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Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea.

Early education and development

Maruyama H, Ujiie T, Takai J, Takahama Y, Sakagami H, Shibayama M, Fukumoto M, Ninomiya K, Hyang Ah P, Feng X, Takatsuji C, Hirose M, Kudo R, Shima Y, Nakayama R, Hamaie N, Zhang F, Moriizumi S.
PMID: 26430351
Early Educ Dev. 2015 Nov 17;26(8):1210-1233. doi: 10.1080/10409289.2015.1036344. Epub 2015 May 26.

No abstract available.

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Maruyama H, Ujiie T, Takai J, et al. Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea. Early Educ Dev. 2015;26(8):1210-1233doi: 10.1080/10409289.2015.1036344.
Maruyama, H., Ujiie, T., Takai, J., Takahama, Y., Sakagami, H., Shibayama, M., Fukumoto, M., Ninomiya, K., Hyang Ah, P., Feng, X., Takatsuji, C., Hirose, M., Kudo, R., Shima, Y., Nakayama, R., Hamaie, N., Zhang, F., & Moriizumi, S. (2015). Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea. Early education and development, 26(8), 1210-1233. https://doi.org/10.1080/10409289.2015.1036344
Maruyama, Hiroki, et al. "Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea." Early education and development vol. 26,8 (2015): 1210-1233. doi: https://doi.org/10.1080/10409289.2015.1036344
Maruyama H, Ujiie T, Takai J, Takahama Y, Sakagami H, Shibayama M, Fukumoto M, Ninomiya K, Hyang Ah P, Feng X, Takatsuji C, Hirose M, Kudo R, Shima Y, Nakayama R, Hamaie N, Zhang F, Moriizumi S. Cultural Difference in Conflict Management Strategies of Children and Its Development: Comparing 3- and 5-Year-Olds Across China, Japan, and Korea. Early Educ Dev. 2015 Nov 17;26(8):1210-1233. doi: 10.1080/10409289.2015.1036344. Epub 2015 May 26. PMID: 26430351; PMCID: PMC4566905.
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Purification and Characterization of a Thermostable Trehalose Synthase from Thermus aquaticus.

Bioscience, biotechnology, and biochemistry

Nishimoto T, Nakada T, Chaen H, Fukuda S, Sugimoto T, Kurimoto M, Tsujisaka Y.
PMID: 27281143
Biosci Biotechnol Biochem. 1996 Jan;60(5):835-9. doi: 10.1271/bbb.60.835.

Thermostable trehalose synthase, which catalyzes the conversion of maltose into trehalose by intramolecular transglucosylation, was purified from a cell-free extract of the thermophilic bacterium Thermus aquaticus ATCC 33923 to an electrophoretically homogeneity by successive column chromatographies. The purified enzyme...

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Nishimoto T, Nakada T, Chaen H, et al. Purification and Characterization of a Thermostable Trehalose Synthase from Thermus aquaticus. Biosci Biotechnol Biochem. 1996;60(5):835-9doi: 10.1271/bbb.60.835.
Nishimoto, T., Nakada, T., Chaen, H., Fukuda, S., Sugimoto, T., Kurimoto, M., & Tsujisaka, Y. (1996). Purification and Characterization of a Thermostable Trehalose Synthase from Thermus aquaticus. Bioscience, biotechnology, and biochemistry, 60(5), 835-9. https://doi.org/10.1271/bbb.60.835
Nishimoto, T, et al. "Purification and Characterization of a Thermostable Trehalose Synthase from Thermus aquaticus." Bioscience, biotechnology, and biochemistry vol. 60,5 (1996): 835-9. doi: https://doi.org/10.1271/bbb.60.835
Nishimoto T, Nakada T, Chaen H, Fukuda S, Sugimoto T, Kurimoto M, Tsujisaka Y. Purification and Characterization of a Thermostable Trehalose Synthase from Thermus aquaticus. Biosci Biotechnol Biochem. 1996 Jan;60(5):835-9. doi: 10.1271/bbb.60.835. PMID: 27281143.
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A case of a vitreomacular traction-associated macular microhole in an eye with focal choroidal excavation.

Case reports in ophthalmology

Fukumoto M, Morishita S, Okuda Y, Suzuki H, Sato T, Kida T, Ikeda T.
PMID: 25802509
Case Rep Ophthalmol. 2015 Feb 21;6(1):71-5. doi: 10.1159/000377667. eCollection 2015.

PURPOSE: It was the aim of this study to report a case of a vitreomacular traction-associated macular microhole (MMH) in an eye with focal choroidal excavation (FCE) detected by spectral-domain optical coherence tomography (SD-OCT).PATIENTS AND METHODS: A 38-year-old Japanese...

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Fukumoto M, Morishita S, Okuda Y, et al. A case of a vitreomacular traction-associated macular microhole in an eye with focal choroidal excavation. Case Rep Ophthalmol. 2015;6(1):71-5doi: 10.1159/000377667.
Fukumoto, M., Morishita, S., Okuda, Y., Suzuki, H., Sato, T., Kida, T., & Ikeda, T. (2015). A case of a vitreomacular traction-associated macular microhole in an eye with focal choroidal excavation. Case reports in ophthalmology, 6(1), 71-5. https://doi.org/10.1159/000377667
Fukumoto, Masanori, et al. "A case of a vitreomacular traction-associated macular microhole in an eye with focal choroidal excavation." Case reports in ophthalmology vol. 6,1 (2015): 71-5. doi: https://doi.org/10.1159/000377667
Fukumoto M, Morishita S, Okuda Y, Suzuki H, Sato T, Kida T, Ikeda T. A case of a vitreomacular traction-associated macular microhole in an eye with focal choroidal excavation. Case Rep Ophthalmol. 2015 Feb 21;6(1):71-5. doi: 10.1159/000377667. eCollection 2015. PMID: 25802509; PMCID: PMC4357680.
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Measurement of serum and vitreous concentrations of anti-type II collagen antibody in diabetic retinopathy.

Clinical ophthalmology (Auckland, N.Z.)

Nakaizumi A, Fukumoto M, Kida T, Suzuki H, Morishita S, Satou T, Oku H, Ikeda T, Nakamura K.
PMID: 25848204
Clin Ophthalmol. 2015 Mar 20;9:543-7. doi: 10.2147/OPTH.S75422. eCollection 2015.

BACKGROUND: Autoimmune mechanisms have been postulated as a cause of diabetic retinopathy (DR), as several autoantibodies have reportedly been detected in the serum of DR patients. In this present study, we measured serum and vitreous levels of anti-type II...

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Nakaizumi A, Fukumoto M, Kida T, et al. Measurement of serum and vitreous concentrations of anti-type II collagen antibody in diabetic retinopathy. Clin Ophthalmol. 2015;9:543-7doi: 10.2147/OPTH.S75422.
Nakaizumi, A., Fukumoto, M., Kida, T., Suzuki, H., Morishita, S., Satou, T., Oku, H., Ikeda, T., & Nakamura, K. (2015). Measurement of serum and vitreous concentrations of anti-type II collagen antibody in diabetic retinopathy. Clinical ophthalmology (Auckland, N.Z.), 9543-7. https://doi.org/10.2147/OPTH.S75422
Nakaizumi, Atsuko, et al. "Measurement of serum and vitreous concentrations of anti-type II collagen antibody in diabetic retinopathy." Clinical ophthalmology (Auckland, N.Z.) vol. 9 (2015): 543-7. doi: https://doi.org/10.2147/OPTH.S75422
Nakaizumi A, Fukumoto M, Kida T, Suzuki H, Morishita S, Satou T, Oku H, Ikeda T, Nakamura K. Measurement of serum and vitreous concentrations of anti-type II collagen antibody in diabetic retinopathy. Clin Ophthalmol. 2015 Mar 20;9:543-7. doi: 10.2147/OPTH.S75422. eCollection 2015. PMID: 25848204; PMCID: PMC4376299.
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Vitreous estrogen levels in patients with an idiopathic macular hole.

Clinical ophthalmology (Auckland, N.Z.)

Inokuchi N, Ikeda T, Nakamura K, Morishita S, Fukumoto M, Kida T, Oku H.
PMID: 25848205
Clin Ophthalmol. 2015 Mar 20;9:549-52. doi: 10.2147/OPTH.S80754. eCollection 2015.

PURPOSE: Estrogen, a female hormone, activates collagenase and might be associated with the pathogenesis of vitreoretinal collagen fiber disease. The purpose of the present study was to investigate the vitreous levels of estrone (E1) and estradiol (E2) in subjects...

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Inokuchi N, Ikeda T, Nakamura K, et al. Vitreous estrogen levels in patients with an idiopathic macular hole. Clin Ophthalmol. 2015;9:549-52doi: 10.2147/OPTH.S80754.
Inokuchi, N., Ikeda, T., Nakamura, K., Morishita, S., Fukumoto, M., Kida, T., & Oku, H. (2015). Vitreous estrogen levels in patients with an idiopathic macular hole. Clinical ophthalmology (Auckland, N.Z.), 9549-52. https://doi.org/10.2147/OPTH.S80754
Inokuchi, Naoki, et al. "Vitreous estrogen levels in patients with an idiopathic macular hole." Clinical ophthalmology (Auckland, N.Z.) vol. 9 (2015): 549-52. doi: https://doi.org/10.2147/OPTH.S80754
Inokuchi N, Ikeda T, Nakamura K, Morishita S, Fukumoto M, Kida T, Oku H. Vitreous estrogen levels in patients with an idiopathic macular hole. Clin Ophthalmol. 2015 Mar 20;9:549-52. doi: 10.2147/OPTH.S80754. eCollection 2015. PMID: 25848205; PMCID: PMC4376308.
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A Case of Coats' Disease with Spontaneous Retinal Reattachment after Total Detachment.

Case reports in ophthalmology

Ochi R, Sato B, Mimura M, Morishita S, Fukumoto M, Kida T, Sugasawa J, Ikeda T.
PMID: 26265905
Case Rep Ophthalmol. 2015 Jun 23;6(2):200-3. doi: 10.1159/000434676. eCollection 2015.

PURPOSE: To report a case of Coats' disease in which spontaneous reattachment occurred after total retinal detachment.PATIENT AND METHODS: A young boy (patient age: 4 years and 11 months) presented with leukocoria in the left eye. Slit-lamp examination revealed...

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Ochi R, Sato B, Mimura M, et al. A Case of Coats' Disease with Spontaneous Retinal Reattachment after Total Detachment. Case Rep Ophthalmol. 2015;6(2):200-3doi: 10.1159/000434676.
Ochi, R., Sato, B., Mimura, M., Morishita, S., Fukumoto, M., Kida, T., Sugasawa, J., & Ikeda, T. (2015). A Case of Coats' Disease with Spontaneous Retinal Reattachment after Total Detachment. Case reports in ophthalmology, 6(2), 200-3. https://doi.org/10.1159/000434676
Ochi, Ryosuke, et al. "A Case of Coats' Disease with Spontaneous Retinal Reattachment after Total Detachment." Case reports in ophthalmology vol. 6,2 (2015): 200-3. doi: https://doi.org/10.1159/000434676
Ochi R, Sato B, Mimura M, Morishita S, Fukumoto M, Kida T, Sugasawa J, Ikeda T. A Case of Coats' Disease with Spontaneous Retinal Reattachment after Total Detachment. Case Rep Ophthalmol. 2015 Jun 23;6(2):200-3. doi: 10.1159/000434676. eCollection 2015. PMID: 26265905; PMCID: PMC4519598.
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A Japanese family with popliteal pterygium syndrome.

Case reports in plastic surgery & hand surgery

Katsube M, Yoshiura K, Kusumoto K.
PMID: 27252970
Case Reports Plast Surg Hand Surg. 2015 Apr 24;2(3):50-2. doi: 10.3109/23320885.2015.1038347. eCollection 2015.

We investigated a family in which the mother and a daughter suffered from popliteal pterygium syndrome (PPS). Mutation in the interferon regulatory factor 6 (IRF6) gene was detected in the mother and daughter. This is the second report of...

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Katsube M, Yoshiura K, Kusumoto K. A Japanese family with popliteal pterygium syndrome. Case Reports Plast Surg Hand Surg. 2015;2(3):50-2doi: 10.3109/23320885.2015.1038347.
Katsube, M., Yoshiura, K., & Kusumoto, K. (2015). A Japanese family with popliteal pterygium syndrome. Case reports in plastic surgery & hand surgery, 2(3), 50-2. https://doi.org/10.3109/23320885.2015.1038347
Katsube, Motoki, et al. "A Japanese family with popliteal pterygium syndrome." Case reports in plastic surgery & hand surgery vol. 2,3 (2015): 50-2. doi: https://doi.org/10.3109/23320885.2015.1038347
Katsube M, Yoshiura K, Kusumoto K. A Japanese family with popliteal pterygium syndrome. Case Reports Plast Surg Hand Surg. 2015 Apr 24;2(3):50-2. doi: 10.3109/23320885.2015.1038347. eCollection 2015. PMID: 27252970; PMCID: PMC4793797.
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Determination of Inorganic Anions in Seawater Samples by Ion Chromatography with Ultraviolet Detection Using Monolithic Octadecylsilyl Columns Coated with Dodecylammonium Cation.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry

Horioka Y, Kusumoto R, Yamane K, Nomura R, Hirokawa T, Ito K.
PMID: 27725615
Anal Sci. 2016;32(10):1123-1128. doi: 10.2116/analsci.32.1123.

A fast and sensitive ion chromatographic method for the simultaneous determinations of six inorganic anions [iodate (IO

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Horioka Y, Kusumoto R, Yamane K, et al. Determination of Inorganic Anions in Seawater Samples by Ion Chromatography with Ultraviolet Detection Using Monolithic Octadecylsilyl Columns Coated with Dodecylammonium Cation. Anal Sci. 2016;32(10):1123-1128doi: 10.2116/analsci.32.1123.
Horioka, Y., Kusumoto, R., Yamane, K., Nomura, R., Hirokawa, T., & Ito, K. (2016). Determination of Inorganic Anions in Seawater Samples by Ion Chromatography with Ultraviolet Detection Using Monolithic Octadecylsilyl Columns Coated with Dodecylammonium Cation. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 32(10), 1123-1128. https://doi.org/10.2116/analsci.32.1123
Horioka, Yuuta, et al. "Determination of Inorganic Anions in Seawater Samples by Ion Chromatography with Ultraviolet Detection Using Monolithic Octadecylsilyl Columns Coated with Dodecylammonium Cation." Analytical sciences : the international journal of the Japan Society for Analytical Chemistry vol. 32,10 (2016): 1123-1128. doi: https://doi.org/10.2116/analsci.32.1123
Horioka Y, Kusumoto R, Yamane K, Nomura R, Hirokawa T, Ito K. Determination of Inorganic Anions in Seawater Samples by Ion Chromatography with Ultraviolet Detection Using Monolithic Octadecylsilyl Columns Coated with Dodecylammonium Cation. Anal Sci. 2016;32(10):1123-1128. doi: 10.2116/analsci.32.1123. PMID: 27725615.
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Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits.

Oncotarget

Yoshida T, Ri M, Kanamori T, Aoki S, Ashour R, Kinoshita S, Narita T, Totani H, Masaki A, Ito A, Kusumoto S, Ishida T, Komatsu H, Kitahata S, Chiba T, Ichikawa S, Iida S.
PMID: 29515784
Oncotarget. 2018 Jan 11;9(11):9975-9991. doi: 10.18632/oncotarget.24160. eCollection 2018 Feb 09.

Proteasome inhibitors (PI), mainly targeting the β5 subunit of the 20S proteasome, are widely used in the treatment of multiple myeloma (MM). However, PI resistance remains an unresolved problem in the therapy of relapsed and refractory MM. To develop...

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Yoshida T, Ri M, Kanamori T, et al. Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits. Oncotarget. 2018;9(11):9975-9991doi: 10.18632/oncotarget.24160.
Yoshida, T., Ri, M., Kanamori, T., Aoki, S., Ashour, R., Kinoshita, S., Narita, T., Totani, H., Masaki, A., Ito, A., Kusumoto, S., Ishida, T., Komatsu, H., Kitahata, S., Chiba, T., Ichikawa, S., & Iida, S. (2018). Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits. Oncotarget, 9(11), 9975-9991. https://doi.org/10.18632/oncotarget.24160
Yoshida, Takashi, et al. "Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits." Oncotarget vol. 9,11 (2018): 9975-9991. doi: https://doi.org/10.18632/oncotarget.24160
Yoshida T, Ri M, Kanamori T, Aoki S, Ashour R, Kinoshita S, Narita T, Totani H, Masaki A, Ito A, Kusumoto S, Ishida T, Komatsu H, Kitahata S, Chiba T, Ichikawa S, Iida S. Potent anti-tumor activity of a syringolin analog in multiple myeloma: a dual inhibitor of proteasome activity targeting β2 and β5 subunits. Oncotarget. 2018 Jan 11;9(11):9975-9991. doi: 10.18632/oncotarget.24160. eCollection 2018 Feb 09. PMID: 29515784; PMCID: PMC5839415.
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MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods.

Alternatives to laboratory animals : ATLA

Ekwall B, Barile FA, Castano A, Clemedson C, Clothier RH, Dierickx P, Ekwall B, Ferro M, Fiskesjö G, Garza-Ocañas L, Gómez-Lechón MJ, Gülden M, Hall T, Isomaa B, Kahru A, Kerszman G, Kristen U, Kunimoto M, Kärenlampi S, Lewan L, Loukianov A, Ohno T, Persoone G, Romert L, Sawyer TW, Shrivastava R, Segner H, Stammati A, Tanaka N, Valentino M, Walum E, Zucco F.
PMID: 26042663
Altern Lab Anim. 1998 Aug;26:617-58.

No abstract available.

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Ekwall B, Barile FA, Castano A, et al. MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods. Altern Lab Anim. 1998;26:617-58
Ekwall, B., Barile, F. A., Castano, A., Clemedson, C., Clothier, R. H., Dierickx, P., Ekwall, B., Ferro, M., Fiskesjö, G., Garza-Ocañas, L., Gómez-Lechón, M. J., Gülden, M., Hall, T., Isomaa, B., Kahru, A., Kerszman, G., Kristen, U., Kunimoto, M., Kärenlampi, S., Lewan, L., Loukianov, A., Ohno, T., Persoone, G., Romert, L., Sawyer, T. W., Shrivastava, R., Segner, H., Stammati, A., Tanaka, N., Valentino, M., Walum, E., & Zucco, F. (1998). MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods. Alternatives to laboratory animals : ATLA, 26617-58.
Ekwall, B, et al. "MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods." Alternatives to laboratory animals : ATLA vol. 26 (1998): 617-58.
Ekwall B, Barile FA, Castano A, Clemedson C, Clothier RH, Dierickx P, Ekwall B, Ferro M, Fiskesjö G, Garza-Ocañas L, Gómez-Lechón MJ, Gülden M, Hall T, Isomaa B, Kahru A, Kerszman G, Kristen U, Kunimoto M, Kärenlampi S, Lewan L, Loukianov A, Ohno T, Persoone G, Romert L, Sawyer TW, Shrivastava R, Segner H, Stammati A, Tanaka N, Valentino M, Walum E, Zucco F. MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods. Altern Lab Anim. 1998 Aug;26:617-58. PMID: 26042663.
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Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion.

Hepatology research : the official journal of the Japan Society of Hepatology

Masuda T, Beppu T, Okabe H, Nitta H, Imai K, Hayashi H, Chikamoto A, Yamamoto K, Ikeshima S, Kuramoto M, Shimada S, Baba H.
PMID: 26670198
Hepatol Res. 2016 Sep;46(10):985-91. doi: 10.1111/hepr.12637. Epub 2016 Feb 04.

AIM: The aim of this study was to determine the predictive factors of pathological vascular invasion as contra-indicators for ablation therapy in patients with hepatocellular carcinoma (HCC) within 3 cm and three nodules without radiological vascular invasion.METHODS: Two hundred...

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Masuda T, Beppu T, Okabe H, et al. Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion. Hepatol Res. 2016;46(10):985-91doi: 10.1111/hepr.12637.
Masuda, T., Beppu, T., Okabe, H., Nitta, H., Imai, K., Hayashi, H., Chikamoto, A., Yamamoto, K., Ikeshima, S., Kuramoto, M., Shimada, S., & Baba, H. (2016). Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion. Hepatology research : the official journal of the Japan Society of Hepatology, 46(10), 985-91. https://doi.org/10.1111/hepr.12637
Masuda, Toshiro, et al. "Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion." Hepatology research : the official journal of the Japan Society of Hepatology vol. 46,10 (2016): 985-91. doi: https://doi.org/10.1111/hepr.12637
Masuda T, Beppu T, Okabe H, Nitta H, Imai K, Hayashi H, Chikamoto A, Yamamoto K, Ikeshima S, Kuramoto M, Shimada S, Baba H. Predictive factors of pathological vascular invasion in hepatocellular carcinoma within 3 cm and three nodules without radiological vascular invasion. Hepatol Res. 2016 Sep;46(10):985-91. doi: 10.1111/hepr.12637. Epub 2016 Feb 04. PMID: 26670198.
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The Retro-Hydroformylation Reaction.

Angewandte Chemie (International ed. in English)

Kusumoto S, Tatsuki T, Nozaki K.
PMID: 26089259
Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8458-61. doi: 10.1002/anie.201503620. Epub 2015 Jun 18.

Hydroformylation, a reaction that adds carbon monoxide and dihydrogen across an unsaturated carbon-carbon multiple bond, has been widely employed in the chemical industry since its discovery in 1938. In contrast, the reverse reaction, retro-hydroformylation, has seldom been studied. The...

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Kusumoto S, Tatsuki T, Nozaki K. The Retro-Hydroformylation Reaction. Angew Chem Int Ed Engl. 2015;54(29):8458-61doi: 10.1002/anie.201503620.
Kusumoto, S., Tatsuki, T., & Nozaki, K. (2015). The Retro-Hydroformylation Reaction. Angewandte Chemie (International ed. in English), 54(29), 8458-61. https://doi.org/10.1002/anie.201503620
Kusumoto, Shuhei, et al. "The Retro-Hydroformylation Reaction." Angewandte Chemie (International ed. in English) vol. 54,29 (2015): 8458-61. doi: https://doi.org/10.1002/anie.201503620
Kusumoto S, Tatsuki T, Nozaki K. The Retro-Hydroformylation Reaction. Angew Chem Int Ed Engl. 2015 Jul 13;54(29):8458-61. doi: 10.1002/anie.201503620. Epub 2015 Jun 18. PMID: 26089259.
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