Surmeli, Z. G., Dirican, A., Meydan, N., Karaca, B., Karabulut, B., & Uslu, R. (2014). Tumor characteristics and metastatic sites may predict bevacizumab efficacy in the first-line treatment of metastatic colorectal cancer. Molecular and clinical oncology, 2(1), 166-170. https://doi.org/10.3892/mco.2013.212
Varol, Umut, et al. "Tumor characteristics and metastatic sites may predict bevacizumab efficacy in the first-line treatment of metastatic colorectal cancer." Molecular and clinical oncology vol. 2,1 (2014): 166-170. doi: https://doi.org/10.3892/mco.2013.212
Varol U, Oktay E, Yildirim M, Surmeli ZG, Dirican A, Meydan N, Karaca B, Karabulut B, Uslu R. Tumor characteristics and metastatic sites may predict bevacizumab efficacy in the first-line treatment of metastatic colorectal cancer. Mol Clin Oncol. 2014 Jan;2(1):166-170. doi: 10.3892/mco.2013.212. Epub 2013 Nov 12. PMID: 24649328; PMCID: PMC3915705.
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Donor-specific Antibodies, Immunoglobulin-free Light Chains, and BAFF Levels in Relation to Risk of Late-onset PTLD in Liver Recipients.

Transplantation direct

Engels EA, Jennings LW, Everly MJ, Landgren O, Murata K, Yanik EL, Pfeiffer RM, Onaca N, Klintmalm GB.
PMID: 30123826
Transplant Direct. 2018 May 15;4(6):e353. doi: 10.1097/TXD.0000000000000792. eCollection 2018 Jun.

BACKGROUND: Posttransplant lymphoproliferative disorder (PTLD) is a neoplastic complication of transplantation, with early cases largely due to immunosuppression and primary Epstein-Barr virus infection. Etiology may differ for later-onset cases, but the contributions of immunosuppression, immune reactivity to the donor...

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Engels EA, Jennings LW, Everly MJ, et al. Donor-specific Antibodies, Immunoglobulin-free Light Chains, and BAFF Levels in Relation to Risk of Late-onset PTLD in Liver Recipients. Transplant Direct. 2018;4(6):e353doi: 10.1097/TXD.0000000000000792.
Engels, E. A., Jennings, L. W., Everly, M. J., Landgren, O., Murata, K., Yanik, E. L., Pfeiffer, R. M., Onaca, N., & Klintmalm, G. B. (2018). Donor-specific Antibodies, Immunoglobulin-free Light Chains, and BAFF Levels in Relation to Risk of Late-onset PTLD in Liver Recipients. Transplantation direct, 4(6), e353. https://doi.org/10.1097/TXD.0000000000000792
Engels, Eric A, et al. "Donor-specific Antibodies, Immunoglobulin-free Light Chains, and BAFF Levels in Relation to Risk of Late-onset PTLD in Liver Recipients." Transplantation direct vol. 4,6 (2018): e353. doi: https://doi.org/10.1097/TXD.0000000000000792
Engels EA, Jennings LW, Everly MJ, Landgren O, Murata K, Yanik EL, Pfeiffer RM, Onaca N, Klintmalm GB. Donor-specific Antibodies, Immunoglobulin-free Light Chains, and BAFF Levels in Relation to Risk of Late-onset PTLD in Liver Recipients. Transplant Direct. 2018 May 15;4(6):e353. doi: 10.1097/TXD.0000000000000792. eCollection 2018 Jun. PMID: 30123826; PMCID: PMC6089512.
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Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials.

Journal of arrhythmia

Pandya B, Spagnola J, Sheikh A, Karam B, Anugu VR, Khan A, Lafferty J, Kenigsberg D, Kowalski M.
PMID: 27354866
J Arrhythm. 2016 Jun;32(3):204-11. doi: 10.1016/j.joa.2016.02.006. Epub 2016 Mar 11.

INTRODUCTION: Anti-arrhythmic medications (AAMs) are known to increase cardiac mortality significantly due to their pro-arrhythmic effects. However, the effect of AAMs on non-cardiac mortality has not been evaluated.METHODS: Trials published in English language journals from 1990 to 2015 were...

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Pandya B, Spagnola J, Sheikh A, et al. Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials. J Arrhythm. 2016;32(3):204-11doi: 10.1016/j.joa.2016.02.006.
Pandya, B., Spagnola, J., Sheikh, A., Karam, B., Anugu, V. R., Khan, A., Lafferty, J., Kenigsberg, D., & Kowalski, M. (2016). Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials. Journal of arrhythmia, 32(3), 204-11. https://doi.org/10.1016/j.joa.2016.02.006
Pandya, Bhavi, et al. "Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials." Journal of arrhythmia vol. 32,3 (2016): 204-11. doi: https://doi.org/10.1016/j.joa.2016.02.006
Pandya B, Spagnola J, Sheikh A, Karam B, Anugu VR, Khan A, Lafferty J, Kenigsberg D, Kowalski M. Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials. J Arrhythm. 2016 Jun;32(3):204-11. doi: 10.1016/j.joa.2016.02.006. Epub 2016 Mar 11. PMID: 27354866; PMCID: PMC4913148.
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Showing 1 to 12 of 266 entries