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Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study.

Diabetes therapy : research, treatment and education of diabetes and related disorders

Katakami N, Mita T, Yoshii H, Shiraiwa T, Yasuda T, Okada Y, Umayahara Y, Kaneto H, Osonoi T, Yamamoto T, Kuribayashi N, Maeda K, Yokoyama H, Kosugi K, Ohtoshi K, Hayashi I, Sumitani S, Tsugawa M, Ohashi M, Taki H, Nakamura T, Kawashima S, Sato Y, Watada H, Shimomura I.
PMID: 28864997
Diabetes Ther. 2017 Oct;8(5):999-1013. doi: 10.1007/s13300-017-0292-1. Epub 2017 Sep 01.

INTRODUCTION: Sodium-glucose co-transporter-2 (SGLT2) inhibitors are anti-diabetic agents that improve glycemic control with a low risk of hypoglycemia and ameliorate a variety of cardiovascular risk factors. The aim of the ongoing study described herein is to investigate the preventive...

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Katakami N, Mita T, Yoshii H, et al. Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study. Diabetes Ther. 2017;8(5):999-1013doi: 10.1007/s13300-017-0292-1.
Katakami, N., Mita, T., Yoshii, H., Shiraiwa, T., Yasuda, T., Okada, Y., Umayahara, Y., Kaneto, H., Osonoi, T., Yamamoto, T., Kuribayashi, N., Maeda, K., Yokoyama, H., Kosugi, K., Ohtoshi, K., Hayashi, I., Sumitani, S., Tsugawa, M., Ohashi, M., Taki, H., Nakamura, T., Kawashima, S., Sato, Y., Watada, H., Shimomura, I. (2017). Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study. Diabetes therapy : research, treatment and education of diabetes and related disorders, 8(5), 999-1013. https://doi.org/10.1007/s13300-017-0292-1
Katakami, Naoto, et al. "Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study." Diabetes therapy : research, treatment and education of diabetes and related disorders vol. 8,5 (2017): 999-1013. doi: https://doi.org/10.1007/s13300-017-0292-1
Katakami N, Mita T, Yoshii H, Shiraiwa T, Yasuda T, Okada Y, Umayahara Y, Kaneto H, Osonoi T, Yamamoto T, Kuribayashi N, Maeda K, Yokoyama H, Kosugi K, Ohtoshi K, Hayashi I, Sumitani S, Tsugawa M, Ohashi M, Taki H, Nakamura T, Kawashima S, Sato Y, Watada H, Shimomura I. Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study. Diabetes Ther. 2017 Oct;8(5):999-1013. doi: 10.1007/s13300-017-0292-1. Epub 2017 Sep 01. PMID: 28864997; PMCID: PMC5630549.
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Diagnostic relevance of autoantibody detection against inhibitors of apoptosis proteins in colon cancer and colon adenoma.

Molecular and clinical oncology

Hosono Y, Goto M, Kobayashi D, Kuribayashi K, Tanaka M, Watanabe N.
PMID: 26137273
Mol Clin Oncol. 2015 May;3(3):595-600. doi: 10.3892/mco.2015.502. Epub 2015 Feb 06.

Autoantibodies against cancer-related antigens may be detected in the sera of patients with various types of cancer, although their clinical utility has not yet been established. In this study, we aimed to demonstrate the diagnostic relevance of autoantibody detection...

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Hosono Y, Goto M, Kobayashi D, et al. Diagnostic relevance of autoantibody detection against inhibitors of apoptosis proteins in colon cancer and colon adenoma. Mol Clin Oncol. 2015;3(3):595-600doi: 10.3892/mco.2015.502.
Hosono, Y., Goto, M., Kobayashi, D., Kuribayashi, K., Tanaka, M., & Watanabe, N. (2015). Diagnostic relevance of autoantibody detection against inhibitors of apoptosis proteins in colon cancer and colon adenoma. Molecular and clinical oncology, 3(3), 595-600. https://doi.org/10.3892/mco.2015.502
Hosono, Yukie, et al. "Diagnostic relevance of autoantibody detection against inhibitors of apoptosis proteins in colon cancer and colon adenoma." Molecular and clinical oncology vol. 3,3 (2015): 595-600. doi: https://doi.org/10.3892/mco.2015.502
Hosono Y, Goto M, Kobayashi D, Kuribayashi K, Tanaka M, Watanabe N. Diagnostic relevance of autoantibody detection against inhibitors of apoptosis proteins in colon cancer and colon adenoma. Mol Clin Oncol. 2015 May;3(3):595-600. doi: 10.3892/mco.2015.502. Epub 2015 Feb 06. PMID: 26137273; PMCID: PMC4471536.
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A Prospective Epidemiological Study of Injuries in Japanese National Tournament-Level Badminton Players From Junior High School to University.

Asian journal of sports medicine

Miyake E, Yatsunami M, Kurabayashi J, Teruya K, Sekine Y, Endo T, Nishida R, Takano N, Sato S, Jae Kyung H.
PMID: 27217933
Asian J Sports Med. 2016 Mar 01;7(1):e29637. doi: 10.5812/asjsm.29637. eCollection 2016 Mar.

BACKGROUND: Injury prevention programs have recently been created for various sports. However, a longitudinal study on badminton injuries, as assessed by a team's dedicated medical staff, at the gymnasium has not been performed.OBJECTIVES: We aimed to perform the first...

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Miyake E, Yatsunami M, Kurabayashi J, et al. A Prospective Epidemiological Study of Injuries in Japanese National Tournament-Level Badminton Players From Junior High School to University. Asian J Sports Med. 2016;7(1):e29637doi: 10.5812/asjsm.29637.
Miyake, E., Yatsunami, M., Kurabayashi, J., Teruya, K., Sekine, Y., Endo, T., Nishida, R., Takano, N., Sato, S., & Jae Kyung, H. (2016). A Prospective Epidemiological Study of Injuries in Japanese National Tournament-Level Badminton Players From Junior High School to University. Asian journal of sports medicine, 7(1), e29637. https://doi.org/10.5812/asjsm.29637
Miyake, Eiji, et al. "A Prospective Epidemiological Study of Injuries in Japanese National Tournament-Level Badminton Players From Junior High School to University." Asian journal of sports medicine vol. 7,1 (2016): e29637. doi: https://doi.org/10.5812/asjsm.29637
Miyake E, Yatsunami M, Kurabayashi J, Teruya K, Sekine Y, Endo T, Nishida R, Takano N, Sato S, Jae Kyung H. A Prospective Epidemiological Study of Injuries in Japanese National Tournament-Level Badminton Players From Junior High School to University. Asian J Sports Med. 2016 Mar 01;7(1):e29637. doi: 10.5812/asjsm.29637. eCollection 2016 Mar. PMID: 27217933; PMCID: PMC4870827.
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Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity.

World journal of transplantation

Hori T, Kuribayashi K, Saito K, Wang L, Torii M, Uemoto S, Iida T, Yagi S, Kato T.
PMID: 25815267
World J Transplant. 2015 Mar 24;5(1):11-8. doi: 10.5500/wjt.v5.i1.11.

After the first observation of the immunosuppressive effects of ultraviolet (UV) irradiation was reported in 1974, therapeutic modification of immune responses by UV irradiation began to be investigated in the context immunization. UV-induced immunosuppression is via the action of...

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Hori T, Kuribayashi K, Saito K, et al. Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity. World J Transplant. 2015;5(1):11-8doi: 10.5500/wjt.v5.i1.11.
Hori, T., Kuribayashi, K., Saito, K., Wang, L., Torii, M., Uemoto, S., Iida, T., Yagi, S., & Kato, T. (2015). Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity. World journal of transplantation, 5(1), 11-8. https://doi.org/10.5500/wjt.v5.i1.11
Hori, Tomohide, et al. "Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity." World journal of transplantation vol. 5,1 (2015): 11-8. doi: https://doi.org/10.5500/wjt.v5.i1.11
Hori T, Kuribayashi K, Saito K, Wang L, Torii M, Uemoto S, Iida T, Yagi S, Kato T. Ultraviolet-induced alloantigen-specific immunosuppression in transplant immunity. World J Transplant. 2015 Mar 24;5(1):11-8. doi: 10.5500/wjt.v5.i1.11. PMID: 25815267; PMCID: PMC4371157.
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Complete Genome Sequence of Multidrug-Resistant .

Genome announcements

Sato T, Ohkoshi Y, Wada T, Fukushima Y, Murabayashi H, Takakuwa Y, Nishiyama K, Shiraishi T, Nakajima C, Suzuki Y, Yokota SI.
PMID: 29097473
Genome Announc. 2017 Nov 02;5(44). doi: 10.1128/genomeA.01239-17.

Invasive infection of multidrug-resistant

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Sato T, Ohkoshi Y, Wada T, et al. Complete Genome Sequence of Multidrug-Resistant . Genome Announc. 2017;5(44)doi: 10.1128/genomeA.01239-17.
Sato, T., Ohkoshi, Y., Wada, T., Fukushima, Y., Murabayashi, H., Takakuwa, Y., Nishiyama, K., Shiraishi, T., Nakajima, C., Suzuki, Y., & Yokota, S. I. (2017). Complete Genome Sequence of Multidrug-Resistant . Genome announcements, 5(44), . https://doi.org/10.1128/genomeA.01239-17
Sato, Toyotaka, et al. "Complete Genome Sequence of Multidrug-Resistant ." Genome announcements vol. 5,44 (2017). doi: https://doi.org/10.1128/genomeA.01239-17
Sato T, Ohkoshi Y, Wada T, Fukushima Y, Murabayashi H, Takakuwa Y, Nishiyama K, Shiraishi T, Nakajima C, Suzuki Y, Yokota SI. Complete Genome Sequence of Multidrug-Resistant . Genome Announc. 2017 Nov 02;5(44). doi: 10.1128/genomeA.01239-17. PMID: 29097473; PMCID: PMC5668549.
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Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs.

Results in immunology

Kikuchi H, Nakayama M, Takami Y, Kuribayashi F, Nakayama T.
PMID: 24371557
Results Immunol. 2011 Nov 12;1(1):88-94. doi: 10.1016/j.rinim.2011.11.002. eCollection 2011.

The transcription factor Ikaros family consists of five zinc-finger proteins: Ikaros, Aiolos, Helios, Eos and Pegasus; these proteins except Pegasus are essential for development and differentiation of lymphocytes. However, in B lymphocytes, the physiological role of Helios remains to...

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Kikuchi H, Nakayama M, Takami Y, et al. Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs. Results Immunol. 2011;1(1):88-94doi: 10.1016/j.rinim.2011.11.002.
Kikuchi, H., Nakayama, M., Takami, Y., Kuribayashi, F., & Nakayama, T. (2011). Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs. Results in immunology, 1(1), 88-94. https://doi.org/10.1016/j.rinim.2011.11.002
Kikuchi, Hidehiko, et al. "Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs." Results in immunology vol. 1,1 (2011): 88-94. doi: https://doi.org/10.1016/j.rinim.2011.11.002
Kikuchi H, Nakayama M, Takami Y, Kuribayashi F, Nakayama T. Possible involvement of Helios in controlling the immature B cell functions via transcriptional regulation of protein kinase Cs. Results Immunol. 2011 Nov 12;1(1):88-94. doi: 10.1016/j.rinim.2011.11.002. eCollection 2011. PMID: 24371557; PMCID: PMC3787723.
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Estimation of HbA1c response to sitagliptin by change in glycated albumin level for 2 weeks.

Journal of diabetes investigation

Hamaguchi T, Koga M, Murai J, Saito H, Tamada D, Kurebayashi S, Katsuno T, Miyagawa J, Namba M.
PMID: 24843562
J Diabetes Investig. 2012 Mar 28;3(2):175-8. doi: 10.1111/j.2040-1124.2011.00167.x.

UNLABELLED: Aims/Introduction:  Since glycated albumin (GA) reflects shorter-term (about 2 weeks) control of plasma glucose levels compared with HbA1c, GA is thought to be a useful glycemic control indicator for the early period following commencement of the treatment of...

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Hamaguchi T, Koga M, Murai J, et al. Estimation of HbA1c response to sitagliptin by change in glycated albumin level for 2 weeks. J Diabetes Investig. 2012;3(2):175-8doi: 10.1111/j.2040-1124.2011.00167.x.
Hamaguchi, T., Koga, M., Murai, J., Saito, H., Tamada, D., Kurebayashi, S., Katsuno, T., Miyagawa, J., & Namba, M. (2012). Estimation of HbA1c response to sitagliptin by change in glycated albumin level for 2 weeks. Journal of diabetes investigation, 3(2), 175-8. https://doi.org/10.1111/j.2040-1124.2011.00167.x
Hamaguchi, Tomoya, et al. "Estimation of HbA1c response to sitagliptin by change in glycated albumin level for 2 weeks." Journal of diabetes investigation vol. 3,2 (2012): 175-8. doi: https://doi.org/10.1111/j.2040-1124.2011.00167.x
Hamaguchi T, Koga M, Murai J, Saito H, Tamada D, Kurebayashi S, Katsuno T, Miyagawa J, Namba M. Estimation of HbA1c response to sitagliptin by change in glycated albumin level for 2 weeks. J Diabetes Investig. 2012 Mar 28;3(2):175-8. doi: 10.1111/j.2040-1124.2011.00167.x. PMID: 24843562; PMCID: PMC4020736.
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An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan.

Animals : an open access journal from MDPI

Igawa T, Sugawara H, Tado M, Nishitani T, Kurabayashi A, Islam MM, Oumi S, Katsuren S, Fujii T, Sumida M.
PMID: 26479528
Animals (Basel). 2013 Jul 31;3(3):680-92. doi: 10.3390/ani3030680.

Anderson's crocodile newt (Echinotriton andersoni) is distributed in the Central Ryukyu Islands of southern Japan, but environmental degradation and illegal collection over the last several decades have devastated the local populations. It has therefore been listed as a class...

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Igawa T, Sugawara H, Tado M, et al. An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan. Animals (Basel). 2013;3(3):680-92doi: 10.3390/ani3030680.
Igawa, T., Sugawara, H., Tado, M., Nishitani, T., Kurabayashi, A., Islam, M. M., Oumi, S., Katsuren, S., Fujii, T., & Sumida, M. (2013). An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan. Animals : an open access journal from MDPI, 3(3), 680-92. https://doi.org/10.3390/ani3030680
Igawa, Takeshi, et al. "An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan." Animals : an open access journal from MDPI vol. 3,3 (2013): 680-92. doi: https://doi.org/10.3390/ani3030680
Igawa T, Sugawara H, Tado M, Nishitani T, Kurabayashi A, Islam MM, Oumi S, Katsuren S, Fujii T, Sumida M. An Attempt at Captive Breeding of the Endangered Newt Echinotriton andersoni, from the Central Ryukyus in Japan. Animals (Basel). 2013 Jul 31;3(3):680-92. doi: 10.3390/ani3030680. PMID: 26479528; PMCID: PMC4494449.
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Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic .

Frontiers in microbiology

Kurabayashi K, Tanimoto K, Tomita H, Hirakawa H.
PMID: 28360903
Front Microbiol. 2017 Mar 16;8:426. doi: 10.3389/fmicb.2017.00426. eCollection 2017.

Bacterial infections to anaerobic site are often hard to be treated because the activity of most of antimicrobials decreases under anaerobic conditions. However, fosfomycin rather provides a greater activity under anaerobic conditions than aerobic conditions. Previously, we found that...

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Kurabayashi K, Tanimoto K, Tomita H, et al. Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Front Microbiol. 2017;8:426doi: 10.3389/fmicb.2017.00426.
Kurabayashi, K., Tanimoto, K., Tomita, H., & Hirakawa, H. (2017). Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Frontiers in microbiology, 8426. https://doi.org/10.3389/fmicb.2017.00426
Kurabayashi, Kumiko, et al. "Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic ." Frontiers in microbiology vol. 8 (2017): 426. doi: https://doi.org/10.3389/fmicb.2017.00426
Kurabayashi K, Tanimoto K, Tomita H, Hirakawa H. Cooperative Actions of CRP-cAMP and FNR Increase the Fosfomycin Susceptibility of Enterohaemorrhagic . Front Microbiol. 2017 Mar 16;8:426. doi: 10.3389/fmicb.2017.00426. eCollection 2017. PMID: 28360903; PMCID: PMC5352689.
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Post-exercise diastolic stunning detected by velocity vector imaging is a useful marker for induced ischemia in ischemic heart disease.

Journal of echocardiography

Kurosawa K, Watanabe H, Aikawa M, Mihara H, Iguchi N, Asano R, Umemura J, Kurabayashi M, Sumiyoshi T.
PMID: 27278511
J Echocardiogr. 2013 Jun;11(2):50-8. doi: 10.1007/s12574-012-0163-8. Epub 2013 Jan 25.

BACKGROUND: Recently, post-exercise diastolic stunning (PES) has been reported as a new clinical marker of induced ischemia. Velocity vector imaging (VVI) has been developed to visualize regional wall motion abnormalities based on vectors detected by the tissue tracking technique,...

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Kurosawa K, Watanabe H, Aikawa M, et al. Post-exercise diastolic stunning detected by velocity vector imaging is a useful marker for induced ischemia in ischemic heart disease. J Echocardiogr. 2013;11(2):50-8doi: 10.1007/s12574-012-0163-8.
Kurosawa, K., Watanabe, H., Aikawa, M., Mihara, H., Iguchi, N., Asano, R., Umemura, J., Kurabayashi, M., & Sumiyoshi, T. (2013). Post-exercise diastolic stunning detected by velocity vector imaging is a useful marker for induced ischemia in ischemic heart disease. Journal of echocardiography, 11(2), 50-8. https://doi.org/10.1007/s12574-012-0163-8
Kurosawa, Koji, et al. "Post-exercise diastolic stunning detected by velocity vector imaging is a useful marker for induced ischemia in ischemic heart disease." Journal of echocardiography vol. 11,2 (2013): 50-8. doi: https://doi.org/10.1007/s12574-012-0163-8
Kurosawa K, Watanabe H, Aikawa M, Mihara H, Iguchi N, Asano R, Umemura J, Kurabayashi M, Sumiyoshi T. Post-exercise diastolic stunning detected by velocity vector imaging is a useful marker for induced ischemia in ischemic heart disease. J Echocardiogr. 2013 Jun;11(2):50-8. doi: 10.1007/s12574-012-0163-8. Epub 2013 Jan 25. PMID: 27278511.
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Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon.

Physical review letters

Rikanati A, Sadot O, Ben-Dor G, Shvarts D, Kuribayashi T, Takayama K.
PMID: 16712303
Phys Rev Lett. 2006 May 05;96(17):174503. doi: 10.1103/PhysRevLett.96.174503. Epub 2006 May 03.

Theoretical and experimental research, on the previously unresolved instability occurring along the slip stream of a shock-wave Mach reflection, is presented. Growth rates of the large-scale Kelvin-Helmholtz shear flow instability are used to model the evolution of the slip-stream...

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Rikanati A, Sadot O, Ben-Dor G, et al. Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon. Phys Rev Lett. 2006;96(17):174503doi: 10.1103/PhysRevLett.96.174503.
Rikanati, A., Sadot, O., Ben-Dor, G., Shvarts, D., Kuribayashi, T., & Takayama, K. (2006). Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon. Physical review letters, 96(17), 174503. https://doi.org/10.1103/PhysRevLett.96.174503
Rikanati, A, et al. "Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon." Physical review letters vol. 96,17 (2006): 174503. doi: https://doi.org/10.1103/PhysRevLett.96.174503
Rikanati A, Sadot O, Ben-Dor G, Shvarts D, Kuribayashi T, Takayama K. Shock-wave mach-reflection slip-stream instability: a secondary small-scale turbulent mixing phenomenon. Phys Rev Lett. 2006 May 05;96(17):174503. doi: 10.1103/PhysRevLett.96.174503. Epub 2006 May 03. PMID: 16712303.
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Imaging of epithelial cancer in sub-terahertz electromagnetic wave.

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference

Mitobe K, Manabe M, Yoshimura N, Kurabayashi T.
PMID: 17282146
Conf Proc IEEE Eng Med Biol Soc. 2005;2006:199-200. doi: 10.1109/IEMBS.2005.1616377.

We used sub-terahertz (THz) imaging to exam two cross sections of epithelial cancer tissue embedded in paraffin using a 0.19 THz electromagnetic wave. The sub-THz imaging system was constructed with a tunnel injection transit time (TUNNETT) diode, a Schottky...

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Mitobe K, Manabe M, Yoshimura N, et al. Imaging of epithelial cancer in sub-terahertz electromagnetic wave. Conf Proc IEEE Eng Med Biol Soc. 2005;2006:199-200doi: 10.1109/IEMBS.2005.1616377.
Mitobe, K., Manabe, M., Yoshimura, N., & Kurabayashi, T. (2005). Imaging of epithelial cancer in sub-terahertz electromagnetic wave. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2006199-200. https://doi.org/10.1109/IEMBS.2005.1616377
Mitobe, Kazutaka, et al. "Imaging of epithelial cancer in sub-terahertz electromagnetic wave." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference vol. 2006 (2005): 199-200. doi: https://doi.org/10.1109/IEMBS.2005.1616377
Mitobe K, Manabe M, Yoshimura N, Kurabayashi T. Imaging of epithelial cancer in sub-terahertz electromagnetic wave. Conf Proc IEEE Eng Med Biol Soc. 2005;2006:199-200. doi: 10.1109/IEMBS.2005.1616377. PMID: 17282146.
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