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Showing 1 to 12 of 13 entries
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Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis.

Hepatology (Baltimore, Md.)

Yang Z, Zhang T, Kusumanchi P, Tang Q, Sun Z, Radaeva S, Peiffer B, Shah VH, Kamath P, Gores GJ, Sanyal A, Chalasani N, Jiang Y, Huda N, Ma J, Liangpunsakul S.
PMID: 34096637
Hepatology. 2021 Nov;74(5):2436-2451. doi: 10.1002/hep.31994. Epub 2021 Jul 26.

BACKGROUND AND AIMS: We conducted a comprehensive serum transcriptomic analysis to explore the roles of microRNAs (miRNAs) in alcohol-associated hepatitis (AH) pathogenesis and their prognostic significance.APPROACH AND RESULTS: Serum miRNA profiling was performed in 15 controls, 20 heavy drinkers...

Cite
Yang Z, Zhang T, Kusumanchi P, et al. Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology. 2021;74(5):2436-2451doi: 10.1002/hep.31994.
Yang, Z., Zhang, T., Kusumanchi, P., Tang, Q., Sun, Z., Radaeva, S., Peiffer, B., Shah, V. H., Kamath, P., Gores, G. J., Sanyal, A., Chalasani, N., Jiang, Y., Huda, N., Ma, J., & Liangpunsakul, S. (2021). Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology (Baltimore, Md.), 74(5), 2436-2451. https://doi.org/10.1002/hep.31994
Yang, Zhihong, et al. "Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis." Hepatology (Baltimore, Md.) vol. 74,5 (2021): 2436-2451. doi: https://doi.org/10.1002/hep.31994
Yang Z, Zhang T, Kusumanchi P, Tang Q, Sun Z, Radaeva S, Peiffer B, Shah VH, Kamath P, Gores GJ, Sanyal A, Chalasani N, Jiang Y, Huda N, Ma J, Liangpunsakul S. Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology. 2021 Nov;74(5):2436-2451. doi: 10.1002/hep.31994. Epub 2021 Jul 26. PMID: 34096637; PMCID: PMC8542623.
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Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study.

Translational research : the journal of laboratory and clinical medicine

Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S.
PMID: 34743014
Transl Res. 2021 Nov 03; doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03.

Appropriate screening tool for excessive alcohol use (EAU) is clinically important as it may help providers encourage early intervention and prevent adverse outcomes. We hypothesized that patients with excessive alcohol use will have distinct serum metabolites when compared to...

Cite
Liu D, Yang Z, Chandler K, et al. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2021;doi: 10.1016/j.trsl.2021.10.008.
Liu, D., Yang, Z., Chandler, K., Oshodi, A., Zhang, T., Ma, J., Kusumanchi, P., Huda, N., Heathers, L., Perez, K., Tyler, K., Ross, R. A., Jiang, Y., Zhang, D., Zhang, M., & Liangpunsakul, S. (2021). Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Translational research : the journal of laboratory and clinical medicine, . https://doi.org/10.1016/j.trsl.2021.10.008
Liu, Danni, et al. "Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study." Translational research : the journal of laboratory and clinical medicine vol. (2021). doi: https://doi.org/10.1016/j.trsl.2021.10.008
Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2021 Nov 03; doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03. PMID: 34743014.
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Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling.

Hepatology (Baltimore, Md.)

Kusumanchi P, Liang T, Zhang T, Ross RA, Han S, Chandler K, Oshodi A, Jiang Y, Dent AL, Skill NJ, Huda N, Ma J, Yang Z, Liangpunsakul S.
PMID: 33710653
Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30.

BACKGROUND AND AIMS: Chronic alcohol drinking is a major risk factor for alcohol-associated liver disease (ALD). FK506-binding protein 51 (FKBP5), a cochaperone protein, is involved in many key regulatory pathways. It is known to be involved in stress-related disorders,...

Cite
Kusumanchi P, Liang T, Zhang T, et al. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology. 2021;74(3):1234-1250doi: 10.1002/hep.31800.
Kusumanchi, P., Liang, T., Zhang, T., Ross, R. A., Han, S., Chandler, K., Oshodi, A., Jiang, Y., Dent, A. L., Skill, N. J., Huda, N., Ma, J., Yang, Z., & Liangpunsakul, S. (2021). Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology (Baltimore, Md.), 74(3), 1234-1250. https://doi.org/10.1002/hep.31800
Kusumanchi, Praveen, et al. "Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling." Hepatology (Baltimore, Md.) vol. 74,3 (2021): 1234-1250. doi: https://doi.org/10.1002/hep.31800
Kusumanchi P, Liang T, Zhang T, Ross RA, Han S, Chandler K, Oshodi A, Jiang Y, Dent AL, Skill NJ, Huda N, Ma J, Yang Z, Liangpunsakul S. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30. PMID: 33710653; PMCID: PMC8435051.
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Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study.

Translational research : the journal of laboratory and clinical medicine

Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S.
PMID: 34743014
Transl Res. 2022 Feb;240:87-98. doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03.

Appropriate screening tool for excessive alcohol use (EAU) is clinically important as it may help providers encourage early intervention and prevent adverse outcomes. We hypothesized that patients with excessive alcohol use will have distinct serum metabolites when compared to...

Cite
Liu D, Yang Z, Chandler K, et al. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2021;240:87-98doi: 10.1016/j.trsl.2021.10.008.
Liu, D., Yang, Z., Chandler, K., Oshodi, A., Zhang, T., Ma, J., Kusumanchi, P., Huda, N., Heathers, L., Perez, K., Tyler, K., Ross, R. A., Jiang, Y., Zhang, D., Zhang, M., & Liangpunsakul, S. (2022). Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Translational research : the journal of laboratory and clinical medicine, 24087-98. https://doi.org/10.1016/j.trsl.2021.10.008
Liu, Danni, et al. "Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study." Translational research : the journal of laboratory and clinical medicine vol. 240 (2022): 87-98. doi: https://doi.org/10.1016/j.trsl.2021.10.008
Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2022 Feb;240:87-98. doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03. PMID: 34743014.
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Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease.

Biomedicines

Jiang Y, Zhang T, Kusumanchi P, Han S, Yang Z, Liangpunsakul S.
PMID: 32143280
Biomedicines. 2020 Mar 04;8(3). doi: 10.3390/biomedicines8030050.

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase

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Jiang Y, Zhang T, Kusumanchi P, et al. Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease. Biomedicines. 2020;8(3)doi: 10.3390/biomedicines8030050.
Jiang, Y., Zhang, T., Kusumanchi, P., Han, S., Yang, Z., & Liangpunsakul, S. (2020). Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease. Biomedicines, 8(3), . https://doi.org/10.3390/biomedicines8030050
Jiang, Yanchao, et al. "Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease." Biomedicines vol. 8,3 (2020). doi: https://doi.org/10.3390/biomedicines8030050
Jiang Y, Zhang T, Kusumanchi P, Han S, Yang Z, Liangpunsakul S. Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease. Biomedicines. 2020 Mar 04;8(3). doi: 10.3390/biomedicines8030050. PMID: 32143280; PMCID: PMC7148483.
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Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases.

Frontiers in medicine

Zhang T, Yang Z, Kusumanchi P, Han S, Liangpunsakul S.
PMID: 32083086
Front Med (Lausanne). 2020 Jan 31;7:7. doi: 10.3389/fmed.2020.00007. eCollection 2020.

MicroRNAs are small non-coding RNAs that range in length from 18 to 24 nucleotides. As one of the most extensively studied microRNAs, microRNA-21 (miR-21) is highly expressed in many mammalian cell types. It regulates multiple biological functions such as...

Cite
Zhang T, Yang Z, Kusumanchi P, et al. Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases. Front Med (Lausanne). 2020;7:7doi: 10.3389/fmed.2020.00007.
Zhang, T., Yang, Z., Kusumanchi, P., Han, S., & Liangpunsakul, S. (2020). Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases. Frontiers in medicine, 77. https://doi.org/10.3389/fmed.2020.00007
Zhang, Ting, et al. "Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases." Frontiers in medicine vol. 7 (2020): 7. doi: https://doi.org/10.3389/fmed.2020.00007
Zhang T, Yang Z, Kusumanchi P, Han S, Liangpunsakul S. Critical Role of microRNA-21 in the Pathogenesis of Liver Diseases. Front Med (Lausanne). 2020 Jan 31;7:7. doi: 10.3389/fmed.2020.00007. eCollection 2020. PMID: 32083086; PMCID: PMC7005070.
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Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis.

Liver research

Hollister K, Kusumanchi P, Ross RA, Chandler K, Oshodi A, Heathers L, Teagarden S, Wang L, Dent AL, Liangpunsakul S.
PMID: 30221017
Liver Res. 2018 Mar;2(1):52-59. doi: 10.1016/j.livres.2018.02.001. Epub 2018 Feb 22.

BACKGROUND: Excessive drinkers (ED) and patients with alcoholic liver disease (ALD) are several times more susceptible to bacterial and viral infections and have a decrease in antibody responses to vaccinations. Follicular helper T (TFH) cells are essential to select...

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Hollister K, Kusumanchi P, Ross RA, et al. Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis. Liver Res. 2018;2(1):52-59doi: 10.1016/j.livres.2018.02.001.
Hollister, K., Kusumanchi, P., Ross, R. A., Chandler, K., Oshodi, A., Heathers, L., Teagarden, S., Wang, L., Dent, A. L., & Liangpunsakul, S. (2018). Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis. Liver research, 2(1), 52-59. https://doi.org/10.1016/j.livres.2018.02.001
Hollister, Kristin, et al. "Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis." Liver research vol. 2,1 (2018): 52-59. doi: https://doi.org/10.1016/j.livres.2018.02.001
Hollister K, Kusumanchi P, Ross RA, Chandler K, Oshodi A, Heathers L, Teagarden S, Wang L, Dent AL, Liangpunsakul S. Levels of circulating follicular helper T cells, T helper 1 cells, and the prognostic significance of soluble form of CD40 ligand on survival in patients with alcoholic cirrhosis. Liver Res. 2018 Mar;2(1):52-59. doi: 10.1016/j.livres.2018.02.001. Epub 2018 Feb 22. PMID: 30221017; PMCID: PMC6136446.
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Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study.

Translational research : the journal of laboratory and clinical medicine

Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S.
PMID: 34743014
Transl Res. 2021 Nov 03; doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03.

Appropriate screening tool for excessive alcohol use (EAU) is clinically important as it may help providers encourage early intervention and prevent adverse outcomes. We hypothesized that patients with excessive alcohol use will have distinct serum metabolites when compared to...

Cite
Liu D, Yang Z, Chandler K, et al. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2021;doi: 10.1016/j.trsl.2021.10.008.
Liu, D., Yang, Z., Chandler, K., Oshodi, A., Zhang, T., Ma, J., Kusumanchi, P., Huda, N., Heathers, L., Perez, K., Tyler, K., Ross, R. A., Jiang, Y., Zhang, D., Zhang, M., & Liangpunsakul, S. (2021). Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Translational research : the journal of laboratory and clinical medicine, . https://doi.org/10.1016/j.trsl.2021.10.008
Liu, Danni, et al. "Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study." Translational research : the journal of laboratory and clinical medicine vol. (2021). doi: https://doi.org/10.1016/j.trsl.2021.10.008
Liu D, Yang Z, Chandler K, Oshodi A, Zhang T, Ma J, Kusumanchi P, Huda N, Heathers L, Perez K, Tyler K, Ross RA, Jiang Y, Zhang D, Zhang M, Liangpunsakul S. Serum metabolomic analysis reveals several novel metabolites in association with excessive alcohol use - an exploratory study. Transl Res. 2021 Nov 03; doi: 10.1016/j.trsl.2021.10.008. Epub 2021 Nov 03. PMID: 34743014.
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Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans.

Hepatology communications

Yang Z, Kusumanchi P, Ross RA, Heathers L, Chandler K, Oshodi A, Thoudam T, Li F, Wang L, Liangpunsakul S.
PMID: 30976744
Hepatol Commun. 2019 Feb 20;3(4):542-557. doi: 10.1002/hep4.1322. eCollection 2019 Apr.

Alcoholic liver disease (ALD) develops in a subset of heavy drinkers (HDs). The goals of our study were to (1) characterize the global serum metabolomic changes in well-characterized cohorts of controls (Cs), HDs, and those with alcoholic cirrhosis (AC);...

Cite
Yang Z, Kusumanchi P, Ross RA, et al. Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans. Hepatol Commun. 2019;3(4):542-557doi: 10.1002/hep4.1322.
Yang, Z., Kusumanchi, P., Ross, R. A., Heathers, L., Chandler, K., Oshodi, A., Thoudam, T., Li, F., Wang, L., & Liangpunsakul, S. (2019). Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans. Hepatology communications, 3(4), 542-557. https://doi.org/10.1002/hep4.1322
Yang, Zhihong, et al. "Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans." Hepatology communications vol. 3,4 (2019): 542-557. doi: https://doi.org/10.1002/hep4.1322
Yang Z, Kusumanchi P, Ross RA, Heathers L, Chandler K, Oshodi A, Thoudam T, Li F, Wang L, Liangpunsakul S. Serum Metabolomic Profiling Identifies Key Metabolic Signatures Associated With Pathogenesis of Alcoholic Liver Disease in Humans. Hepatol Commun. 2019 Feb 20;3(4):542-557. doi: 10.1002/hep4.1322. eCollection 2019 Apr. PMID: 30976744; PMCID: PMC6442705.
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Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis.

Hepatology (Baltimore, Md.)

Yang Z, Zhang T, Kusumanchi P, Tang Q, Sun Z, Radaeva S, Peiffer B, Shah VH, Kamath P, Gores GJ, Sanyal A, Chalasani N, Jiang Y, Huda N, Ma J, Liangpunsakul S.
PMID: 34096637
Hepatology. 2021 Nov;74(5):2436-2451. doi: 10.1002/hep.31994. Epub 2021 Jul 26.

BACKGROUND AND AIMS: We conducted a comprehensive serum transcriptomic analysis to explore the roles of microRNAs (miRNAs) in alcohol-associated hepatitis (AH) pathogenesis and their prognostic significance.APPROACH AND RESULTS: Serum miRNA profiling was performed in 15 controls, 20 heavy drinkers...

Cite
Yang Z, Zhang T, Kusumanchi P, et al. Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology. 2021;74(5):2436-2451doi: 10.1002/hep.31994.
Yang, Z., Zhang, T., Kusumanchi, P., Tang, Q., Sun, Z., Radaeva, S., Peiffer, B., Shah, V. H., Kamath, P., Gores, G. J., Sanyal, A., Chalasani, N., Jiang, Y., Huda, N., Ma, J., & Liangpunsakul, S. (2021). Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology (Baltimore, Md.), 74(5), 2436-2451. https://doi.org/10.1002/hep.31994
Yang, Zhihong, et al. "Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis." Hepatology (Baltimore, Md.) vol. 74,5 (2021): 2436-2451. doi: https://doi.org/10.1002/hep.31994
Yang Z, Zhang T, Kusumanchi P, Tang Q, Sun Z, Radaeva S, Peiffer B, Shah VH, Kamath P, Gores GJ, Sanyal A, Chalasani N, Jiang Y, Huda N, Ma J, Liangpunsakul S. Transcriptomic Analysis Reveals the MicroRNAs Responsible for Liver Regeneration Associated With Mortality in Alcohol-Associated Hepatitis. Hepatology. 2021 Nov;74(5):2436-2451. doi: 10.1002/hep.31994. Epub 2021 Jul 26. PMID: 34096637; PMCID: PMC8542623.
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Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling.

Hepatology (Baltimore, Md.)

Kusumanchi P, Liang T, Zhang T, Ross RA, Han S, Chandler K, Oshodi A, Jiang Y, Dent AL, Skill NJ, Huda N, Ma J, Yang Z, Liangpunsakul S.
PMID: 33710653
Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30.

BACKGROUND AND AIMS: Chronic alcohol drinking is a major risk factor for alcohol-associated liver disease (ALD). FK506-binding protein 51 (FKBP5), a cochaperone protein, is involved in many key regulatory pathways. It is known to be involved in stress-related disorders,...

Cite
Kusumanchi P, Liang T, Zhang T, et al. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology. 2021;74(3):1234-1250doi: 10.1002/hep.31800.
Kusumanchi, P., Liang, T., Zhang, T., Ross, R. A., Han, S., Chandler, K., Oshodi, A., Jiang, Y., Dent, A. L., Skill, N. J., Huda, N., Ma, J., Yang, Z., & Liangpunsakul, S. (2021). Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology (Baltimore, Md.), 74(3), 1234-1250. https://doi.org/10.1002/hep.31800
Kusumanchi, Praveen, et al. "Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling." Hepatology (Baltimore, Md.) vol. 74,3 (2021): 1234-1250. doi: https://doi.org/10.1002/hep.31800
Kusumanchi P, Liang T, Zhang T, Ross RA, Han S, Chandler K, Oshodi A, Jiang Y, Dent AL, Skill NJ, Huda N, Ma J, Yang Z, Liangpunsakul S. Stress-Responsive Gene FK506-Binding Protein 51 Mediates Alcohol-Induced Liver Injury Through the Hippo Pathway and Chemokine (C-X-C Motif) Ligand 1 Signaling. Hepatology. 2021 Sep;74(3):1234-1250. doi: 10.1002/hep.31800. Epub 2021 Aug 30. PMID: 33710653; PMCID: PMC8435051.
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The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease.

JCI insight

Yang Z, Smalling RV, Huang Y, Jiang Y, Kusumanchi P, Bogaert W, Wang L, Delker DA, Skill NJ, Han S, Zhang T, Ma J, Huda N, Liangpunsakul S.
PMID: 34423788
JCI Insight. 2021 Aug 23;6(16). doi: 10.1172/jci.insight.140687.

Alcohol-associated liver disease (ALD) represents a spectrum of histopathological changes, including alcoholic steatosis, steatohepatitis, and cirrhosis. One of the early responses to excessive alcohol consumption is lipid accumulation in the hepatocytes. Lipid ω-hydroxylation of medium- and long-chain fatty acid...

Cite
Yang Z, Smalling RV, Huang Y, et al. The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease. JCI Insight. 2021;6(16)doi: 10.1172/jci.insight.140687.
Yang, Z., Smalling, R. V., Huang, Y., Jiang, Y., Kusumanchi, P., Bogaert, W., Wang, L., Delker, D. A., Skill, N. J., Han, S., Zhang, T., Ma, J., Huda, N., & Liangpunsakul, S. (2021). The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease. JCI insight, 6(16), . https://doi.org/10.1172/jci.insight.140687
Yang, Zhihong, et al. "The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease." JCI insight vol. 6,16 (2021). doi: https://doi.org/10.1172/jci.insight.140687
Yang Z, Smalling RV, Huang Y, Jiang Y, Kusumanchi P, Bogaert W, Wang L, Delker DA, Skill NJ, Han S, Zhang T, Ma J, Huda N, Liangpunsakul S. The role of SHP/REV-ERBα/CYP4A axis in the pathogenesis of alcohol-associated liver disease. JCI Insight. 2021 Aug 23;6(16). doi: 10.1172/jci.insight.140687. PMID: 34423788; PMCID: PMC8410014.
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