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Showing 1 to 12 of 27 entries
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Author Correction: Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.

Nature communications

Wilhelm M, Zolg DP, Graber M, Gessulat S, Schmidt T, Schnatbaum K, Schwencke-Westphal C, Seifert P, de Andrade Krätzig N, Zerweck J, Knaute T, Bräunlein E, Samaras P, Lautenbacher L, Klaeger S, Wenschuh H, Rad R, Delanghe B, Huhmer A, Carr SA, Clauser KR, Krackhardt AM, Reimer U, Kuster B.
PMID: 34162890
Nat Commun. 2021 Jun 23;12(1):4002. doi: 10.1038/s41467-021-24263-w.

No abstract available.

Synthesis and Preclinical Evaluation of a .

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Robu S, Richter A, Gosmann D, Seidl C, Leung D, Hayes W, Cohen D, Morin P, Donnelly DJ, Lipovšek D, Bonacorsi SJ, Smith A, Steiger K, Aulehner C, Krackhardt AM, Weber WA.
PMID: 33517324
J Nucl Med. 2021 Sep 01;62(9):1228-1234. doi: 10.2967/jnumed.120.258384. Epub 2021 Jan 30.

Blocking the interaction of the immune checkpoint molecule programmed cell death protein-1 and its ligand, PD-L1, using specific antibodies has been a major breakthrough for immune oncology. Whole-body PD-L1 expression PET imaging may potentially allow for a better prediction...

Adoptive T Cell Therapy Is Complemented by Oncolytic Virotherapy with Fusogenic VSV-NDV in Combination Treatment of Murine Melanoma.

Cancers

Krabbe T, Marek J, Groll T, Steiger K, Schmid RM, Krackhardt AM, Altomonte J.
PMID: 33801359
Cancers (Basel). 2021 Mar 02;13(5). doi: 10.3390/cancers13051044.

Cancer immunotherapies have made major advancements in recent years and are becoming the prevalent treatment options for numerous tumor entities. However, substantial response rates have only been observed in specific subsets of patients since pre-existing factors determine the susceptibility...

Targeting Folates by Carboxypeptidase G2: Potential Applications in Anticancer Therapy.

Onkologie

Krackhardt A, Schwartz S, Thiel E.
PMID: 11441258
Onkologie. 2000 Dec;23(6):538-543. doi: 10.1159/000055003.

Carboxypeptidase G2 (CPG2) cleaves folates and folate analogues resulting in alternative routes of folate metabolism. CPG2 is of particular interest in anticancer therapy for several reasons. CPG2 rapidly converts methotrexate (MTX) into less toxic metabolites causing a rapid decline...

DCB meets DES.

Herz

Krackhardt F, Noutsias M, Tschöpe C, Kherad B.
PMID: 28116465
Herz. 2017 Nov;42(7):696-697. doi: 10.1007/s00059-016-4529-y. Epub 2017 Jan 23.

No abstract available.

Surveillance for parasites in unaccompanied minor refugees migrating to Germany in 2015.

GMS hygiene and infection control

Heudorf U, Karathana M, Krackhardt B, Huber M, Raupp P, Zinn C.
PMID: 26958459
GMS Hyg Infect Control. 2016 Mar 01;11:Doc05. doi: 10.3205/dgkh000265. eCollection 2016.

In 2015, most of the refugees arriving in Germany originated from countries with poor hygienic and sanitary conditions. Stool samples of 1,230 minor refugees unaccompanied by adults were investigated for possible parasites. Giardia lamblia was by far the most...

A Rare Case of Single Coronary Artery with Atherosclerotic Lesions Arising from the Right Sinus of Valsalva.

North American journal of medical sciences

Blaschke F, Krackhardt F, Kherad B, Pieske B, Haverkamp W, Rief M.
PMID: 27042610
N Am J Med Sci. 2016 Feb;8(2):114-6. doi: 10.4103/1947-2714.177345.

CONTEXT: Congenital coronary anomalies, including anomalous origin, distribution, intercoronary communications, and coronary fistulae occur at a rate of approximately 1% in the general population and are the most incidental findings.CASE REPORT: A 49-year-old male patient presented to the emergency...

Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma.

Journal for immunotherapy of cancer

Bräunlein E, Lupoli G, Füchsl F, Abualrous ET, de Andrade Krätzig N, Gosmann D, Wietbrock L, Lange S, Engleitner T, Lan H, Audehm S, Effenberger M, Boxberg M, Steiger K, Chang Y, Yu K, Atay C, Bassermann F, Weichert W, Busch DH, Rad R, Freund C, Antes I, Krackhardt AM.
PMID: 34518289
J Immunother Cancer. 2021 Sep;9(9). doi: 10.1136/jitc-2021-002754.

BACKGROUND: Neoantigens derived from somatic mutations correlate with therapeutic responses mediated by treatment with immune checkpoint inhibitors. Neoantigens are therefore highly attractive targets for the development of therapeutic approaches in personalized medicine, although many aspects of their quality and...

Patient with heart failure: importance to treat valvular diseases.

European heart journal supplements : journal of the European Society of Cardiology

Adamo M, Alos B, Metra M, Lefèvre T, Swaans MJ, Gheorghe L, Tschöpe C, Krackhardt F, Alfieri O, Bouleti C.
PMID: 33390869
Eur Heart J Suppl. 2020 Dec 23;22:P38-P41. doi: 10.1093/eurheartj/suaa184. eCollection 2020 Dec.

COVID-19 pandemic is causing an unprecedented burden on healthcare resources and this includes treatment of heart failure and valvular heart diseases (VHD). Percutaneous procedures have broadened the number of patients with VHD who could be treated. However, COVID-19 pandemic...

Cycling of redox-sensitive trace metals in barrier island freshwater lenses.

The Science of the total environment

Reckhardt A, Seibert SL, Holt T, Ahrens J, Beck M, Massmann G, Brumsack HJ.
PMID: 33736321
Sci Total Environ. 2021 May 10;768:144964. doi: 10.1016/j.scitotenv.2021.144964. Epub 2021 Jan 30.

Freshwater lenses connect the terrestrial and marine realm via groundwater discharge at the edges of islands and serve as drinking water resources. We studied the redox-sensitive metals U, Mo, V, and Tl along the redox gradient of fresh groundwater...

Sensitivity of MRQAP Tests to Collinearity and Autocorrelation Conditions.

Psychometrika

Dekker D, Krackhardt D, Snijders TA.
PMID: 20084106
Psychometrika. 2007 Dec;72(4):563-581. doi: 10.1007/s11336-007-9016-1. Epub 2007 Aug 07.

Multiple regression quadratic assignment procedures (MRQAP) tests are permutation tests for multiple linear regression model coefficients for data organized in square matrices of relatedness among n objects. Such a data structure is typical in social network studies, where variables...

Upper bound on the diffraction efficiency of phase-only fanout elements.

Applied optics

Krackhardt U, Mait JN, Streibl N.
PMID: 20717367
Appl Opt. 1992 Jan 01;31(1):27-37. doi: 10.1364/AO.31.000027.

For one-dimensional binary-phase [(0, pi) and (0, non-pi)] fanout elements and for one-dimensional continuous or multilevel quantized phase fanout elements, an upper bound on diffraction efficiency is presented for fanouts ranging from 2 to 25. The upper bound is...

Showing 1 to 12 of 27 entries