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Showing 1 to 12 of 27 entries
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Workshop Report on the European Bone Sarcoma Networking Meeting: Integration of Clinical Trials with Tumor Biology.

Journal of adolescent and young adult oncology

Thomas DM, Wilhelm M, Cleton-Jansen AM, Dirksen U, Entz-Werlé N, Gelderblom H, Hassan B, Jürgens H, Koster J, Kovar H, Lankester AC, Lewis IJ, Myklebost O, Nathrath MH, Picci P, Whelan JS, Hogendoorn PC, Bielack SS.
PMID: 26811922
J Adolesc Young Adult Oncol. 2011 Sep;1(3):118-23. doi: 10.1089/jayao.2012.0005.

A key workshop was held in The Netherlands in June 2011, hosted by several European bone sarcoma networks and with a broad range of stakeholders from Europe and Australia. The purpose of the meeting was to identify the strengths...

Malignant phylloides tumor of breast in a pregnant woman with coincidental nulliparous vaginal prolapse.

Iranian journal of medical sciences

Ray S, Basak S, Das S, Pal M, Konar H.
PMID: 23115419
Iran J Med Sci. 2011 Dec;36(4):315-7.

Malignant phylloides tumor is a relatively rare and rapidly growing tumor of the breast. Presentation during pregnancy is uncommon. Reports regarding malignancy in these tumors differ greatly in incidence, and most of them are stromal malignancies. We report this...

The first European interdisciplinary ewing sarcoma research summit.

Frontiers in oncology

Kovar H, Alonso J, Aman P, Aryee DN, Ban J, Burchill SA, Burdach S, De Alava E, Delattre O, Dirksen U, Fourtouna A, Fulda S, Helman LJ, Herrero-Martin D, Hogendoorn PC, Kontny U, Lawlor ER, Lessnick SL, Llombart-Bosch A, Metzler M, Moriggl R, Niedan S, Potratz J, Redini F, Richter GH, Riedmann LT, Rossig C, Schäfer BW, Schwentner R, Scotlandi K, Sorensen PH, Staege MS, Tirode F, Toretsky J, Ventura S, Eggert A, Ladenstein R.
PMID: 22662320
Front Oncol. 2012 May 29;2:54. doi: 10.3389/fonc.2012.00054. eCollection 2012.

The European Network for Cancer Research in Children and Adolescents (ENCCA) provides an interaction platform for stakeholders in research and care of children with cancer. Among ENCCA objectives is the establishment of biology-based prioritization mechanisms for the selection of...

Progress in the molecular biology of ewing tumors.

Sarcoma

Kovar H.
PMID: 18521227
Sarcoma. 1998;2(1):3-17. doi: 10.1080/13577149878109.

Purpose/results/discussion. Rearrangement of the EWS gene with an ETS oncogene by chromosomal translocation is a hallmark of the Ewing family of tumors (EFT). Detectability, incidence, tumor specificity and variability of this aberration have been matters of intense investigation in...

Systematic review of the immunological landscape of Wilms tumors.

Molecular therapy oncolytics

Palmisani F, Kovar H, Kager L, Amann G, Metzelder M, Bergmann M.
PMID: 34553032
Mol Ther Oncolytics. 2021 Jul 13;22:454-467. doi: 10.1016/j.omto.2021.06.016. eCollection 2021 Sep 24.

Results of immunotherapy in childhood solid cancer have been so far, with the exception of neuroblastoma, quite disappointing. Lack of knowledge of the immune contexture of these tumors may have contributed to the failure of immunotherapies so far. Here,...

Chronic disease services in local health departments; report of a survey.

American journal of public health and the nation's health

MULLER JN, KOVAR EB.
PMID: 13403030
Am J Public Health Nations Health. 1957 Mar;47(3):352-62. doi: 10.2105/ajph.47.3.352.

No abstract available.

Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.

Cell death & disease

Javaheri T, Kazemi Z, Pencik J, Pham HTT, Kauer M, Noorizadeh R, Sax B, Nivarthi H, Schlederer M, Maurer B, Hofbauer M, Aryee DNT, Wiedner M, Tomazou EM, Logan M, Hartmann C, Tuckermann JP, Kenner L, Mikula M, Dolznig H, Üren A, Richter GH, Grebien F, Kovar H, Moriggl R.
PMID: 31406155
Cell Death Dis. 2019 Aug 13;10(8):605. doi: 10.1038/s41419-019-1853-1.

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

The molecular basis of sarcoma.

Sarcoma

Lessnick SL, Kovar H, Houghton P.
PMID: 21772794
Sarcoma. 2011;2011:864130. doi: 10.1155/2011/864130. Epub 2011 Jun 07.

No abstract available.

Ewing Sarcoma-Diagnosis, Treatment, Clinical Challenges and Future Perspectives.

Journal of clinical medicine

Zöllner SK, Amatruda JF, Bauer S, Collaud S, de Álava E, DuBois SG, Hardes J, Hartmann W, Kovar H, Metzler M, Shulman DS, Streitbürger A, Timmermann B, Toretsky JA, Uhlenbruch Y, Vieth V, Grünewald TGP, Dirksen U.
PMID: 33919988
J Clin Med. 2021 Apr 14;10(8). doi: 10.3390/jcm10081685.

Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime example of the paradigms of a translocation-positive sarcoma: a genetically rather simple disease with a specific and neomorphic-potential therapeutic target, whose oncogenic role was irrefutably defined...

YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells.

Oncogenesis

Bierbaumer L, Katschnig AM, Radic-Sarikas B, Kauer MO, Petro JA, Högler S, Gurnhofer E, Pedot G, Schäfer BW, Schwentner R, Mühlbacher K, Kromp F, Aryee DNT, Kenner L, Uren A, Kovar H.
PMID: 33419969
Oncogenesis. 2021 Jan 08;10(1):2. doi: 10.1038/s41389-020-00294-8.

Ewing sarcoma (EwS) is a highly metastatic bone cancer characterized by the ETS fusion oncoprotein EWS-FLI1. EwS cells are phenotypically highly plastic and switch between functionally distinct cell states dependent on EWS-FLI1 fluctuations. Whereas EWS-FLI1

Dr. Jekyll and Mr. Hyde: The Two Faces of the FUS/EWS/TAF15 Protein Family.

Sarcoma

Kovar H.
PMID: 21197473
Sarcoma. 2011;2011:837474. doi: 10.1155/2011/837474. Epub 2010 Dec 09.

FUS, EWS, and TAF15 form the FET family of RNA-binding proteins whose genes are found rearranged with various transcription factor genes predominantly in sarcomas and in rare hematopoietic and epithelial cancers. The resulting fusion gene products have attracted considerable...

Pregnancy complicated by maternal heart disease: a review of 281 women.

Journal of obstetrics and gynaecology of India

Konar H, Chaudhuri S.
PMID: 23730034
J Obstet Gynaecol India. 2012 Jun;62(3):301-6. doi: 10.1007/s13224-012-0220-2. Epub 2012 Aug 17.

OBJECTIVES: To study maternal heart disease in an Indian setting for: (1) different etiological factors, (2) different types of lesions, and (3) maternal and perinatal outcome.METHODS: 281 women with heart disease who delivered ≥28 weeks of gestation at different...

Showing 1 to 12 of 27 entries